Full Text Journal Articles by
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A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response.

Yang Luo, Masahiro Kanai, Wanson Choi, Xinyi Li, Saori Sakaue, Kenichi Yamamoto, Kotaro Ogawa, Maria Gutierrez-Arcelus, Peter K Gregersen, Philip E Stuart, James T Elder, Lukas Forer, Sebastian Schönherr, Christian Fuchsberger, Albert V Smith, Jacques Fellay, Mary Carrington, David W Haas, Xiuqing Guo, Nicholette D Palmer, Yii-Der Ida Chen, Jerome I Rotter, Kent D Taylor, Stephen S Rich, Adolfo Correa, James G Wilson, Sekar Kathiresan, Michael H Cho, Andres Metspalu, Tonu Esko, Yukinori Okada, Buhm Han, , Paul J McLaren, Soumya Raychaudhuri,

Fine-mapping to plausible causal variation may be more effective in multi-ancestry cohorts, particularly in the MHC, which has population-specific structure. To enable such studies, we constructed a large (n = 21,546) HLA reference panel spanning five global populations based on whole-genome sequences. Despite population-specific long-range haplotypes, we demonstrated accurate imputation at G-group ... Read more >>

Nat Genet (Nature genetics)
[2021, 53(10):1504-1516]

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Targeting the stress response in pediatric pain: current evidence for psychosocial intervention and avenues for future investigation.

Sarah Nelson, David Borsook, Michelle Bosquet Enlow,

Nonpharmacological treatments for chronic pain in youth have been identified as first-line treatments over and above medication. Therapies such as cognitive-behavioral therapy and mindfulness-based stress reduction have shown good efficacy in reducing the psychological correlates (eg, anxiety, depression, and stress) and social or behavioral sequelae (eg, limited physical activity and ... Read more >>

Pain Rep (Pain reports)
[2021, 6(3):e953]

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You Can't Make Me Stay Home!: Medical & Legal Aspects of the COVID-19 Pandemic.

Sarah E Nelson, Emily J Nelson,

Am J Med (The American journal of medicine)
[2021, :]

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Evaluating the Computerized Assessment and Referral System (CARS) Screener: Sensitivity and Specificity as a Screening Tool for Mental Health Disorders among DUI Offenders.

Sarah E Nelson, Alex LaRaja, Jamie Juviler, Pat M Williams,

<i>Background/Purpose:</i> A growing body of evidence suggests that people who are arrested for driving under the influence (DUI) of alcohol are more likely to screen positive for psychiatric disorders than the general population. Additionally, psychiatric comorbidity has been shown to increase vulnerability to criminal re-offense. However, DUI programs face many ... Read more >>

Subst Use Misuse (Substance use & misuse)
[2021, 56(12):1785-1796]

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Biomarkers of Allostatic Load as Correlates of Impairment in Youth with Chronic Pain: An Initial Investigation.

Sarah Nelson, Samantha Bento, Michelle Bosquet Enlow,

Pediatric chronic pain is common and responsible for significant healthcare burden. However, the mechanisms underlying the development and/or maintenance of pediatric chronic pain remain poorly understood. Allostatic load (AL), or wear and tear on the nervous system following significant or prolonged stress, has been proposed to play a role in ... Read more >>

Children (Basel) (Children (Basel, Switzerland))
[2021, 8(8):]

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Using “Markers of Harm” to Track Risky Gambling in Two Cohorts of Online Sports Bettors

William H.B. McAuliffe, Eric Louderback, Timothy Edson, Debi LaPlante, Sarah Nelson,

<p>Online gambling poses novel risks for problem gambling, but also unique opportunities to detect and intervene with at-risk users. A consortium of gambling companies recently committed to using nine behavioral "Markers of Harm'' that can be calculated with online user data to estimate risk for gambling-related harm. The current study ... Read more >>

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Recommendations for improving adolescent addiction recovery support in six northwest tribal communities.

Martina M Whelshula, Debi A LaPlante, Sarah E Nelson, Heather M Gray,

American Indian and Alaska Native (AI/AN) communities offer tangible and intangible resources, including centuries of indigenous wisdom and resiliency, to support their young people in recovery from substance use disorders. At the same time, tribal youth returning home from residential or inpatient treatment are vulnerable to relapse, especially if they ... Read more >>

J Community Psychol (Journal of community psychology)
[2021, 49(7):2922-2937]

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IDEO energy-storing orthosis: Effects on lower extremity function and preservation.

