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Author Ruediger C Braun Dullaeus

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Inhibition of Platelet Aggregation After Coronary Stenting in Patients Receiving Oral Anticoagulation.

Conrad Genz, Ruediger C Braun-Dullaeus,

<h4>Background</h4>Approximately 18% of patients with atrial fibrillation undergo a percutaneous coronary intervention (PCI) to treat coronary heart disease. Pharmacological anticoagulation in patients with atrial fibrillation and PCI involves a trade-off of potential ischemic and hemorrhagic complications.<h4>Methods</h4>This review is based on pertinent publications that were retrieved by a selective literature search, ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(Forthcoming):]

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Predictors and prognosis of right ventricular function in pulmonary hypertension due to heart failure with reduced ejection fraction.

Alexander Schmeißer, Thomas Rauwolf, Thomas Groscheck, Katharina Fischbach, Siegfried Kropf, Blerim Luani, Ivan Tanev, Michael Hansen, Saskia Meißler, Kerstin Schäfer, Paul Steendijk, Ruediger C Braun-Dullaeus,

<h4>Aims</h4>Failure of right ventricular (RV) function worsens outcome in pulmonary hypertension (PH). The adaptation of RV contractility to afterload, the RV-pulmonary artery (PA) coupling, is defined by the ratio of RV end-systolic to PA elastances (Ees/Ea). Using pressure-volume loop (PV-L) technique we aimed to identify an Ees/Ea cut-off predictive for ... Read more >>

ESC Heart Fail (ESC heart failure)
[2021, :]

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Prognostic impact of acute pulmonary triggers in patients with takotsubo syndrome: new insights from the International Takotsubo Registry.

Ken Kato, Victoria L Cammann, L Christian Napp, Konrad A Szawan, Jozef Micek, Sara Dreiding, Rena A Levinson, Vanya Petkova, Michael Würdinger, Alexandru Patrascu, Rafael Sumalinog, Sebastiano Gili, Christian F Clarenbach, Malcolm Kohler, Manfred Wischnewsky, Rodolfo Citro, Carmine Vecchione, Eduardo Bossone, Michael Neuhaus, Jennifer Franke, Benjamin Meder, Milosz Jaguszewski, Michel Noutsias, Maike Knorr, Susanne Heiner, Fabrizio D'Ascenzo, Wolfgang Dichtl, Christof Burgdorf, Behrouz Kherad, Carsten Tschöpe, Annahita Sarcon, Jerold Shinbane, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Mahir Karakas, Wolfgang Koenig, Alexander Pott, Philippe Meyer, Marco Roffi, Adrian Banning, Mathias Wolfrum, Florim Cuculi, Richard Kobza, Thomas A Fischer, Tuija Vasankari, K E Juhani Airaksinen, Monika Budnik, Rafal Dworakowski, Philip MacCarthy, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Christina Chan, Paul Bridgman, Daniel Beug, Clément Delmas, Olivier Lairez, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, Ibrahim El-Battrawy, Ibrahim Akin, Martin Kozel, Petr Tousek, David E Winchester, Jan Galuszka, Christian Ukena, Gregor Poglajen, Pedro Carrilho-Ferreira, Christian Hauck, Carla Paolini, Claudio Bilato, Masanori Sano, Iwao Ishibashi, Masayuki Takahara, Toshiharu Himi, Yoshio Kobayashi, Abhiram Prasad, Charanjit S Rihal, Kan Liu, P Christian Schulze, Matteo Bianco, Lucas Jörg, Hans Rickli, Gonçalo Pestana, Thanh H Nguyen, Michael Böhm, Lars S Maier, Fausto J Pinto, Petr Widimský, Stephan B Felix, Grzegorz Opolski, Ruediger C Braun-Dullaeus, Wolfgang Rottbauer, Gerd Hasenfuß, Burkert M Pieske, Heribert Schunkert, Martin Borggrefe, Holger Thiele, Johann Bauersachs, Hugo A Katus, John D Horowitz, Carlo Di Mario, Thomas Münzel, Filippo Crea, Jeroen J Bax, Thomas F Lüscher, Frank Ruschitzka, Jelena R Ghadri, Christian Templin,

<h4>Aims</h4>Acute pulmonary disorders are known physical triggers of takotsubo syndrome (TTS). This study aimed to investigate prevalence of acute pulmonary triggers in patients with TTS and their impact on outcomes.<h4>Methods and results</h4>Patients with TTS were enrolled from the International Takotsubo Registry and screened for triggering factors and comorbidities. Patients were ... Read more >>

ESC Heart Fail (ESC heart failure)
[2021, :]

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Digitalization of presence events in the COVID-19 pandemia - the lecturers' perspective.

