Full Text Journal Articles by
Author Sean M Murphy

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Medical marijuana laws are associated with increases in substance use treatment admissions by pregnant women.

Angélica Meinhofer, Allison Witman, Sean M Murphy, Yuhua Bao,

BACKGROUND AND AIMS:Between 2002 and 2014, past-month marijuana use among pregnant women in the United States increased 62%, nearly twice the growth of the general population. This growth coincides with the proliferation of state medical marijuana laws (MMLs) authorizing physicians to recommend marijuana for approved conditions. We estimated the association ... Read more >>

Addiction (Addiction (Abingdon, England))
[2019, 114(9):1593-1601]

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The Cost of Inflammatory Bowel Disease: An Initiative From the Crohn's & Colitis Foundation.

K T Park, Orna G Ehrlich, John I Allen, Perry Meadows, Eva M Szigethy, Kim Henrichsen, Sandra C Kim, Rachel C Lawton, Sean M Murphy, Miguel Regueiro, David T Rubin, Nicole M Engel-Nitz, Caren A Heller,

BACKGROUND:The Crohn's & Colitis Foundation's Cost of Inflammatory Bowel Disease (IBD) Care Initiative seeks to quantify the wide-ranging health care costs affecting patients living with IBD. We aimed to (1) describe the annualized direct and indirect costs of care for patients with Crohn's disease (CD) or ulcerative colitis (UC), (2) ... Read more >>

Inflamm. Bowel Dis. (Inflammatory bowel diseases)
[2019, :]

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Implementation facilitation to promote emergency department-initiated buprenorphine for opioid use disorder: protocol for a hybrid type III effectiveness-implementation study (Project ED HEALTH).

Gail D'Onofrio, E Jennifer Edelman, Kathryn F Hawk, Michael V Pantalon, Marek C Chawarski, Patricia H Owens, Shara H Martel, Paul VanVeldhuisen, Neal Oden, Sean M Murphy, Kristen Huntley, Patrick G O'Connor, David A Fiellin,

BACKGROUND:Patients with opioid use disorder (OUD) frequently present to the emergency department (ED) after overdose, or seeking treatment for general medical conditions, their addiction, withdrawal symptoms, or complications of injection drug use, such as soft tissue infections. ED-initiated buprenorphine has been shown to be effective in increasing patient engagement in ... Read more >>

Implement Sci (Implementation science : IS)
[2019, 14(1):48]

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Cost-effectiveness of HCV Treatment Models for People Who Inject Drugs in Opioid Agonist Treatment Programs.

Sarah Gutkind, Bruce R Schackman, Jake R Morgan, Jared A Leff, Linda Agyemang, Sean M Murphy, Matthew J Akiyama, Brianna L Norton, Alain H Litwin, Benjamin P Linas,

BACKGROUND:Many people who inject drugs in the US have chronic Hepatitis C (HCV). Onsite treatment in opiate agonist treatment (OAT) programs addresses HCV treatment barriers, but few evidence-based models exist. METHODS:We evaluated the cost-effectiveness of HCV treatment models for OAT patients using data from a randomized trial conducted in Bronx, ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2019, :]

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Improving estimation of puma (Puma concolor) population density: clustered camera-trapping, telemetry data, and generalized spatial mark-resight models.

Sean M Murphy, David T Wilckens, Ben C Augustine, Mark A Peyton, Glenn C Harper,

Obtaining reliable population density estimates for pumas (Puma concolor) and other cryptic, wide-ranging large carnivores is challenging. Recent advancements in spatially explicit capture-recapture models have facilitated development of novel survey approaches, such as clustered sampling designs, which can provide reliable density estimation for expansive areas with reduced effort. We applied ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):4590]

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Will converting naloxone to over-the-counter status increase pharmacy sales?

Sean M Murphy, Jake R Morgan, Philip J Jeng, Bruce R Schackman,

OBJECTIVE:To estimate the own-price elasticity of demand for naloxone, a prescription medication that can counter the effects of an opioid overdose, and predict the change in pharmacy sales following a conversion to over-the-counter status. DATA SOURCES/STUDY SETTING:The primary data source was a nationwide prescription claims dataset for 2010-2017. The data ... Read more >>

Health Serv Res (Health services research)
[2019, 54(4):764-772]

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Cost-Effectiveness of Buprenorphine-Naloxone Versus Extended-Release Naltrexone to Prevent Opioid Relapse.

