Full Text Journal Articles by
Author Sebastian Wendt

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Medical Advice for Travelers.

Sebastian Wendt, Dietmar Beier, Dennis Paquet, Henning Trawinski, André Fuchs, Christoph Lübbert,

<h4>Background</h4>In 2019, 1.5 billion international tourist trips were counted worldwide. Germany, with 70.8 million vacations lasting ≥ 5 days, was one of the populations most willing to travel. These days, even elderly and multimorbid persons regularly travel long-distance, which can be associated with significant health risks. By advising travelers and ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(Forthcoming):]

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Correction: Hill, A.; et al. Effects of Vitamin C on Organ Function in Cardiac Surgery Patients: A Systematic Review and Meta-Analysis. Nutrients 2019, 11, 2103.

Aileen Hill, Kai C Clasen, Sebastian Wendt, Ádám G Majoros, Christian Stoppe, Neill Kj Adhikari, Daren K Heyland, Carina Benstoem,

The authors thank the readers for pointing out the issues [...]. ... Read more >>

Nutrients (Nutrients)
[2020, 12(12):]

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Hypervirulent Klebsiella pneumoniae of Lineage ST66-K2 Caused Tonsillopharyngitis in a German Patient.

Kathleen Klaper, Sebastian Wendt, Christoph Lübbert, Norman Lippmann, Yvonne Pfeifer, Guido Werner,

Hypervirulent <i>Klebsiella pneumoniae</i> (hvKp) is a novel pathotype that has been rarely described in Europe. This study characterizes a hvKp isolate that caused a community-acquired infection. The hypermucoviscous <i>Klebsiella pneumoniae</i> (<i>K. pneumoniae</i>) strain 18-0005 was obtained from a German patient with tonsillopharyngitis in 2017. Antibiotic susceptibility testing was performed and ... Read more >>

Microorganisms (Microorganisms)
[2021, 9(1):]

Cited: 2 times

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Assessing the impact of institution-specific guidelines for antimicrobials on doctors' prescribing behavior at a German tertiary-care center and the additional benefits of providing a mobile application.

Sebastian G Schönherr, Sebastian Wendt, Donald Ranft, Bettina Schock, Christoph Lübbert,

<h4>Objective</h4>To assess usage patterns, perceived usability, and effects of institution-specific guidelines (ISGs) for antimicrobials on clinicians' prescribing behavior and the additional benefits of the mobile application (app), a single-center survey among medical doctors was performed.<h4>Methods</h4>The study was carried out in a 1451-bed tertiary-care academic medical center in Leipzig, Germany. To ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0241642]

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Spinal Tuberculosis.

Christoph Eckhard Heyde, Christoph Lübbert, Sebastian Wendt, Arne Rodloff, Anna Völker, Nicolas H der Höh von,

Tuberculosis is one of the most common infectious diseases worldwide. The frequency in Germany is low, however, an increase has been observed in the past few years. The incidence of extrapulmonary manifestation accounts for up to 10 to 20%. In 50% of these cases the spinal column is affected. Although ... Read more >>

Z Orthop Unfall (Zeitschrift fur Orthopadie und Unfallchirurgie)
[2021, :]

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[29-year-old man with chronic cough and pulmonary nodule after long-term stay in Mexico].

Sebastian Wendt, Martin Macholz, Christoph Lübbert,

Dtsch Med Wochenschr (Deutsche medizinische Wochenschrift (1946))
[2020, 145(23):1671-1672]

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Switching From Ceftriaxone to Cefotaxime Significantly Contributes to Reducing the Burden of Clostridioides difficile infections.

Sebastian Wendt, Donald Ranft, Arne C Rodloff, Norman Lippmann, Christoph Lübbert,

We analyzed <i>Clostridioides difficile</i> infection (CDI) rates and various antimicrobials' application densities from 2013 to 2019 at Leipzig University Hospital, Germany, by using multivariate linear regression. Ceftriaxone application was the only independent predictor of CDI incidence. Thus, antibiotics' specific pharmacokinetic and pharmacodynamic properties such as biliary excretion of ceftriaxone in ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2020, 7(9):ofaa312]

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Biomarkers in critical care nutrition.

Christian Stoppe, Sebastian Wendt, Nilesh M Mehta, Charlene Compher, Jean-Charles Preiser, Daren K Heyland, Arnold S Kristof,

The goal of nutrition support is to provide the substrates required to match the bioenergetic needs of the patient and promote the net synthesis of macromolecules required for the preservation of lean mass, organ function, and immunity. Contemporary observational studies have exposed the pervasive undernutrition of critically ill patients and ... Read more >>

Crit Care (Critical care (London, England))
[2020, 24(1):499]

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Selenoprotein P as Biomarker of Selenium Status in Clinical Trials with Therapeutic Dosages of Selenite.

