Full Text Journal Articles by
Author Scott M Gilbert

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Prevalence of Preoperative Iron Deficiency Anemia: A Case Series Among Patients Undergoing Radical Cystectomy.

Sephalie Y Patel, Timothy E Kubal, Roger Li, Brandon J Manley, Scott M Gilbert, Wade J Sexton, Philippe E Spiess, David Boulware, Michael A Poch,

Anemia occurs in a significant group of patients with bladder cancer before radical cystectomy. Iron deficiency is a readily identifiable cause of anemia, which can be treated before surgery. The proportion of patients with bladder cancer with iron deficiency anemia is unknown. Laboratory and clinical outcomes were collected on 47 ... Read more >>

A A Pract (A&A practice)
[2021, 15(5):e01477]

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Pathologic Downstaging and Survival Outcomes Associated with Neoadjuvant Chemotherapy for Variant Histology Muscle Invasive Bladder Cancer.

Nicholas H Chakiryan, Da David Jiang, Kyle A Gillis, Elizabeth Green, Ali Hajiran, Lee Hugar, Logan Zemp, Jingsong Zhang, Rohit Jain, Jad Chahoud, Michael Poch, Brandon J Manley, Roger Li, Wade Sexton, Scott M Gilbert,

<h4>Purpose</h4>Patients with muscle invasive bladder cancer (MIBC) of variant histology have a poor prognosis. It is unclear if neoadjuvant chemotherapy prior to radical cystectomy is associated with pathologic downstaging or improved overall survival (OS) for patients with variant histology. Our objective was to assess for associations between receipt of neoadjuvant ... Read more >>

J Urol (The Journal of urology)
[2021, :101097JU0000000000001855]

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Preoperative immunonutrition and carbohydrate loading associated with improved bowel function after radical cystectomy.

Sephalie Y Patel, Nathaniel Trona, Brandon Alford, Jose M Laborde, Youngchul Kim, Roger Li, Brandon J Manley, Scott M Gilbert, Wade J Sexton, Philippe E Spiess, Michael A Poch,

<h4>Background</h4>Preoperative malnourishment has been consistently associated with poor outcomes after radical cystectomy and other major abdominal surgeries. Most enhanced recovery after surgery (ERAS) studies have examined preoperative nutrition and its relationship to outcomes after gastrointestinal surgery. Although numerous studies have demonstrated the benefits of using an ERAS protocol, this study ... Read more >>

Nutr Clin Pract (Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition)
[2021, :]

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Real-World Survival Outcomes Associated With First-Line Immunotherapy, Targeted Therapy, and Combination Therapy for Metastatic Clear Cell Renal Cell Carcinoma.

Nicholas H Chakiryan, Da David Jiang, Kyle A Gillis, Elizabeth Green, Ali Hajiran, Lee Hugar, Logan Zemp, Jingsong Zhang, Rohit K Jain, Jad Chahoud, Philippe E Spiess, Wade Sexton, Scott M Gilbert, Brandon J Manley,

<h4>Importance</h4>Clinical trials have shown an overall survival (OS) benefit associated with first-line immunotherapy (IT) and combination targeted therapy (TT) and IT regimens compared with TT among patients with metastatic clear cell renal cell carcinoma (RCC). Generalizability of these findings in a real-world cohort outside of a clinical trial setting is ... Read more >>

JAMA Netw Open (JAMA network open)
[2021, 4(5):e2111329]

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Patient-Reported Outcomes in Clinical Trials Leading to Cancer Immunotherapy Drug Approvals From 2011 to 2018: A Systematic Review.

Houssein Safa, Monica Tamil, Philippe E Spiess, Brandon Manley, Julio Pow-Sang, Scott M Gilbert, Firas Safa, Brian D Gonzalez, Laura B Oswald, Adele Semaan, Adi Diab, Jad Chahoud,

<h4>Background</h4>Patient-reported outcomes (PROs) promote patient centeredness in clinical trials; however, in the field of rapidly emerging and clinically impressive immunotherapy, data on PROs are limited.<h4>Methods</h4>We systematically identified all immunotherapy approvals from 2011 through 2018 and assessed the analytic tools and reporting quality of associated PRO reports. For randomized clinical trials ... Read more >>

J Natl Cancer Inst (Journal of the National Cancer Institute)
[2021, 113(5):532-542]

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Immunotherapy in Bacillus Calmette-Guerin (BCG) unresponsive nonmuscle invasive bladder cancer.