Sean M Murphy, Kathryn E McCollister, Jared A Leff, Xuan Yang, Philip J Jeng, Joshua D Lee, Edward V Nunes, Patricia Novo, John Rotrosen, Bruce R Schackman,

Background:Not enough evidence exists to compare buprenorphine-naloxone with extended-release naltrexone for treating opioid use disorder. Objective:To evaluate the cost-effectiveness of buprenorphine-naloxone versus extended-release naltrexone. Design:Cost-effectiveness analysis alongside a previously reported randomized clinical trial of 570 adults in 8 U.S. inpatient or residential treatment programs. Data Sources:Study instruments. Target Population:Adults with ... Read more >>

Ann. Intern. Med. (Annals of internal medicine)
[2018, :]

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Acute Post-Traumatic Sleep May Define Vulnerability to a Second Traumatic Brain Injury in Mice.

Rachel K Rowe, Jordan L Harrison, Helena W Morrison, Vignesh Subbian, Sean M Murphy, Jonathan Lifshitz,

Chronic neurological impairments can manifest from repetitive traumatic brain injury (rTBI), particularly when subsequent injuries occur before the initial injury completely heals. Herein, we apply post-traumatic sleep as a physiological biomarker of vulnerability, hypothesizing that a second TBI during post-traumatic sleep worsens neurological and histological outcomes compared to one TBI ... Read more >>

J. Neurotrauma (Journal of neurotrauma)
[2019, 36(8):1318-1334]

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Cost of pharmacotherapy for opioid use disorders following inpatient detoxification.

Kathryn E McCollister, Jared A Leff, Xuan Yang, Joshua D Lee, Edward V Nunes, Patricia Novo, John Rotrosen, Bruce R Schackman, Sean M Murphy,

OBJECTIVES:To estimate the costs of providing extended-release injectable naltrexone (XR-NTX) and buprenorphine-naloxone (BUP-NX) following inpatient detoxification using data derived from a multisite randomized controlled trial at 8 US community-based treatment programs. STUDY DESIGN:Cost data were collected for 3 intervention phases: program start-up, inpatient detoxification, and up to 24 weeks of ... Read more >>

Am J Manag Care (The American journal of managed care)
[2018, 24(11):526-531]

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The "Real" Number of Washington State Adolescents Using Marijuana, and Why: A Misclassification Analysis.

Sean M Murphy, Robert Rosenman,

BACKGROUND:Although causality is difficult to establish, the regular use of marijuana has been associated with many adverse physiological and sociological consequences. There is considerable concern regarding marijuana use among adolescents, as the likelihood of adverse consequences increases significantly for this age group. The most comprehensive data for identifying risk factors ... Read more >>

Subst Use Misuse (Substance use & misuse)
[2019, 54(1):89-96]

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Criminal justice measures for economic data harmonization in substance use disorder research.

Kathryn E McCollister, Xuan Yang, Sean M Murphy, Jared A Leff, Richard A Kronmal, Heidi M Crane, Redonna K Chandler, Faye S Taxman, Daniel J Feaster, Lisa R Metsch, William E Cunningham, Frederick L Altice, Bruce R Schackman,

BACKGROUND:The consequences of substance use disorders (SUDs) are varied and broad, affecting many sectors of society and the economy. Economic evaluation translates these consequences into dollars to examine the net economic impact of interventions for SUD, and associated conditions such as HCV and HIV. The nexus between substance use and ... Read more >>

Health Justice (Health & justice)
[2018, 6(1):17]

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Physician Time Burden Associated with Querying Prescription Drug Monitoring Programs.

Marcus A Bachhuber, Brendan Saloner, Marc LaRochelle, Jessica S Merlin, Brandon C Maughan, Dan Polsky, Naum Shaparin, Sean M Murphy,

Objective:Prescription drug monitoring programs (PDMPs) enable prescribers to review patient prescription histories, and their use is mandatory in many states. We estimated the cost of physicians retrieving PDMP patient reports compared with a model where a delegate (i.e., administrative staff) retrieves reports. Methods:We performed a cost analysis with a one-year ... Read more >>

Pain Med (Pain medicine (Malden, Mass.))
[2018, 19(10):1952-1960]

Cited: 2 times

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Genetic diversity, effective population size, and structure among black bear populations in the Lower Mississippi Alluvial Valley, USA

Sean M Murphy, David L. Garshelis, Jared S. Laufenberg, Jerrold L. Belant, Joseph D. Clark, Maria Davidson,

Multiple small populations of American black bears Ursus americanus, including the recently delisted Louisiana black bear subspecies U. a. luteolus, occupy a fragmented landscape in the Lower Mississippi Alluvial Valley, USA (LMAV). Populations include bears native to the LMAV, bears translocated from Minnesota during the 1960s, and recently reintroduced and ... Read more >>

Conserv. Genet. (Conservation genetics (Print))
[2018, 19(5):1055-1067]

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Predictors of tobacco and alcohol co-use from ages 15 to 32: The Amsterdam Growth and Health Longitudinal Study.

