Full Text Journal Articles by
Author Ryan Gil

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Strategies for prediction of drug-resistant pathogens and empiric antibiotic selection in community-acquired pneumonia.

Ryan Gil, Brandon J Webb,

PURPOSE OF REVIEW:Although most patients with community-acquired pneumonia (CAP) are appropriately treated with narrow-spectrum antibiotics, predicting which patients require coverage of drug-resistant pathogens (DRP) remains a challenge. The 2019 American Thoracic Society/Infectious Diseases Society of America CAP guidelines endorse using locally validated prediction models for DRP. Here we review risk ... Read more >>

Curr Opin Pulm Med (Current opinion in pulmonary medicine)
[2020, 26(3):249-259]

Cited: 0 times

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Increased urinary osmolyte excretion indicates chronic kidney disease severity and progression rate.

Ryan B Gil, Alberto Ortiz, Maria D Sanchez-Niño, Katerina Markoska, Eva Schepers, Raymond Vanholder, Griet Glorieux, Philippe Schmitt-Kopplin, Silke S Heinzmann,

Background:Chronic kidney disease (CKD) is a recognized global health problem. While some CKD patients remain stable after initial diagnosis, others can rapidly progress towards end-stage renal disease (ESRD). This makes biomarkers capable of detecting progressive forms of CKD extremely valuable, especially in non-invasive biofluids such as urine. Screening for metabolite ... Read more >>

Nephrol. Dial. Transplant. (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[2018, 33(12):2156-2164]

Cited: 2 times

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Proteomics and Metabolomics for AKI Diagnosis.

David Marx, Jochen Metzger, Martin Pejchinovski, Ryan Bruce Gil, Maria Frantzi, Agnieszka Latosinska, Iwona Belczacka, Silke Sophie Heinzmann, Holger Husi, Jerome Zoidakis, Matthias Klingele, Stefan Herget-Rosenthal,

Acute kidney injury (AKI) is a severe and frequent condition in hospitalized patients. Currently, no efficient therapy of AKI is available. Therefore, efforts focus on early prevention and potentially early initiation of renal replacement therapy to improve the outcome in AKI. The detection of AKI in hospitalized patients implies the ... Read more >>

Semin. Nephrol. (Seminars in nephrology)
[2018, 38(1):63-87]

Cited: 4 times

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(1)H NMR-based metabolite profiling workflow to reduce inter-sample chemical shift variations in urine samples for improved biomarker discovery.

Ryan B Gil, Rainer Lehmann, Philippe Schmitt-Kopplin, Silke S Heinzmann,

Metabolite profiling of urine has seen much advancement in recent years, and its analysis by nuclear magnetic resonance (NMR) spectroscopy has become well established. However, the highly variable nature of human urine still requires improved protocols despite some standardization. In particular, diseases such as kidney disease can have a profound ... Read more >>

Anal Bioanal Chem (Analytical and bioanalytical chemistry)
[2016, 408(17):4683-4691]

Cited: 4 times

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Natural oxygenation of Champagne wine during ageing on lees: A metabolomics picture of hormesis.

Chloé Roullier-Gall, Michael Witting, Franco Moritz, Ryan B Gil, Delphine Goffette, Michel Valade, Philippe Schmitt-Kopplin, Régis D Gougeon,

The oxygenation of Champagne wine after 4 and 6 years of aging on lees in bottle was investigated by FTICR-MS and UPLC-Q-TOF-MS. Three levels of permeability were considered for the stoppers, ranging from 0.2 to 1.8 mg/L/year of oxygen transfer rate. Our results confirmed a good repeatability of ultra-high resolution ... Read more >>

Food Chem (Food chemistry)
[2016, 203:207-215]

Cited: 9 times

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Metabolic determinants of electrical failure in ex-vivo canine model of cardiac arrest: evidence for the protective role of inorganic pyrophosphate.

Junko Shibayama, Tyson G Taylor, Paul W Venable, Nathaniel L Rhodes, Ryan B Gil, Mark Warren, Adam R Wende, E Dale Abel, James Cox, Kenneth W Spitzer, Alexey V Zaitsev,

Deterioration of ventricular fibrillation (VF) into asystole or severe bradycardia (electrical failure) heralds a fatal outcome of cardiac arrest. The role of metabolism in the timing of electrical failure remains unknown.To determine metabolic factors of early electrical failure in an ex-vivo canine model of cardiac arrest (VF+global ischemia).Metabolomic screening was ... Read more >>

PLoS ONE (PloS one)
[2013, 8(3):e57821]

Cited: 5 times

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Whole-body vibration training reduces arterial stiffness, blood pressure and sympathovagal balance in young overweight/obese women.

Arturo Figueroa, Ryan Gil, Alexei Wong, Shirin Hooshmand, Song Y Park, Florence Vicil, Marcos A Sanchez-Gonzalez,

Obesity is associated with early cardiovascular dysfunction and reduced muscle strength. Whole-body vibration (WBV) training may improve arterial function and muscle strength. The effects of WBV training on arterial stiffness (brachial-ankle pulse wave velocity, baPWV), wave reflection (augmentation index, AIx), brachial systolic blood pressure (bSBP), aortic systolic blood pressure (aSBP), ... Read more >>

Hypertens. Res. (Hypertension research : official journal of the Japanese Society of Hypertension)
[2012, 35(6):667-672]

Cited: 40 times

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Passive vibration on the legs reduces peripheral and systemic arterial stiffness.

Alexei Wong, Marcos A Sanchez-Gonzalez, Ryan Gil, Florence Vicil, Song Young Park, Arturo Figueroa,

Hypertens. Res. (Hypertension research : official journal of the Japanese Society of Hypertension)
[2012, 35(1):126-127]

Cited: 7 times

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Whole-body vibration attenuates the increase in leg arterial stiffness and aortic systolic blood pressure during post-exercise muscle ischemia.

Arturo Figueroa, Ryan Gil, Marcos A Sanchez-Gonzalez,

Exercise with whole-body vibration (WBV) decreases brachial-ankle pulse wave velocity (baPWV), a marker of systemic arterial stiffness. To examine the effect of WBV on arterial responses, 12 young men underwent three experimental trials: (1) no-exercise control (CON), (2) static squat with WBV, and (3) static squat without WBV (no-WBV). Bilateral ... Read more >>

Eur. J. Appl. Physiol. (European journal of applied physiology)
[2011, 111(7):1261-1268]

Cited: 9 times

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