Full Text Journal Articles by
Author Samuel M Galvagno

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Comparison of a metronome-guided prehospital medication infusion technique with standard calculation: a simulated randomized, controlled, cross-over study.

Samuel M Galvagno, James Cloepin, Jeannie Hannas, Kurt S Rubach, Andrew Naumann, Jonathan Wendell,

<h4>Background</h4>Limited research regarding administration of timed medication infusions in the prehospital environment has identified wide variability with accuracy, timing, and overall feasibility. This study was a quality improvement project that utilized a randomized, controlled, crossover study design to compare two different educational techniques for medication infusion administration. We hypothesized that ... Read more >>

BMC Emerg Med (BMC emergency medicine)
[2021, 21(1):111]

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The Algorithm Examining the Risk of Massive Transfusion (ALERT) Score Accurately Predicts Massive Transfusion at the Scene of Injury and on Arrival to the Trauma Bay: A Retrospective Analysis.

Jonathan H Chow, Justin E Richards, Samuel M Galvagno, Patrick J Coleman, Allison S Lankford, Cheralyn Hendrix, Jackson Dunitz, Ikeoluwapo Ibrahim, Mira Ghneim, Kenichi A Tanaka, Thomas M Scalea, Michael A Mazzeffi, Peter Hu,

<h4>Background</h4>Massive transfusion (MT) is required to resuscitate traumatically injured patients with complex derangements. Scoring systems for MT typically require laboratory values and radiological imaging that may delay the prediction of MT.<h4>Study design</h4>The Trauma ALgorithm Examining the Risk of massive Transfusion (Trauma ALERT) study was an observational cohort study. Prehospital and ... Read more >>

Shock (Shock (Augusta, Ga.))
[2021, 56(4):529-536]

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Prehospital lactate is Associated with the Need for Blood in Trauma.

Eva V Zadorozny, Tyler Weigel, Andre Stone, Danielle S Gruen, Samuel M Galvagno, Mark H Yazer, Joshua B Brown, Francis X Guyette,

<i>Background:</i> Traumatic hemorrhage is the leading cause of preventable death, and its effects are often evident within the first 24 hours of hospital admission. We investigated the relationship between prehospital lactate measurement and administration of hospital blood products and life-saving interventions (LSIs) within 24 hours of hospital admission.<i>Methods</i>: We included trauma patients ... Read more >>

Prehosp Emerg Care (Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors)
[2021, :1-13]

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A descriptive evaluation of causes of death in venovenous extracorporeal membrane oxygenation.

Sagar B Dave, Kristopher B Deatrick, Samuel M Galvagno, Michael A Mazzeffi, David J Kaczorowski, Ronson J Madathil, Raymond Rector, Ali Tabatabai, Daniel J Haase, Daniel Herr, Thomas M Scalea, Jay Menaker,

Veno-venous extracorporeal membrane oxygenation (VV ECMO) has become an important support modality for patients with acute respiratory failure refractory to optimal medical therapy, such as low tidal volume mechanical ventilator support, early paralytic infusion, and early prone positioning. The objective of this cohort study was to investigate the causes and ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211035938]

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The Bitter and the Sweet: Relationship of Lactate, Glucose, and Mortality After Severe Blunt Trauma.

Justin E Richards, Michael A Mazzeffi, Michael S Massey, Peter Rock, Samuel M Galvagno, Thomas M Scalea,

<h4>Background</h4>Hyperglycemia is associated with mortality after trauma; however, few studies have simultaneously investigated the association of depth of shock and acute hyperglycemia. We evaluated lactate, as a surrogate measure for depth of shock, and glucose levels on mortality following severe blunt trauma. We hypothesize that measurements of both lactate and ... Read more >>

Anesth Analg (Anesthesia and analgesia)
[2021, 133(2):455-461]

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Regionalization of Critical Care in the United States: Current State and Proposed Framework From the Academic Leaders in Critical Care Medicine Task Force of the Society of the Critical Care Medicine.

