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Author Sandra Helena Penha de Oliveira

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Effect of processing methods on the cytotoxicity of methyl methacrylate-based ocular prostheses: An in vitro study.

Emily Vivianne Freitas da Silva, Marcelo Coelho Goiato, Sandro Basso Bitencourt, Yoav Finer, Victor Gustavo Balera Brito, Aline Satie Takamiya, Sandra Helena Penha de Oliveira, Daniela Micheline Dos Santos,

The study evaluated the influence of cycles and methods of an ocular prosthesis resin on cytotoxicity toward human conjunctival cells. Resins were polymerized by water bath (WB, 74 °C or 100 °C for 30 min to 9 h), microwave (MW, 1200 W, 3 to 14 min and 30 s at 0 to 720 W), or autopolymerization (AP, room ... Read more >>

Toxicol In Vitro (Toxicology in vitro : an international journal published in association with BIBRA)
[2021, 76:105211]

Cited: 0 times

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Absence of human papillomavirus in cancer of the oral cavity and oropharynx in a Brazilian population.

Ingrid da Silva Santos, Lígia Lavezo Ferreira, Saygo Tomo, Sandra Helena Penha de Oliveira, Eder Ricardo Biasoli, Daniel Galera Bernabé, Luísa Lina Villa, Glauco Issamu Miyahara,

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2021, 30(4):350]

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What is the response profile of deciduous pulp fibroblasts stimulated with E. coli LPS and E. faecalis LTA?

Bella Luna Colombini-Ishikiriama, Thiago Jose Dionisio, Thais Francini Garbieri, Rafaela Alves da Silva, Maria Aparecida Andrade Moreira Machado, Sandra Helena Penha de Oliveira, Vanessa Soares Lara, Andrew Seth Greene, Carlos Ferreira Santos,

<h4>Background</h4>Oral fibroblast immunological responses to bacterial stimuli are well known. However, there are few studies about pulp fibroblasts from deciduous teeth (HDPF) responses, which are important for the treatment of pulp infections in children. The aim of this study was to evaluate expression and production of inflammatory cytokines and chemokines ... Read more >>

BMC Immunol (BMC immunology)
[2020, 21(1):38]

Cited: 0 times

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High p16INK4a immunoexpression is not HPV dependent in oral leukoplakia.

Saygo Tomo, Stephanye Pinto Biss, Marcelo Macedo Crivelini, Sandra Helena Penha de Oliveira, Éder Ricardo Biasoli, Kellen Cristine Tjioe, Daniel Galera Bernabé, Luisa Lina Villa, Glauco Issamu Miyahara,

<h4>Objective</h4>To evaluate the prevalence of HPV DNA detection in fresh tissue from oral leukoplakia by Linear Array assay, and its correlation with p16<sup>INK4a</sup> immunoexpression in the northwest region of the São Paulo state, Brazil.<h4>Patients and methods</h4>Fifty patients diagnosed with oral leukoplakia were included in the study. Sociodemographic, clinicopathologic and lifestyle ... Read more >>

Arch Oral Biol (Archives of oral biology)
[2020, 115:104738]

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Cytotoxicity and inflammatory response of different types of provisional restorative materials.

Marcio Campaner, Aline Satie Takamiya, Sandro Basso Bitencourt, Leticia Cerri Mazza, Sandra Helena Penha de Oliveira, Ricardo Shibayama, Valentim Adelino Ricardo Barão, Cortino Sukotjo, Aldiéris Alves Pesqueira,

AIM:To evaluate the cytotoxicity and inflammatory response of different types of provisional restorative materials to mice gingival fibroblasts. METHODS:Cytotoxicity of provisional material discs (thermal-polymerized acrylic resin; auto-polymerized acrylic resin; bisacrylic resin; nano-ceramic resin for CAD/CAM and prefabricated polymer block for CAD/CAM) to Mice (Balb/c) gingival cell were investigated under direct ... Read more >>

Arch Oral Biol (Archives of oral biology)
[2020, 111:104643]

Cited: 2 times

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Cytotoxicity and antimicrobial effects of citronella oil (Cymbopogon nardus) and commercial mouthwashes on S. aureus and C. albicans biofilms in prosthetic materials.