Ola Brodin, Julian Hackler, Sougat Misra, Sebastian Wendt, Qian Sun, Elena Laaf, Christian Stoppe, Mikael Björnstedt, Lutz Schomburg,

Selenoprotein P (SELENOP) is an established biomarker of selenium (Se) status. Serum SELENOP becomes saturated with increasing Se intake, reaching maximal concentrations of 5-7 mg SELENOP/L at intakes of ca. 100-150 µg Se/d. A biomarker for higher Se intake is missing. We hypothesized that SELENOP may also reflect Se status ... Read more >>

Nutrients (Nutrients)
[2020, 12(4):]

Cited: 4 times

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[Typhoid and paratyphoid fever].

Henning Trawinski, Sebastian Wendt, Norman Lippmann, Sascha Heinitz, Amrei von Braun, Christoph Lübbert,

Typhoid fever and paratyphoid fever are systemic infectious diseases of global significance caused by Salmonella enterica subspecies enterica Serovar Typhi (short name: Salmonella Typhi) or Serovar Paratyphi (short name: Salmonella Paratyphi). The course of these fecal-orally transmitted diseases is mainly characterized by a high fever. Left untreated, the course of ... Read more >>

Z Gastroenterol (Zeitschrift fur Gastroenterologie)
[2020, 58(2):160-170]

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How are travellers colonized with antimicrobial-resistant bacteria?

Sebastian Wendt, Paul Böhm, Jonas Daniel, Norman Lippmann, Christoph Lübbert,

J Travel Med (Journal of travel medicine)
[2020, 27(1):]

Cited: 1 time

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Hospital-wide ELectronic medical record evaluated computerised decision support system to improve outcomes of Patients with staphylococcal bloodstream infection (HELP): study protocol for a multicentre stepped-wedge cluster randomised trial.

Stefan Hagel, Julia Gantner, Cord Spreckelsen, Claudia Fischer, Danny Ammon, Kutaiba Saleh, Lo An Phan-Vogtmann, Andrew Heidel, Susanne Müller, Alexander Helhorn, Henner Kruse, Eric Thomas, Florian Rißner, Silke Haferkamp, Jens Vorwerk, Saskia Deffge, Marc Fabian Juzek-Küpper, Norman Lippmann, Christoph Lübbert, Henning Trawinski, Sebastian Wendt, Thomas Wendt, Andreas Dürschmid, Margarethe Konik, Stefan Moritz, Daniel Tiller, Rainer Röhrig, Jonas Schulte-Coerne, Jonas Fortmann, Stephan Jonas, Oliver Witzke, Peter-Michael Rath, Mathias W Pletz, André Scherag,

<h4>Introduction</h4><i>Staphylococci</i> are the most commonly identified pathogens in bloodstream infections. Identification of <i>Staphylococcus aureus</i> in blood culture (SAB) requires a prompt and adequate clinical management. The detection of coagulase-negative staphylococci (CoNS), however, corresponds to contamination in about 75% of the cases. Nevertheless, antibiotic therapy is often initiated, which contributes to ... Read more >>

BMJ Open (BMJ open)
[2020, 10(2):e033391]

Cited: 1 time

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Furuncular Myiasis Caused by Mango Fly Larvae.

Sebastian Wendt, Henning Trawinski, Christoph Lübbert,

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2019, 116(42):719]

Cited: 0 times

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Effects of Vitamin C on Organ Function in Cardiac Surgery Patients: A Systematic Review and Meta-Analysis.

Aileen Hill, Kai C Clasen, Sebastian Wendt, Ádám G Majoros, Christian Stoppe, Neill K J Adhikari, Daren K Heyland, Carina Benstoem,

<h4>Background</h4>Cardiac surgery is associated with oxidative stress and systemic inflammation, which both contribute to postoperative organ dysfunction. Vitamin C is a pleiotropic, antioxidant, and potentially organ-protective micronutrient. Past clinical trials and meta-analyses have focused predominantly on occurrence of postoperative atrial fibrillation. Therefore, we investigated the influence of perioperative vitamin C ... Read more >>

Nutrients (Nutrients)
[2019, 11(9):]

Cited: 5 times

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Selenium-Binding Protein 1 Indicates Myocardial Stress and Risk for Adverse Outcome in Cardiac Surgery.

Ellen C D Kühn-Heid, Eike C Kühn, Julia Ney, Sebastian Wendt, Julian Seelig, Christian Schwiebert, Waldemar B Minich, Christian Stoppe, Lutz Schomburg,

Selenium-binding protein 1 (SELENBP1) is an intracellular protein that has been detected in the circulation in response to myocardial infarction. Hypoxia and cardiac surgery affect selenoprotein expression and selenium (Se) status. For this reason, we decided to analyze circulating SELENBP1 concentrations in patients (<i>n</i> = 75) necessitating cardioplegia and a ... Read more >>

Nutrients (Nutrients)
[2019, 11(9):]

Cited: 1 time

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Selenium in Cardiac Surgery.

