Full Text Journal Articles by
Author Sean Murphy

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Progressive Multifocal Leukoencephalopathy After Carboplatin and Paclitaxel Chemotherapy for Ovarian Carcinoma.

Poornima Jayadev Menon, Mary Clare McKenna, Sean Murphy,

J Oncol Pract (Journal of oncology practice)
[2019, :JOP1900196]

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Harlequin Syndrome in Acute Thalamic Hemorrhage.

Mary Clare McKenna, Poornima Menon, Shane Smyth, Sean Murphy,

Harlequin syndrome is a disorder of the autonomic nervous system. It clinically presents as a distinct line of hemifacial sympathetic denervation. We describe a case of Harlequin syndrome with co-existing central first-order Horner syndrome in the setting of a large thalamic hemorrhage with intraventricular extension. ... Read more >>

J Stroke Cerebrovasc Dis (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association)
[2019, 28(9):e127-e128]

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Amnion Membrane Hydrogel and Amnion Membrane Powder Accelerate Wound Healing in a Full Thickness Porcine Skin Wound Model.

Sean V Murphy, Aleksander Skardal, Ronald A Nelson, Khiry Sunnon, Tanya Reid, Cara Clouse, Nancy D Kock, John Jackson, Shay Soker, Anthony Atala,

There is a need for effective wound treatments that retain the bioactivity of a cellular treatment, but without the high costs and complexities associated with manufacturing, storing, and applying living biological products. Previously, we developed an amnion membrane-derived hydrogel and evaluated its wound healing properties using a mouse wound model. ... Read more >>

Stem Cells Transl Med (Stem cells translational medicine)
[2019, :]

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Obstructive sleep apnea and orthodontics: An American Association of Orthodontists White Paper.

Rolf G Behrents, Anita Valanju Shelgikar, R Scott Conley, Carlos Flores-Mir, Mark Hans, Mitchell Levine, James A McNamara, Juan Martin Palomo, Benjamin Pliska, John W Stockstill, John Wise, Sean Murphy, Norman J Nagel, Jackie Hittner,

The Board of Trustees of the American Association of Orthodontists asked a panel of medical and dental experts in sleep medicine and dental sleep medicine to create a document designed to offer guidance to practicing orthodontists on the suggested role of the specialty of orthodontics in the management of obstructive ... Read more >>

Am J Orthod Dentofacial Orthop (American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics)
[2019, 156(1):13-28.e1]

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Medical marijuana laws are associated with increases in substance use treatment admissions by pregnant women.

Angélica Meinhofer, Allison Witman, Sean M Murphy, Yuhua Bao,

BACKGROUND AND AIMS:Between 2002 and 2014, past-month marijuana use among pregnant women in the United States increased 62%, nearly twice the growth of the general population. This growth coincides with the proliferation of state medical marijuana laws (MMLs) authorizing physicians to recommend marijuana for approved conditions. We estimated the association ... Read more >>

Addiction (Addiction (Abingdon, England))
[2019, 114(9):1593-1601]

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Sex Differences in Patient Characteristics, Treatment Strategies, and Outcomes for Type 2 Myocardial Infarction.

Cian P McCarthy, Sean Murphy, Joshua A Cohen, Saad Rehman, Maeve Jones-O'Connor, David S Olshan, Avinainder Singh, Muthiah Vaduganathan, James L Januzzi, Jason H Wasfy,

J. Am. Coll. Cardiol. (Journal of the American College of Cardiology)
[2019, 73(24):3230-3232]

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Carotid Plaque Inflammation Imaged by 18F-Fluorodeoxyglucose Positron Emission Tomography and Risk of Early Recurrent Stroke.

Peter J Kelly, Pol Camps-Renom, Nicola Giannotti, Joan Martí-Fàbregas, Sean Murphy, Jonathan McNulty, Mary Barry, Patrick Barry, David Calvet, Shelagh B Coutts, Simon Cronin, Raquel Delgado-Mederos, Eamon Dolan, Alejandro Fernández-León, Shane Foley, Joseph Harbison, Gillian Horgan, Eoin Kavanagh, Michael Marnane, Ciaran McDonnell, Martin O'Donohoe, Vijay Sharma, Cathal Walsh, David Williams, Martin O'Connell,

Background and Purpose- Plaque inflammation contributes to stroke and coronary events. 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) identifies plaque inflammation-related metabolism. Almost no prospective data exist on the relationship of carotid 18F-FDG uptake and early recurrent stroke. Methods- We did a multicenter prospective cohort study BIOVASC (Biomarkers/Imaging Vulnerable Atherosclerosis in ... Read more >>

Stroke (Stroke)
[2019, 50(7):1766-1773]

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Beyond Blood Smears: Qualification of Plasmodium 18S rRNA as a Biomarker for Controlled Human Malaria Infections.