Benjamin W Hoyt, Sarah Y Nelson, Jeffrey G Fay, Sean M Wade, Daniel I Brooks, Benjamin K Potter,

<h4>Introduction</h4>The Intrepid Dynamic Exoskeletal Orthosis (IDEO) brace is a custom energy-storing orthosis design meant to improve gait, stability, and function after lower extremity injury or limb salvage. Early studies demonstrated the potential for the IDEO to improve functional performance, in conjunction with its paired return to run (RTR) rehabilitation program, ... Read more >>

Injury (Injury)
[2021, :]

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Treatment of Subarachnoid Hemorrhage-associated Delayed Cerebral Ischemia With Milrinone: A Review and Proposal.

Thomas D Bernier, Michael J Schontz, Saef Izzy, David Y Chung, Sarah E Nelson, Thabele M Leslie-Mazwi, Galen V Henderson, Hormuzdiyar Dasenbrock, Nirav Patel, Mohammad A Aziz-Sultan, Steven Feske, Rose Du, Yasser B Abulhasan, Mark R Angle,

Delayed cerebral ischemia (DCI) following aneurysmal subarachnoid hemorrhage continues to be associated with high levels of morbidity and mortality. This complication had long been thought to occur secondary to severe cerebral vasospasm, but expert opinion now favors a multifactorial etiology, opening the possibility of new therapies. To date, no definitive ... Read more >>

J Neurosurg Anesthesiol (Journal of neurosurgical anesthesiology)
[2021, 33(3):195-202]

Cited: 2 times

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Changes to the playing field: A contemporary study of actual European online sports betting.

Sarah E Nelson, Timothy C Edson, Eric R Louderback, Matthew A Tom, Alessandra Grossman, Debi A LaPlante,

<h4>Background and aims</h4>Online sports wagering is a popular and still growing gambling activity around the world. Like other types of gambling, it can lead to problems that include devastating financial, social, and health-related harms. The first analysis of actual online sports wagering activity (LaBrie et al., 2007) suggested that levels ... Read more >>

J Behav Addict (Journal of behavioral addictions)
[2021, :]

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Influenza Vaccination of Swine Reduces Public Health Risk at the Swine-Human Interface.

Joshua N Lorbach, Sarah W Nelson, Sarah E Lauterbach, Jacqueline M Nolting, Eben Kenah, Dillon S McBride, Marie R Culhane, Christa Goodell, Andrew S Bowman,

Influenza A viruses (IAV) in swine (IAV-S) pose serious risk to public health through spillover at the human-animal interface. Continued zoonotic transmission increases the likelihood novel IAV-S capable of causing the next influenza pandemic will emerge from this animal reservoir. Because current mitigation strategies are insufficient to prevent IAV zoonosis, ... Read more >>

mSphere (mSphere)
[2021, :e0117020]

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Assessment of gender differences in letters of recommendation for pharmacy residency applicants.

Mikhaila L Rice, Jonathan G Leung, Kristin C Mara, Sarah B Leung,

<h4>Purpose</h4>Letters of recommendation (LORs) are highly regarded components of pharmacy residency applications, as they provide insight into an applicant's character and capabilities. In other medical fields, differences in language have been reported for letters written for female and male applicants; however, data on gender differences in LORs for pharmacy residency ... Read more >>

Am J Health Syst Pharm (American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists)
[2021, 78(12):1118-1125]

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Variant-specific inflation factors for assessing population stratification at the phenotypic variance level.

Tamar Sofer, Xiuwen Zheng, Cecelia A Laurie, Stephanie M Gogarten, Jennifer A Brody, Matthew P Conomos, Joshua C Bis, Timothy A Thornton, Adam Szpiro, Jeffrey R O'Connell, Ethan M Lange, Yan Gao, L Adrienne Cupples, Bruce M Psaty, , Kenneth M Rice,

In modern Whole Genome Sequencing (WGS) epidemiological studies, participant-level data from multiple studies are often pooled and results are obtained from a single analysis. We consider the impact of differential phenotype variances by study, which we term 'variance stratification'. Unaccounted for, variance stratification can lead to both decreased statistical power, ... Read more >>

Nat Commun (Nature communications)
[2021, 12(1):3506]

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Genome sequencing unveils a regulatory landscape of platelet reactivity.

