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Author Seulggie Choi

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Association of Antibiotics Exposure Within the First 2 Years After Birth with Subsequent Childhood Type 1 Diabetes

Dahye Lee, Seulggie Choi, Jooyoung Chang, Young Jun Park, Jae Hyun Kim, Sang Min Park,

<h4>Purpose: </h4> Antibiotics prescription in early life can cause dysbiosis, an imbalance of gut microbiota. We aimed to reveal the relationship between antibiotics exposure during the first 2 years after birth and type 1 diabetes risk in children under 8 years of age using a nationally representative data from South ... Read more >>

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Association of first, second, and third-line bDMARDs and tsDMARD with drug survival among seropositive rheumatoid arthritis patients: Cohort study in A real world setting.

Seulggie Choi, Byeongzu Ghang, Seogsong Jeong, Daein Choi, Jeong Seok Lee, Sang Min Park, Eun Young Lee,

<h4>Objectives</h4>To determine the association of first, second, and third-line biologic disease-modifying antirheumatic drugs (bDMARDs) and tofacitinib with drug survival among seropositive rheumatoid arthritis (RA) patients.<h4>Methods</h4>The study population was composed of 8,018 seropositive RA patients who were prescribed bDMARDs or tofacitinib between January 2014 and January 2019 from the Korean Health ... Read more >>

Semin Arthritis Rheum (Seminars in arthritis and rheumatism)
[2021, 51(4):685-691]

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Association of physical activity with stroke among long-term colorectal cancer survivors.

Seogsong Jeong, Gyeongsil Lee, Seulggie Choi, Kyae Hyung Kim, Jooyoung Chang, Kyuwoong Kim, Joung Sik Son, Sung Min Kim, Yun Hwan Oh, Sang Min Park,

<h4>Purpose</h4>Cancer survivors are currently considered high-risk populations for cardiovascular disease. However, no studies have directly evaluated risks and benefits of physical activity for stroke among long-term colorectal cancer survivors.<h4>Methods</h4>This large-scale observational cohort study used data from the Korean National Health Insurance Service database. Newly diagnosed colorectal cancer patients diagnosed between ... Read more >>

J Cancer Surviv (Journal of cancer survivorship : research and practice)
[2021, :]

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Associations between alcohol consumption and cardiovascular disease among long-term survivors of colorectal cancer: a population-based, retrospective cohort study.

Gyeongsil Lee, Seogsong Jeong, Seulggie Choi, Kyae Hyung Kim, Jooyoung Chang, Seong Rae Kim, Kyuwoong Kim, Joung Sik Son, Sung Min Kim, Daein Choi, Sang Min Park,

<h4>Background</h4>There is no evidence whether it is best to stop drinking alcohol at all or whether it is okay to drink a little in that light-to-moderate alcohol use was associated with low cardiovascular disease (CVD) compared to non-drinker among colorectal cancer (CRC) survivors, who are regarded as vulnerable to CVD. ... Read more >>

BMC Cancer (BMC cancer)
[2021, 21(1):710]

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Association of weight fluctuation with cardiovascular disease risk among initially obese adults.

Seogsong Jeong, Seulggie Choi, Jooyoung Chang, Kyuwoong Kim, Sung Min Kim, Seo Yun Hwang, Joung Sik Son, Gyeongsil Lee, Sang Min Park,

The association of fluctuations in body mass index with cardiovascular risk in long-term is not well understood. This study aimed to investigate cardiovascular outcomes of weight fluctuation. Total of 67,101 obese adults from the Korean National Health Insurance Service who received health examinations in three separate biennial periods were included. ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):10152]

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Association of hemoglobin level with fracture: a nationwide cohort study.

Ji Soo Kim, Seulggie Choi, Gyeongsil Lee, Yoosun Cho, Sang Min Park,

<h4>Introduction</h4>The association between hemoglobin (Hb) level including anemia and fracture has not been studied thoroughly.<h4>Materials and methods</h4>197, 187 adults ≥ 50 years from the National Health Insurance Service of Korea were studied. Hb was determined during health screening examinations in 2004 or 2005. From 1 January 2006, participants were followed up for fracture ... Read more >>

J Bone Miner Metab (Journal of bone and mineral metabolism)
[2021, :]

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Association of weight change in young adulthood with subsequent risk of hepatocellular carcinoma: a national cohort study.

