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Author Rupesh Raina

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TEMPORARY REMOVAL: Genetic and Sporadic Renal Cystic Diseases During the Perinatal and Neonatal Period: Core Curriculum 2021.

Rupesh Raina, Ronith Chakraborty, Sidharth K Sethi, Deepak Kumar, Kelly Gibson, Carsten Bergmann,

The publisher regrets that this article has been temporarily removed as it was mistakenly published online early. The article will be reinstated with the corrected proof as soon as possible. The full Elsevier Policy on Article Withdrawal can be found at: https://www.elsevier.com/about/our-business/policies/article-withdrawal. ... Read more >>

Am J Kidney Dis (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2021, :]

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Late first acute rejection in pediatric kidney transplantation: A North American Pediatric Renal Trials and Collaborative Studies special study.

Kevin T Barton, Khalif Halani, Shirley Galbiati, Raja Dandamudi, Stanley Paul Hmiel, Vikas R Dharnidharka, ,

Rates of early AR in pediatric kidney transplantation have declined in every era but the most recent NAPRTCS cohort has shown an increase in late first AR rates. We hypothesized this was due to an increased proportion of deceased donor utilization and early steroid taper utilization. Using the NAPRTCS database, ... Read more >>

Pediatr Transplant (Pediatric transplantation)
[2020, :e13953]

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Acute Kidney Injury Associated With Urinary Stone Disease in Children and Young Adults Presenting to a Pediatric Emergency Department.

Nicholas Farris, Rupesh Raina, Abhishek Tibrewal, Miraides Brown, Maria Colvis, Andrew Schwaderer, Kirsten Kusumi,

<b>Background:</b> Acute kidney injury (AKI) due to urinary stone disease (USD) is rare in adults; AKI rates in children with USD may be higher, and emerging data links stones to chronic kidney disease (CKD) development in adults. <b>Methods:</b> This study is a retrospective analysis of USD patients at a single ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:591520]

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Diversity of Phenotype and Genetic Etiology of 23 Cystinuria Saudi Patients: A Retrospective Study.

Malak Alghamdi, Khalid A Alhasan, Areej Taha Elawad, Suha Salim, Marwa Abdelhakim, Marwan Nashabat, Rupesh Raina, Jameela Kari, Majid Alfadhel,

<b>Background:</b> Cystinuria is an inborn error of metabolism that manifests with renal stones due to defective renal epithelial cell transport of cystine which resulted from pathogenic variants in the <i>SLC3A1</i> and/or <i>SLC7A9</i> genes. Among nephrolithiasis diseases, cystinuria is potentially treatable, and further stone formation may be preventable. We report 23 ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:569389]

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Evolution and change in paradigm of hemodialysis in children: a systematic review.

Rahul Chanchlani, Claire Young, Aisha Farooq, Stephanie Sanger, Sidharth Sethi, Ronith Chakraborty, Abhishek Tibrewal, Rupesh Raina,

<h4>Background</h4>There are similarities in hemodialysis (HD) between adults and children and also unique pediatric aspects. In this systematic review, we evaluated the existing HD literature, including vascular access, indications, parameters, and outcomes as a reflection on real-life HD practices.<h4>Methods</h4>Medline, Embase, CINAHL, Web of Science, and Cochrane Library were systematically searched ... Read more >>

Pediatr Nephrol (Pediatric nephrology (Berlin, Germany))
[2020, :]

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AGREEing on the Management of Idiopathic Steroid-sensitive Nephrotic Syndrome in Children: A Systematic Review of Clinical Practice Guidelines

Khalid Abdulaziz Alhasan, Reem Al Khalifah, Majed Aloufi, Weiam Almaiman, Muddathir Hamad, Naif Fahad Abdulmajeed, Abdullah Al Salloum, Jameela Kari, Muneera AlJelaify, Rolan Bassrawi, Turki Al Hussain, Adi Alherbish, Abdulhadi Al Talhi, Mohamad-Hani Temsah, Sidharth Kumar Sethi, Rupesh Raina, Reny Joseph, Yasser Sami Amer,

<h4>Background: </h4> Nephrotic syndrome is the most common kidney disease in children worldwide. Our aim was to critically appraise the quality of recent Clinical Practice Guidelines (CPGs) for idiopathic steroid-sensitive nephrotic syndrome (SSNS) in children in addition to summarize and compare their recommendations. <h4>Methods: </h4> Systematic review of CPGs. We ... Read more >>

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A rare complication of pauci-immune crescentic glomerulonephritis in a child: Questions.