Bruno Guandalini Cunha, Cristiane Duque, Karina Sampaio Caiaffa, Loiane Massunari, Isabela Araguê Catanoze, Daniela Micheline Dos Santos, Sandra Helena Penha de Oliveira, Aimée Maria Guiotti,

Although the effectiveness of some mouthwashes has been proven, phytotherapy is still a field to be explored as an alternative to commercial products.<h4>Objective</h4>To evaluate, in vitro, the cytotoxicity and efficacy of two solutions based on citronella oil (CN), on S. aureus and C. albicans biofilms (in formation-adhesion phase and 24 h-biofilm ... Read more >>

Arch Oral Biol (Archives of oral biology)
[2020, 109:104577]

Cited: 2 times

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Cytotoxicity, Biocompatibility and Biomineralization of a New Ready-for-Use Bioceramic Repair Material.

Francine Benetti, Índia Olinta de Azevedo Queiroz, Leopoldo Cosme-Silva, Leticia Citelli Conti, Sandra Helena Penha de Oliveira, Luciano Tavares Angelo Cintra,

New mineral trioxide aggregate (MTA) formulations are constantly introduced in the market, usually in a powder-and-liquid form. Bioceramic (Bio-C) Repair is a ready-for-use material suggested as substitute for MTA, but its properties need to be studied. This study evaluated the cytotoxicity, biocompatibility and biomineralization of Bio-C Repair compared to MTA ... Read more >>

Braz Dent J (Brazilian dental journal)
[2019, 30(4):325-332]

Cited: 9 times

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Cytotoxicity and biocompatibility of a new bioceramic endodontic sealer containing calcium hydroxide.

Francine Benetti, Índia Olinta de Azevedo Queiroz, Pedro Henrique Chaves de Oliveira, Leticia Citelli Conti, Mariane Maffei Azuma, Sandra Helena Penha de Oliveira, Luciano Tavares Angelo Cintra,

This study evaluated the cytotoxicity and biocompatibility of a new bioceramic endodontic sealer (i.e., Sealer Plus BC) in comparison with those of MTA Fillapex and AH Plus. L929 fibroblasts were cultured and Alamar Blue was used to evaluate cell viability of diluted extracts (1:50, 1:100, and 1:200) from each sealer ... Read more >>

Braz Oral Res (Brazilian oral research)
[2019, 33:e042]

Cited: 2 times

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Effect of maternal periodontitis on GLUT4 and inflammatory pathway in adult offspring.

Maria Sara de Lima Coutinho Mattera, Fernando Yamamoto Chiba, Flávia Lombardi Lopes, Thaís Verônica Saori Tsosura, Maria Angelica Peres, Victor Gustavo Balera Brito, Sandra Helena Penha de Oliveira, Renato Felipe Pereira, Fernando Marani, Rodrigo Martins Dos Santos, Bianca Elvira Belardi, Gestter Willian Lattari Tessarin, Mariana Lopes Benites, Edilson Ervolino, Joel Claudio Heimann, Doris Hissako Sumida,

<h4>Background</h4>Maternal periodontal disease leads to low birth weight (LBW), insulin resistance (IR), increased TNF-α levels, and alterations in insulin signaling in adult offspring. TNF-α has been associated with the stimulation of IKKβ/NF-κB, resulting in the decreased expression of GLUT4. Another mechanism that may be involved in decreasing GLUT4 expression is ... Read more >>

J Periodontol (Journal of periodontology)
[2019, 90(8):884-893]

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Influence of Preparation and Exposure Periods of Eluates from Ocular Prosthesis Acrylic Resin in Human Conjunctival Cell Line

Emily Vivianne Freitas da Silva, Daniela Micheline dos Santos, Liliane da Rocha Bonatto, Victor Gustavo Balera Brito, Sandra Helena Penha de Oliveira, Marcelo Coelho Goiato,

<h4>Background</h4>This study was undertaken to analyze if different preparation and exposure periods of eluates from ocular prosthesis acrylic resin influence the cytotoxicity for conjunctival cells.<h4>Methods</h4>Twenty-four acrylic resin specimens were divided, according to the period of eluate exposure to Chang conjunctival cells (24 and 72 hours). Eluates were prepared in four ... Read more >>

Iran Biomed J (Iranian biomedical journal)
[2019, 23(1):78-86]

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Stress hormones concentrations in the normal microenvironment predict risk for chemically induced cancer in rats.