Annette M Seilie, Ming Chang, Amelia E Hanron, Zachary P Billman, Brad C Stone, Kevin Zhou, Tayla M Olsen, Glenda Daza, Jose Ortega, Kurtis R Cruz, Nahum Smith, Sara A Healy, Jillian Neal, Carolyn K Wallis, Lisa Shelton, Tracie VonGoedert Mankowski, Sharon Wong-Madden, Sebastian A Mikolajczak, Ashley M Vaughan, Stefan H I Kappe, Matt Fishbaugher, Will Betz, Mark Kennedy, Jen C C Hume, Angela K Talley, Stephen L Hoffman, Sumana Chakravarty, B Kim Lee Sim, Thomas L Richie, Anna Wald, Christopher V Plowe, Kirsten E Lyke, Matthew Adams, Gary A Fahle, Elliot P Cowan, Patrick E Duffy, James G Kublin, Sean C Murphy,

18S rRNA is a biomarker that provides an alternative to thick blood smears in controlled human malaria infection (CHMI) trials. We reviewed data from CHMI trials at non-endemic sites that used blood smears and Plasmodium 18S rRNA/rDNA biomarker nucleic acid tests (NATs) for time to positivity. We validated a multiplex ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2019, 100(6):1466-1476]

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Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.

Duncan Wilson, Gareth Ambler, Keon-Joo Lee, Jae-Sung Lim, Masayuki Shiozawa, Masatoshi Koga, Linxin Li, Caroline Lovelock, Hugues Chabriat, Michael Hennerici, Yuen Kwun Wong, Henry Ka Fung Mak, Luis Prats-Sánchez, Alejandro Martínez-Domeño, Shigeru Inamura, Kazuhisa Yoshifuji, Ethem Murat Arsava, Solveig Horstmann, Jan Purrucker, Bonnie Yin Ka Lam, Adrian Wong, Young Dae Kim, Tae-Jin Song, Maarten Schrooten, Robin Lemmens, Sebastian Eppinger, Thomas Gattringer, Ender Uysal, Zeynep Tanriverdi, Natan M Bornstein, Einor Ben Assayag, Hen Hallevi, Jun Tanaka, Hideo Hara, Shelagh B Coutts, Lisa Hert, Alexandros Polymeris, David J Seiffge, Philippe Lyrer, Ale Algra, Jaap Kappelle, Rustam Al-Shahi Salman, Hans R Jäger, Gregory Y H Lip, Heinrich P Mattle, Leonidas D Panos, Jean-Louis Mas, Laurence Legrand, Christopher Karayiannis, Thanh Phan, Sarah Gunkel, Nicolas Christ, Jill Abrigo, Thomas Leung, Winnie Chu, Francesca Chappell, Stephen Makin, Derek Hayden, David J Williams, M Eline Kooi, Dianne H K van Dam-Nolen, Carmen Barbato, Simone Browning, Kim Wiegertjes, Anil M Tuladhar, Noortje Maaijwee, Christine Guevarra, Chathuri Yatawara, Anne-Marie Mendyk, Christine Delmaire, Sebastian Köhler, Robert van Oostenbrugge, Ying Zhou, Chao Xu, Saima Hilal, Bibek Gyanwali, Christopher Chen, Min Lou, Julie Staals, Régis Bordet, Nagaendran Kandiah, Frank-Erik de Leeuw, Robert Simister, Aad van der Lugt, Peter J Kelly, Joanna M Wardlaw, Yannie Soo, Felix Fluri, Velandai Srikanth, David Calvet, Simon Jung, Vincent I H Kwa, Stefan T Engelter, Nils Peters, Eric E Smith, Yusuke Yakushiji, Dilek Necioglu Orken, Franz Fazekas, Vincent Thijs, Ji Hoe Heo, Vincent Mok, Roland Veltkamp, Hakan Ay, Toshio Imaizumi, Beatriz Gomez-Anson, Kui Kai Lau, Eric Jouvent, Peter M Rothwell, Kazunori Toyoda, Hee-Joon Bae, Joan Marti-Fabregas, David J Werring, ,

BACKGROUND:Cerebral microbleeds are a neuroimaging biomarker of stroke risk. A crucial clinical question is whether cerebral microbleeds indicate patients with recent ischaemic stroke or transient ischaemic attack in whom the rate of future intracranial haemorrhage is likely to exceed that of recurrent ischaemic stroke when treated with antithrombotic drugs. We ... Read more >>

Lancet Neurol (The Lancet. Neurology)
[2019, 18(7):653-665]

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Cost-effectiveness of HCV Treatment Models for People Who Inject Drugs in Opioid Agonist Treatment Programs.

