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Author Sabyasachi Roy

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The Emerging Role of Artificial Intelligence in the Fight Against COVID-19.

Aruni Ghose, Sabyasachi Roy, Nikhil Vasdev, Jonathon Olsburgh, Prokar Dasgupta,

The coronavirus disease 2019 (COVID-19) pandemic has generated large volumes of clinical data that can be an invaluable resource towards answering a number of important questions for this and future pandemics. Artificial intelligence can have an important role in analysing such data to identify populations at higher risk of COVID-19-related ... Read more >>

Eur Urol (European urology)
[2020, 78(6):775-776]

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Carbon nanodot decorated acellular dermal matrix hydrogel augments chronic wound closure.

Kamakshi Bankoti, Arun Prabhu Rameshbabu, Sayanti Datta, Madhurima Roy, Piyali Goswami, Sabyasachi Roy, Amit Kumar Das, Sudip Kumar Ghosh, Santanu Dhara,

Impaired skin regeneration in chronic wounds like in diabetes corresponds to high oxidative stress, poor angiogenesis and insufficient collagen hyperplasia. Therefore, a multifaceted strategy for treatment is required to address critical issues associated with chronic wound healing. Fascinating application of nanomaterials in chronic wounds is still limited; hence, in the ... Read more >>

J Mater Chem B (Journal of materials chemistry. B)
[2020, 8(40):9277-9294]

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Polymeric micelles based on amphiphilic oleic acid modified carboxymethyl chitosan for oral drug delivery of bcs class iv compound: Intestinal permeability and pharmacokinetic evaluation.

Rahul Kumar, Arvind Sirvi, Shamandeep Kaur, Sanjaya K Samal, Sabyasachi Roy, Abhay T Sangamwar,

Chemical modification of chitosan derivatives with hydrophobic fatty acids to enhance their self-aggregation behavior is well established. Previously our group reported low molecular weight carboxymethyl chitosan (CMCS) which showed enhancement in apparent permeability of hydrophobic drug, tamoxifen. Further extension to this work, herein we synthesize a new polymer of oleic ... Read more >>

Eur J Pharm Sci (European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences)
[2020, 153:105466]

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Successful oral delivery of fexofenadine hydrochloride by improving permeability via phospholipid complexation.

Mandeep, Shamandeep Kaur, Sanjaya K Samal, Sabyasachi Roy, Abhay T Sangamwar,

The present work aimed to enhance liposolubility along with intestinal permeability of BCS class III drug fexofenadine (FEX) via phospholipid complexation strategy in order to improve its oral bioavailability. This work demonstrated the minimized P-gp efflux and augmented absorption of FEX when fabricated as phospholipid complex. The fexofenadine-phospholipid complex (FEX-PLC) ... Read more >>

Eur J Pharm Sci (European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences)
[2020, 149:105338]

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Bioinspired 3D porous human placental derived extracellular matrix/silk fibroin sponges for accelerated bone regeneration.

Arun Prabhu Rameshbabu, Kamakshi Bankoti, Sayanti Datta, Elavarasan Subramani, Anupam Apoorva, Paulomi Ghosh, Subhodeep Jana, Padmavati Manchikanti, Sabyasachi Roy, Koel Chaudhury, Santanu Dhara,

Critical bone defects arising from traumatic injury and diseases are of major health concern since they are unable to heal spontaneously without clinical intervention. In this context, bone tissue engineering provides an attractive approach to treat bone defects by providing a bioactive template which has the potential to guide osseous ... Read more >>

Mater Sci Eng C Mater Biol Appl (Materials science & engineering. C, Materials for biological applications)
[2020, 113:110990]

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Rapid modulations of the vocal structure in marmoset monkeys.

Lingyun Zhao, Sabyasachi Roy, Xiaoqin Wang,

Humans and some animal species show flexibility in vocal production either voluntarily or in response to environmental cues. Studies have shown rapid spectrotemporal changes in speech or vocalizations during altered auditory feedback in humans, songbirds and bats. Non-human primates, however, have long been considered lacking the ability to modify spectrotemporal ... Read more >>

Hear Res (Hearing research)
[2019, 384:107811]

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Oleoyl-Chitosan-Based Nanofiber Mats Impregnated with Amniotic Membrane Derived Stem Cells for Accelerated Full-Thickness Excisional Wound Healing.