Vitor Bonetti Valente, Flávia Alves Verza, Felipe Yudi Kabeya Lopes, Joana Zafalon Ferreira, Paulo Sérgio Patto Dos Santos, Maria Lúcia Marçal Mazza Sundefeld, Éder Ricardo Biasoli, Glauco Issamu Miyahara, Ana Maria Pires Soubhia, Mariza de Andrade, Sandra Helena Penha de Oliveira, Daniel Galera Bernabé,

Evidence show that stress hormones can influence cancer progression, but its role in carcinogenesis is poorly understood. In this study, we used a new method based on oral carcinogenesis model in rats to test the hypothesis that physiological levels of stress hormones in the normal tissue microenvironment would have significant ... Read more >>

Psychoneuroendocrinology (Psychoneuroendocrinology)
[2018, 89:229-238]

Cited: 8 times

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Evaluation of the Cytotoxicity and Biocompatibility of New Resin Epoxy-based Endodontic Sealer Containing Calcium Hydroxide.

Luciano Tavares Angelo Cintra, Francine Benetti, Índia Olinta de Azevedo Queiroz, Luciana Louzada Ferreira, Loiane Massunari, Carlos Roberto Emerenciano Bueno, Sandra Helena Penha de Oliveira, João Eduardo Gomes-Filho,

INTRODUCTION:Many endodontic sealers are available, but the search for the ideal sealer continues. This study evaluated the cytotoxicity and biocompatibility of Sealer Plus, a new resin epoxy-based endodontic sealer containing calcium hydroxide. AH Plus, Endofill, and SimpliSeal endodontics sealers were used for comparison. METHODS:L929 fibroblasts were cultured, and an MTT ... Read more >>

J Endod (Journal of endodontics)
[2017, 43(12):2088-2092]

Cited: 14 times

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Endodontic infections increase leukocyte and lymphocyte levels in the blood.

Renata Oliveira Samuel, João Eduardo Gomes-Filho, Mariane Maffei Azuma, Dóris Hissako Sumida, Sandra Helena Penha de Oliveira, Fernando Yamamoto Chiba, Suely Regina Mogami Bomfim, Paulo César Ciarlini, Luis Gustavo Narciso, Luciano Tavares Angelo Cintra,

<h4>Objectives</h4>The aim of this study was to determine whether the presence of single or multiple apical periodontitis (AP) alters blood cell counts and cytokine production.<h4>Material and methods</h4>Thirty rats were divided into three groups: a control group comprising rats without AP, a group called 1AP comprising rats with AP in one ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2018, 22(3):1395-1401]

Cited: 3 times

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Periapical Lesions Increase Macrophage Infiltration and Inflammatory Signaling in Muscle Tissue of Rats.

Renato Felipe Pereira, Luciano Tavares Angelo Cintra, Gestter Willian Lattari Tessarin, Fernando Yamamoto Chiba, Maria Sara de Lima Coutinho Mattera, Natalia Francisco Scaramele, Thais Verônica Saori Tsosura, Edilson Ervolino, Sandra Helena Penha de Oliveira, Doris Hissako Sumida,

<h4>Introduction</h4>Our previous studies have shown that periapical lesions (PLs) in rats cause systemic disorders such as increased tumor necrosis factor-α plasma levels, insulin resistance, and impairment in insulin signal transduction in muscle tissue. However, the mechanisms involved in these alterations are not fully understood. Under chronic inflammatory conditions such as ... Read more >>

J Endod (Journal of endodontics)
[2017, 43(6):982-988]

Cited: 3 times

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Cytotoxicity, Biocompatibility, and Biomineralization of the New High-plasticity MTA Material.

Luciano Tavares Angelo Cintra, Francine Benetti, Índia Olinta de Azevedo Queiroz, Juliana Maria de Araújo Lopes, Sandra Helena Penha de Oliveira, Gustavo Sivieri Araújo, João Eduardo Gomes-Filho,

<h4>Introduction</h4>Mineral trioxide aggregate (MTA) has excellent biological properties, but its handling properties have been criticized for both ProRoot MTA (Tulsa Dental Products, Tulsa, OK) and white MTA-Angelus (MTA-Ang; Angelus Indústria de Produtos Odontológicos S/A, Londrina, PR, Brazil). Angelus MTA HP (high plasticity) (Angelus Indústria de Produtos Odontológicos S/A) has been ... Read more >>

J Endod (Journal of endodontics)
[2017, 43(5):774-778]

Cited: 23 times

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Toxicity analysis of ocular prosthesis acrylic resin with or without pigment incorporation in human conjunctival cell line.

