Full Text Journal Articles by
Author Rulin Qian

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Up-regulation of microRNA miR-101-3p enhances sensitivity to cisplatin via regulation of small interfering RNA (siRNA) Anti-human AGT4D and autophagy in non-small-cell lung carcinoma (NSCLC).

Dong Cui, Yu Feng, Rulin Qian,

The emergence of drug resistance hinders the treatment of malignant tumors, and autophagy plays an important role in tumor chemotherapy resistance. However, its mechanism in non-small cell lung cancer (NSCLC) has not been well-researched. We aim to investigate the role of miR-101-3p in cisplatin-resistant via regulation of autophagy-related protein 4D ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):8435-8446]

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Video-assisted mediastinoscopic and laparoscopic transhiatal esophagectomy for esophageal cancer.

Kefeng Shi, Rulin Qian, Xiao Zhang, Zhe Jin, Tao Lin, Baoping Lang, Guolei Wang, Dong Cui, Binbin Zhang, Xionghuai Hua,

<h4>Background</h4>Mediastinoscopy was originally applied for lymph node biopsy and mediastinal tumor resection. Improved video imaging with spreadable working channels enabled mediastinoscopy for inspection and tissue biopsy in the superior mediastinum but it is rarely used in minimally invasive esophageal cancer surgery. In this prospective trial, the practicability and security of ... Read more >>

Surg Endosc (Surgical endoscopy)
[2021, :]

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Long non-coding RNA TRPM2-AS sponges microRNA-138-5p to activate epidermal growth factor receptor and PI3K/AKT signaling in non-small cell lung cancer.

Dong Cui, Yu Feng, Kefeng Shi, Huimin Zhang, Rulin Qian,

<h4>Background</h4>Long non-coding RNAs (lncRNAs) can play pivotal roles in tumor progression by acting as microRNA (miRNA) sponges. This study aimed to investigate the association of a novel lncRNA, TRPM2-AS, with the miR-138-5p/EGFR axis in the development of non-small cell lung cancer (NSCLC).<h4>Methods</h4>Sixty NSCLC tissues and paired adjacent non-tumor tissues were ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2020, 8(20):1313]

Cited: 4 times

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Effectiveness and safety of bovine pericardium patch repair for cervical anastomotic leakage after oesophagectomy for cancer.

Xionghuai Hua, Rulin Qian, Kefeng Shi, Xiufeng Wei, Heng Zhang, Ge Qu, Maolin Chen, Binbin Zhang,

Background:The objective of this study is to evaluate the effectiveness and safety of bovine pericardium patch (BPP) repair for cervical anastomotic leakage after esophageal squamous cancer. Methods:Intractable cervical anastomotic leakage developed in 7 patients of esophageal squamous cell carcinoma undergoing cervical anastomosis. These patients received the BPP repair. The necrotic ... Read more >>

J Thorac Dis (Journal of thoracic disease)
[2019, 11(9):3808-3813]

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Rotational Rheology of Bovine Serum Albumin Solutions: Confounding Effects of Impurities, Mechanistic Considerations and Potential Implications on Protein Formulation Development.

Jian Hua Gu, Rulin Qian, Robert Chou, Pavel V Bondarenko, Merrill Goldenberg,

PURPOSE:To show and rationalize the confounding effects on the rotational/oscillatory rheology of surface active impurities in commercial protein formulations such as bovine serum albumin, BSA. METHODS:Bulk and interfacial rotational/oscillatory rheology were used to study the viscosity, complex viscosity, storage/elastic modulus, G' and loss/viscous modulus, G", as a function of time ... Read more >>

Pharm Res (Pharmaceutical research)
[2018, 35(8):157]

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The expression of SALL4 is significantly associated with EGFR, but not KRAS or EML4-ALK mutations in lung cancer.

Xiangbo Jia, Rulin Qian, Binbin Zhang, Song Zhao,

<h4>Background</h4>Lung cancer is the leading cause of cancer-related deaths worldwide; unfortunately, its prognosis is still very poor. Therefore, developing the target molecular is very important for lung cancer diagnosis and treatment, especially in the early stage. With this in view, spalt-like transcription factor 4 (<i>SALL4</i>) is considered a potential biomarker ... Read more >>

J Thorac Dis (Journal of thoracic disease)
[2016, 8(10):2682-2688]

Cited: 2 times

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Clinical significance of nucleostemin and proliferating cell nuclear antigen protein expression in non-small cell lung cancer.

Xiangyang Li, Xiaohui Liu, Dong Cui, Xiao Wu, Rulin Qian,

<h4>Purpose</h4>To investigate the expression and significance of the expression of nucleostemin (NS) and proliferating cell nuclear antigen (PCNA) protein in non-small cell lung cancer (NSCLC).<h4>Methods</h4>Immunohistochemistry (streptavidin-peroxidase method) was used to detect NS and PCNA expression in 53 NSCLC samples and 15 normal lung samples.<h4>Results</h4>NS protein expression was detected in 54.7% ... Read more >>

J BUON (Journal of B.U.ON. : official journal of the Balkan Union of Oncology)
[2015, 20(4):1088-1093]

Cited: 3 times

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