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Western diet in ApoE-LDLR double-deficient mouse model of atherosclerosis leads to hepatic steatosis, fibrosis, and tumorigenesis.

Marian Kampschulte, Christiane Stöckl, Alexander C Langheinrich, Ulrike Althöhn, Rainer M Bohle, Gabriele A Krombach, Philipp Stieger, Yuri Churin, Sandra Kremer, Christian Dierkes, Timo Rath, Elke Roeb, Martin Roderfeld,

Nonalcoholic fatty liver disease has been linked to cardiovascular diseases and atherosclerosis. The aim of the current study was to characterize the hepatic pathology leading to fibrosis and tumors in a murine model of atherosclerosis. Male apolipoprotein E/low-density lipoprotein receptor double-knockout mice (AL) mice were fed with a high fat ... Read more >>

Lab Invest (Laboratory investigation; a journal of technical methods and pathology)
[2014, 94(11):1273-1282]

Cited: 16 times

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