Sharon Leung, Stephen M Pastores, John M Oropello, Craig M Lilly, Samuel M Galvagno, Neeraj Badjatia, Judith Jacobi, Daniel L Herr, Jason David Oliveira, ,

<h4>Objectives</h4>The Society of Critical Care Medicine convened its Academic Leaders in Critical Care Medicine taskforce on February 22, 2016, during the 45th Critical Care Congress to develop a series of consensus papers with toolkits for advancing critical care organizations in North America. The goal of this article is to propose ... Read more >>

Crit Care Med (Critical care medicine)
[2021, :]

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Extracorporeal Life Support (ECLS): A Review and Focus on Considerations for COVID-19.

Ali Tabatabai, Samuel M Galvagno, James V O'Connor, Thomas M Scalea, Kristopher B Deatrick,

<h4>Abstract</h4>Extracorporeal life support (ECLS) is a support modality for patients with severe acute respiratory distress syndrome (ARDS) who have failed conventional treatments including low tidal volume ventilation, prone positioning, and neuromuscular blockade. In addition, ECLS can be used for hemodynamic support for patients with cardiogenic shock or following cardiac arrest. ... Read more >>

Shock (Shock (Augusta, Ga.))
[2021, 55(6):742-751]

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Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With Coronavirus Disease 2019.

Jonathan H Chow, Ashish K Khanna, Shravan Kethireddy, David Yamane, Andrea Levine, Amanda M Jackson, Michael T McCurdy, Ali Tabatabai, Gagan Kumar, Paul Park, Ivy Benjenk, Jay Menaker, Nayab Ahmed, Evan Glidewell, Elizabeth Presutto, Shannon Cain, Naeha Haridasa, Wesley Field, Jacob G Fowler, Duy Trinh, Kathleen N Johnson, Aman Kaur, Amanda Lee, Kyle Sebastian, Allison Ulrich, Salvador Peña, Ross Carpenter, Shruti Sudhakar, Pushpinder Uppal, Benjamin T Fedeles, Aaron Sachs, Layth Dahbour, William Teeter, Kenichi Tanaka, Samuel M Galvagno, Daniel L Herr, Thomas M Scalea, Michael A Mazzeffi,

<h4>Background</h4>Coronavirus disease-2019 (COVID-19) is associated with hypercoagulability and increased thrombotic risk in critically ill patients. To our knowledge, no studies have evaluated whether aspirin use is associated with reduced risk of mechanical ventilation, intensive care unit (ICU) admission, and in-hospital mortality.<h4>Methods</h4>A retrospective, observational cohort study of adult patients admitted with ... Read more >>

Anesth Analg (Anesthesia and analgesia)
[2021, 132(4):930-941]

Cited: 66 times

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Expert consensus statements for the management of COVID-19-related acute respiratory failure using a Delphi method.

Prashant Nasa, Elie Azoulay, Ashish K Khanna, Ravi Jain, Sachin Gupta, Yash Javeri, Deven Juneja, Pradeep Rangappa, Krishnaswamy Sundararajan, Waleed Alhazzani, Massimo Antonelli, Yaseen M Arabi, Jan Bakker, Laurent J Brochard, Adam M Deane, Bin Du, Sharon Einav, Andrés Esteban, Ognjen Gajic, Samuel M Galvagno, Claude Guérin, Samir Jaber, Gopi C Khilnani, Younsuck Koh, Jean-Baptiste Lascarrou, Flavia R Machado, Manu L N G Malbrain, Jordi Mancebo, Michael T McCurdy, Brendan A McGrath, Sangeeta Mehta, Armand Mekontso-Dessap, Mervyn Mer, Michael Nurok, Pauline K Park, Paolo Pelosi, John V Peter, Jason Phua, David V Pilcher, Lise Piquilloud, Peter Schellongowski, Marcus J Schultz, Manu Shankar-Hari, Suveer Singh, Massimiliano Sorbello, Ravindranath Tiruvoipati, Andrew A Udy, Tobias Welte, Sheila N Myatra,

<h4>Background</h4>Coronavirus disease 2019 (COVID-19) pandemic has caused unprecedented pressure on healthcare system globally. Lack of high-quality evidence on the respiratory management of COVID-19-related acute respiratory failure (C-ARF) has resulted in wide variation in clinical practice.<h4>Methods</h4>Using a Delphi process, an international panel of 39 experts developed clinical practice statements on the ... Read more >>

Crit Care (Critical care (London, England))
[2021, 25(1):106]

Cited: 6 times

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Clinical Outcomes of Pregnant and Postpartum Extracorporeal Membrane Oxygenation Patients.