Ali R Keramati, Ming-Huei Chen, Benjamin A T Rodriguez, Lisa R Yanek, Arunoday Bhan, Brady J Gaynor, Kathleen Ryan, Jennifer A Brody, Xue Zhong, Qiang Wei, , Kai Kammers, Kanika Kanchan, Kruthika Iyer, Madeline H Kowalski, Achilleas N Pitsillides, L Adrienne Cupples, Bingshan Li, Thorsten M Schlaeger, Alan R Shuldiner, Jeffrey R O'Connell, Ingo Ruczinski, Braxton D Mitchell, Nauder Faraday, Margaret A Taub, Lewis C Becker, Joshua P Lewis, Rasika A Mathias, Andrew D Johnson,

Platelet aggregation at the site of atherosclerotic vascular injury is the underlying pathophysiology of myocardial infarction and stroke. To build upon prior GWAS, here we report on 16 loci identified through a whole genome sequencing (WGS) approach in 3,855 NHLBI Trans-Omics for Precision Medicine (TOPMed) participants deeply phenotyped for platelet ... Read more >>

Nat Commun (Nature communications)
[2021, 12(1):3626]

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The trans-ancestral genomic architecture of glycemic traits.

Ji Chen, Cassandra N Spracklen, Gaëlle Marenne, Arushi Varshney, Laura J Corbin, Jian'an Luan, Sara M Willems, Ying Wu, Xiaoshuai Zhang, Momoko Horikoshi, Thibaud S Boutin, Reedik Mägi, Johannes Waage, Ruifang Li-Gao, Kei Hang Katie Chan, Jie Yao, Mila D Anasanti, Audrey Y Chu, Annique Claringbould, Jani Heikkinen, Jaeyoung Hong, Jouke-Jan Hottenga, Shaofeng Huo, Marika A Kaakinen, Tin Louie, Winfried März, Hortensia Moreno-Macias, Anne Ndungu, Sarah C Nelson, Ilja M Nolte, Kari E North, Chelsea K Raulerson, Debashree Ray, Rebecca Rohde, Denis Rybin, Claudia Schurmann, Xueling Sim, Lorraine Southam, Isobel D Stewart, Carol A Wang, Yujie Wang, Peitao Wu, Weihua Zhang, Tarunveer S Ahluwalia, Emil V R Appel, Lawrence F Bielak, Jennifer A Brody, Noël P Burtt, Claudia P Cabrera, Brian E Cade, Jin Fang Chai, Xiaoran Chai, Li-Ching Chang, Chien-Hsiun Chen, Brian H Chen, Kumaraswamy Naidu Chitrala, Yen-Feng Chiu, Hugoline G de Haan, Graciela E Delgado, Ayse Demirkan, Qing Duan, Jorgen Engmann, Segun A Fatumo, Javier Gayán, Franco Giulianini, Jung Ho Gong, Stefan Gustafsson, Yang Hai, Fernando P Hartwig, Jing He, Yoriko Heianza, Tao Huang, Alicia Huerta-Chagoya, Mi Yeong Hwang, Richard A Jensen, Takahisa Kawaguchi, Katherine A Kentistou, Young Jin Kim, Marcus E Kleber, Ishminder K Kooner, Shuiqing Lai, Leslie A Lange, Carl D Langefeld, Marie Lauzon, Man Li, Symen Ligthart, Jun Liu, Marie Loh, Jirong Long, Valeriya Lyssenko, Massimo Mangino, Carola Marzi, May E Montasser, Abhishek Nag, Masahiro Nakatochi, Damia Noce, Raymond Noordam, Giorgio Pistis, Michael Preuss, Laura Raffield, Laura J Rasmussen-Torvik, Stephen S Rich, Neil R Robertson, Rico Rueedi, Kathleen Ryan, Serena Sanna, Richa Saxena, Katharina E Schraut, Bengt Sennblad, Kazuya Setoh, Albert V Smith, Thomas Sparsø, Rona J Strawbridge, Fumihiko Takeuchi, Jingyi Tan, Stella Trompet, Erik van den Akker, Peter J van der Most, Niek Verweij, Mandy Vogel, Heming Wang, Chaolong Wang, Nan Wang, Helen R Warren, Wanqing Wen, Tom Wilsgaard, Andrew Wong, Andrew R Wood, Tian Xie, Mohammad Hadi Zafarmand, Jing-Hua Zhao, Wei Zhao, Najaf Amin, Zorayr Arzumanyan, Arne Astrup, Stephan J L Bakker, Damiano Baldassarre, Marian Beekman, Richard N Bergman, Alain Bertoni, Matthias Blüher, Lori L Bonnycastle, Stefan R Bornstein, Donald W Bowden, Qiuyin Cai, Archie Campbell, Harry Campbell, Yi Cheng Chang, Eco J C de Geus, Abbas Dehghan, Shufa Du, Gudny Eiriksdottir, Aliki Eleni Farmaki, Mattias Frånberg, Christian Fuchsberger, Yutang Gao, Anette P Gjesing, Anuj Goel, Sohee Han, Catharina A Hartman, Christian Herder, Andrew A Hicks, Chang-Hsun Hsieh, Willa A Hsueh, Sahoko Ichihara, Michiya Igase, M Arfan Ikram, W Craig Johnson, Marit E Jørgensen, Peter K Joshi, Rita R Kalyani, Fouad R Kandeel, Tomohiro Katsuya, Chiea Chuen Khor, Wieland