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Author Scipione Carerj

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Relationship between vascular damage and left ventricular concentric geometry in patients undergoing coronary angiography: a multicenter prospective study.

Massimo Salvetti, Anna Paini, Rita Facchetti, Antonella Moreo, Scipione Carerj, Alessandro Maloberti, Nicola Gaibazzi, Pompilio Faggiano, Gianfranco Mureddu, Fausto Rigo, Cristina Giannattasio, Maria Lorenza Muiesan, ,

BACKGROUND:Vascular structural (intima-media thickness) and functional (carotid pulse wave velocity, cPWV) alterations are related to different patterns of left ventricular (LV) geometry in general population samples and in hypertensive patients. The relationship between vascular damage, evaluated by both echotracking ultrasound and coronary angiography, and LV geometry has not been prospectively ... Read more >>

J. Hypertens. (Journal of hypertension)
[2019, 37(6):1183-1190]

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Takotsubo cardiomyopathy: prognostication is affected by the underlying trigger: the reply.

Maurizio Cusmà-Piccione, Luca Longobardo, Scipione Carerj, Bijoy K Khandheria, Concetta Zito,

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2019, 20(6):410]

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Echocardiographic reference ranges for normal non-invasive myocardial work indices: results from the EACVI NORRE study.

Roberta Manganaro, Stella Marchetta, Raluca Dulgheru, Federica Ilardi, Tadafumi Sugimoto, Sébastien Robinet, Sara Cimino, Yun Yun Go, Anne Bernard, George Kacharava, George D Athanassopoulos, Daniele Barone, Monica Baroni, Nuno Cardim, Andreas Hagendorff, Krasimira Hristova, Teresa López-Fernández, Gonzalo de la Morena, Bogdan A Popescu, Martin Penicka, Tolga Ozyigit, Jose David Rodrigo Carbonero, Nico van de Veire, Ralph Stephan Von Bardeleben, Dragos Vinereanu, Jose Luis Zamorano, Monica Rosca, Andreea Calin, Marie Moonen, Julien Magne, Bernard Cosyns, Elena Galli, Erwan Donal, Scipione Carerj, Concetta Zito, Ciro Santoro, Maurizio Galderisi, Luigi P Badano, Roberto M Lang, Cecile Oury, Patrizio Lancellotti,

AIMS:To obtain the normal ranges for 2D echocardiographic (2DE) indices of myocardial work (MW) from a large group of healthy volunteers over a wide range of ages and gender. METHODS AND RESULTS:A total of 226 (85 men, mean age: 45 ± 13 years) healthy subjects were enrolled at 22 collaborating institutions of the ... Read more >>

Eur Heart J Cardiovasc Imaging (European heart journal cardiovascular Imaging)
[2019, 20(5):582-590]

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Effect of uric acid serum levels on carotid arterial stiffness and intima-media thickness: A high resolution Echo-Tracking Study.

Francesco Antonini-Canterin, Concetta Di Nora, Marco Pellegrinet, Olga Vriz, Salvatore La Carrubba, Scipione Carerj, Concetta Zito, Anca Matescu, Andreea Ravasel, Iulian Cosei, Bogdan A Popescu,

Serum uric acid (UA) has been shown to be a predictor of cardiovascular (CV) morbidity and mortality, and it may play a role in the pathogenesis of CV disease affecting vascular structure and function. However, there is limited evidence of its specific association with carotid artery stiffness and structure. The ... Read more >>

Monaldi Arch Chest Dis (Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace)
[2019, 89(1):]

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Interactive role of diastolic dysfunction and ventricular remodeling in asymptomatic subjects at increased risk of heart failure.