Sterling M McPherson, Ekaterina Burduli, Crystal Lederhos Smith, Olivia Brooks, Michael F Orr, Celestina Barbosa-Leiker, Trynke Hoekstra, Michael G McDonell, Sean M Murphy, Matthew Layton, John M Roll,

Tobacco and alcohol are often used in tandem over time, but specific predictors of course and patterns of course over time need explication. We examined differences in alcohol and tobacco course among an adolescent population as they transitioned into young adulthood across a 17-year period. Data came from participants (n ... Read more >>

Exp Clin Psychopharmacol (Experimental and clinical psychopharmacology)
[2018, 26(6):549-559]

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An Economic Evaluation of Coordinated Specialty Care (CSC) Services for First-Episode Psychosis in the U.S. Public Sector.

Sean M Murphy, Suat Kucukgoncu, Yuhua Bao, Fangyong Li, Cenk Tek, Nicholas J K Breitborde, Sinan Guloksuz, Vivek H Phutane, Banu Ozkan, Jessica M Pollard, John D Cahill, Scott W Woods, Robert A Cole, Michael Schoenbaum, Vinod H Srihari,

BACKGROUND:Schizophrenia spectrum disorders exert a large and disproportionate economic impact. Early intervention services may be able to alleviate the burden of schizophrenia spectrum disorders on diagnosed individuals, caregivers, and society at large. Economic analyses of observational studies have supported investments in specialized team-based care for early psychosis; however, questions remain ... Read more >>

J Ment Health Policy Econ (The journal of mental health policy and economics)
[2018, 21(3):123-130]

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Intra-abdominal complications following intestinal anastomoses by suture and staple techniques in dogs.

Christine M DePompeo, Laura Bond, Yelena E George, Marguerite J Mezzles, Jeff D Brourman, John C Chandler, Sean M Murphy, Fred Pike, David R Mason,

OBJECTIVE To compare the incidence of intra-abdominal complications in dogs following resection and functional end-to-end stapled anastomosis (FEESA) versus anastomosis with an end-to-end sutured technique for treatment of enteric lesions. DESIGN Multicenter, retrospective descriptive cohort study. ANIMALS 180 dogs. PROCEDURES Medical records of dogs undergoing intestinal resection and anastomosis at ... Read more >>

J. Am. Vet. Med. Assoc. (Journal of the American Veterinary Medical Association)
[2018, 253(4):437-443]

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Decreases in smoking during treatment for methamphetamine-use disorders: preliminary evidence.

Sterling McPherson, Michael Orr, Crystal Lederhos, Michael McDonell, Emily Leickly, Katherine Hirchak, Oladunni A Oluwoye, Sean M Murphy, Matthew Layton, John M Roll,

Despite high rates of smoking (70-90%) and the severely negative impact of smoking on physical and mental health, only 12% of individuals receiving stimulant-use disorder treatment also receive smoking-cessation treatment. The aim of this investigation was to examine the effect of a contingency management (CM) intervention targeting methamphetamine (MA) use ... Read more >>

Behav Pharmacol (Behavioural pharmacology)
[2018, 29(4):370-374]

Cited: 1 time

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Using a randomized controlled trial to test whether modifications to contingency management improve outcomes for heavy drinkers with serious mental illness.

Oladunni Oluwoye, Jordan Skalisky, Ekaterina Burduli, Naomi S Chaytor, Sterling McPherson, Sean M Murphy, Jalene Herron, Katherine Hirchak, Mason Burley, Richard K Ries, John M Roll, Michael G McDonell,

In contingency management (CM), individuals receive rewards for alcohol abstinence. CM is associated with reduced alcohol use in adults with co-occurring serious mental illnesses (SMI). Pre-treatment urine ethyl glucuronide (uEtG) levels equivalent to daily heavy drinking (uEtG >349ng/mL) are associated with poor response to CM. Modifications to CM are needed ... Read more >>

Contemp Clin Trials (Contemporary clinical trials)
[2018, 69:92-98]

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Personal Control Over Decisions to Participate in Research by Persons With Histories of Both Substance Use Disorders and Criminal Justice Supervision.

Donna T Chen, Tomohiro M Ko, Ashleigh A Allen, Richard J Bonnie, Colleen E Suratt, Paul S Appelbaum, Edward V Nunes, Peter D Friedmann, Joshua D Lee, Michael S Gordon, Ryan McDonald, Donna Wilson, Tamara Y Boney, Sean M Murphy, Charles P O'Brien,

Individuals must feel free to exert personal control over decisions regarding research participation. We present an examination of participants' perceived personal control over, as well as reported pressures and threats from others, influencing their decision to join a study assessing the effectiveness of extended-release naltrexone in preventing opioid dependence relapse. ... Read more >>

J Empir Res Hum Res Ethics (Journal of empirical research on human research ethics : JERHRE)
[2018, 13(2):160-172]

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Implementation of a nationwide health economic consultation service to assist substance use researchers: Lessons learned.