Kiess, Ivana Kolcic, Teemu Kuulasmaa, Johanna Kuusisto, Kristi Läll, Kelvin Lam, Deborah A Lawlor, Nanette R Lee, Rozenn N Lemaitre, Honglan Li, , Shih-Yi Lin, Jaana Lindström, Allan Linneberg, Jianjun Liu, Carlos Lorenzo, Tatsuaki Matsubara, Fumihiko Matsuda, Geltrude Mingrone, Simon Mooijaart, Sanghoon Moon, Toru Nabika, Girish N Nadkarni, Jerry L Nadler, Mari Nelis, Matt J Neville, Jill M Norris, Yasumasa Ohyagi, Annette Peters, Patricia A Peyser, Ozren Polasek, Qibin Qi, Dennis Raven, Dermot F Reilly, Alex Reiner, Fernando Rivideneira, Kathryn Roll, Igor Rudan, Charumathi Sabanayagam, Kevin Sandow, Naveed Sattar, Annette Schürmann, Jinxiu Shi, Heather M Stringham, Kent D Taylor, Tanya M Teslovich, Betina Thuesen, Paul R H J Timmers, Elena Tremoli, Michael Y Tsai, Andre Uitterlinden, Rob M van Dam, Diana van Heemst, Astrid van Hylckama Vlieg, Jana V van Vliet-Ostaptchouk, Jagadish Vangipurapu, Henrik Vestergaard, Tao Wang, Ko Willems van Dijk, Tatijana Zemunik, Gonçalo R Abecasis, Linda S Adair, Carlos Alberto Aguilar-Salinas, Marta E Alarcón-Riquelme, Ping An, Larissa Aviles-Santa, Diane M Becker, Lawrence J Beilin, Sven Bergmann, Hans Bisgaard, Corri Black, Michael Boehnke, Eric Boerwinkle, Bernhard O Böhm, Klaus Bønnelykke, D I Boomsma, Erwin P Bottinger, Thomas A Buchanan, Mickaël Canouil, Mark J Caulfield, John C Chambers, Daniel I Chasman, Yii-Der Ida Chen, Ching-Yu Cheng, Francis S Collins, Adolfo Correa, Francesco Cucca, H Janaka de Silva, George Dedoussis, Sölve Elmståhl, Michele K Evans, Ele Ferrannini, Luigi Ferrucci, Jose C Florez, Paul W Franks, Timothy M Frayling, Philippe Froguel, Bruna Gigante, Mark O Goodarzi, Penny Gordon-Larsen, Harald Grallert, Niels Grarup, Sameline Grimsgaard, Leif Groop, Vilmundur Gudnason, Xiuqing Guo, Anders Hamsten, Torben Hansen, Caroline Hayward, Susan R Heckbert, Bernardo L Horta, Wei Huang, Erik Ingelsson, Pankow S James, Marjo-Ritta Jarvelin, Jost B Jonas, J Wouter Jukema, Pontiano Kaleebu, Robert Kaplan, Sharon L R Kardia, Norihiro Kato, Sirkka M Keinanen-Kiukaanniemi, Bong-Jo Kim, Mika Kivimaki, Heikki A Koistinen, Jaspal S Kooner, Antje Körner, Peter Kovacs, Diana Kuh, Meena Kumari, Zoltan Kutalik, Markku Laakso, Timo A Lakka, Lenore J Launer, Karin Leander, Huaixing Li, Xu Lin, Lars Lind, Cecilia Lindgren, Simin Liu, Ruth J F Loos, Patrik K E Magnusson, Anubha Mahajan, Andres Metspalu, Dennis O Mook-Kanamori, Trevor A Mori, Patricia B Munroe, Inger Njølstad, Jeffrey R O'Connell, Albertine J Oldehinkel, Ken K Ong, Sandosh Padmanabhan, Colin N A Palmer, Nicholette D Palmer, Oluf Pedersen, Craig E Pennell, David J Porteous, Peter P Pramstaller, Michael A Province, Bruce M Psaty, Lu Qi, Leslie J Raffel, Rainer Rauramaa, Susan Redline, Paul M Ridker, Frits R Rosendaal, Timo E Saaristo, Manjinder Sandhu, Jouko Saramies, Neil Schneiderman, Peter Schwarz, Laura J Scott, Elizabeth Selvin, Peter Sever, Xiao-Ou Shu, P Eline Slagboom, Kerrin S Small, Blair H Smith, Harold Snieder, Tamar Sofer, Thorkild I A Sørensen, Tim D Spector, Alice Stanton, Claire J Steves, Michael Stumvoll, Liang Sun, Yasuharu Tabara, E Shyong Tai, Nicholas J Timpson, Anke Tönjes, Jaakko Tuomilehto, Teresa Tusie, Matti Uusitupa, Pim van der Harst, Cornelia van Duijn, Veronique Vitart, Peter Vollenweider, Tanja G M Vrijkotte, Lynne E Wagenknecht, Mark Walker, Ya X Wang, Nick J Wareham, Richard M Watanabe, Hugh Watkins, Wen B Wei, Ananda R Wickremasinghe, Gonneke Willemsen, James F Wilson, Tien-Yin Wong, Jer-Yuarn Wu, Anny H Xiang, Lisa R Yanek, Loïc Yengo, Mitsuhiro Yokota, Eleftheria Zeggini, Wei Zheng, Alan B Zonderman, Jerome I Rotter, Anna L Gloyn, Mark I McCarthy, Josée Dupuis, James B Meigs, Robert A Scott, Inga Prokopenko, Aaron Leong, Ching-Ti Liu, Stephen C J Parker, Karen L Mohlke, Claudia Langenberg, Eleanor Wheeler, Andrew P Morris, Inês Barroso, ,

Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health. To date, most genetic studies of glycemic traits have focused on individuals of European ancestry. Here we aggregated genome-wide association studies comprising up to 281,416 individuals without diabetes (30% non-European ancestry) for whom fasting glucose, 2-h ... Read more >>

Nat Genet (Nature genetics)
[2021, 53(6):840-860]

Cited: 3 times

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Age-Friendly Cities and Older Indigenous People: An Exploratory Study in Prince George, Canada.

Sarah E Nelson, Mark W Rosenberg,

Cities around the world are responding to aging populations and equity concerns for older people by developing age-friendly communities plans, following the World Health Organization's guidelines. Such plans, however, often fail to account for the wide diversity of older people in cities, with the result that some older people, including ... Read more >>

Can J Aging (Canadian journal on aging = La revue canadienne du vieillissement)
[2021, :1-10]

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Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium.

Silva Kasela, Victor E Ortega, Molly Martorella, Suresh Garudadri, Jenna Nguyen, Elizabeth Ampleford, Anu Pasanen, Srilaxmi Nerella, Kristina L Buschur, Igor Z Barjaktarevic, R Graham Barr, Eugene R Bleecker, Russell P Bowler, Alejandro P Comellas, Christopher B Cooper, David J Couper, Gerard J Criner, Jeffrey L Curtis, MeiLan K Han, Nadia N Hansel, Eric A Hoffman, Robert J Kaner, Jerry A Krishnan, Fernando J Martinez, Merry-Lynn N McDonald, Deborah A Meyers, Robert Paine, Stephen P Peters, Mario Castro, Loren C Denlinger, Serpil C Erzurum, John V Fahy, Elliot Israel, Nizar N Jarjour, Bruce D Levy, Xingnan Li, Wendy C Moore, Sally E Wenzel, Joe Zein, , , Charles Langelier, Prescott G Woodruff, Tuuli Lappalainen, Stephanie A Christenson,

<h4>Background</h4>The large airway epithelial barrier provides one of the first lines of defense against respiratory viruses, including SARS-CoV-2 that causes COVID-19. Substantial inter-individual variability in individual disease courses is hypothesized to be partially mediated by the differential regulation of the genes that interact with the SARS-CoV-2 virus or are involved ... Read more >>

Genome Med (Genome medicine)
[2021, 13(1):66]

Cited: 1 time

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Repair of a Crossbow Bolt Injury of the Subclavian Artery Behind the Mid-clavicle.