Allison S Lankford, Jonathan H Chow, Amanda M Jackson, Marianne Wallis, Samuel M Galvagno, Andrew M Malinow, Ozhan M Turan, Jay A Menaker, Sarah D Crimmins, Raymond Rector, David Kaczorowski, Bartley Griffith, Zachary Kon, Daniel Herr, Michael A Mazzeffi,

<h4>Background</h4>The use of extracorporeal membrane oxygenation (ECMO) as a rescue therapy for cardiopulmonary failure is expanding in critical care medicine. In this case series, we describe the clinical outcomes of 21 consecutive pregnant or postpartum patients that required venovenous (VV) or venoarterial (VA) ECMO. Our objective was to characterize maternal ... Read more >>

Anesth Analg (Anesthesia and analgesia)
[2021, 132(3):777-787]

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Breathing Life Back Into the Kidney-Continuous Renal Replacement Therapy and Veno-Venous Extracorporeal Membrane Oxygenation.

Kristopher B Deatrick, Michael A Mazzeffi, Samuel M Galvagno, Kimberly Boswell, David J Kaczoroswki, Ronald P Rabinowitz, Ronson J Madathil, Christopher R Cornachione, Daniel L Herr, Thomas M Scalea, Jay Menaker,

The purpose of this study was to evaluate the incidence of continuous renal replacement therapy (CRRT) in patients supported with veno-venous extracorporeal membrane oxygenation (VV ECMO). Secondary outcomes included mortality and the need for hemodialysis on hospital discharge. We performed a retrospective cohort study of all patients admitted to a ... Read more >>

ASAIO J (ASAIO journal (American Society for Artificial Internal Organs : 1992))
[2021, 67(2):208-212]

Cited: 4 times

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The Age Barrier for VV ECMO-Where Should It Be?

Samuel M Galvagno, Michael A Mazzeffi, K Barry Deatrick, Jay Menaker,

ASAIO J (ASAIO journal (American Society for Artificial Internal Organs : 1992))
[2021, 67(1):e56]

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A Retrospective Study of Infection in Patients Requiring Extracorporeal Membrane Oxygenation Support.

Megan T Quintana, Michael Mazzeffi, Samuel M Galvagno, Danny Herrera, Gregory P Boyajian, Nicole M Hays, David Kaczorowski, Ronson J Madathil, Raymond P Rector, Ali Tabatabai, Daniel Herr, Joseph Rabin,

<h4>Background</h4>Healthcare-associated infections (HAIs) in critically ill patients are a serious public health problem. Extracorporeal membrane oxygenation (ECMO) has been used increasingly for patients with severe cardiac or respiratory failure, but it may increase HAI risk. The goal of our study was to characterize HAIs in ECMO patients at an ECMO ... Read more >>

Ann Thorac Surg (The Annals of thoracic surgery)
[2021, 112(4):1168-1175]

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Tracheostomy in Patients on Venovenous Extracorporeal Membrane Oxygenation: Is It Safe?

Katherine M Kelley, Samuel M Galvagno, Marianne Wallis, Michael A Mazzeffi, Kristopher Deatrick, Richard Betzold, Thomas Scalea, Jay Menaker,

<h4>Background</h4>The anticoagulation and coagulopathy associated with venovenous extracorporeal membrane oxygenation (VV-ECMO) lead to concern for increased risks of tracheostomy. The purpose of this study is to evaluate the safety of tracheostomy in patients on VV-ECMO.<h4>Methods</h4>Patients admitted between November 2015 and January 2019 to a dedicated intensive care unit for VV-ECMO ... Read more >>

Am Surg (The American surgeon)
[2021, 87(8):1292-1298]

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Prehospital Point of Care Testing for the Early Detection of Shock and Prediction of Lifesaving Interventions.