Sean M Murphy, Jared A Leff, Benjamin P Linas, Jake R Morgan, Kathryn McCollister, Bruce R Schackman,

BACKGROUND:Health economic evaluation findings assist stakeholders in improving the quality, availability, scalability, and sustainability of evidence-based services, and in maximizing the efficiency of service delivery. The Center for Health Economics of Treatment Interventions for Substance Use Disorders, HCV, and HIV (CHERISH) is a NIDA-funded multi-institutional center of excellence whose mission ... Read more >>

Subst Abus (Substance abuse)
[2018, 39(2):185-189]

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Consequences of severe habitat fragmentation on density, genetics, and spatial capture-recapture analysis of a small bear population.

Sean M Murphy, Ben C Augustine, Wade A Ulrey, Joseph M Guthrie, Brian K Scheick, J Walter McCown, John J Cox,

Loss and fragmentation of natural habitats caused by human land uses have subdivided several formerly contiguous large carnivore populations into multiple small and often isolated subpopulations, which can reduce genetic variation and lead to precipitous population declines. Substantial habitat loss and fragmentation from urban development and agriculture expansion relegated the ... Read more >>

PLoS ONE (PloS one)
[2017, 12(7):e0181849]

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Assessing informed consent in an opioid relapse prevention study with adults under current or recent criminal justice supervision.

Ashleigh A Allen, Donna T Chen, Richard J Bonnie, Tomohiro M Ko, Colleen E Suratt, Joshua D Lee, Peter D Friedmann, Michael Gordon, Ryan McDonald, Sean M Murphy, Tamara Y Boney, Edward V Nunes, Charles P O'Brien,

Concerns persist that individuals with substance use disorders who are under community criminal justice supervision experience circumstances that might compromise their provision of valid, informed consent for research participation. These concerns include the possibilities that desire to obtain access to treatment might lead individuals to ignore important information about research ... Read more >>

J Subst Abuse Treat (Journal of substance abuse treatment)
[2017, 81:66-72]

Cited: 1 time

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Seroprevalence of Toxoplasma gondii in American Black Bears ( Ursus americanus ) of the Central Appalachians, USA.

John J Cox, Sean M Murphy, Ben C Augustine, Joseph M Guthrie, John T Hast, Sutton C Maehr, Joseph McDermott,

We assessed Toxoplasma gondii seroprevalence in 53 free-ranging American black bears ( Ursus americanus ) in the Central Appalachian Mountains, US. Seroprevalence was 62% with no difference between males and females or between juvenile and adult bears. Wildlife agencies should consider warnings in hunter education programs to reduce the chances ... Read more >>

J. Wildl. Dis. (Journal of wildlife diseases)
[2017, 53(3):671-673]

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A Randomized Controlled Trial of a Citywide Emergency Department Care-Coordination Program to Reduce Prescription Opioid-Related Visits: An Economic Evaluation.

Sean M Murphy, Donelle Howell, Sterling McPherson, Rebecca Grohs, John Roll, Darin Neven,

Care provided in the emergency department (ED) can cost up to five times as much as care received for comparable diagnoses in alternative settings. Small groups of patients, many of whom suffer from an opioid use disorder, often account for a large proportion of total ED visits. We recently conducted, ... Read more >>

J Emerg Med (The Journal of emergency medicine)
[2017, 53(2):186-194]

Cited: 1 time

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Cost-effectiveness of extended release naltrexone to prevent relapse among criminal justice-involved individuals with a history of opioid use disorder.

Sean M Murphy, Daniel Polsky, Joshua D Lee, Peter D Friedmann, Timothy W Kinlock, Edward V Nunes, Richard J Bonnie, Michael Gordon, Donna T Chen, Tamara Y Boney, Charles P O'Brien,

BACKGROUND AND AIMS:Criminal justice-involved individuals are highly susceptible to opioid relapse and overdose-related deaths. In a recent randomized trial, we demonstrated the effectiveness of extended-release naltrexone (XR-NTX; Vivitrol® ) in preventing opioid relapse among criminal justice-involved US adults with a history of opioid use disorder. The cost of XR-NTX may ... Read more >>

Addiction (Addiction (Abingdon, England))
[2017, 112(8):1440-1450]

Cited: 1 time

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