Full Text Journal Articles by
Author Sean Lyons

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Does formal home care reduce inpatient length of stay?

Brendan Walsh, Seán Lyons, Samantha Smith, Maev-Ann Wren, James Eighan, Edgar Morgenroth,

Formal home care is an appropriate substitute for acute hospital care for many older people. However, limited empirical evidence exists on the extent of substitution between the supply of home care and hospital use. This study examines whether patients from areas with a better supply of home care have lower ... Read more >>

Health Econ (Health economics)
[2020, 29(12):1620-1636]

Cited: 0 times

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Demographic variation in active consumer behaviour: On-line search for retail broadband services.

Philip Carthy, Peter D Lunn, Sean Lyons,

Consumers who actively search for better broadband deals may benefit from lower prices or improved service quality compared to those who do not. If, however, consumers differ in their propensity to engage with the market and actively search, these potential benefits may not accrue equally. This paper investigates differences in ... Read more >>

Heliyon (Heliyon)
[2020, 6(7):e04478]

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Local NO2 concentrations and asthma among over-50s in Ireland: A microdata analysis.

Philip Carthy, Aonghus Ó Domhnaill, Margaret O'Mahony, Anne Nolan, Frank Moriarty, Brian Broderick, Martina Hennessy, Aoife Donnelly, Owen Naughton, Sean Lyons,

BACKGROUND:Links between air pollution and asthma are less well established for older adults than some younger groups. Nitrogen dioxide (NO2) concentrations are widely used as an indicator of transport-related air pollution, and some literature suggests NO2 may directly affect asthma. METHODS:This study used data on 8162 adults >50 years old in ... Read more >>

Int J Epidemiol (International journal of epidemiology)
[2020, :]

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Characterising urban green space density and footpath-accessibility in models of BMI.

Philip Carthy, Sean Lyons, Anne Nolan,

BACKGROUND:While exposure to urban green spaces has been associated with various physical health benefits, the evidence linking these spaces to lower BMI, particularly among older people, is mixed. We ask whether footpath availability, generally unobserved in the existing literature, may mediate exposure to urban green space and help explain this ... Read more >>

BMC Public Health (BMC public health)
[2020, 20(1):760]

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Characterising urban green space density and footpath-accessibility in models of BMI

Philip Carthy, Sean Lyons, Anne Nolan,

<h4>Background: </h4> While exposure to urban green spaces has been associated with various physical health benefits, the evidence linking these spaces to lower BMI, particularly among older people, is mixed. We ask whether footpath availability, generally unobserved in the existing literature, may mediate exposure to urban green space and help ... Read more >>

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Understanding Trends in Pesticide Volatilization from Agricultural Fields Using the Pesticide Loss via Volatilization Model.

Madeleine Taylor, Sean M Lyons, Cleo L Davie-Martin, Trudyanne S Geoghegan, Kimberly J Hageman,

The Pesticide Loss via Volatilization model was developed to predict and understand pesticide volatilization rates from a planted agricultural field. The model allows the user to adjust the properties of the pesticide, various soil and plant descriptors, and climatic conditions. A useful output from the model is the 24 h ... Read more >>

Environ Sci Technol (Environmental science & technology)
[2020, 54(4):2202-2209]

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An Examination of Myers-Briggs Type Indicator Personality, Gender, and Career Interests of Ontario Veterinary College Students.

Monika L Goetz, Andria Jones-Bitton, Joanne Hewson, Deep Khosa, David Pearl, Dorothy J Bakker, Sean T Lyons, Peter D Conlon,

The objectives of this study were to describe the Myers-Briggs Type Indicator (MBTI) distribution of Ontario Veterinary College (OVC) veterinary students (<i>n</i> = 1,249), and to evaluate its associations with gender and career interests. This was achieved by collecting pre-matriculation data from 11 graduating classes. Overall, OVC veterinary students were ... Read more >>

J Vet Med Educ (Journal of veterinary medical education)
[2020, 47(4):430-444]

Cited: 0 times

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Chronic Toxicities of Neonicotinoids to Nymphs of the Common New Zealand Mayfly Deleatidium spp.

Samuel J Macaulay, Kimberly J Hageman, Robert E Alumbaugh, Sean M Lyons, Jeremy J Piggott, Christoph D Matthaei,

Neonicotinoid insecticides have been shown to have high chronic toxicity relative to acute toxicity, and therefore short-term toxicity tests ≤96 h in duration may underestimate their environmental risks. Among nontarget aquatic invertebrates, insects of the orders Diptera and Ephemeroptera have been found to be the most sensitive to neonicotinoids. To undertake ... Read more >>

Environ Toxicol Chem (Environmental toxicology and chemistry)
[2019, 38(11):2459-2471]

Cited: 1 time

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An investigation of the effect of accessibility to General Practitioner services on healthcare utilisation among older people.