Lee A Hugar, Scott M Gilbert, Wade J Sexton, Ashish M Kamat, Roger Li,

<h4>Purpose of review</h4>A number of promising therapies for Bacillus Calmette-Guerin (BCG) unresponsive nonmuscle invasive bladder cancer (NMIBC) are in the pipeline. In this review, we discuss the history of immunotherapy for the treatment of NMIBC and future developments, focusing on novel intravesical treatments.<h4>Recent findings</h4>The term BCG unresponsive NMIBC encompasses patients ... Read more >>

Curr Opin Urol (Current opinion in urology)
[2021, 31(2):160-169]

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Retroperitoneal Lymph Node Dissection Versus Surveillance for Adult Early Stage Pure Testicular Teratoma: A Nationwide Analysis.

Ali Hajiran, Mounsif Azizi, Ahmet M Aydin, Nicholas H Chakiryan, Charles C Peyton, David C Boulware, Brandon J Manley, Scott M Gilbert, Wade J Sexton,

<h4>Purpose</h4>Following radical orchiectomy, surveillance and primary retroperitoneal lymph node dissection (RPLND) are acceptable options for the management of early stage pure testicular teratoma in adult patients; however, there is no uniform consensus. The aim of this study was to investigate survival outcomes of adults with early stage pure testicular teratoma ... Read more >>

Ann Surg Oncol (Annals of surgical oncology)
[2021, 28(7):3648-3655]

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Reply By Authors.

Ali Hajiran, Mounsif Azizi, Ahmet M Aydin, Logan Zemp, Charles C Peyton, Jasreman Dhillon, Samantha Nealon, Richard R Reich, Biwei Cao, Roger Li, Brandon J Manley, Wade J Sexton, Scott M Gilbert,

J Urol (The Journal of urology)
[2021, 205(1):108]

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Pathological and Survival Outcomes Associated with Variant Histology Bladder Cancers Managed by Cystectomy with or without Neoadjuvant Chemotherapy.

Ali Hajiran, Mounsif Azizi, Ahmet M Aydin, Logan Zemp, Charles C Peyton, Jasreman Dhillon, Samantha Nealon, Richard R Reich, Biwei Cao, Roger Li, Brandon J Manley, Wade J Sexton, Scott M Gilbert,

<h4>Purpose</h4>Although neoadjuvant chemotherapy is associated with a survival advantage in pure urothelial, muscle invasive bladder cancer, the role of neoadjuvant chemotherapy is less clear in variant histology or urothelial carcinoma with divergent differentiation. We compared chemotherapy response and survival outcomes of patients with nonpure urothelial carcinoma histology who were managed ... Read more >>

J Urol (The Journal of urology)
[2021, 205(1):100-108]

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Development and evaluation of a bladder Cancer specific survivorship care plan by patients and clinical care providers: a multi-methods approach.

Cheryl T Lee, Nihal E Mohamed, Sailaja Pisipati, Qainat N Shah, Piyush K Agarwal, Tracy M Downs, Michael Droller, Scott M Gilbert, Heather H Goltz, Simon J Hall, Mohamed Hendawi, Jean Hoffman-Censits, Michael O'Donnell, Matthew Kaag, Lawrence I Karsh, Wassim Kassouf, Diane Z Quale, Arthur Sagalowsky, Gary D Steinberg, David M Latini,

<h4>Background, context and purpose</h4>In spite of the mixed evidence for their impact, survivorship Care Plans (SCPs) are recommended to enhance quality of care for cancer survivors. Data on the feasibility of SCPs in bladder cancer (BC) is sparse. Using a mixed-methods approach, this study describes the iterative development, acceptability and ... Read more >>

BMC Health Serv Res (BMC health services research)
[2020, 20(1):686]

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Focal bipolar radiofrequency ablation for localized prostate cancer: Safety and feasibility.

Ahmet Murat Aydin, Kenneth Gage, Jasreman Dhillon, Salim K Cheriyan, Michael A Poch, Brandon J Manley, Roger Li, Wade J Sexton, Philippe E Spiess, Scott M Gilbert, Julio M Pow-Sang,

<h4>Objectives</h4>To evaluate the safety and feasibility of focal bipolar radiofrequency ablation in men with localized prostate cancer.<h4>Methods</h4>A review of 10 patients treated with a novel bipolar radiofrequency ablation probe integrated in a coil design (Encage; Trod Medical, Bradenton, FL, USA) between 2011 and 2017 in two prospective pilot trials. All ... Read more >>

Int J Urol (International journal of urology : official journal of the Japanese Urological Association)
[2020, 27(10):882-889]

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Innovations in research and clinical care using patient-generated health data.