Kyuwoong Kim, Seulggie Choi, Gyeongsil Lee, Joung Sik Son, Kyae Hyung Kim, Sang Min Park,

Risk of hepatocellular carcinoma (HCC) in young adults might be clinically overlooked for future HCC risk. Thus, we examined the association between weight change and future risk of developing HCC in young adults. We collected a nationwide and population-based cohort data of more than 2.2 million men and women aged ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2021, 30(3):211-219]

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Association of Hepatic Steatosis and Metabolic Dysfunction With Incident Cardiovascular Disease: A Nationwide Cohort Study

Seogsong Jeong, Yun Hwan Oh, Seulggie Choi, Jooyoung Chang, Sung Min Kim, Joung Sik Son, Gyeongsil Lee, Won Kim, Sang Min Park,

<h4>Background: </h4> /purpose: Metabolic dysfunction (MD)-associated fatty liver disease (MAFLD) is new clearer nomenclature with positive diagnostic criteria on the basis of hepatic steatosis and MD, involving exclusion criteria for nonalcoholic fatty liver disease (NAFLD). <h4>Methods: </h4>: This retrospective cohort study included 333,389 participants who received health examination between 2009 ... Read more >>

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Association between BMI variability and risk of fracture among Korean men and women: a population based study.

Yoosun Cho, Seulggie Choi, Young Ho Yun, Belong Cho, Ji-Yeob Choi, Sang Min Park,

In Korean adults aged 50 years and older, the overall risk of fractures increased with greater BMI variability among both men and women, specifically, spinal fractures for men and both spinal and hip fractures for women.<h4>Purpose</h4>The bone-health-related outcome, such as fractures due to BMI fluctuation, has been understudied within Asian ... Read more >>

Arch Osteoporos (Archives of osteoporosis)
[2021, 16(1):67]

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Association between CVDs and initiation and adherence to statin treatment in patients with newly diagnosed hypercholesterolaemia: a retrospective cohort study.

In Sun Ryou, Jooyoung Chang, Joung Sik Son, Ahryoung Ko, Seulggie Choi, Kyuwoong Kim, Sung Min Kim, Sang Min Park,

<h4>Objectives</h4>To evaluate the association between incident cardiovascular disease (CVD) and initiation and adherence to statin treatment for primary prevention of CVD in patients with newly diagnosed hypercholesterolaemia.<h4>Design</h4>A population-based retrospective cohort study.<h4>Setting</h4>This study used National Health Insurance Service-Health Screening Cohort (NHIS-HEALS) from Republic of Korea.<h4>Participants</h4>This study included 11 320 participants without previous ... Read more >>

BMJ Open (BMJ open)
[2021, 11(4):e045375]

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Changes in Body Composition Are Associated with Metabolic Changes and the Risk of Metabolic Syndrome.

Yun Hwan Oh, Seulggie Choi, Gyeongsil Lee, Joung Sik Son, Kyae Hyung Kim, Sang Min Park,

In a cohort of 190,599 participants from The National Health Insurance Service-National Health Screening (NHIS-HEALS) study, we investigated the association of changes in the predicted body composition and metabolic profiles with the risk of metabolic syndrome (MetS) in the general population, which was hitherto incompletely elucidated. At baseline and follow-up ... Read more >>

J Clin Med (Journal of clinical medicine)
[2021, 10(4):]

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Association between physical activity and subsequent cardiovascular disease among 5-year breast cancer survivors.

Kyae Hyung Kim, Seulggie Choi, Kyuwoong Kim, Jooyoung Chang, Sung Min Kim, Seong Rae Kim, Yoosun Cho, Yun Hwan Oh, Gyeongsil Lee, Joung Sik Son, Sang Min Park,

<h4>Purpose</h4>To examine the association of physical activity among long-term breast cancer survivors on the occurrence of subsequent cardiovascular disease (CVD).<h4>Methods</h4>We investigated the risk of CVD among 39,775 breast cancer patients who were newly diagnosed in 2006 and survived until 2011 within the Korean National Health Insurance Service database. Patients were ... Read more >>

Breast Cancer Res Treat (Breast cancer research and treatment)
[2021, 188(1):203-214]

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Sociodemographic Factors, Health Behaviors, and Biological Indicators Associated With Suicide Mortality Among Young Adults in South Korea: A Nationwide Cohort Study Among 15 Million Men and Women.