Sarah Gutkind, Bruce R Schackman, Jake R Morgan, Jared A Leff, Linda Agyemang, Sean M Murphy, Matthew J Akiyama, Brianna L Norton, Alain H Litwin, Benjamin P Linas,

BACKGROUND:Many people who inject drugs in the US have chronic Hepatitis C (HCV). Onsite treatment in opiate agonist treatment (OAT) programs addresses HCV treatment barriers, but few evidence-based models exist. METHODS:We evaluated the cost-effectiveness of HCV treatment models for OAT patients using data from a randomized trial conducted in Bronx, ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2019, :]

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The Cost of Inflammatory Bowel Disease: An Initiative From the Crohn's & Colitis Foundation.

K T Park, Orna G Ehrlich, John I Allen, Perry Meadows, Eva M Szigethy, Kim Henrichsen, Sandra C Kim, Rachel C Lawton, Sean M Murphy, Miguel Regueiro, David T Rubin, Nicole M Engel-Nitz, Caren A Heller,

BACKGROUND:The Crohn's & Colitis Foundation's Cost of Inflammatory Bowel Disease (IBD) Care Initiative seeks to quantify the wide-ranging health care costs affecting patients living with IBD. We aimed to (1) describe the annualized direct and indirect costs of care for patients with Crohn's disease (CD) or ulcerative colitis (UC), (2) ... Read more >>

Inflamm. Bowel Dis. (Inflammatory bowel diseases)
[2019, :]

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Malaria Parasite Density in Individuals with Different Rapid Diagnostic Test Results and Concentrations of HRP2 Antigen.

Mateusz M Plucinski, Pedro Rafael Dimbu, Filomeno Fortes, Sean C Murphy, Nahum T Smith, Kurtis R Cruz, Annette M Seilie, Eric S Halsey, Michael Aidoo, Eric Rogier,

Low-density malaria infections are a source of human morbidity in endemic settings and potentially contribute to ongoing malaria transmission. Conventional rapid diagnostic tests (RDTs) were designed to detect clinically relevant parasite and antigen levels, but it is largely unknown what proportion of parasite (and antigen positive) infections are missed by ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2019, 100(5):1202-1203]

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Implementation facilitation to promote emergency department-initiated buprenorphine for opioid use disorder: protocol for a hybrid type III effectiveness-implementation study (Project ED HEALTH).

Gail D'Onofrio, E Jennifer Edelman, Kathryn F Hawk, Michael V Pantalon, Marek C Chawarski, Patricia H Owens, Shara H Martel, Paul VanVeldhuisen, Neal Oden, Sean M Murphy, Kristen Huntley, Patrick G O'Connor, David A Fiellin,

BACKGROUND:Patients with opioid use disorder (OUD) frequently present to the emergency department (ED) after overdose, or seeking treatment for general medical conditions, their addiction, withdrawal symptoms, or complications of injection drug use, such as soft tissue infections. ED-initiated buprenorphine has been shown to be effective in increasing patient engagement in ... Read more >>

Implement Sci (Implementation science : IS)
[2019, 14(1):48]

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Misclassification of Myocardial Injury as Myocardial Infarction: Implications for Assessing Outcomes in Value-Based Programs.

Cian McCarthy, Sean Murphy, Joshua A Cohen, Saad Rehman, Maeve Jones-O'Connor, David S Olshan, Avinainder Singh, Muthiah Vaduganathan, James L Januzzi, Jason H Wasfy,

Importance:Similar to other patients with acute myocardial infarction, patients with type 2 myocardial infarction (T2MI) are included in several value-based programs, including the Hospital Readmissions Reduction Program and the Hospital Value-Based Purchasing Program. To our knowledge, whether nonischemic myocardial injury is being misclassified as T2MI is unknown and may have ... Read more >>

JAMA Cardiol (JAMA cardiology)
[2019, 4(5):460-464]

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Cystic Fibrosis Inflammation: Hyper-inflammatory, Hypo-inflammatory, or Both?

Sean V Murphy, Carla M P Ribeiro,

Am. J. Respir. Cell Mol. Biol. (American journal of respiratory cell and molecular biology)
[2019, :]

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Climate-Altered Wetlands Challenge Waterbird Use and Migratory Connectivity in Arid Landscapes.

Susan M Haig, Sean P Murphy, John H Matthews, Ivan Arismendi, Mohammad Safeeq,

Wetlands in arid landscapes provide critical habitat for millions of migratory waterbirds across the world and throughout their annual cycle. The scope and scale of understanding avian use of these wetlands in conjunction with changes in climate are daunting yet critical to address lest we lose continent-wide migratory pathways. Here, ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):4666]

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Improving estimation of puma (Puma concolor) population density: clustered camera-trapping, telemetry data, and generalized spatial mark-resight models.

