Full Text Journal Articles by
Author Sachin Gupta

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COVID-19 Is Not Comparable to H1N1 Influenza.

Ravindranath Tiruvoipati, Sachin Gupta, Kavi Haji,

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2021, :]

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Experiences From an Implementation Model of ARI Diagnostic Device in Pneumonia Case Management Among Under-5 Children in Peripheral Healthcare Centers in India.

Harish Kumar, Enisha Sarin, Prasant Saboth, Avinash Jaiswal, Nidhi Chaudhary, Jaya Swarup Mohanty, Nitin Bisht, Shailendra Singh Tomar, Anil Gupta, Ranjan Panda, Rachana Patel, Arvind Kumar, Sachin Gupta, Varun Alwadhi,

<h4>Objectives</h4>To address pneumonia, a major killer of under-5 children in India, a multimodal pulse oximeter was implemented in Health and Wellness Centers. Given the evidence of pulse oximetry in effective pneumonia management and taking into account the inadequate skills of front-line healthcare workers in case management, the device was introduced ... Read more >>

Clin Med Insights Pediatr (Clinical medicine insights. Pediatrics)
[2021, 15:11795565211056649]

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Healthy Eating Index (HEI) Scores Differ by Race/Ethnicity But Not Hypertension Awareness Status Among US Adults with Hypertension: Findings from 2011-2018 National Health and Nutrition Examination Survey.

Yining Ma, Xingran Weng, Xiang Gao, Renate Winkels, Yendelela Cuffee, Sachin Gupta, Li Wang,

<h4>Background</h4>Little is known about whether diet quality is associated with race/ethnicity as well as hypertension awareness status among adults with hypertension.<h4>Objective</h4>The aim of this study was to examine associations between diet quality and race/ethnicity as well as hypertension awareness.<h4>Design</h4>Analysis of the 2011-2018 National Health and Nutrition Examination Survey (NHANES), a ... Read more >>

J Acad Nutr Diet (Journal of the Academy of Nutrition and Dietetics)
[2021, :]

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GLRX5-associated [Fe-S] cluster biogenesis disorder: further characterisation of the neurological phenotype and long-term outcome.

Bindu Parayil Sankaran, Sachin Gupta, Michel Tchan, Beena Devanapalli, Yusof Rahman, Peter Procopis, Kaustuv Bhattacharya,

<h4>Background</h4>Identification and characterisation of monogenic causes of complex neurological phenotypes are important for genetic counselling and prognostication. Bi-allelic pathogenic variants in the gene encoding GLRX5, a protein involved in the early steps of Fe-S cluster biogenesis, are rare and cause two distinct phenotypes: isolated sideroblastic anemia and a neurological phenotype ... Read more >>

Orphanet J Rare Dis (Orphanet journal of rare diseases)
[2021, 16(1):465]

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Use of predictive models to identify patients who are likely to benefit from refraction at a follow-up visit after cataract surgery.

Sachin Gupta, Matthew J Schneider, S Ashok Vardhan, Thulasiraj Ravilla,

<h4>Purpose</h4>To develop predictive models to identify cataract surgery patients who are more likely to benefit from refraction at a four-week postoperative exam.<h4>Methods</h4>In this retrospective study, we used data of all 86,776 cataract surgeries performed in 2015 at a large tertiary-care eye hospital in India. The outcome variable was a binary ... Read more >>

Indian J Ophthalmol (Indian journal of ophthalmology)
[2021, 69(10):2695-2701]

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Care Around Birth Approach: A Training, Mentoring, and Quality Improvement Model to Optimize Intrapartum and Immediate Postpartum Quality of Care in India.

