Full Text Journal Articles by
Author Ruxandra Draghia Akli

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Accelerating Coronavirus Disease 2019 Therapeutic Interventions and Vaccines-Selecting Compounds for Clinical Evaluation in Coronavirus Disease 2019 Clinical Trials.

Timothy G Buchman, Ruxandra Draghia-Akli, Stacey J Adam, Neil R Aggarwal, Joshua P Fessel, Elizabeth S Higgs, Joseph P Menetski, Sarah W Read, Eric A Hughes, ,

Given the urgent need for coronavirus disease 2019 therapeutics, early in the pandemic the Accelerating Coronavirus Disease 2019 Therapeutic Interventions and Vaccines (ACTIV) public-private partnership rapidly designed a unique therapeutic agent intake and assessment process for candidate treatments of coronavirus disease 2019. These treatments included antivirals, immune modulators, severe acute ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(11):1963-1973]

Cited: 0 times

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Future of Rare Diseases Research 2017-2027: An IRDiRC Perspective.

Christopher P Austin, Christine M Cutillo, Lilian P L Lau, Anneliene H Jonker, Ana Rath, Daria Julkowska, David Thomson, Sharon F Terry, Béatrice de Montleau, Diego Ardigò, Virginie Hivert, Kym M Boycott, Gareth Baynam, Petra Kaufmann, Domenica Taruscio, Hanns Lochmüller, Makoto Suematsu, Carlo Incerti, Ruxandra Draghia-Akli, Irene Norstedt, Lu Wang, Hugh J S Dawkins, ,

Clin Transl Sci (Clinical and translational science)
[2018, 11(1):21-27]

Cited: 43 times

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Progress in Rare Diseases Research 2010-2016: An IRDiRC Perspective.

Hugh J S Dawkins, Ruxandra Draghia-Akli, Paul Lasko, Lilian P L Lau, Anneliene H Jonker, Christine M Cutillo, Ana Rath, Kym M Boycott, Gareth Baynam, Hanns Lochmüller, Petra Kaufmann, Yann Le Cam, Virginie Hivert, Christopher P Austin, ,

Clin Transl Sci (Clinical and translational science)
[2018, 11(1):11-20]

Cited: 36 times

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Enabling personalized medicine in Europe by the European Commission's funding activities.

Elmar Nimmesgern, Irene Norstedt, Ruxandra Draghia-Akli,

Personalized medicine (PM) is an emerging approach to prevention, diagnosis, treatment and care. It helps to address the challenge of the aging of the population, an increase in chronic disease and increasing healthcare costs. The EU is developing policies to move toward PM. This is underpinned by a sustained and ... Read more >>

Per Med (Personalized medicine)
[2017, 14(4):355-365]

Cited: 4 times

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European Union research in support of environment and health: Building scientific evidence base for policy.

Tuomo Karjalainen, Arnd Hoeveler, Ruxandra Draghia-Akli,

Opinion polls show that the European Union citizens are increasingly concerned about the impact of environmental factors on their health. In order to respond and provide solid scientific evidence for the numerous policies related to the protection of human health and the environment managed at the Union level, the European ... Read more >>

Environ Int (Environment international)
[2017, 103:51-60]

Cited: 2 times

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Understanding the brain through large, multidisciplinary research initiatives.

Gianluca Quaglio, Maurizio Corbetta, Theodoros Karapiperis, Katrin Amunts, Walter Koroshetz, Tetsuo Yamamori, Ruxandra Draghia-Akli,

Lancet Neurol (The Lancet. Neurology)
[2017, 16(3):183-184]

Cited: 1 time

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New Vaccines against Epidemic Infectious Diseases.

John-Arne Røttingen, Dimitrios Gouglas, Mark Feinberg, Stanley Plotkin, Krishnaswamy V Raghavan, Andrew Witty, Ruxandra Draghia-Akli, Paul Stoffels, Peter Piot,

N Engl J Med (The New England journal of medicine)
[2017, 376(7):610-613]

Cited: 32 times

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Improved Diagnosis and Care for Rare Diseases through Implementation of Precision Public Health Framework.