Lauren Bruce, Sarah Nelson, Joceline Vu, Amanda P Bettencourt, Gary A Vercruysse,

The management of a rare midclavicular crossbow bolt injury to the subclavian artery is discussed. Important concepts include the initial clinical diagnosis, operative planning, the surgical approach to the retro-clavicular great vessels, the technical aspects of repair, and postoperative course. A discussion of the reasoning behind an operative vs. endovascular ... Read more >>

Am Surg (The American surgeon)
[2021, :31348211003069]

Cited: 0 times

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Adverse Childhood Experiences (ACEs) and Internalizing Mental Health, Pain, and Quality of Life in Youth With Chronic Pain: A Longitudinal Examination.

Sarah Nelson, Jaimie K Beveridge, Richelle Mychasiuk, Melanie Noel,

The aims of this longitudinal study were to 1) identify categories of adverse childhood experiences (ACEs) (ie, neglect, abuse, household dysfunction in childhood) that increase risk for internalizing mental health problems, pain-related impairment, and poorer quality of life and 2) examine the moderating role of posttraumatic stress symptoms (PTSS) in ... Read more >>

J Pain (The journal of pain)
[2021, 22(10):1210-1220]

Cited: 1 time

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Immunotherapy for pancreatic ductal adenocarcinoma.

Eileen Carpenter, Sarah Nelson, Filip Bednar, Clifford Cho, Hari Nathan, Vaibhav Sahai, Marina Pasca di Magliano, Timothy L Frankel,

Pancreatic ductal adenocarcinoma (PDAC) remains a lethal cancer with an urgent need for better medical therapies. Efforts have been made to investigate the efficacy of immunotherapy, particularly given the hallmarks of immune suppression and exhaustion in PDAC tumors. Here, we review the molecular components responsible for the immune-privileged state in ... Read more >>

J Surg Oncol (Journal of surgical oncology)
[2021, 123(3):751-759]

Cited: 2 times

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Prognostic Value of a Structural Brain MRI Score in the Acute Phase of Aneurysmal Subarachnoid Hemorrhage: A Pilot Study.

Sarah E Nelson, Pirouz Piran, Jun Hua, Alexander Sigmon, Casey Weiner, Haris I Sair, Jose I Suarez, Robert D Stevens,

<h4>Background/objective</h4>Aneurysmal subarachnoid hemorrhage (aSAH) is associated with high morbidity and mortality despite advances in management. We evaluated the prognostic significance of a qualitative score using brain magnetic resonance imaging (MRI) features obtained early after aSAH.<h4>Methods</h4>Patients with aSAH were enrolled in a prospective observational cohort and underwent brain MRI during their ... Read more >>

Neurocrit Care (Neurocritical care)
[2021, :]

Cited: 0 times

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Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