Iacopo Fabiani, Nicola Riccardo Pugliese, Salvatore La Carrubba, Lorenzo Conte, Paolo Colonna, Pio Caso, Frank Benedetto, Francesco Antonini-Canterin, Rodolfo Citro, Frank Lloyd Dini, Scipione Carerj, Vitantonio Di Bello, ,

Diastolic dysfunction (DD) and left ventricular remodeling (LVR) characterize patients at risk for heart failure (HF). To assess the prognostic impact of different diastolic function algorithms and a complex LVR classification (CRC) in asymptomatic subjects with preserved ejection fraction (EF) at risk for HF. We analyzed 1923 asymptomatic patients (male ... Read more >>

Int J Cardiovasc Imaging (The international journal of cardiovascular imaging)
[2019, 35(7):1231-1240]

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Echocardiographic Findings in Cardiac Amyloidosis: Inside Two-Dimensional, Doppler, and Strain Imaging.

Dalia Di Nunzio, Antonino Recupero, Cesare de Gregorio, Concetta Zito, Scipione Carerj, Gianluca Di Bella,

PURPOSE OF REVIEW:The aim is to provide a description of the most important echocardiographic features in systemic amyloidosis. RECENT FINDINGS:Amyloidosis is a heterogeneous group of multisystem disorders, characterized by an extracellular deposition of amyloid fibrils. Several imaging tests are available for the diagnosis; however, echocardiography is the cornerstone of the ... Read more >>

Curr Cardiol Rep (Current cardiology reports)
[2019, 21(2):7]

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Ten Years of 2D Longitudinal Strain for Early Myocardial Dysfunction Detection: A Clinical Overview.

Concetta Zito, Luca Longobardo, Rodolfo Citro, Maurizio Galderisi, Lilia Oreto, Maria Ludovica Carerj, Roberta Manganaro, Maurizio Cusmà-Piccione, Maria Chiara Todaro, Gianluca Di Bella, Egidio Imbalzano, Bijoy K Khandheria, Scipione Carerj,

In recent years, the role of left ventricular ejection fraction (EF) as the gold standard parameter for the evaluation of systolic function has been questioned, and many efforts have been concentrated in the clinical validation of new noninvasive tools for the study of myocardial contractility. Improvement in the accuracy of ... Read more >>

Biomed Res Int (BioMed research international)
[2018, 2018:8979407]

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Takotsubo cardiomyopathy: queries of the current era.

Maurizio Cusmà-Piccione, Luca Longobardo, Alessandra Oteri, Roberta Manganaro, Gianluca Di Bella, Scipione Carerj, Bijoy K Khandheria, Concetta Zito,

: Takotsubo cardiomyopathy (TTS), also known as left ventricular apical ballooning syndrome, is an acute, usually reversible heart failure syndrome that most often affects postmenopausal women experiencing an emotionally stressful event. It is characterized by sudden left ventricular dysfunction and wall motion abnormalities involving the apical and mid segments. TTS ... Read more >>

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2018, 19(11):624-632]

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Multimodality imaging for thromboembolic risk assessment in atrial fibrillation.

Maria C Todaro, Antonio Solazzo, Gaetano Senatore, Concetta Zito, Gianluca Di Bella, Maria L Carerj, Giuseppe Oreto, Scipione Carerj,

: Atrial fibrillation is the most widely represented sustained arrhythmia in the world. Thromboembolic risk assessment represents the main clinical challenge associated with this condition, requiring enormous medical, social and economical efforts. Several pieces of evidence in literature highlight how clinical risk factors are not enough for a correct thromboembolic ... Read more >>

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2018, 19(12):698-705]

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Value of ejection fraction/velocity ratio in the prognostic stratification of patients with asymptomatic aortic valve stenosis.