Sayanti Datta, Arun Prabhu Rameshbabu, Kamakshi Bankoti, Priti Prasanna Maity, Dipankar Das, Sagar Pal, Sabyasachi Roy, Ramkrishna Sen, Santanu Dhara,

Wound healing management is a major challenge for critical full-thickness skin wounds. Development of nanofibrous scaffolds with tunable wettability, degradation, and biocompatibility are highly desirable. Herein, we demonstrated synthesis of oleoyl chitosan (OC) by grafting monounsaturated fatty acid residue, C<sub>18</sub> oleoyl chain, to the backbone of chitosan molecule and blending ... Read more >>

ACS Biomater Sci Eng (ACS biomaterials science & engineering)
[2017, 3(8):1738-1749]

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Distinct Neural Activities in Premotor Cortex during Natural Vocal Behaviors in a New World Primate, the Common Marmoset (Callithrix jacchus).

Sabyasachi Roy, Lingyun Zhao, Xiaoqin Wang,

Although evidence from human studies has long indicated the crucial role of the frontal cortex in speech production, it has remained uncertain whether the frontal cortex in nonhuman primates plays a similar role in vocal communication. Previous studies of prefrontal and premotor cortices of macaque monkeys have found neural signals ... Read more >>

J Neurosci (The Journal of neuroscience : the official journal of the Society for Neuroscience)
[2016, 36(48):12168-12179]

Cited: 8 times

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Defining the possibilities: is short duration treatment of chronic hepatitis C genotype 1 with sofosbuvir-containing regimens likely to be as effective as current regimens?

Shirin Nafisi, Sabyasachi Roy, Robert Gish, Richard Manch, Anita Kohli,

<h4>Unlabelled</h4>This review summarizes published data on sofosbuvir-based regimens for patients infected with HCV GT1 with a focus on evaluating the optimal and possible durations of treatment.<h4>Methods</h4>PubMed and conference abstract books published between 2011-2015 were searched.<h4>Results</h4>HCV treatment has decreased from 24 week regimens to studies done as short as 4 weeks. ... Read more >>

Expert Rev Anti Infect Ther (Expert review of anti-infective therapy)
[2016, 14(1):41-56]

Cited: 2 times

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Investigating the potential of human placenta-derived extracellular matrix sponges coupled with amniotic membrane-derived stem cells for osteochondral tissue engineering.

Arun Prabhu Rameshbabu, Paulomi Ghosh, Elavarasan Subramani, Kamakshi Bankoti, Kausik Kapat, Sayanti Datta, Priti Prasana Maity, Bhuvaneshwaran Subramanian, Sabyasachi Roy, Koel Chaudhury, Santanu Dhara,

Osteochondral injuries are challenging to repair due to their complex tissue anatomy and restricted self-repairing ability associated with a limited blood supply. Osteochondral tissue engineering is an important clinical aspect of the management and treatment of cartilage and underlying bone. In the present study, we fabricated human placenta-derived extracellular matrix ... Read more >>

J Mater Chem B (Journal of materials chemistry. B)
[2016, 4(4):613-625]

Cited: 2 times

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Wireless multi-channel single unit recording in freely moving and vocalizing primates.

Sabyasachi Roy, Xiaoqin Wang,

The ability to record well-isolated action potentials from individual neurons in naturally behaving animals is crucial for understanding neural mechanisms underlying natural behaviors. Traditional neurophysiology techniques, however, require the animal to be restrained which often restricts natural behavior. An example is the common marmoset (Callithrix jacchus), a highly vocal New ... Read more >>

J Neurosci Methods (Journal of neuroscience methods)
[2012, 203(1):28-40]

Cited: 28 times

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Vocal control by the common marmoset in the presence of interfering noise.