Emily Vivianne Freitas da Silva, Marcelo Coelho Goiato, Liliane da Rocha Bonatto, Rodrigo Antonio de Medeiros, Daniela Micheline Dos Santos, Elidiane Cipriano Rangel, Sandra Helena Penha de Oliveira,

The aim of this study was to evaluate the influence of pigment incorporation on the cytotoxicity of ocular prosthesis N1 color acrylic resin. Nine samples were manufactured by heat-polymerization in water bath and divided into 3 groups: acrylic resin without pigment incorporation (group R), acrylic resin with pigment incorporation (group ... Read more >>

Toxicol In Vitro (Toxicology in vitro : an international journal published in association with BIBRA)
[2016, 36:180-185]

Cited: 1 time

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Effect of different methods of polymerizing ocular prosthesis acrylic resin on a human conjunctival cell line.

Emily Vivianne Freitas da Silva, Marcelo Coelho Goiato, Daniela Micheline Dos Santos, Liliane da Rocha Bonatto, Victor Gustavo Balera Brito, Sandra Helena Penha de Oliveira,

<h4>Statement of problem</h4>Ocular prosthesis acrylic resins should be biocompatible regardless of the polymerization method. The authors are unaware of a study that evaluated the biocompatibility of ocular prostheses.<h4>Purpose</h4>The purpose of this in vitro study was to evaluate the cytotoxicity of different methods of polymerizing ocular prosthesis acrylic resin. This was accomplished ... Read more >>

J Prosthet Dent (The Journal of prosthetic dentistry)
[2016, 116(5):818-823]

Cited: 4 times

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CCL3 and CXCL12 production in vitro by dental pulp fibroblasts from permanent and deciduous teeth stimulated by Porphyromonas gingivalis LPS.

Carla Renata Sipert, Ana Carolina de Faria Morandini, Karin Cristina da Silva Modena, Thiago José Dionísio, Maria Aparecida Andrade Moreira Machado, Sandra Helena Penha de Oliveira, Ana Paula Campanelli, Carlos Ferreira Santos,

<h4>Objective</h4>The aim of this study was to compare the production of the chemokines CCL3 and CXCL12 by cultured dental pulp fibroblasts from permanent (PDPF) and deciduous (DDPF) teeth under stimulation by Porphyromonas gingivalis LPS (PgLPS).<h4>Material and methods</h4>Primary culture of fibroblasts from permanent (n=3) and deciduous (n=2) teeth were established using ... Read more >>

J Appl Oral Sci (Journal of applied oral science : revista FOB)
[2013, 21(2):99-105]

Cited: 8 times

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Evaluation of photodynamic therapy on fibroblast viability and cytokine production.

João Eduardo Gomes-Filho, Gustavo Sivieri-Araujo, Carla Renata Sipert, Ludmilla Mota da Silva Santos, Índia Olinta de Azevedo Queiroz, Christine Men Martins, Nayara Kívilla do Carmo Maia, Luciano Tavares Angelo Cintra, Eloi Dezan-Junior, Vanderlei Salvador Bagnato, Antônio Hernandes Chaves-Neto, Sandra Helena Penha de Oliveira,

<h4>Background</h4>The aim of this study was to evaluate the effects of photodynamic therapy with curcumin (PDT) comparatively to 5% sodium hypochlorite (NaOCl) and saline solution on cell viability and cytokine (IL-1β and IL-6) production by mouse fibroblasts.<h4>Methods</h4>Sixty seconds of pre-irradiation time with curcumin 500mg/L and Led wavelength (λ) 480nm, 72Jcm(2), ... Read more >>

Photodiagnosis Photodyn Ther (Photodiagnosis and photodynamic therapy)
[2016, 13:97-100]

Cited: 3 times

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In vitro regulation of CCL3 and CXCL12 by bacterial by-products is dependent on site of origin of human oral fibroblasts.

Carla Renata Sipert, Ana Carolina Morandini, Thiago José Dionísio, Maria Aparecida Andrade Moreira Machado, Sandra Helena Penha Oliveira, Ana Paula Campanelli, Winston Patrick Kuo, Carlos Ferreira Santos,

<h4>Introduction</h4>Production of chemokines by tissue resident cells is one of the main mechanisms involved in the inflammatory infiltrate formation during inflammation. The specific ability of fibroblasts from different oral tissues such as gingiva, periodontal ligament, and dental pulp from permanent and deciduous teeth in producing the chemokines CCL3 and CXCL12 ... Read more >>

J Endod (Journal of endodontics)
[2014, 40(1):95-100]

Cited: 11 times

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Histologic characterization of engineered tissues in the canal space of closed-apex teeth with apical periodontitis.