Heather S L Jim, Aasha I Hoogland, Naomi C Brownstein, Anna Barata, Adam P Dicker, Hans Knoop, Brian D Gonzalez, Randa Perkins, Dana Rollison, Scott M Gilbert, Ronica Nanda, Anders Berglund, Ross Mitchell, Peter A S Johnstone,

Patient-generated health data (PGHD), or health-related data gathered from patients to help address a health concern, are used increasingly in oncology to make regulatory decisions and evaluate quality of care. PGHD include self-reported health and treatment histories, patient-reported outcomes (PROs), and biometric sensor data. Advances in wireless technology, smartphones, and ... Read more >>

CA Cancer J Clin (CA: a cancer journal for clinicians)
[2020, 70(3):182-199]

Cited: 5 times

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Reframing Financial Incentives Around Reducing Readmission After Radical Cystectomy.

Michael S Sessine, Alon Weizer, Peter S Kirk, Tudor Borza, Bruce L Jacobs, Yongmei Qin, Mary Oerline, Benjamin Li, Parth K Modi, Mariel S Lavieri, Scott M Gilbert, Jeffrey S Montgomery, Brent K Hollenbeck, Ken Urish, Jonathan E Helm, Ted A Skolarus,

OBJECTIVE:To better understand the financial implications of readmission after radical cystectomy, an expensive surgery coupled with a high readmission rate. Currently, whether hospitals benefit financially from readmissions after radical cystectomy remains unclear, and potentially obscures incentives to invest in readmission reduction efforts. MATERIALS AND METHODS:Using a 20% sample of national ... Read more >>

Urology (Urology)
[2020, 142:99-105]

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Systematic Review of the Therapeutic Efficacy of Bladder-preserving Treatments for Non-muscle-invasive Bladder Cancer Following Intravesical Bacillus Calmette-Guérin.

Roger Li, Debasish Sundi, Jingsong Zhang, Youngchul Kim, Richard J Sylvester, Philippe E Spiess, Michael A Poch, Wade J Sexton, Peter C Black, James M McKiernan, Gary D Steinberg, Ashish M Kamat, Scott M Gilbert,

<h4>Context</h4>There is a critical need for effective bladder-sparing therapies for bacillus Calmette-Guérin (BCG)-unresponsive non-muscle-invasive bladder cancer (NMIBC). Owing to the current lack of effective agents that can be used as a control, the US Food and Drug Administration began to accept single-arm trials for patients with carcinoma in situ (CIS), ... Read more >>

Eur Urol (European urology)
[2020, 78(3):387-399]

Cited: 3 times

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Urinary leak following partial nephrectomy: a contemporary review of 975 cases.

Charles C Peyton, Ali Hajiran, Kevin Morgan, Mounsif Azizi, Dominic Tang, Juan Chipollini, Scott M Gilbert, Michael Poch, Wade J Sexton, Philippe E Spiess,

<h4>Introduction</h4>To describe the incidence, contemporary management, risk factors and outcomes of urinary leak following open and robotic partial nephrectomy at a tertiary care, comprehensive cancer center.<h4>Materials and methods</h4>We reviewed 975 patients who underwent partial nephrectomy at Moffitt Cancer Center from January 2009 to May 2017. Patient demographic, perioperative and follow ... Read more >>

Can J Urol (The Canadian journal of urology)
[2020, 27(1):10118-10124]

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Focused issue on testicular cancer-forward.

Wade J Sexton, Scott M Gilbert,

Transl Androl Urol (Translational andrology and urology)
[2020, 9(Suppl 1):S1-S2]

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Therapeutic strategies for uncommon testis cancer histologies: teratoma with malignant transformation and malignant testicular sex cord stromal tumors.

Mounsif Azizi, Ahmet M Aydin, Salim K Cheriyan, Charles C Peyton, Matthew Montanarella, Scott M Gilbert, Wade J Sexton,

Testicular cancer is the most common solid malignancy in male adolescents and young adults, with germ cell derived seminomas and non-seminomas being by far the most common histologies. Teratoma with somatic-type malignancy is a rare chemo-resistant phenotype of testis cancer associated with poor prognosis in patients with advanced stage disease. ... Read more >>

Transl Androl Urol (Translational andrology and urology)
[2020, 9(Suppl 1):S91-S103]

Cited: 1 time

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Current management and management controversies in early- and intermediate-stage of nonseminoma germ cell tumors.

Salim K Cheriyan, Marilin Nicholson, Ahmet M Aydin, Mounsif Azizi, Charles C Peyton, Wade J Sexton, Scott M Gilbert,

Early stage nonseminomatous germ cell tumor (NSGCT) remains a treatable disease, with stage I cancer specific survival exceeding 95%. Using a risk-adapted approach; active surveillance (AS), adjuvant chemotherapy, and retroperitoneal lymph node dissection (RPLND) all options for treatment; with surveillance being increasingly used. With persistently elevated markers (stage IS), chemotherapy ... Read more >>

Transl Androl Urol (Translational andrology and urology)
[2020, 9(Suppl 1):S45-S55]

Cited: 1 time

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Primary tumor size thresholds in stage IA testicular seminoma: Implications for adjuvant therapy after orchiectomy and survival.