Gareth Baynam, Faye Bowman, Karla Lister, Caroline E Walker, Nicholas Pachter, Jack Goldblatt, Kym M Boycott, William A Gahl, Kenjiro Kosaki, Takeya Adachi, Ken Ishii, Trinity Mahede, Fiona McKenzie, Sharron Townshend, Jennie Slee, Cathy Kiraly-Borri, Anand Vasudevan, Anne Hawkins, Stephanie Broley, Lyn Schofield, Hedwig Verhoef, Tudor Groza, Andreas Zankl, Peter N Robinson, Melissa Haendel, Michael Brudno, John S Mattick, Marcel E Dinger, Tony Roscioli, Mark J Cowley, Annie Olry, Marc Hanauer, Fowzan S Alkuraya, Domenica Taruscio, Manuel Posada de la Paz, Hanns Lochmüller, Kate Bushby, Rachel Thompson, Victoria Hedley, Paul Lasko, Kym Mina, John Beilby, Cynthia Tifft, Mark Davis, Nigel G Laing, Daria Julkowska, Yann Le Cam, Sharon F Terry, Petra Kaufmann, Iiro Eerola, Irene Norstedt, Ana Rath, Makoto Suematsu, Stephen C Groft, Christopher P Austin, Ruxandra Draghia-Akli, Tarun S Weeramanthri, Caron Molster, Hugh J S Dawkins,

Public health relies on technologies to produce and analyse data, as well as effectively develop and implement policies and practices. An example is the public health practice of epidemiology, which relies on computational technology to monitor the health status of populations, identify disadvantaged or at risk population groups and thereby ... Read more >>

Adv Exp Med Biol (Advances in experimental medicine and biology)
[2017, 1031:55-94]

Cited: 6 times

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European strategy for vaccine development against infectious diseases.

Line Matthiessen, Hannu Lång, Maria Klimathianaki, Finnian Hanrahan, Barbara Kerstiëns, Alessandra Martini, Ruxandra Draghia-Akli,

Immunisation efforts save millions of lives every year, but vaccines hold the potential to deliver even greater health benefits for mankind. Vaccine research and development is highly complex, and it requires concerted public funding efforts to support. In this paper we discuss EU funding priorities and the resulting recent advancements ... Read more >>

Vaccine (Vaccine)
[2017, 35 Suppl 1:A20-A23]

Cited: 2 times

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The need for innovation and implementation research for maternal and newborn health.

Evelyn Depoortere, Zoë Matthews, Andrea Nove, Finnian Hanrahan, Barbara Kerstiëns, Line Matthiessen, Marleen Temmerman, Ruxandra Draghia-Akli, ,

Lancet (Lancet (London, England))
[2016, 388(10052):1374]

Cited: 3 times

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Increased momentum in antimicrobial resistance research.

Line Matthiessen, Richard Bergström, Shiva Dustdar, Pierre Meulien, Ruxandra Draghia-Akli,

Lancet (Lancet (London, England))
[2016, 388(10047):865]

Cited: 1 time

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Chronic respiratory diseases and lung cancer research: a perspective from the European Union.

Adoración Navarro-Torné, María Vidal, Dominika K Trzaska, Lara Passante, Aldo Crisafulli, Hannu Laang, Jan-Willem van de Loo, Karim Berkouk, Ruxandra Draghia-Akli,

Eur Respir J (The European respiratory journal)
[2015, 46(5):1270-1280]

Cited: 6 times

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Introduction: Gene Therapy and Gene Transfer Projects of the 7th Framework Programme for Research and Technological Development of the European Union (Second Part).

David Gancberg, Arnd Hoeveler, Ruxandra Draghia-Akli,

Hum Gene Ther Clin Dev (Human gene therapy. Clinical development)
[2015, 26(2):77]

Cited: 5 times

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Better safe than sorry: ethics review in European Union-funded health research.

Ruxandra Draghia-Akli, Arnd Hoeveler, Peter Löffler, Joana Namorado,

Public scrutiny and the increasing number of projects addressing later stages of the research and innovation process announced the need for an enhanced attention to be paid to identify and address ethics concerns. Ex-ante ethics review as implemented in EU-funded health research and a proactive ethics management are a genuinely ... Read more >>

Stem Cells Dev (Stem cells and development)
[2014, 23 Suppl 1:47-50]

Cited: 0 times

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Opportunities for vaccine research in Europe.

David Gancberg, Arnd Hoeveler, Alessandra Martini, Ruxandra Draghia-Akli,

Hum Vaccin Immunother (Human vaccines & immunotherapeutics)
[2015, 11(8):1917-1920]

Cited: 1 time

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Introduction: gene and cell therapy projects of the seventh framework program.