Alexander G Bick, Joshua S Weinstock, Satish K Nandakumar, Charles P Fulco, Erik L Bao, Seyedeh M Zekavat, Mindy D Szeto, Xiaotian Liao, Matthew J Leventhal, Joseph Nasser, Kyle Chang, Cecelia Laurie, Bala Bharathi Burugula, Christopher J Gibson, Abhishek Niroula, Amy E Lin, Margaret A Taub, Francois Aguet, Kristin Ardlie, Braxton D Mitchell, Kathleen C Barnes, Arden Moscati, Myriam Fornage, Susan Redline, Bruce M Psaty, Edwin K Silverman, Scott T Weiss, Nicholette D Palmer, Ramachandran S Vasan, Esteban G Burchard, Sharon L R Kardia, Jiang He, Robert C Kaplan, Nicholas L Smith, Donna K Arnett, David A Schwartz, Adolfo Correa, Mariza de Andrade, Xiuqing Guo, Barbara A Konkle, Brian Custer, Juan M Peralta, Hongsheng Gui, Deborah A Meyers, Stephen T McGarvey, Ida Yii-Der Chen, M Benjamin Shoemaker, Patricia A Peyser, Jai G Broome, Stephanie M Gogarten, Fei Fei Wang, Quenna Wong, May E Montasser, Michelle Daya, Eimear E Kenny, Kari E North, Lenore J Launer, Brian E Cade, Joshua C Bis, Michael H Cho, Jessica Lasky-Su, Donald W Bowden, L Adrienne Cupples, Angel C Y Mak, Lewis C Becker, Jennifer A Smith, Tanika N Kelly, Stella Aslibekyan, Susan R Heckbert, Hemant K Tiwari, Ivana V Yang, John A Heit, Steven A Lubitz, Jill M Johnsen, Joanne E Curran, Sally E Wenzel, Daniel E Weeks, Dabeeru C Rao, Dawood Darbar, Jee-Young Moon, Russell P Tracy, Erin J Buth, Nicholas Rafaels, Ruth J F Loos, Peter Durda, Yongmei Liu, Lifang Hou, Jiwon Lee, Priyadarshini Kachroo, Barry I Freedman, Daniel Levy, Lawrence F Bielak, James E Hixson, James S Floyd, Eric A Whitsel, Patrick T Ellinor, Marguerite R Irvin, Tasha E Fingerlin, Laura M Raffield, Sebastian M Armasu, Marsha M Wheeler, Ester C Sabino, John Blangero, L Keoki Williams, Bruce D Levy, Wayne Huey-Herng Sheu, Dan M Roden, Eric Boerwinkle, JoAnn E Manson, Rasika A Mathias, Pinkal Desai, Kent D Taylor, Andrew D Johnson, , Paul L Auer, Charles Kooperberg, Cathy C Laurie, Thomas W Blackwell, Albert V Smith, Hongyu Zhao, Ethan Lange, Leslie Lange, Stephen S Rich, Jerome I Rotter, James G Wilson, Paul Scheet, Jacob O Kitzman, Eric S Lander, Jesse M Engreitz, Benjamin L Ebert, Alexander P Reiner, Siddhartha Jaiswal, Gonçalo Abecasis, Vijay G Sankaran, Sekar Kathiresan, Pradeep Natarajan,

Nature (Nature)
[2021, 591(7851):E27]

Cited: 1 time

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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.