Mounsif Azizi, Charles C Peyton, David C Boulware, Scott M Gilbert, Wade J Sexton,

<h4>Objectives</h4>Primary tumor size (PTS) is the main prognostic factor for relapse in clinical stage (CS) IA testicular seminoma (T1N0M0S0) and the 8th edition of the Tumor-Node-Metastasis staging system now subcategorizes pT1 tumors into pT1a and pT1b based on PTS (<3 cm and ≥3 cm, respectively). We attempted to assess PTS ... Read more >>

Urol Oncol (Urologic oncology)
[2020, 38(1):7.e9-7.e18]

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Identifying and Codifying Complications after Radical Cystectomy: Comparison of Administrative Diagnostic and Procedure Codes, and Clinical Chart Review.

Charles C Peyton, Richard R Reich, Dominic Tang, Brandon Alford, Mounsif Azizi, Roger Li, Wade J Sexton, Michael Poch, Scott M Gilbert,

<h4>Purpose</h4>To our knowledge the reliability of administrative claims codes to report postoperative radical cystectomy complications has not been examined. We compared complications identified by claims data to those abstracted from clinical chart review following radical cystectomy.<h4>Methods</h4>We manually reviewed the charts of 268 patients treated with radical cystectomy between 2014 and ... Read more >>

J Urol (The Journal of urology)
[2019, 202(5):913-919]

Cited: 1 time

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Optimal Management of High-risk Stage I Nonseminoma Germ Cell Tumor: Active Intervention is the Preferred Option.

Scott M Gilbert, Wade J Sexton,

While there is still debate and uncertainty regarding the best management strategy for clinical stage IB nonseminoma germ cell tumor, adjuvant treatment with chemotherapy or surgery is associated with a markedly lower risk of recurrence for men with high-risk features and provides more definitive disease control and lower overall exposure ... Read more >>

Eur Urol Focus (European urology focus)
[2019, 5(5):704-705]

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Decision Regret Related to Urinary Diversion Choice among Patients Treated with Cystectomy.

Devon K Check, Michael C Leo, Matthew P Banegas, Joanna E Bulkley, Kim N Danforth, Scott M Gilbert, Marilyn L Kwan, Maureen O'Keeffe Rosetti, Carmit K McMullen,

<h4>Purpose</h4>Patients who undergo cystectomy due to bladder cancer can elect an ileal conduit or a neobladder for urinary diversion. Decision regret related to this choice is an important and undesirable patient reported outcome. Our objective was to compare the severity of decision regret experienced by patients with a neobladder vs ... Read more >>

J Urol (The Journal of urology)
[2020, 203(1):159-163]

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Characterising 'bounce-back' readmissions after radical cystectomy.

Peter S Kirk, Ted A Skolarus, Bruce L Jacobs, Yongmei Qin, Benjamin Li, Michael Sessine, Xiang Liu, Kevin Zhu, Scott M Gilbert, Brent K Hollenbeck, Ken Urish, Jonathan Helm, Mariel S Lavieri, Tudor Borza,

<h4>Objective</h4>To examine predictors of early readmissions after radical cystectomy (RC). Factors associated with preventable readmissions may be most evident in readmissions that occur within 3 days of discharge, commonly termed 'bounce-back' readmissions, and identifying such factors may inform efforts to reduce surgical readmissions.<h4>Patients and methods</h4>We utilised the Healthcare Cost and Utilization ... Read more >>

BJU Int (BJU international)
[2019, 124(6):955-961]

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Development of a Goal Elicitation Measure to Support Choice about Urinary Diversion by Patients with Bladder Cancer.

Michael C Leo, Scott M Gilbert, Christopher S Wendel, Robert S Krouse, Marcia Grant, Kim N Danforth, Marilyn L Kwan, Teresa N Harrison, Joanna E Bulkley, Carmit K McMullen,

PURPOSE:Patient centered care aims to align treatment with patient goals, especially when treatment options have equivalent clinical outcomes. For surgeries with lasting impacts that alignment is critical. To our knowledge no psychometrically tested preference elicitation measures exist to support patients with bladder cancer treated with cystectomy, who can often choose ... Read more >>

J Urol (The Journal of urology)
[2019, 202(1):83-89]

Cited: 2 times

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Reply to Yubo Yang, Xin Wei, and Ping Han's Letter to the Editor re: Roger Li, Philippe E. Spiess, Scott M. Gilbert, Andrea Necchi. Towards Personalized Neoadjuvant Therapy for Muscle-invasive Bladder Cancer. Eur Urol 2019;76:4-6.

Roger Li, Philippe E Spiess, Scott M Gilbert, Andrea Necchi,

Eur Urol (European urology)
[2019, 76(2):e34]

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