Francesco Antonini-Canterin, Concetta Di Nora, Eugenio Cervesato, Concetta Zito, Scipione Carerj, Andreea Ravasel, Iulian Cosei, Andreea Catarina Popescu, Bogdan Alexandru Popescu,

BACKGROUND:The ejection fraction/velocity ratio (EFVR) is a simple function-corrected index of aortic stenosis severity with a good correlation with aortic valve area measured using the Gorlin formula at cardiac catheterization. It is calculated by dividing left ventricular ejection fraction (LVEF) to 4 × (peak jet velocity)2 . OBJECTIVE:Our aim was to evaluate ... Read more >>

Echocardiography (Echocardiography (Mount Kisco, N.Y.))
[2018, 35(12):1909-1914]

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Arterial stiffness and mitral regurgitation in arterial hypertension: an intriguing pathophysiological link.

Egidio Imbalzano, Marco Vatrano, Lorenzo Ghiadoni, Giuseppe Mandraffino, Andrea Dalbeni, Bijoy K Khandheria, Rossella Costantino, Giovanni Trapani, Roberta Manganaro, Maurizio Cusmà Piccione, Scipione Carerj, Roberto Ceravolo, Antonino Saitta, Concetta Zito,

BACKGROUND:We examined the relative impact of arterial stiffness on the presence and/or severity of chronic mitral regurgitation (MR) in hypertensive patients. METHODS:We prospectively enrolled 141 untreated hypertensive patients (mean age 56.6 ± 11.5 years): 94 with MR, 47 without MR. As a measure of arterial stiffness, pulse wave velocity (PWV) was assessed by ... Read more >>

Vascul. Pharmacol. (Vascular pharmacology)
[2018, 111:71-76]

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Left ventricular endocardial longitudinal dysfunction persists after acute myocarditis with preserved ejection fraction.

Gianluca Di Bella, Scipione Carerj, Antonino Recupero, Rocco Donato, Pietro Pugliatti, Gabriella Falanga, Stefano Pedri, Giampiero Vizzari, Mariapaola Campisi, Concetta Zito, Cesare de Gregorio,

BACKGROUND:The aim of present study was to assess left ventricular (LV) myocardial deformation and changes over time in patients with acute myocarditis (AM) with preserved ejection fraction detected by late gadolinium enhancement (LGE) magnetic resonance imaging. METHODS:Thirty-five male patients with AM diagnoses and preserved systolic function based on cardiac magnetic ... Read more >>

Echocardiography (Echocardiography (Mount Kisco, N.Y.))
[2018, 35(12):1966-1973]

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Role of Echocardiography in Assessment of Cardioembolic Sources: a Strong Diagnostic Resource in Patients with Ischemic Stroke.

Luca Longobardo, Concetta Zito, Scipione Carerj, Giuseppe Caracciolo, Matt Umland, Bijoy K Khandheria,

PURPOSE OF REVIEW:This review will discuss the most frequent sources of cardiac embolism and the role of echocardiography in these different clinical settings, and, in addition, provide suggestions about the choice between transthoracic (TTE) and transesophageal echocardiography (TEE). RECENT FINDINGS:Stroke is the third leading cause of death in industrial countries, ... Read more >>

Curr Cardiol Rep (Current cardiology reports)
[2018, 20(12):136]

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Diastolic dysfunction evaluated by cardiac magnetic resonance: the value of the combined assessment of atrial and ventricular function.

Giovanni Donato Aquaro, Fausto Pizzino, Anna Terrizzi, Scipione Carerj, Bijoy K Khandheria, Gianluca Di Bella,

OBJECTIVES:We sought to evaluate the role of cardiac magnetic resonance imaging (CMR) in the evaluation of diastolic function by a combined assessment of left ventricular (LV) and left atrial (LA) function in a cohort of subjects with various degrees of diastolic dysfunction (DD) detected by echocardiography. METHODS:Forty patients with different ... Read more >>

Eur Radiol (European radiology)
[2019, 29(3):1555-1564]

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Impairment of elastic properties of the aorta in bicuspid aortic valve: relationship between biomolecular and aortic strain patterns.