Samuel M Galvagno, Robert A Sikorski, Douglas J Floccare, Peter Rock, Michael A Mazzeffi, Joseph J DuBose, Thomas M Scalea, Catriona Miller, Justin E Richards, James V O'Connor, Colin F Mackenzie, Peter Hu,

<h4>Introduction</h4>Early diagnosis and treatment are essential for enhancing outcomes for the traumatically injured. In this prospective prehospital observational study, we hypothesized that a variety of laboratory results measured in the prehospital environment would predict both the presence of early shock and the need for lifesaving interventions (LSIs) for adult patients ... Read more >>

Shock (Shock (Augusta, Ga.))
[2020, 54(6):710-716]

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Musculoskeletal Trauma in Critically Injured Patients: Factors Leading to Delayed Operative Fixation and Multiple Organ Failure.

Justin E Richards, Andrew J Medvecz, Nathan N O'Hara, Oscar D Guillamondegui, Robert V O'Toole, William T Obremskey, Samuel M Galvagno, Thomas M Scalea,

<h4>Background</h4>Musculoskeletal injuries are common following trauma and variables that are associated with late femur fracture fixation are important to perioperative management. Furthermore, the association of late fracture fixation and multiple organ failure (MOF) is not well defined.<h4>Methods</h4>We performed a retrospective cohort investigation from 2 academic trauma centers.<h4>Inclusion criteria</h4>age 18-89 years, ... Read more >>

Anesth Analg (Anesthesia and analgesia)
[2020, 131(6):1781-1788]

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Sedation for Rapid Sequence Induction and Intubation of Neurologically Injured Patients.

Jesse Shriki, Samuel M Galvagno,

There are subtle physiologic and pharmacologic principles that should be understood for patients with neurologic injuries. These principles are especially true for managing patients with traumatic brain injuries. Prevention of hypotension and hypoxemia are major goals in the management of these patients. This article discusses the physiology, pitfalls, and pharmacology ... Read more >>

Emerg Med Clin North Am (Emergency medicine clinics of North America)
[2021, 39(1):203-216]

Cited: 1 time

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Intoxication and overdose should not preclude veno-venous extracorporeal membrane oxygenation.

Jason S Radowsky, Michael M Mazzeffi, K Barry Deatrick, Samuel M Galvagno, Brandon M Parker, Ali Tabatabai, Ronson J Madathil, David J Kaczorowski, Ronald P Rabinowitz, Daniel L Herr, Thomas Scalea, Jay Menaker,

<h4>Introduction</h4>Acute intoxication (AI) related morbidity and mortality are increasing in the United States. For patients with severe respiratory failure in the setting of an acute ingestion, veno-venous extracorporeal membrane oxygenation (VV ECMO) can provide salvage therapy. The purpose of this study was to evaluate outcomes in patients with overdose-related need ... Read more >>

Perfusion (Perfusion)
[2020, :267659120963938]

Cited: 0 times

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The use of venous Doppler to predict adverse kidney events in a general ICU cohort.

Rory Spiegel, William Teeter, Scott Sullivan, Keegan Tupchong, Nabeel Mohammed, Mark Sutherland, Evan Leibner, Philippe Rola, Samuel M Galvagno, Sarah B Murthi,

<h4>Background</h4>Changes in Doppler flow patterns of hepatic veins (HV), portal vein (PV) and intra-renal veins (RV) reflect right atrial pressure and venous congestion; the feasibility of obtaining these assessments and the clinical relevance of the findings is unknown in a general ICU population. This study compares the morphology of HV, ... Read more >>

Crit Care (Critical care (London, England))
[2020, 24(1):615]

Cited: 2 times

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Does Weight Matter? Outcomes in Adult Patients on Venovenous Extracorporeal Membrane Oxygenation When Stratified by Obesity Class.