Gretta Mohan, Anne Nolan, Seán Lyons,

Equity in access to healthcare services is regarded as an important policy goal in the organisation of modern healthcare systems. Physical accessibility to healthcare services is recognised as a key component of access. Older people are more frequent and intensive users of healthcare, but reduced mobility and poorer access to ... Read more >>

Soc Sci Med (Social science & medicine (1982))
[2019, 220:254-263]

Cited: 1 time

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Coastal blue space and depression in older adults.

Seraphim Dempsey, Mel T Devine, Tom Gillespie, Seán Lyons, Anne Nolan,

This paper tests whether higher exposure to coastal blue space is associated with lower risk of depression using data from The Irish Longitudinal Study on Ageing (TILDA), a nationally representative longitudinal study of people aged fifty and over in Ireland. We contribute to the literature on blue space and health ... Read more >>

Health Place (Health & place)
[2018, 54:110-117]

Cited: 4 times

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Consumer switching intentions for telecoms services: evidence from Ireland.

Peter D Lunn, Sean Lyons,

Despite long-standing market liberalisation and efforts to reduce switching costs, many consumers have never switched telecoms provider. This paper investigates how consumer and service characteristics relate to switching intentions, using a sample of fixed-line broadband, mobile telephony and landline telephony customers from a 2015 survey conducted by ComReg, Ireland's National ... Read more >>

Heliyon (Heliyon)
[2018, 4(5):e00618]

Cited: 1 time

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Authors' reply to 'comments on high radon areas and lung cancer prevalence: evidence from Ireland'.

Seraphim Dempsey, Seán Lyons, Anne Nolan,

J Environ Radioact (Journal of environmental radioactivity)
[2018, 192:711-712]

Cited: 0 times

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Urban green space and obesity in older adults: Evidence from Ireland.

Seraphim Dempsey, Seán Lyons, Anne Nolan,

We examine the association between living in an urban area with more or less green space and the probability of being obese. This work involves the creation of a new dataset which combines geo-coded data at the individual level from the Irish Longitudinal Study on Ageing with green space data ... Read more >>

SSM Popul Health (SSM - population health)
[2018, 4:206-215]

Cited: 6 times

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High Radon Areas and lung cancer prevalence: Evidence from Ireland.

Seraphim Dempsey, Seán Lyons, Anne Nolan,

This paper examined the relationship between radon risk and lung cancer prevalence using a novel dataset combining spatially-coded survey data with a radon risk map. A logit model was employed to test for significant associations between a high risk of indoor radon and lung cancer prevalence using data on 5590 ... Read more >>

J Environ Radioact (Journal of environmental radioactivity)
[2018, 182:12-19]

Cited: 3 times

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An Exploration of the Relationship between Psychological Capital and Depression among First-Year Doctor of Veterinary Medicine Students.

Dorothy J Bakker, Sean T Lyons, Peter D Conlon,

This study examined the impact of psychological capital on depressive symptoms among Doctor of Veterinary Medicine (DVM) students (n=84) over their first two semesters of studies. Our results indicated elevated rates of depression in both the first and second semesters relative to published norms. Using the typology developed by Hafen, ... Read more >>

J Vet Med Educ (Journal of veterinary medical education)
[2017, 44(1):50-62]

Cited: 3 times

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Market power and provider consolidation in physician markets.

Samuel A Kleiner, William D White, Sean Lyons,

Physician services comprise a substantial share of total health care spending, and the price of health care services has been cited as a key contributor to the disproportionately high rate of health care spending in the US. However, despite a large literature analyzing market power in the hospital and insurance ... Read more >>

Int J Health Econ Manag (International journal of health economics and management)
[2015, 15(1):99-126]

Cited: 4 times

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Socioeconomic distribution of emissions and resource use in Ireland.

Sean Lyons, Anne Pentecost, Richard S J Tol,

This paper aims to determine emissions polluted directly and indirectly by an average person, for each household type, across a wide range of emissions. There are five household type categories: location, income decile, household composition, size and number of disabled residents. Ireland's Sustainable Development Model (ISus) is used which allows ... Read more >>

J Environ Manage (Journal of environmental management)
[2012, 112:186-198]

Cited: 0 times

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Awaiting autoamputation: a primary management strategy for toe gangrene in diabetic foot disease.

Rami Fikri, Colin D Bicknell, Linda M Bloomfield, Sean P R Lyons, Dunisha G Samarasinghe, Richard G J Gibbs, Jonathan Valabhji,

Diabetes Care (Diabetes care)
[2011, 34(8):e134]

Cited: 9 times

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Irish exceptionalism? Local food environments and dietary quality.