Sean M Murphy, David T Wilckens, Ben C Augustine, Mark A Peyton, Glenn C Harper,

Obtaining reliable population density estimates for pumas (Puma concolor) and other cryptic, wide-ranging large carnivores is challenging. Recent advancements in spatially explicit capture-recapture models have facilitated development of novel survey approaches, such as clustered sampling designs, which can provide reliable density estimation for expansive areas with reduced effort. We applied ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):4590]

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Aspirin for the Primary Prevention of Cardiovascular Disease: Weighing Up the Evidence.

Sean Murphy, Cian P McCarthy, John W McEvoy,

Am. J. Med. (The American journal of medicine)
[2019, :]

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Underutilization of Cardiac Rehabilitation for Type 2 Myocardial Infarction.

Cian P McCarthy, Sean Murphy, Joshua A Cohen, Saad Rehman, Maeve Jones-O'Connor, David S Olshan, Avinainder Singh, Muthiah Vaduganathan, James L Januzzi, Jason H Wasfy,

J. Am. Coll. Cardiol. (Journal of the American College of Cardiology)
[2019, 73(15):2005-2007]

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Type A aortic dissection secondary to a left common carotid artery dissection.

Simon Doran, Yudy Llamas Osorio, Mark Murphy, Eoin Kavanagh, Sean Murphy,

Common carotid artery dissection is an unusual clinical event that most commonly occurs secondary to type A aortic dissection. We present a rare case of spontaneous common carotid artery dissection temporally preceding aortic dissection. Our case highlights the careful attention that cases of common carotid dissection should be given; our ... Read more >>

Radiol Case Rep (Radiology Case Reports)
[2019, 14(6):647-651]

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Will converting naloxone to over-the-counter status increase pharmacy sales?

Sean M Murphy, Jake R Morgan, Philip J Jeng, Bruce R Schackman,

OBJECTIVE:To estimate the own-price elasticity of demand for naloxone, a prescription medication that can counter the effects of an opioid overdose, and predict the change in pharmacy sales following a conversion to over-the-counter status. DATA SOURCES/STUDY SETTING:The primary data source was a nationwide prescription claims dataset for 2010-2017. The data ... Read more >>

Health Serv Res (Health services research)
[2019, 54(4):764-772]

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Why Is It Easier to Get Mad Than It Is to Feel Sad? Pilot Study of Regulation-Focused Psychotherapy for Children.

Tracy A Prout, Timothy Rice, Sean Murphy, Emma Gaines, Sophia Aizin, Danielle Sessler, Talya Ramchandani, Emma Racine, Yulia Gorokhovsky, Leon Hoffman,

OBJECTIVE::This article reports results of a pilot study of three participants receiving regulation-focused psychotherapy for children (RFP-C), a manualized, short-term, psychodynamic treatment for children with oppositional defiant disorder and other externalizing problems. RFP-C targets implicit emotion regulation while using an intensive, psychodynamic, play therapy approach to decrease the child's need ... Read more >>

Am J Psychother (American journal of psychotherapy)
[2019, 72(1):2-8]

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Long-term therapeutic effect of cell therapy on improvement in erectile function in a rat model with pelvic neurovascular injury.

Xin Gu, Hua Shi, Ethan Matz, Liren Zhong, Ting Long, Cara Clouse, Wei Li, Dong Chen, HyunChul Chung, Sean Murphy, James Yoo, Guiting Lin, Tom Lue, Anthony Atala, John Jackson, Yuanyuan Zhang,

OBJECTIVE:To determine the long-term therapeutic effect amongst three human cell types on erectile function recovery in a rat model of dual neurovascular-injury erectile dysfunction (NVED). MATERIALS AND METHODS:A dual NVED model was established in athymic rats by crushing the bilateral cavernous nerves and ligating the bilateral internal pudendal neurovascular bundles. ... Read more >>

BJU Int. (BJU international)
[2019, 124(1):145-154]

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Left Ventricular Thrombus: Contemporary Etiologies, Treatment Strategies, and Outcomes.

Cian P McCarthy, Sean Murphy, Ramkumar V Venkateswaran, Avinainder Singh, Leslie L Chang, Melvin G Joice, Jose M Rivero, Muthiah Vaduganathan, James L Januzzi, Deepak L Bhatt,

J. Am. Coll. Cardiol. (Journal of the American College of Cardiology)
[2019, 73(15):2007-2009]

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Emergency department utilization among individuals with idiopathic intracranial hypertension.

Sean Murphy, Daniel L Friesner, Robert Rosenman, Carin S Waslo, Johnathan Au, Emanuel Tanne,

PURPOSE:Idiopathic intracranial hypertension (IIH) can be a debilitating disorder that is difficult to identify and treat. Failure to adequately manage IIH symptoms may force patients to present at emergency departments (EDs) seeking symptom relief. The purpose of this paper is to empirically characterize ED use by previously diagnosed IIH patients. ... Read more >>

Int J Health Care Qual Assur (International journal of health care quality assurance)
[2019, 32(1):152-163]

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