Samuel M Galvagno, Stacy Pelekhaty, Christopher R Cornachione, Kristopher B Deatrick, Michael A Mazzeffi, Thomas M Scalea, Jay Menaker,

<h4>Background</h4>Many believe obesity is associated with higher rates of mortality in the critically ill. The purpose of this retrospective observational study is to evaluate the association between body mass index (BMI) and survival in patients receiving venovenous (VV) extracorporeal membrane oxygenation (ECMO) for acute hypoxic or hypercarbic respiratory failure.<h4>Methods</h4>All of ... Read more >>

Anesth Analg (Anesthesia and analgesia)
[2020, 131(3):754-761]

Cited: 7 times

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Outcomes of Venovenous Extracorporeal Membrane Oxygenation When Stratified by Age: How Old Is Too Old?

Kristopher B Deatrick, Michael A Mazzeffi, Samuel M Galvagno, Ronald B Tesoriero, David J Kaczoroswki, Daniel L Herr, Katelyn Dolly, Ronald P Rabinowitz, Thomas M Scalea, Jay Menaker,

The purpose of this study was to evaluate survival to hospital discharge for patients on venovenous extracorporeal membrane oxygenation (VV ECMO) when stratified by age. We performed a retrospective study at single, academic, tertiary care center intensive care unit for VV ECMO. All patients, older than 17 years of age, ... Read more >>

ASAIO J (ASAIO journal (American Society for Artificial Internal Organs : 1992))
[2020, 66(8):946-951]

Cited: 4 times

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The effect of platelet transfusion on functional independence and mortality after antiplatelet therapy associated spontaneous intracerebral hemorrhage: A systematic review and meta-analysis.

Nicholas A Morris, Nikhil Patel, Samuel M Galvagno, Emilie Ludeman, Gary T Schwartzbauer, Ali Pourmand, Quincy K Tran,

<h4>Introduction</h4>The practice of platelet transfusion to mitigate the deleterious effects of antiplatelet agents on spontaneous intracerebral hemorrhage (ICH) remains common. However, the effect of antiplatelet agents on patients with ICH is still controversial and transfusing platelets is not without risk. We performed a meta-analysis in order to determine the effect ... Read more >>

J Neurol Sci (Journal of the neurological sciences)
[2020, 417:117075]

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COVID-Activated Emergency Scaling of Anesthesiology Responsibilities Intensive Care Unit.

Ricardo E Verdiner, Christopher G Choukalas, Shahla Siddiqui, David L Stahl, Samuel M Galvagno, Craig S Jabaley, Raquel R Bartz, Meghan Lane-Fall, Kristina L Goff, Roshni Sreedharan, Suzanne Bennett, George W Williams, Ashish K Khanna,

In response to the rapidly evolving coronavirus disease 2019 (COVID-19) pandemic and the potential need for physicians to provide critical care services, the American Society of Anesthesiologists (ASA) has collaborated with the Society of Critical Care Anesthesiologists (SOCCA), the Society of Critical Care Medicine (SCCM), and the Anesthesia Patient Safety ... Read more >>

Anesth Analg (Anesthesia and analgesia)
[2020, 131(2):365-377]

Cited: 1 time

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Extracorporeal Membrane Oxygenation for COVID-19.

Zachary Sanford, Ronson J Madathil, Kristopher B Deatrick, Ali Tabatabai, Jay Menaker, Samuel M Galvagno, Michael A Mazzeffi, Joseph Rabin, Mehrdad Ghoreishi, Raymond Rector, Daniel L Herr, David J Kaczorowski,

Innovations (Phila) (Innovations (Philadelphia, Pa.))
[2020, 15(4):306-313]

Cited: 0 times

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Shock, Not Blood Pressure or Shock Index, Determines the Need for Thoracic Damage Control Following Penetrating Trauma.

Molly Deane, Samuel M Galvagno, Benjamin Moran, Deborah M Stein, Thomas M Scalea, James V O'Connor,

<h4>Background</h4>Damage control laparotomy has increased survival for critically injured patient with penetrating abdominal trauma. There has been a slower adoption of a damage control strategy for thoracic trauma despite the considerable mortality associated with emergent thoracotomy for patients in profound shock. We postulated admission physiology, not blood pressure or shock ... Read more >>

Shock (Shock (Augusta, Ga.))
[2020, 54(1):4-8]

Cited: 1 time

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