Daniel Taliun, Daniel N Harris, Michael D Kessler, Jedidiah Carlson, Zachary A Szpiech, Raul Torres, Sarah A Gagliano Taliun, André Corvelo, Stephanie M Gogarten, Hyun Min Kang, Achilleas N Pitsillides, Jonathon LeFaive, Seung-Been Lee, Xiaowen Tian, Brian L Browning, Sayantan Das, Anne-Katrin Emde, Wayne E Clarke, Douglas P Loesch, Amol C Shetty, Thomas W Blackwell, Albert V Smith, Quenna Wong, Xiaoming Liu, Matthew P Conomos, Dean M Bobo, François Aguet, Christine Albert, Alvaro Alonso, Kristin G Ardlie, Dan E Arking, Stella Aslibekyan, Paul L Auer, John Barnard, R Graham Barr, Lucas Barwick, Lewis C Becker, Rebecca L Beer, Emelia J Benjamin, Lawrence F Bielak, John Blangero, Michael Boehnke, Donald W Bowden, Jennifer A Brody, Esteban G Burchard, Brian E Cade, James F Casella, Brandon Chalazan, Daniel I Chasman, Yii-Der Ida Chen, Michael H Cho, Seung Hoan Choi, Mina K Chung, Clary B Clish, Adolfo Correa, Joanne E Curran, Brian Custer, Dawood Darbar, Michelle Daya, Mariza de Andrade, Dawn L DeMeo, Susan K Dutcher, Patrick T Ellinor, Leslie S Emery, Celeste Eng, Diane Fatkin, Tasha Fingerlin, Lukas Forer, Myriam Fornage, Nora Franceschini, Christian Fuchsberger, Stephanie M Fullerton, Soren Germer, Mark T Gladwin, Daniel J Gottlieb, Xiuqing Guo, Michael E Hall, Jiang He, Nancy L Heard-Costa, Susan R Heckbert, Marguerite R Irvin, Jill M Johnsen, Andrew D Johnson, Robert Kaplan, Sharon L R Kardia, Tanika Kelly, Shannon Kelly, Eimear E Kenny, Douglas P Kiel, Robert Klemmer, Barbara A Konkle, Charles Kooperberg, Anna Köttgen, Leslie A Lange, Jessica Lasky-Su, Daniel Levy, Xihong Lin, Keng-Han Lin, Chunyu Liu, Ruth J F Loos, Lori Garman, Robert Gerszten, Steven A Lubitz, Kathryn L Lunetta, Angel C Y Mak, Ani Manichaikul, Alisa K Manning, Rasika A Mathias, David D McManus, Stephen T McGarvey, James B Meigs, Deborah A Meyers, Julie L Mikulla, Mollie A Minear, Braxton D Mitchell, Sanghamitra Mohanty, May E Montasser, Courtney Montgomery, Alanna C Morrison, Joanne M Murabito, Andrea Natale, Pradeep Natarajan, Sarah C Nelson, Kari E North, Jeffrey R O'Connell, Nicholette D Palmer, Nathan Pankratz, Gina M Peloso, Patricia A Peyser, Jacob Pleiness, Wendy S Post, Bruce M Psaty, D C Rao, Susan Redline, Alexander P Reiner, Dan Roden, Jerome I Rotter, Ingo Ruczinski, Chloé Sarnowski, Sebastian Schoenherr, David A Schwartz, Jeong-Sun Seo, Sudha Seshadri, Vivien A Sheehan, Wayne H Sheu, M Benjamin Shoemaker, Nicholas L Smith, Jennifer A Smith, Nona Sotoodehnia, Adrienne M Stilp, Weihong Tang, Kent D Taylor, Marilyn Telen, Timothy A Thornton, Russell P Tracy, David J Van Den Berg, Ramachandran S Vasan, Karine A Viaud-Martinez, Scott Vrieze, Daniel E Weeks, Bruce S Weir, Scott T Weiss, Lu-Chen Weng, Cristen J Willer, Yingze Zhang, Xutong Zhao, Donna K Arnett, Allison E Ashley-Koch, Kathleen C Barnes, Eric Boerwinkle, Stacey Gabriel, Richard Gibbs, Kenneth M Rice, Stephen S Rich, Edwin K Silverman, Pankaj Qasba, Weiniu Gan, , George J Papanicolaou, Deborah A Nickerson, Sharon R Browning, Michael C Zody, Sebastian Zöllner, James G Wilson, L Adrienne Cupples, Cathy C Laurie, Cashell E Jaquish, Ryan D Hernandez, Timothy D O'Connor, Gonçalo R Abecasis,

The Trans-Omics for Precision Medicine (TOPMed) programme seeks to elucidate the genetic architecture and biology of heart, lung, blood and sleep disorders, with the ultimate goal of improving diagnosis, treatment and prevention of these diseases. The initial phases of the programme focused on whole-genome sequencing of individuals with rich phenotypic ... Read more >>

Nature (Nature)
[2021, 590(7845):290-299]

Cited: 80 times

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The Clinical Utility of a Brief Psychological Stress Measure (Patient-Reported Outcomes Measurement Information System) in Youth with Chronic Pain.

Sarah Nelson, Maureen Burns, Deirdre Logan,

<h4>Objective</h4>To preliminarily examine the psychometric properties (i.e., internal consistency reliability, construct validity) and clinical utility of the Patient-Reported Outcomes Measurement Information System (PROMIS) psychological stress experiences scale in a sample of youth with chronic pain.<h4>Methods</h4>Participant data were gathered from an institutional review board (IRB) approved clinical data registry. One hundred ... Read more >>

Pain Med (Pain medicine (Malden, Mass.))
[2021, 22(1):91-99]

Cited: 3 times

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Green Flags and headache: A concept study using the Delphi method.

Heiko Pohl, Thien Phu Do, David García-Azorín, Jakob Møller Hansen, Espen Saxhaug Kristoffersen, Sarah E Nelson, Mark Obermann, Peter S Sandor, Christoph J Schankin, Henrik Winther Schytz, Alexandra Sinclair, Guus G Schoonman, Andreas R Gantenbein,

<h4>Objective</h4>The aim of this study was to collect and rate Green Flags, that is, symptoms or pieces of information indicating that a patient is more likely to suffer from a primary than from a secondary headache.<h4>Background</h4>When assessing headaches, a central question to be answered is whether the pain is primary ... Read more >>

Headache (Headache)
[2021, 61(2):300-309]

Cited: 0 times

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