David Gancberg, Irene Norstedt, Ruxandra Draghia-Akli,

Hum Gene Ther Clin Dev (Human gene therapy. Clinical development)
[2014, 25(2):51]

Cited: 2 times

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Gene and cell therapy funding opportunities in horizon 2020: an overview for 2014-2015.

David Gancberg, Ruxandra Draghia-Akli,

Hum Gene Ther (Human gene therapy)
[2014, 25(3):175-177]

Cited: 4 times

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Toward an international initiative for traumatic brain injury research.

Patrizia Tosetti, Ramona R Hicks, Elizabeth Theriault, Anthony Phillips, Walter Koroshetz, Ruxandra Draghia-Akli, ,

The European Commission (EC) and the National Institutes of Health (NIH) jointly sponsored a workshop on October 18-20, 2011 in Brussels to discuss the feasibility and benefits of an international collaboration in the field of traumatic brain injury (TBI) research. The workshop brought together scientists, clinicians, patients, and industry representatives ... Read more >>

J Neurotrauma (Journal of neurotrauma)
[2013, 30(14):1211-1222]

Cited: 38 times

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A database on global health research in Africa.

Francis Collins, Alain Beaudet, Ruxandra Draghia-Akli, Peter Gruss, John Savill, André Syrota, Alice Dautry, Mats Ulfendahl, Mark Walport, James Onken, Roger I Glass,

Lancet Glob Health (The Lancet. Global health)
[2013, 1(2):e64-e65]

Cited: 9 times

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Effects of administration of two growth hormone-releasing hormone plasmids to gilts on sow and litter performance for the subsequent three gestations.

Patricia A Brown, Amir S Khan, Ruxandra Draghia-Akli, Melissa A Pope, Angela M Bodles-Brakhop, Douglas R Kern,

<h4>Objective</h4>To determine whether a novel optimized plasmid carrying the porcine growth hormone-releasing hormone (GHRH) wild-type cDNA administered at a lower dose was as effective at eliciting physiologic responses as a commercial GHRH plasmid approved for use in Australia.<h4>Animals</h4>134 gilts.<h4>Procedures</h4>Estrus was synchronized and gilts were bred. Pregnant gilts were assigned to ... Read more >>

Am J Vet Res (American journal of veterinary research)
[2012, 73(9):1428-1434]

Cited: 3 times

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European Union support of gene therapy research: a success story.

David Gancberg, Charles Kessler, Arnd Hoeveler, Ruxandra Draghia-Akli,

Mol Ther (Molecular therapy : the journal of the American Society of Gene Therapy)
[2012, 20(12):2191-2193]

Cited: 1 time

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Enabling personalized medicine in Europe: a look at the European Commission's funding activities in the field of personalized medicine research.

Ruxandra Draghia-Akli,

The potential benefits that personalized medicine approaches can bring to healthcare are discussed with much interest throughout the EU. This novel approach is based on a better understanding of the molecular mechanisms of health and disease and it has now begun to show results. There is, however, a long way ... Read more >>

Per Med (Personalized medicine)
[2012, 9(2):151-155]

Cited: 2 times

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Emphasising the European Union's Commitment to Cancer Research: a helicopter view of the Seventh Framework Programme for Research and Technological Development.

Jan-Willem van de Loo, Dominika Trzaska, Karim Berkouk, Maria Vidal, Ruxandra Draghia-Akli,

Oncologist (The oncologist)
[2012, 17(10):e26-32]

Cited: 2 times

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IMI moves forward.

Rudolf Strohmeier, Ruxandra Draghia-Akli, Andrzej Rys, Pedro Ortun Silvan, Theodius Lennon, Carlo Incerti, Richard Bergström, Salahdine Chibout, Roch Doliveux, Peter Hongaard Andersen,

Nat Biotechnol (Nature biotechnology)
[2011, 29(8):689-90; reply 690]

Cited: 0 times

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The selection of experts evaluating health projects for the EU Sixth Framework Program.

Gianluca Quaglio, Vincenzo Guardabasso, Ole F Olesen, Ruxandra Draghia-Akli,

AIM: The Framework Programmes for Research and Technological Development (FP) are the European Union's funding programmes for research in Europe. The study analyses the features of external experts involved in evaluating the research proposals in FP6 (years 2003-2006) in the area of Life Sciences. SUBJECTS AND METHODS: Experts were ... Read more >>

Z Gesundh Wiss (Zeitschrift fur Gesundheitswissenschaften = Journal of public health)
[2011, 19(5):445-452]

Cited: 1 time

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