João Eduardo Gomes-Filho, Paulo Carvalho Tobias Duarte, Edilson Ervolino, Suely Regina Mogami Bomfim, Caio José Xavier Abimussi, Ludmilla Mota da Silva Santos, Carolina Simonetti Lodi, Sandra Helena Penha De Oliveira, Elói Dezan, Luciano Tavares Angelo Cintra,

<h4>Introduction</h4>The aim of this study was to investigate the capacity of endodontic regenerative procedures combining an induced blood clot, platelet-rich plasma (PRP), and bone marrow aspirate (BMA) to regenerate dental pulp in canine closed-apex necrotic teeth.<h4>Methods</h4>Apical periodontitis was induced in 20 upper and lower premolars of 2 dogs. After biomechanical ... Read more >>

J Endod (Journal of endodontics)
[2013, 39(12):1549-1556]

Cited: 23 times

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Salivary alpha amylase and cortisol levels in children with global developmental delay and their relation with the expectation of dental care and behavior during the intervention.

Márcio José Possari dos Santos, Daniel Galera Bernabé, Ana Cláudia de Melo Stevanato Nakamune, Silvia Helena Venturoli Perri, Sandra Maria Herondina Coelho Ávila de Aguiar, Sandra Helena Penha de Oliveira,

The purpose of this study was to analyze the alpha-amylase (sAA) and cortisol levels in children with Global developmental delay (GDD) before and after dental treatment and its association with the children's behavior during treatment. The morning salivary cortisol levels and activity of sAA of 33 children with GDD were ... Read more >>

Res Dev Disabil (Research in developmental disabilities)
[2012, 33(2):499-505]

Cited: 5 times

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Periodontal tissue engineering after tooth replantation.

Luciana Reichert da Silva Assunção, Renato Colenci, Caril Constante Ferreira do-Amaral, Celso Koogi Sonoda, Suely Regina Mogami Bomfim, Roberta Okamoto, Marjorie de Assis Golim, Elenice Deffune, Célio Percinoto, Sandra Helena Penha de Oliveira,

<h4>Background</h4>Blood-derived products, platelet-poor plasma (PPP) and platelet-rich plasma (PRP), constitute an approach in the enhancement of tissue healing. PRP has also been used as a scaffold for bone marrow stem cells in tissue engineering. This study evaluates the effect of PPP, calcium chloride-activated PRP (PRP/Ca), calcium chloride- and thrombin-activated PRP ... Read more >>

J Periodontol (Journal of periodontology)
[2011, 82(5):758-766]

Cited: 10 times

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MTA-induced neutrophil recruitment: a mechanism dependent on IL-1beta, MIP-2, and LTB4.

Alessandra Cristina Gomes, João Eduardo Gomes Filho, Sandra Helena Penha de Oliveira,

<h4>Objective</h4>The objective of this study was to investigate the mediators and the resident peritoneal cells involved in the neutrophil migration (NM) induced by mineral trioxide aggregate (MTA) in mice.<h4>Study design</h4>MTA (25 mg/cavity) was injected into normal and pretreated peritoneal cavities (PC) with indomethacin (IND), dexamethasone (DEX), BWA4C, U75302, antimacrophage inflammatory ... Read more >>

Oral Surg Oral Med Oral Pathol Oral Radiol Endod (Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics)
[2008, 106(3):450-456]

Cited: 9 times

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Leukotriene B4 is essential for selective eosinophil recruitment following allergen challenge of CD4+ cells in a model of chronic eosinophilic inflammation.

Alessandra Bonacini Cheraim, Pedro Xavier-Elsas, Sandra Helena Penha de Oliveira, Tiago Batistella, Momtchilo Russo, Maria Ignez Gaspar-Elsas, Fernando Queiroz Cunha,

Subcutaneous heat-coagulated egg white implants (EWI) induce chronic, intense local eosinophilia in mice, followed by asthma-like responses to airway ovalbumin challenge. Our goal was to define the mechanisms of selective eosinophil accumulation in the EWI model. EWI carriers were challenged i.p. with ovalbumin and the contributions of cellular immunity and ... Read more >>

Life Sci (Life sciences)
[2008, 83(5-6):214-222]

Cited: 10 times

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