Full Text Journal Articles by
Author Shaomin Cheng

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Butylphthalide Combined With Conventional Treatment Attenuates MMP-9 Levels and Increases VEGF Levels in Patients With Stroke: A Prospective Cohort Study.

Yingqiong Xiong, Juanjuan Liu, Yang Xu, Shu Xie, Xinhua Zhou, Shaomin Cheng,

<b>Background and Purpose:</b> Butylphtalide increases the vascular endothelial growth factor (VEGF) and decreases matrix metalloproteinase (MMP)-9 in animal models of stroke and might be of use in the management of stroke. To explore whether butylphthalide combined with conventional treatment can change the levels of MMP-9 and VEGF and the National ... Read more >>

Front Neurol (Frontiers in neurology)
[2021, 12:686199]

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Prevalence of hereditary breast and ovarian cancer (HBOC) predisposition gene mutations among 882 HBOC high-risk Chinese individuals.

Di Shao, Shaomin Cheng, Fengming Guo, Changbin Zhu, Yuying Yuan, Kunling Hu, Zhe Wang, Xuan Meng, Xin Jin, Yun Xiong, Xianghua Chai, Hong Li, Yu Zhang, Hongyun Zhang, Jihong Liu, Mingzhi Ye,

Identification of deleterious variants in hereditary breast and ovarian cancer (HBOC) susceptibility genes allows for increased clinical surveillance and early detection, and could predict the response to poly (ADP-ribose) polymerase (PARP) inhibitor in patients with advanced ovarian carcinomas. To determine the prevalence and clinical prediction factors for HBOC syndrome, 882 ... Read more >>

Cancer Sci (Cancer science)
[2020, 111(2):647-657]

Cited: 7 times

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Combination of Chronic Alcohol Consumption and High-Salt Intake Elicits Gut Microbial Alterations and Liver Steatosis in Mice.

Xiao Chen, Zheng Zhang, Bo Cui, Aimin Jiang, Haiteng Tao, Shaomin Cheng, Yong Liu,

Alcohol is a globally well-established cause of fatty liver disease (FLD). Increased salt consumption is associated with an increased prevalence of adipocyte hypertrophy and liver injury. In this study, high dietary salt potentiated chronic alcohol-induced hepatic damage. We explored the physiological mechanism of alcoholic FLD in the gastrointestinal tract. Male ... Read more >>

J Agric Food Chem (Journal of agricultural and food chemistry)
[2020, 68(6):1750-1759]

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Changes of B cell subsets in central pathological process of autoimmune encephalomyelitis in mice.

Yingqiong Xiong, Shaomin Cheng, Xiaomu Wu, Yue Ren, Xufang Xie,

<h4>Background</h4>Multiple sclerosis is a demyelinating and autoimmune disease and its immune response is not fully elucidated. This study was conducted to examine the pathological changes and B cell subsets in experimental autoimmune encephalomyelitis (EAE) mice, and analyze the expression of triosephosphate isomerase (TPI) and GADPH to define the role of ... Read more >>

BMC Immunol (BMC immunology)
[2019, 20(1):24]

Cited: 1 time

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Frequency of mutations in 21 hereditary breast and ovarian cancer susceptibility genes among high-risk Chinese individuals

Di Shao, Shaomin Cheng, Fengming Guo, Yuying Yuan, Kunling Hu, Zhe Wang, Xuan Meng, Xin Jin, Yun Xiong, Xianghua Chai, Hong Li, Yu Zhang, Hongyun Zhang, Jihong Liu, Mingzhi Ye,

To determine the prevalence and clinical prediction factors associated with deleterious mutations among 882 high-risk Chinese individuals who underwent multigene panel testing for hereditary breast and ovarian cancer (HBOC) risk assessment. Subjects were selected from individuals referred for genetic testing using a 21-gene panel (Oseq-BRCA) between January 2015 and March ... Read more >>

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A targeted next-generation sequencing method for identifying clinically relevant mutation profiles in lung adenocarcinoma.

Di Shao, Yongping Lin, Jilong Liu, Liang Wan, Zu Liu, Shaomin Cheng, Lingna Fei, Rongqing Deng, Jian Wang, Xi Chen, Liping Liu, Xia Gu, Wenhua Liang, Ping He, Jun Wang, Mingzhi Ye, Jianxing He,

Molecular profiling of lung cancer has become essential for prediction of an individual's response to targeted therapies. Next-generation sequencing (NGS) is a promising technique for routine diagnostics, but has not been sufficiently evaluated in terms of feasibility, reliability, cost and capacity with routine diagnostic formalin-fixed, paraffin-embedded (FFPE) materials. Here, we ... Read more >>

Sci Rep (Scientific reports)
[2016, 6:22338]

Cited: 32 times

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Rapid diagnosis of Propionibacterium acnes infection in patient with hyperpyrexia after hematopoietic stem cell transplantation by next-generation sequencing: a case report.

Mingzhi Ye, Wei Wei, Zhikai Yang, Yingzhen Li, Shaomin Cheng, Kang Wang, Tianliangwen Zhou, Jingmeng Sun, Sha Liu, Na Ni, Hui Jiang, Hua Jiang,

<h4>Background</h4>The rapid determination of pathogenic agent is very important to clinician for guiding their clinical medication. However, current diagnostic methods are of limitation in many aspects, such as detecting range, time-consuming, specificity and sensitivity. In this report, we apply our new-developing pathogen detection method to clarify that Propionibacterium acnes is ... Read more >>

BMC Infect Dis (BMC infectious diseases)
[2016, 16:5]

Cited: 6 times

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[Regulation of sishen wan on Bax/Bcl-2 mRNA, Fas/FasL in colonic tissue from rats with colitis].

Duanyong Liu, Xiaoying Huang, Shaomin Cheng, Wenting Tong, Panting Wan, Yongmei Guan, Haimei Zhao,

<h4>Objective</h4>To evaluate therapeutic effect of Sishen Wan on experimental colitis, and explore its mechanism by expression of Bax/Bcl-2 mRNA, Fas/FasL in colonic tissue.<h4>Method</h4>Experimental colitis was induced by rectal administration of trinitrobenzene sulfonic acid (TNBS) dissolved in ethanol. The model animals were divided into four groups: the induced colitis but untreated ... Read more >>

Zhongguo Zhong Yao Za Zhi (Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica)
[2011, 36(24):3484-3488]

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[Effect of oral scorpio and scolopendra powder on T-cell subsets in peripheral blood and intestine from rats with collagen induced arthritis].

Shaomin Cheng, Haimei Zhao, Zhiqin Zuo, Yanhui Wang, Yuesheng Wang, Duanyong Liu,

<h4>Objective</h4>To observe effect of oral scorpio and scolopendra powder on T-cell subsets in peripheral blood and intestine from rats with collagen induced arthritis (CIA).<h4>Method</h4>60 rats were randomly divided into 6 groups: normal control group, model control group, low-dose scorpio and scolopendra group, middle-dose scorpio and scolopendra group, high-dose scorpio and ... Read more >>

Zhongguo Zhong Yao Za Zhi (Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica)
[2011, 36(5):633-635]

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