Gunjan Taneja, Enisha Sarin, Devina Bajpayee, Saumyadripta Chaudhuri, Geeta Verma, Rakesh Parashar, Nidhi Chaudhry, Jaya Swarup Mohanty, Nitin Bisht, Anil Gupta, Shailendra Singh Tomar, Rachana Patel, V S Sridhar, Anurag Joshi, Chitra Rathi, Dinesh Baswal, Sachin Gupta, Rajeev Gera,

<h4>Background</h4>With the highest risk of maternal and newborn mortality occurring during the period around birth, quality of care during the intrapartum and immediate postpartum periods is critical for maternal and neonatal survival.<h4>Methods</h4>The United States Agency for International Development's Scaling Up Reproductive, Maternal, Newborn, Child, and Adolescent Health Interventions project, also ... Read more >>

Glob Health Sci Pract (Global health, science and practice)
[2021, 9(3):590-610]

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Fabrication and delivery of mechano-actived microcapsules containing osteogenic factors in a large animal model of osteochondral injury

Hannah Zlotnick, Ryan Locke, Sanjana Hemdev, Brendan Stoeckl, Sachin Gupta, Ana Peredo, David Steinberg, James Carey, Daeyeon Lee, George Dodge, Robert Mauck,

Chondral and osteochondral repair strategies are limited by adverse bony changes that occur after injury. Bone resorption can cause entire scaffolds, engineered tissues, or even endogenous repair tissues to subside below the cartilage surface. To address this translational issue, we fabricated poly(D,L-lactide-co-glycolide) (PLGA) microcapsules containing the pro-osteogenic agents triiodothyronine and ... Read more >>

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Safety of Alcohol-Based Hand Sanitizers in Behavioral Health Facilities.

Vinicius Jorge, Karla Curet, Ragia Aly, Sachin Gupta, Sorab Gupta, Horacio Hares,

Am J Med Qual (American journal of medical quality : the official journal of the American College of Medical Quality)
[2021, 36(5):372]

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Omalizumab in Asthma with Fixed Airway Obstruction: Post Hoc Analysis of EXTRA.

Nicola A Hanania, Spyridon Fortis, Tmirah Haselkorn, Sachin Gupta, Nayla Mumneh, Bongin Yoo, Cecile T J Holweg, Bradley E Chipps,

<h4>Background</h4>Although asthma is typically characterized by bronchodilator responsiveness (BDR), fixed airflow obstruction (FAO) occurs in ∼50% of patients with severe asthma.<h4>Objective</h4>Do FAO/BDR associate with efficacy of omalizumab, a monoclonal antibody that targets IgE?<h4>Methods</h4>In EXTRA, patients aged 12-75 years with inadequately controlled severe allergic asthma despite high-dose inhaled corticosteroids plus long-acting ... Read more >>

J Allergy Clin Immunol Pract (The journal of allergy and clinical immunology. In practice)
[2021, :]

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An Exploratory Analysis of the Association between Hypercapnia and Hospital Mortality in Critically Ill Patients with Sepsis.

Ravindranath Tiruvoipati, Ary Serpa Neto, Marcus Young, Nada Marhoon, John Wilson, Sachin Gupta, David Pilcher, Michael Bailey, Rinaldo Bellomo,

<h4>Rationale</h4>Hypercapnia may affect the outcome of sepsis. Very few clinical studies conducted in non-critically ill patients, have investigated the effects of hypercapnia and hypercapnic acidemia in the context of sepsis. The effect of hypercapnia in critically ill patients with sepsis remains inadequately studied.<h4>Objective</h4>To investigate the association of hypercapnia with hospital ... Read more >>

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2021, :]

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Usage of Direct Acting Oral Anticoagulants in Cirrhotic and Non-Cirrhotic Portal Vein Thrombosis: A Systematic Review.

Sachin Gupta, Jessica Hidalgo, Balraj Singh, Aditya Iyer, Yang Yang, Alexandra Short, Sandeep Singh, Harshil Bhatt, Sorab Gupta,

Thrombosis of the portal vein (PVT) is generally seen in the setting of liver cirrhosis and to a lesser extent in the absence of cirrhosis. There is no clear guidance in relation to approaching treatment with anticoagulation in this condition. The professional societies and guidelines recommend treatment with traditional anticoagulation ... Read more >>

Cureus (Cureus)
[2021, 13(8):e16922]

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Opioid use after endoscopic skull base surgery: A descriptive, prospective, longitudinal cohort study.