Sabyasachi Roy, Cory T Miller, Dane Gottsch, Xiaoqin Wang,

The natural environment is inherently noisy with acoustic interferences. It is, therefore, beneficial for a species to modify its vocal production to effectively communicate in the presence of interfering noises. Non-human primates have been traditionally considered to possess limited voluntary vocal control, but little is known about their ability to ... Read more >>

J Exp Biol (The Journal of experimental biology)
[2011, 214(Pt 21):3619-3629]

Cited: 31 times

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Intensive phase non-compliance to anti tubercular treatment in patients with HIV-TB coinfection: a hospital-based cross-sectional study.

Partha Sardar, Ayan Jha, Deeptarka Roy, Sabyasachi Roy, Pradipta Guha, Dipanjan Bandyopadhyay,

We aimed to study the prevalence and determinants of non compliance to intensive phase anti tubercular treatment (ATT) in 111 HIV-TB coinfection patients, attending the APEX Referral Center for HIV/AIDS at Medical College, Kolkata with a specially-designed, semi-structured, pre-tested questionnaire. Compliance was defined as taking ≥95% of the total scheduled ... Read more >>

J Community Health (Journal of community health)
[2010, 35(5):471-478]

Cited: 3 times

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Therapeutic effects of nandrolone and testosterone in adult male HIV patients with AIDS wasting syndrome (AWS): a randomized, double-blind, placebo-controlled trial.

Partha Sardar, Ayan Jha, Deeptarka Roy, Uddalak Majumdar, Pradipta Guha, Sabyasachi Roy, Ramtanu Banerjee, Amit Kumar Banerjee, Dipanjan Bandyopadhyay,

<h4>Purpose</h4>We aimed to compare therapeutic effects of intramuscular (IM) nandrolone decanoate and IM testosterone enanthate in male HIV patients with AIDS wasting syndrome (AWS) with placebo control.<h4>Methods</h4>In this randomized, double-blind, placebo-controlled, 12-week trial, 104 patients with AWS who satisfied our inclusion criteria were randomly allotted in a 2:2:1 ratio to ... Read more >>

HIV Clin Trials (HIV clinical trials)
[2010, 11(4):220-229]

Cited: 3 times

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Low-cost wireless neural recording system and software.

Jeffrey A Gregory, Amir Borna, Sabyasachi Roy, Xiaoqin Wang, Brian Lewandowski, Marc Schmidt, Khalil Najafi,

We describe a flexible wireless neural recording system, which is comprised of a 15-channel analog FM transmitter, digital receiver and custom user interface software for data acquisition. The analog front-end is constructed from commercial off the shelf (COTS) components and weighs 6.3g (including batteries) and is capable of transmitting over ... Read more >>

Annu Int Conf IEEE Eng Med Biol Soc (Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference)
[2009, 2009:3833-3836]

Cited: 5 times

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The relationship of age, body mass index and waist circumference with blood pressure in Bengalee Hindu male jute mill workers of Belur, West Bengal, India.

Kaushik Bose, Arnab Ghosh, Sabyasachi Roy, Somnath Gangopadhyay,

A cross-sectional study of 150 adult Bengalee Hindu male jute mill workers of Belur, a suburb of Kolkata, West Bengal, India, was undertaken to study the relationship of age, body mass index (BMI) and waist circumference (WC) with systolic (SBP), diastolic (DBP) and mean arterial (MAP) blood pressure. The mean ... Read more >>

Anthropol Anz (Anthropologischer Anzeiger; Bericht uber die biologisch-anthropologische Literatur)
[2005, 63(2):205-212]

Cited: 4 times

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Blood pressure and waist circumference: an empirical study of the effects of waist circumference on blood pressure among Bengalee male jute mill workers of Belur, West Bengal, India.

Kaushik Bose, Arnab Ghosh, Sabyasachi Roy, Somnath Gangopadhyay,

An investigation of 150 adult Bengalee Hindu male jute mill workers in Belur, a suburb of Kolkata, West Bengal, India, was conducted to study the relationship between central obesity and blood pressure. In accordance with their waist circumference measurement, the subjects were divided into two categories: centrally non-obese (CNO) and ... Read more >>

J Physiol Anthropol Appl Human Sci (Journal of physiological anthropology and applied human science)
[2003, 22(4):169-173]

Cited: 9 times

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