Richard Layte, Janas Harrington, Eithne Sexton, Ivan J Perry, John Cullinan, Sean Lyons,

<h4>Objective</h4>To explore whether distance to and density of food outlets within the local area have an impact on individual dietary quality, controlling for the socioeconomic characteristics of individuals and their households.<h4>Methods</h4>An analysis of the Survey of Lifestyle, Attitudes and Nutrition in Ireland (SLÁN), a two-stage clustered sample of 10,364 individuals ... Read more >>

J Epidemiol Community Health (Journal of epidemiology and community health)
[2011, 65(10):881-888]

Cited: 15 times

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An empirical assessment of generational differences in basic human values.

Sean T Lyons, Linda Duxbury, Christopher Higgins,

This study assessed generational differences in human values as measured by the Schwartz Value Survey. It was proposed that the two most recent generations, Millennials and Generation Xers, would value Self-enhancement and Openness to Change more than the two older generations, Baby Boomers and Matures, while the two older generations ... Read more >>

Psychol Rep (Psychological reports)
[2007, 101(2):339-352]

Cited: 5 times

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Identification of proinflammatory flagellin proteins in supernatants of Vibrio cholerae O1 by proteomics analysis.

Juan Xicohtencatl-Cortés, Sean Lyons, Adriana P Chaparro, Diana R Hernández, Zeus Saldaña, Maria A Ledesma, María A Rendón, Andrew T Gewirtz, Karl E Klose, Jorge A Girón,

The genome of Vibrio cholerae contains five flagellin genes that encode proteins (FlaA-E) of 39-41 kDa with 61-82% identity among them. Although the existing live oral attenuated vaccine strains against cholera are protective in humans, there is an intrinsic residual cytotoxic and inflammatory component associated with these candidate vaccine strains. ... Read more >>

Mol Cell Proteomics (Molecular & cellular proteomics : MCP)
[2006, 5(12):2374-2383]

Cited: 26 times

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Salmonella typhimurium transcytoses flagellin via an SPI2-mediated vesicular transport pathway.

Sean Lyons, Lixin Wang, James E Casanova, Shanthi V Sitaraman, Didier Merlin, Andrew T Gewirtz,

Apical colonization of polarized epithelia by Salmonella typhimurium results in translocation of flagellin to the basolateral membrane domain, thus enabling activation of toll-like receptor 5 (TLR5)-mediated pro-inflammatory gene expression. Such flagellin transcytosis occurred without a change in epithelial permeability to 40 kDa FITC dextran, did not require bacterial motility and ... Read more >>

J Cell Sci (Journal of cell science)
[2004, 117(Pt 24):5771-5780]

Cited: 40 times

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Helicobacter pylori flagellin evades toll-like receptor 5-mediated innate immunity.

Andrew T Gewirtz, Yimin Yu, Uma S Krishna, Dawn A Israel, Sean L Lyons, Richard M Peek,

Helicobacter pylori colonizes the human stomach for decades unless pharmacologically eradicated. We hypothesized that this flagellated pathogen escapes immune clearance, in part, by avoiding detection by the flagellin receptor Toll-like receptor 5 (TLR5). In contrast to other gram-negative microbes, H. pylori did not release flagellin. Furthermore, recombinant H. pylori flagellin ... Read more >>

J Infect Dis (The Journal of infectious diseases)
[2004, 189(10):1914-1920]

Cited: 147 times

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TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via posttranscriptional mechanism.

Yimin Yu, Hui Zeng, Sean Lyons, Adam Carlson, Didier Merlin, Andrew S Neish, Andrew T Gewirtz,

Toll-like receptors (TLRs) activate antimicrobial gene expression in response to detection of specific bacterial products. Relatively little is known about TLR5, the only TLR thought to be preferentially expressed by epithelial cells, beyond that it confers activation of the transcription factor NF-kappaB in a MyD-88 dependent manner in response to ... Read more >>

Am J Physiol Gastrointest Liver Physiol (American journal of physiology. Gastrointestinal and liver physiology)
[2003, 285(2):G282-90]

Cited: 74 times

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The Salmonella typhimurium flagellar basal body protein FliE is required for flagellin production and to induce a proinflammatory response in epithelial cells.

Katharine A Reed, Michael E Hobert, Claire E Kolenda, Kara A Sands, Michelle Rathman, Miriam O'Connor, Sean Lyons, Andrew T Gewirtz, Philippe J Sansonetti, James L Madara,

During apical colonization by Salmonella typhimurium, intestinal epithelial cells orchestrate a proinflammatory response that involves secretion of chemoattractants, predominantly interleukin-8, which coordinate neutrophil trans-epithelial migration at the site of infection. This host-pathogen interaction requires several S. typhimurium genes. To identify novel genes that participate in this pathogen-induced proinflammatory response, we ... Read more >>

J Biol Chem (The Journal of biological chemistry)
[2002, 277(15):13346-13353]

Cited: 44 times

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