Ryan A Rimmer, Brian Scott, Jasmina Pailet, Nyssa Fox Farrell, Jess C Mace, Kara Y Detwiller, Timothy L Smith, Aclan Dogan, Sachin Gupta, Peter Andersen, Justin Cetas, Mathew Geltzeiler,

<h4>Background</h4>Opioid abuse is a public health crisis and the perioperative period can be a time of first opioid exposure. Little is known about postoperative pain management after endoscopic skull base surgery (ESBS).<h4>Methods</h4>This investigation was a single-institution, longitudinal, prospective cohort study of adult patients undergoing ESBS between November 2019 and March ... Read more >>

Int Forum Allergy Rhinol (International forum of allergy & rhinology)
[2021, :]

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Checkpoint Inhibitors in Relapsed/Refractory Classical Hodgkin Lymphoma.

Kidist Tarekegn, Ana Colon Ramos, Balraj Singh, Harry G Sequeira Gross, Sachin Gupta,

Even though classical Hodgkin lymphoma is highly curable, the outcome of patients with a refractory or relapsed disease has been disappointing. Multiple lines of therapy are available for patients after their first failure, and most respond to subsequent therapies. However, there is a sizable proportion that remains relapsing/recurrent even after ... Read more >>

World J Oncol (World journal of oncology)
[2021, 12(4):81-84]

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Paradigm shift in the management of metastatic nonsmall cell lung cancer.

Ruby Gupta, Melanie Smalley, Nwabundo Anusim, Vishal Jindal, Mandeep Singh Rahi, Sorab Gupta, Sachin Gupta, Ishmael Jaiyesimi,

<h4>Background</h4>Lung cancer is one of the leading causes of cancer mortality in the United States. The use of precision medicine in the past 10 years has significantly changed the therapeutic landscape of lung cancer. Management of advanced nonsmall cell lung cancer (NSCLC) has transitioned from a chemotherapeutic approach to targeted treatments and ... Read more >>

Int J Clin Pract (International journal of clinical practice)
[2021, 75(11):e14533]

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GLRX5-associated [Fe-S] Cluster Biogenesis Disorder: Further Characterisation of the Neurological Phenotype and Long-term Outcome.

Bindu Parayil Sankaran, Sachin Gupta, Michel Tchan, Beena Devanapalli, Yusof Rahman, Peter Procopis, Kaustuv Bhattacharya,

<h4>Background: </h4> Identification and characterisation of monogenic causes of complex neurological phenotypes are important for genetic counselling and prognostication. Bi-allelic pathogenic variants in the gene encoding GLRX5, a protein involved in the early steps of Fe-S cluster biogenesis, are rare and cause two distinct phenotypes: isolated sideroblastic anemia and a ... Read more >>

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Leukocytosis and Spurious Hypoxemia.

Sachin Gupta, Sushma Medikayala, Balraj Singh, Harshil Bhatt, Sandeep Singh,

Abnormally low pO2 and oxygen saturations on arterial blood gases (ABGs) test have been reported in the patients who have very high WBC and platelet counts; generally in the setting of hematological malignancies. This is presumably related to the consumption of oxygen by the active cellular elements in the arterial blood sample ... Read more >>

Cureus (Cureus)
[2021, 13(6):e15942]

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Case Report: Heparin-induced thrombocytopenia in a patient with COVID-19

Ragia Aly, Sachin Gupta, Sorab Gupta, Balraj Singh, Abhinav Goyal, Sheila Kalathil,

<ns3:p>With the spread of the novel coronavirus disease of 2019 (COVID-19) worldwide and associated high incidence of thromboembolic complications, the use of heparin is on the rise. It therefore is crucial to identify patients with contraindications for heparin. Heparin-induced thrombocytopenia (HIT) is a life-threatening complication of exposure to heparin. We report ... Read more >>

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A Case of Systemic Toxicity Related to Intravesical Bacillus Calmette-Guerin for the Treatment of Bladder Cancer.

Sachin Gupta, Balraj Singh, Harshil Bhatt, Sandeep Singh, Sorab Gupta,

Intravesical administration of Bacillus Calmette-Guerin (BCG) has been utilized for the treatment of superficial bladder cancer for the past several decades. Though this treatment is well tolerated in general, both local and systematic side effects have been reported. We present a case of a patient who presented with systemic symptoms ... Read more >>

Cureus (Cureus)
[2021, 13(5):e15321]

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The association between frailty and clinical outcomes in hospitalised patients requiring Code Blue activation.