Sidharth Kumar Sethi, Abhyuday Rana, Shyam Bihari Bansal, Alka Rana, Dinesh Kumar Yadav, Kritika Soni, Marie-Agnès Dragon-Durey, Rupesh Raina, Vijay Kher,

Pediatr Nephrol (Pediatric nephrology (Berlin, Germany))
[2020, :]

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A rare complication of pauci-immune crescentic glomerulonephritis in a child: Answers.

Sidharth Kumar Sethi, Abhyuday Rana, Shyam Bihari Bansal, Alka Rana, Dinesh Kumar Yadav, Kritika Soni, Marie-Agnès Dragon-Durey, Rupesh Raina, Vijay Kher,

Pediatr Nephrol (Pediatric nephrology (Berlin, Germany))
[2020, :]

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Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes.

George L Bakris, Rajiv Agarwal, Stefan D Anker, Bertram Pitt, Luis M Ruilope, Peter Rossing, Peter Kolkhof, Christina Nowack, Patrick Schloemer, Amer Joseph, Gerasimos Filippatos, ,

<h4>Background</h4>Finerenone, a nonsteroidal, selective mineralocorticoid receptor antagonist, reduced albuminuria in short-term trials involving patients with chronic kidney disease (CKD) and type 2 diabetes. However, its long-term effects on kidney and cardiovascular outcomes are unknown.<h4>Methods</h4>In this double-blind trial, we randomly assigned 5734 patients with CKD and type 2 diabetes in a ... Read more >>

N Engl J Med (The New England journal of medicine)
[2020, 383(23):2219-2229]

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Challenges of long-term vascular access in pediatric hemodialysis: Recommendations for practitioners.

Rupesh Raina, Hirva Joshi, Ronith Chakraborty, Sidharth Kumar Sethi,

Kidney transplantation is the preferred treatment of end-stage renal disease in children. However, time to transplant varies, making a well-functioning long-term vascular access essential for performing hemodialysis efficiently and without disruption until a kidney becomes available. However, establishing long-term vascular access in pediatric patients can present distinct challenges due to ... Read more >>

Hemodial Int (Hemodialysis international. International Symposium on Home Hemodialysis)
[2021, 25(1):3-11]

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Hypertensive Crisis in Pediatric Patients: An Overview.

Rupesh Raina, Zubin Mahajan, Aditya Sharma, Ronith Chakraborty, Sarisha Mahajan, Sidharth K Sethi, Gaurav Kapur, David Kaelber,

Hypertensive crisis can be a source of morbidity and mortality in the pediatric population. While the epidemiology has been difficult to pinpoint, it is well-known that secondary causes of pediatric hypertension contribute to a greater incidence of hypertensive crisis in pediatrics. Hypertensive crisis may manifest with non-specific symptoms as well ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:588911]

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Cerebral venous sinus thrombosis in pediatric nephrotic syndrome.

Sidharth Kumar Sethi, Vivek Sharma, Ronith Chakraborty, Vijay Kher, Rupesh Raina,

Kidney Int (Kidney international)
[2020, 98(4):1056]

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Changing the terminology from kidney replacement therapy to kidney support therapy.

Rupesh Raina, Hirva Joshi, Ronith Chakraborty,

Kidney replacement therapy (KRT) is a common supportive treatment for renal dysfunction, especially acute kidney injury. However, critically ill or immunosuppressed patients with renal dysfunction often have dysfunction in other organs as well. To improve patient outcomes, clinicians began to initiate kidney replacement therapy in situations where nonrenal conditions may ... Read more >>

Ther Apher Dial (Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy)
[2020, :]

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Renal Manifestations of Tuberous Sclerosis Complex.