Sebastian Wendt, Lutz Schomburg, William Manzanares, Christian Stoppe,

Selenium (Se) is an essential trace element that plays a pivotal role in many of the body's regulatory and metabolic functions, especially during times of stress. After uptake, Se is incorporated into several Se-dependent proteins, which have potent anti-inflammatory and antioxidant capacities. Several observational clinical studies have demonstrated that Se ... Read more >>

Nutr Clin Pract (Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition)
[2019, 34(4):528-539]

Cited: 1 time

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In Reply.

Sebastian Wendt, Arne C Rodloff, Christoph Lübbert,

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2019, 116(33-34):561-562]

Cited: 0 times

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Durch Zecken übertragbare Erkrankungen: Von der Lyme-Borreliose über das Q-Fieber bis zur FSME.

Sebastian Wendt, Henning Trawinski, Amrei von Braun, Christoph Lübbert,

CME (Berl) (CME (Berlin, Germany))
[2019, 16(5):53-71]

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The Diagnosis and Treatment of Pinworm Infection.

Sebastian Wendt, Henning Trawinski, Stefan Schubert, Arne C Rodloff, Joachim Mössner, Christoph Lübbert,

<h4>Background</h4>Symptomatic infection with pinworm (Enterobius vermicularis), a human pathogen, is clinically relevant in Germany, with an estimated prevalence in childhood of 2-20%. Enterobiasis can cause major mental distress. There is little systematically verified knowledge on the treatment of this condition, and there is no corresponding German guideline. This review is, ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2019, 116(13):213-219]

Cited: 5 times

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Schistosoma and Other Relevant Helminth Infections in HIV-Positive Individuals-an Overview.

Amrei von Braun, Henning Trawinski, Sebastian Wendt, Christoph Lübbert,

For many years, researchers have postulated that helminthic infections may increase susceptibility to HIV, and that immune activation may have contributed to the extensive spread of HIV in sub-Saharan Africa. In the meantime, immunological studies have provided some evidence in support of this hypothesis, while cross-sectional clinical studies were able ... Read more >>

Trop Med Infect Dis (Tropical medicine and infectious disease)
[2019, 4(2):]

Cited: 1 time

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[Polymicrobial liver abscesses and pleural empyema in a 40-year-old male after tooth extraction and closed periodontal treatment: A case report].

Thomas Schimmel, Henning Trawinski, Thomas Karlas, Sebastian Wendt, Christoph Lübbert,

We report on a 40-year-old patient who presented with fever, right upper abdominal pain, right-sided chest pain and acute dyspnea. Imaging revealed several liver abscesses, as well as extensive right pleural empyema. Sixteen weeks previously, the patient underwent tooth extraction of the third molars (18, 28, 38, 48) and a ... Read more >>

Z Gastroenterol (Zeitschrift fur Gastroenterologie)
[2019, 57(5):600-605]

Cited: 0 times

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[Meningococcal sepsis without cerebrospinal fluid abnormalities under treatment with eculizumab].

Madlen Jentzsch, Sebastian Schwind, Vladan Vucinic, Sebastian Wendt, Catalina-Suzana Stingu, Dietger Niederwieser, Lorenz Weidhase,

Infections with Neisseriameningitidis are life-threatening conditions, generally presenting as meningitis. This case of a young woman who had a history of paroxysmal nocturnal hemoglobinuria under treatment with the complement inhibitor eculizumab had been presented with septic shock. While blood cultures were positive for Neisseria meningitidis, she showed no evidence for bacterial ... Read more >>

Med Klin Intensivmed Notfmed (Medizinische Klinik, Intensivmedizin und Notfallmedizin)
[2020, 115(4):340-342]

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Intracranial hypertension and vasculitic infarction in a patient with severe cerebral melioidosis.

Christoph Lübbert, Sebastian Wendt, Caroline Sander, Anne Beeskow, Diana Becker-Rux,

Lancet Infect Dis (The Lancet. Infectious diseases)
[2018, 18(10):1160]

Cited: 1 time

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[44 year old female africa traveller with 'worm-like' structure in the stool].

Norman Lippmann, Sebastian Wendt, Christoph Lübbert,

Dtsch Med Wochenschr (Deutsche medizinische Wochenschrift (1946))
[2018, 143(1):13-14]

Cited: 0 times

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An Emerging Cause for Liver Abscesses With Poor Prognosis.

Sebastian Wendt, Christoph Lübbert, Thomas Karlas,

Gastroenterology (Gastroenterology)
[2018, 155(1):e18-e19]

Cited: 0 times

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