Hamish Brown, Matthew Donnan, Jonathan McCafferty, Taya Collyer, Ravindranath Tiruvoipati, Sachin Gupta,

<h4>Background</h4>Code Blues allow a rapid, hospital wide response to acutely deteriorating patients. The concept of frailty is being increasingly recognised as an important element in determining outcomes of critically ill patients. We hypothesised that increasing frailty would be associated with worse outcomes following a Code Blue.<h4>Aims</h4>We investigated the association between ... Read more >>

Intern Med J (Internal medicine journal)
[2021, :]

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Do Not Miss the Tumor: A Novel Presentation of Osteosarcoma.

Michael DePalma, Sachin Gupta, Jie Nguyen, Divya Talwar, Alexandre Arkader, Lawrence Wells,

Antalgic gait is a common clinical presentation among pediatric patients and can have many different etiologies, with rare life-threatening etiologies including primary bone malignancies. Osteosarcoma is the most common primary malignancy of bone in pediatric and adolescent patients. The incidence rate of osteosarcoma has been reported as high as 5 ... Read more >>

Case Rep Pediatr (Case reports in pediatrics)
[2021, 2021:5531238]

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Response to comments: Making the decision to donate eye organs: Perspectives from the families of the deceased in Madurai, India.

Ganesh-Babu B Subburaman, John H Kempen, Saravanan Duraisamy, Balakrishnan Vijayakumar, Vijayakumar Valaguru, Venkatesh Prajna Namperumalsamy, Thulasiraj D Ravilla, Sachin Gupta,

Indian J Ophthalmol (Indian journal of ophthalmology)
[2021, 69(4):1020-1021]

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The use of direct acting oral anticoagulants in patients with COVID-19 infection.

Ragia Aly, Sachin Gupta, Balraj Singh, Parminder Kaur, Kunhwa Kim, Sorab Gupta,

The use of direct-acting oral anticoagulants (DOACs) has increased rapidly in the last decade; becoming the mainstay for both the prophylaxis and the treatment of venous thromboembolism in various situations including non-valvular atrial fibrillation, joint replacement surgeries and acute DVT/PE, etc. In the present times, DOACs are possibly one of ... Read more >>

J Community Hosp Intern Med Perspect (Journal of community hospital internal medicine perspectives)
[2021, 11(2):184-186]

Cited: 2 times

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Comparison of clinical outcomes between nurse practitioner and registrar-led medical emergency teams: a propensity-matched analysis.

Sachin Gupta, Mayurathan Balachandran, Gaby Bolton, Naomi Pratt, Jo Molloy, Eldho Paul, Ravindranath Tiruvoipati,

<h4>Objective</h4>Medical emergency teams (MET) are mostly led by physicians. Some hospitals are currently using nurse practitioners (NP) to lead MET calls. These are no studies comparing clinical outcomes between these two care models. To determine whether NP-led MET calls are associated with lower risk of acute patient deterioration, when compared ... Read more >>

Crit Care (Critical care (London, England))
[2021, 25(1):117]

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Pancreatic cancer presenting with pulmonary cannonball lesions.

Balraj Singh, Sydney Fasulo, Parminder Kaur, Beenish Faheen, Sarah Ayad, Sachin Gupta, Michael Maroules,

Cannonball lesions are numerous, well-circumscribed, round pulmonary lesions and may be identified on plain radiograph or advanced imaging. This morphology can be associated with infectious causes, rheumatologic disease and metastatic disease. Classically, when cannonball lesions are associated with metastatic disease, they are seen in renal cell carcinoma and choriocarcinoma. We ... Read more >>

Radiol Case Rep (Radiology case reports)
[2021, 16(5):1179-1182]

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COVID-19-Induced Hyperleucocytosis in Chronic Lymphocytic Leukaemia.

Balraj Singh, Sarah Ayad, Parminder Kaur, Ro-Jay Reid, Sachin Gupta, Michael Maroules,

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus responsible for the current global pandemic, coronavirus disease 2019 (COVID-19). COVID-19 usually presents with respiratory symptoms but can affect multiple organ systems. A wide spectrum of complications can occur depending upon the comorbidities of patients. There is limited literature ... Read more >>

Eur J Case Rep Intern Med (European journal of case reports in internal medicine)
[2021, 8(3):002348]

Cited: 1 time

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