Nikhil Nair, Ronith Chakraborty, Zubin Mahajan, Aditya Sharma, Sidharth K Sethi, Rupesh Raina,

Tuberous sclerosis complex (TSC) is a genetic condition caused by a mutation in either the <i>TSC1</i> or <i>TSC2</i> gene. Disruption of either of these genes leads to impaired production of hamartin or tuberin proteins, leading to the manifestation of skin lesions, tumors, and seizures. TSC can manifest in multiple organ ... Read more >>

J Kidney Cancer VHL (Journal of kidney cancer and VHL)
[2020, 7(3):5-19]

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Development of acute kidney injury following pediatric cardiac surgery.

Aditya Sharma, Ronith Chakraborty, Katyayini Sharma, Sidharth K Sethi, Rupesh Raina,

Acute kidney injury (AKI) in the pediatric population is a relatively common phenomenon. Specifically, AKI has been found in increasing numbers within the pediatric population following cardiac surgery, with up to 43% of pediatric patients developing AKI post-cardiac surgery. However, recent advances have allowed for the identification of risk factors. ... Read more >>

Kidney Res Clin Pract (Kidney research and clinical practice)
[2020, 39(3):259-268]

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Uncommon cause of fever in a child with steroid-dependent nephrotic syndrome.

Sidharth Kumar Sethi, Shyam Bansal, Ronith Chakraborty, Rahul Jain, Nikita Wadhwani, Rupesh Raina,

<h4>Background</h4>Children with nephrotic syndrome are vulnerable to developing infections due to a state of relative immunodeficiency, malnourishment, and use of immunosuppression. Case characteristics: We herein report the case of a 3-year-old child with steroid-dependent nephrotic syndrome who presented to us with fever of unknown origin.<h4>Observation</h4>The child was found to have ... Read more >>

Clin Nephrol Case Stud (Clinical nephrology. Case studies)
[2020, 8:49-52]

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Establishing core outcome domains in pediatric kidney disease: report of the Standardized Outcomes in Nephrology-Children and Adolescents (SONG-KIDS) consensus workshops.

Camilla S Hanson, Jonathan C Craig, Charlotte Logeman, Aditi Sinha, Allison Dart, Allison A Eddy, Chandana Guha, Debbie S Gipson, Detlef Bockenhauer, Hui-Kim Yap, Jaap Groothoff, Michael Zappitelli, Nicholas J A Webb, Stephen I Alexander, Susan L Furth, Susan Samuel, Alicia Neu, Andrea K Viecelli, Angela Ju, Ankit Sharma, Eric H Au, Hailey Desmond, Jenny I Shen, Karine E Manera, Karolis Azukaitis, Louese Dunn, Simon A Carter, Talia Gutman, Yeoungjee Cho, Amanda Walker, Anna Francis, Cheryl Sanchez-Kazi, Joshua Kausman, Meghan Pearl, Nadine Benador, Shobha Sahney, Allison Tong, ,

Trials in children with chronic kidney disease do not consistently report outcomes that are critically important to patients and caregivers. This can diminish the relevance and reliability of evidence for decision making, limiting the implementation of results into practice and policy. As part of the Standardized Outcomes in Nephrology-Children and ... Read more >>

Kidney Int (Kidney international)
[2020, 98(3):553-565]

Cited: 1 time

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Kidney Replacement Therapy in COVID-19 Induced Kidney Failure and Septic Shock: A Pediatric Continuous Renal Replacement Therapy [PCRRT] Position on Emergency Preparedness With Resource Allocation.

Rupesh Raina, Ronith Chakraborty, Sidharth Kumar Sethi, Timothy Bunchman,

The recent worldwide pandemic of COVID-19 has had a detrimental worldwide impact on people of all ages. Although data from China and the United States indicate that pediatric cases often have a mild course and are less severe in comparison to adults, there have been several cases of kidney failure ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:413]

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ACTH Treatment for Management of Nephrotic Syndrome: A Systematic Review and Reappraisal.

Ronith Chakraborty, Arul Mehta, Nikhil Nair, Lena Nemer, Rahul Jain, Hirva Joshi, Rupesh Raina,

<h4>Background</h4>In recent years, the use of adrenocorticotropic hormone (ACTH) therapy for treatment of proteinuria due to nephrotic syndrome (NS) has been heavily explored. ACTH therapy, which comes in the natural (H. P. Acthar Gel) or synthetic (tetracosactide) form, has resulted in remission in patients with immunosuppressive and steroid-resistant NS. However, ... Read more >>

Int J Nephrol (International journal of nephrology)
[2020, 2020:2597079]

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Low hemoglobin levels are independently associated with neonatal acute kidney injury: a report from the AWAKEN Study Group.