Yoosun Cho, Seulggie Choi, Kyuwoong Kim, Sang Min Park,

<h4>Objective</h4>The role of sociodemographic factors, health behaviors, and biological indicators as potential risk factors for suicide is relatively understudied among young adults. The aim of this study is to explore the association of these variables with the risk of death by suicide among young adults.<h4>Methods</h4>The study population consisted of 15,534,438 ... Read more >>

J Clin Psychiatry (The Journal of clinical psychiatry)
[2020, 82(1):]

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Association between social trust and the risk of cardiovascular disease in older adults in Korea: a nationwide retrospective cohort study.

Seo Eun Hwang, Seulggie Choi, Kyuwoong Kim, Jong-Koo Lee, Juhwan Oh, Sang Min Park,

<h4>Background</h4>Although social capital has been shown to be one of the important social determinants of health, the association between social trust and the risk of cardiovascular disease (CVD) is not clear yet. We aimed to investigate the association of social trust with CVD risk using a large Korean population based ... Read more >>

BMC Public Health (BMC public health)
[2020, 20(1):1844]

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Association between social trust and the risk of cardiovascular disease in older adults in Korea: a nationwide retrospective cohort study

Seo Eun Hwang, Seulggie Choi, Kyuwoong Kim, Jong-Koo Lee, Juhwan Oh, Sang Min Park,

<h4>Background: </h4> Although social capital has been shown to be one of the important social determinants of health, the association between social trust and the risk of cardiovascular disease (CVD) is not clear yet. We aimed to investigate the association of social trust with CVD risk using a large Korean ... Read more >>

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Association of community level social trust and reciprocity with mortality: a retrospective cohort study.

Seulggie Choi, Juhwan Oh, Sang Min Park, Seo Eun Hwang, Hwa-Young Lee, Kyuwoong Kim, Yugo Shobugawa, Ichiro Kawachi, Jong-Koo Lee,

<h4>Background</h4>Whether community level social capital is associated with mortality within an Asian population is yet unclear.<h4>Methods</h4>The study population was derived from the Korean National Health Insurance Service-National Sample Cohort. A total of 636,055 participants were followed-up during 2012-2013 for deaths from all causes, cardiovascular disease (CVD), cancer, and other causes. ... Read more >>

BMC Public Health (BMC public health)
[2020, 20(1):1793]

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Impact of continuity of care on cardiovascular disease risk among newly-diagnosed hypertension patients.

Daein Choi, Seulggie Choi, Hyunho Kim, Kyuwoong Kim, Nakhyun Kim, Ahryoung Ko, Kyae Hyung Kim, Joung Sik Son, Jae Moon Yun, Yoon Kim, Sang Min Park,

Several previous studies have noted benefits of maintaining continuity of care (COC), including improved patient compliance, decreased health care cost, and decreased incidence of hospitalization. However, the association of COC in hypertension patients with subsequent cardiovascular disease (CVD) risk is yet unclear. Therefore, we aimed to investigate the impact of ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):19991]

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Development of a simple nonalcoholic fatty liver disease scoring system indicative of metabolic risks and insulin resistance.

Seogsong Jeong, Kyuwoong Kim, Jooyoung Chang, Seulggie Choi, Sung Min Kim, Joung Sik Son, Gyeongsil Lee, Won Kim, Sang Min Park,

<h4>Background</h4>Nonalcoholic fatty liver disease (NAFLD) is estimated to affect approximately 30% population worldwide. However, there is yet a basic and generally implementable approach to define individuals at risk for NAFLD estimative of metabolic risk.<h4>Methods</h4>Total of 3,634 general participants without history of liver disease and alcohol consumption who received the Korean ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2020, 8(21):1414]

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Association of tibolone and dementia risk: a cohort study using Korean claims data.

Minjung Han, Jooyoung Chang, Seulggie Choi, Yoosun Cho, Gyeongsil Lee, Sang Min Park,

<h4>Objective</h4>Few studies have examined whether tibolone (TIB), a type of hormone replacement therapy widely used in Asia and Europe, affects dementia risk in postmenopausal women. Our study aims to investigate the association of TIB and dementia risk in Korean women aged 50-80 years.<h4>Methods</h4>A population-based longitudinal study was conducted using the Korean ... Read more >>

Gynecol Endocrinol (Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology)
[2021, 37(6):567-571]

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Association of change in alcohol consumption with cardiovascular disease and mortality among initial nondrinkers.