Luca Longobardo, Maria Ludovica Carerj, Gabriele Pizzino, Alessandra Bitto, Maurizio Cusma Piccione, Marta Zucco, Lilia Oreto, Maria Chiara Todaro, Maria Pia Calabrò, Francesco Squadrito, Gianluca Di Bella, Giuseppe Oreto, Bijoy K Khandheria, Scipione Carerj, Concetta Zito,

Aims:Bicuspid aortic valve (BAV) is associated with aortic wall alterations. We aimed to detect any correlation between aortic elasticity and genetic and biomolecular patterns of elastin. Methods and results:Forty-nine BAV patients (mean age: 38 ± 17.05) were prospectively enrolled. A blood sample was drawn for analysis of a single nucleotide polymorphism of ... Read more >>

Eur Heart J Cardiovasc Imaging (European heart journal cardiovascular Imaging)
[2018, 19(8):879-887]

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New classification of geometric ventricular patterns in severe aortic stenosis: Could it be clinically useful?

Concetta Di Nora, Eugenio Cervesato, Iulian Cosei, Andreea Ravasel, Bogdan A Popescu, Concetta Zito, Scipione Carerj, Francesco Antonini-Canterin, Andreea C Popescu,

BACKGROUND:In severe aortic stenosis, different left ventricle (LV) remodeling patterns as a response to pressure overload have distinct hemodynamic profiles, cardiac function, and outcomes. The most common classification considers LV relative wall thickness and LV mass index to create 4 different groups. A new classification including also end-diastolic volume index ... Read more >>

Echocardiography (Echocardiography (Mount Kisco, N.Y.))
[2018, 35(8):1077-1084]

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Bicuspid Aortic Valve Registry of the Italian Society of Echocardiography and Cardiovascular Imaging (REgistro della valvola aortica bicuspide della società italiana di ECocardiografia e CArdiovascular imaging): Rationale and Study Design.

Rodolfo Citro, Moreno Cecconi, Salvatore La Carrubba, Eduardo Bossone, Francesco Antonini-Canterin, Stefano Nistri, Fabio Chirillo, Ilaria Dentamaro, Michele Bellino, Alfredo Posteraro, Mauro Giorgi, Licia Petrella, Ines Monte, Vincenzo Manuppelli, Antonio Mantero, Scipione Carerj, Frank Benedetto, Paolo Colonna,

Bicuspid aortic valve (BAV) is the most common congenital heart disease, affecting 0.5%-2% of the general population. It is associated not only with notable valvular risk (aortic stenosis and/or regurgitation, endocarditis) but also with aortopathy with a wide spectrum of unpredictable clinical presentations, including aneurysmal dilation of the aortic root ... Read more >>

J Cardiovasc Echogr (Journal of cardiovascular echography)
[2018, 28(2):78-89]

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Prognostic Value of a Tissue Doppler Index of Systodiastolic Function in Patients with Asymptomatic Heart Failure.

Nicola Riccardo Pugliese, Iacopo Fabiani, Salvatore La Carrubba, Scipione Carerj, Lorenzo Conte, Paolo Colonna, Pio Caso, Frank Benedetto, Francesco Antonini-Canterin, Maria Francesca Romano, Rodolfo Citro, Vitantonio Di Bello, ,

Doppler echocardiography with early diastolic transmitral velocity (E)/early mitral annular diastolic velocity (E') ratio has been proposed as the best predictor for evaluating left ventricle (LV) filling pressure. A dimensionless index E/(E' × S') ratio (S' = systolic mitral annulus velocity) resulted in readily, reproducible, and reliable predictor of LV ... Read more >>

J Cardiovasc Echogr (Journal of cardiovascular echography)
[2018, 28(2):95-100]

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Cardiovascular Multimodality Imaging: It is Time to Get on Board! A "Società Italiana di Ecocardiografia e CardioVascular Imaging" Statement.