Arwa Nada, David Askenazi, Louis J Boohaker, Linzi Li, John D Mahan, Jennifer Charlton, Russell L Griffin, ,

<h4>Background</h4>Studies in adults showed a relationship between low hemoglobin (Hb) and acute kidney injury (AKI). We performed this study to evaluate this association in newborns.<h4>Methods</h4>We evaluated 1891 newborns from the Assessment of Worldwide AKI Epidemiology in Neonates (AWAKEN) database. We evaluated the associations for the entire cohort and 3 gestational ... Read more >>

Pediatr Res (Pediatric research)
[2020, :]

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Mystery of black urine: alkaptonuria.

Sidharth Kumar Sethi, Rupesh Raina, Ronith Chakraborty, Vijay Kher,

Kidney Int (Kidney international)
[2020, 97(6):1303]

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Association of pulse pressure, pulse pressure index, and ambulatory arterial stiffness index with kidney function in a cross-sectional pediatric chronic kidney disease cohort from the CKiD study.

Rupesh Raina, Shyam Polaconda, Nikhil Nair, Ronith Chakraborty, Sidharth Sethi, Vinod Krishnappa, Gaurav Kapur, Maroun Mhanna, Kirsten Kusumi,

The morbidity and mortality of adult and pediatric chronic kidney disease (CKD) and end-stage renal disease (ESRD) populations are mainly driven by cardiovascular disease (CVD). Improving CVD outcomes focuses on risk assessment of factors including diastolic blood pressure (DBP), systolic blood pressure (SBP), left ventricular mass index (LVMI), pulse pressure ... Read more >>

J Clin Hypertens (Greenwich) (Journal of clinical hypertension (Greenwich, Conn.))
[2020, 22(6):1059-1069]

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Autosomal-dominant polycystic kidney disease: tolvaptan use in adolescents and young adults with rapid progression.

Rupesh Raina, Ronith Chakraborty, Meredith E DeCoy, Timothy Kline,

BACKGROUND:The phase 3 Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and Its Outcomes (TEMPO 3:4) clinical trial demonstrated the beneficial effect of tolvaptan on kidney growth and function in subjects aged 18-50 years over a 3-year period. However, it did not specifically assess the use ... Read more >>

Pediatr Res (Pediatric research)
[2020, :]

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Challenges of Vascular Access in the Pediatric Population.

Rupesh Raina, Aliza Mittal, Sidharth Kumar Sethi, Ronith Chakraborty,

The incidence and prevalence of renal replacement therapy has continued to increase in the pediatric population. Recent data have shown that hemodialysis was the most frequently used dialysis modality, especially in pediatric ESRD patients (age 0-21 years). A well-functioning vascular access is required for effective hemodialysis and choosing the best vascular ... Read more >>

Adv Chronic Kidney Dis (Advances in chronic kidney disease)
[2020, 27(3):268-275]

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Consensus guidelines for management of hyperammonaemia in paediatric patients receiving continuous kidney replacement therapy.

Rupesh Raina, Jirair K Bedoyan, Uta Lichter-Konecki, Philippe Jouvet, Stefano Picca, Nicholas Ah Mew, Marcel C Machado, Ronith Chakraborty, Meghana Vemuganti, Manpreet K Grewal, Timothy Bunchman, Sidharth Kumar Sethi, Vinod Krishnappa, Mignon McCulloch, Khalid Alhasan, Arvind Bagga, Rajit K Basu, Franz Schaefer, Guido Filler, Bradley A Warady,

Hyperammonaemia in children can lead to grave consequences in the form of cerebral oedema, severe neurological impairment and even death. In infants and children, common causes of hyperammonaemia include urea cycle disorders or organic acidaemias. Few studies have assessed the role of extracorporeal therapies in the management of hyperammonaemia in ... Read more >>

Nat Rev Nephrol (Nature reviews. Nephrology)
[2020, 16(8):471-482]

Cited: 2 times

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