Jun Young Chang, Seulggie Choi, Sang Min Park,

There is a paucity of studies on the influence of alcohol intake among non-drinkers. We evaluated the association between an increase in alcohol consumption and primary prevention of major adverse cardiovascular events (MACE) among non-drinkers. Data collected by the National Health Insurance Service in the Korea between 2007 and 2013 ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):13419]

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Association between Social Trust and Metabolic Syndrome in a Previously Healthy Population-A Longitudinal Cohort Study in South Korea.

Hyeah Park, Seulggie Choi, Kyae Hyung Kim, EunKyo Kang, Ahryoung Ko, Sang Min Park,

<i>Background:</i> Social trust, assessed by the trustworthiness of one another in a community, is known to have beneficial effects on health outcomes. However, the impact of social trust on metabolic syndrome (MetS) is unclear. <i>Methods:</i> The study subjects were extracted from the Korean National Health Insurance Service, and social trust ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(16):]

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Association of early-onset diabetes, prediabetes and early glycaemic recovery with the risk of all-cause and cardiovascular mortality.

Sung Min Kim, Gyeongsil Lee, Seulggie Choi, Kyuwoong Kim, Su-Min Jeong, Joung Sik Son, Jae-Moon Yun, Sin Gon Kim, Seung-Sik Hwang, Seong Yong Park, Yeon-Yong Kim, Sang Min Park,

<h4>Aims/hypothesis</h4>The increasing incidence of diabetes among young adults is a disease burden; however, the effects of early-onset diabetes, prediabetes and glycaemic recovery on CVD or mortality remain unclear. We aimed to investigate the association of these factors with 10 year all-cause mortality, CVD mortality and CVD incidence in Korean young adults.<h4>Methods</h4>This ... Read more >>

Diabetologia (Diabetologia)
[2020, 63(11):2305-2314]

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Explaining the Rationale of Deep Learning Glaucoma Decisions with Adversarial Examples.

Jooyoung Chang, Jinho Lee, Ahnul Ha, Young Soo Han, Eunoo Bak, Seulggie Choi, Jae Moon Yun, Uk Kang, Il Hyung Shin, Joo Young Shin, Taehoon Ko, Ye Seul Bae, Baek-Lok Oh, Ki Ho Park, Sang Min Park,

<h4>Purpose</h4>To illustrate what is inside the so-called black box of deep learning models (DLMs) so that clinicians can have greater confidence in the conclusions of artificial intelligence by evaluating adversarial explanation on its ability to explain the rationale of DLM decisions for glaucoma and glaucoma-related findings. Adversarial explanation generates adversarial ... Read more >>

Ophthalmology (Ophthalmology)
[2021, 128(1):78-88]

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Mechanistic dissection of diabetic retinopathy using the protein-metabolite interactome.

Ambrose Teru Patrick, Weilue He, Joshua Madu, Srinivas R Sripathi, Seulggie Choi, Kook Lee, Faith Pwaniyibo Samson, Folami L Powell, Manuela Bartoli, Donghyun Jee, Diana R Gutsaeva, Wan Jin Jahng,

<h4>Purpose</h4>The current study aims to determine the molecular mechanisms of diabetic retinopathy (DR) using the protein-protein interactome and metabolome map. We examined the protein network of novel biomarkers of DR for direct (physical) and indirect (functional) interactions using clinical target proteins in different models.<h4>Methods</h4>We used proteomic tools including 2-dimensional gel ... Read more >>

J Diabetes Metab Disord (Journal of diabetes and metabolic disorders)
[2020, 19(2):829-848]

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Association between urban green space and the risk of Alzheimer's disease: A longitudinal study

Yoosun Cho, Seulggie Choi, Sumin Seo, Gyeongsil Lee, Sang Min Park,

<h4>Backgrounds: </h4>Although studies have demonstrated the beneficial effects of green spaces on general well being, the benefits of urban green spaces on Alzheimer’s disease (AD) are still unclear. In this retrospective cohort study, we sought to ascertain the connection between the presence of green spaces in urban environments and risk ... Read more >>

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