Francesco Antonini-Canterin, Giorgio Faganello, Antonio Mantero, Rodolfo Citro, Paolo Colonna, Mauro Giorgi, Vincenzo Manuppelli, Ines Monte, Licia Petrella, Alfredo Posteraro, Vitantonio Di Bello, Scipione Carerj, Frank Benedetto,

J Cardiovasc Echogr (Journal of cardiovascular echography)
[2018, 28(1):1-8]

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Atrial septal defect morphology and stenting in hypoplastic left heart syndrome after hybrid palliation.

Lilia Oreto, Giuseppe Mandraffino, Lucia Manuri, Michele B Saitta, Salvatore Agati, Concetta Zito, Fiore S Iorio, Scipione Carerj, Paolo Guccione,

Aims The aim of this study was to describe atrial septal defect morphology in hypoplastic left heart syndrome, to report the incidence of restrictiveness and its relationship with defect morphology, to correlate restriction with midterm outcome, and to describe our interventional approach to restrictive defect. Methods and results From 2011 ... Read more >>

Cardiol Young (Cardiology in the young)
[2018, 28(2):252-260]

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Detection of myocardial iron overload by two-dimensional speckle tracking in patients with beta-thalassaemia major: a combined echocardiographic and T2* segmental CMR study.

Fausto Pizzino, Antonella Meloni, Anna Terrizzi, Tommaso Casini, Anna Spasiano, Carlo Cosmi, Massimo Allò, Concetta Zito, Scipione Carerj, Giovanni Donato Aquaro, Gianluca Di Bella, Alessia Pepe,

We aimed to evaluate the role of two-dimensional speckle tracking imaging (2DSTI) in detecting early changes of myocardial deformation in patients affected by thalassemia major (TM) and its relation with myocardial iron overload (MIO) detected by T2* cardiovascular magnetic resonance (CMR). We studied 28 TM patients (15 males, 37.4 ± 10 years). All ... Read more >>

Int J Cardiovasc Imaging (The international journal of cardiovascular imaging)
[2018, 34(2):263-271]

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Role of Two-Dimensional Speckle-Tracking Echocardiography Strain in the Assessment of Right Ventricular Systolic Function and Comparison with Conventional Parameters.

Luca Longobardo, Valentin Suma, Renuka Jain, Scipione Carerj, Concetta Zito, Dianne L Zwicke, Bijoy K Khandheria,

Despite the already well-known role the right side of the heart plays in many diseases, right ventricular (RV) function has only recently been carefully considered. Echocardiography is the first-line diagnostic technique for the assessment of the right ventricle and right atrium, whereas cardiac magnetic resonance is considered the gold standard ... Read more >>

J Am Soc Echocardiogr (Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography)
[2017, 30(10):937-946.e6]

Cited: 4 times

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Left atrium in heart failure with preserved ejection fraction: the importance of function before anatomy.

Luca Longobardo, Concetta Zito, Scipione Carerj, Bijoy K Khandheria,

Eur Heart J Cardiovasc Imaging (European heart journal cardiovascular Imaging)
[2017, 18(7):730-731]

Cited: 1 time

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High-risk patients with mild-moderate left ventricular dysfunction after a previous myocardial infarction. A long-term prognostic data by cardiac magnetic resonance.

Gianluca Di Bella, Fausto Pizzino, Giovanni Donato Aquaro, Paolo Piaggi, Giuseppe Venuti, Scipione Carerj, Alessandro Pingitore,

Few studies have explored prognosis in patients with previous myocardial infarction (MI) with mild-moderate (MM) left ventricular (LV) dysfunction (D). The aim of our study was to investigate whether combining LV parameters obtained by cardiac magnetic resonance (CMR) improves risk stratification of patients with previous MI and MM-LV-D.In 418 consecutive ... Read more >>

Int. J. Cardiol. (International journal of cardiology)
[2017, 245:13-19]

Cited: 1 time

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The Reply.

Luca Longobardo, Renuka Jain, Scipione Carerj, Concetta Zito, Bijoy K Khandheria,

Am. J. Med. (The American journal of medicine)
[2017, 130(7):e317]

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