Marc Gottschalk, Katrin Werwick, Christian Albert, Soenke Weinert, Alexander Schmeißer, Philipp Stieger, Ruediger C Braun-Dullaeus,

<b>Objective:</b> Due to the COVID-19 pandemic a large part of attendance in medical education became impossible for reasons of disease control. Teachers had to switch to online courses at short notice. The associated developmental push of digital teaching methods, such as online teaching, has anticipated changes, some of which are ... Read more >>

GMS J Med Educ (GMS journal for medical education)
[2021, 38(1):Doc30]

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Pressure-volume loop validation of TAPSE/PASP for right ventricular arterial coupling in heart failure with pulmonary hypertension.

Alexander Schmeisser, Thomas Rauwolf, Thomas Groscheck, Siegfried Kropf, Blerim Luani, Ivan Tanev, Michael Hansen, Saskia Meißler, Paul Steendijk, Ruediger C Braun-Dullaeus,

<h4>Aims</h4>The aim of this study was to validate the tricuspid annular plane systolic excursion/systolic pulmonary artery (PA) pressure (TAPSE/PASP) ratio with the invasive pressure-volume (PV) loop-derived end-systolic right ventricular (RV) elastance/PA elastance (Ees/Ea) ratio in patients with heart failure with reduced ejection fraction (HFREF) and secondary pulmonary hypertension (PH).<h4>Methods and ... Read more >>

Eur Heart J Cardiovasc Imaging (European heart journal. Cardiovascular Imaging)
[2021, 22(2):168-176]

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Coexistence and outcome of coronary artery disease in Takotsubo syndrome.

L Christian Napp, Victoria L Cammann, Milosz Jaguszewski, Konrad A Szawan, Manfred Wischnewsky, Sebastiano Gili, Maike Knorr, Susanne Heiner, Rodolfo Citro, Eduardo Bossone, Fabrizio D'Ascenzo, Michael Neuhaus, Jennifer Franke, Ioana Sorici-Barb, Michel Noutsias, Christof Burgdorf, Wolfgang Koenig, Behrouz Kherad, Annahita Sarcon, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Mahir Karakas, Alexander Pott, Philippe Meyer, Jose D Arroja, Adrian Banning, Florim Cuculi, Richard Kobza, Thomas A Fischer, Tuija Vasankari, K E Juhani Airaksinen, Christian Hauck, Carla Paolini, Claudio Bilato, Yoichi Imori, Ken Kato, Yoshio Kobayashi, Grzegorz Opolski, Monika Budnik, Rafal Dworakowski, Philip MacCarthy, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Wolfgang Dichtl, Christina Chan, Paul Bridgman, Daniel Beug, Clément Delmas, Olivier Lairez, Ibrahim El-Battrawy, Ibrahim Akin, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, John D Horowitz, Karolina Polednikova, Petr Tousek, Petr Widimský, David E Winchester, Jan Galuszka, Christian Ukena, Gregor Poglajen, Pedro Carrilho-Ferreira, Carlo Di Mario, Abhiram Prasad, Charanjit S Rihal, P Christian Schulze, Matteo Bianco, Filippo Crea, Martin Borggrefe, Lars S Maier, Fausto J Pinto, Ruediger C Braun-Dullaeus, Wolfgang Rottbauer, Hugo A Katus, Gerd Hasenfuß, Carsten Tschöpe, Burkert M Pieske, Holger Thiele, Heribert Schunkert, Michael Böhm, Stephan B Felix, Thomas Münzel, Jeroen J Bax, Johann Bauersachs, Eugene Braunwald, Thomas F Lüscher, Frank Ruschitzka, Jelena R Ghadri, Christian Templin,

<h4>Aims</h4>Takotsubo syndrome (TTS) is an acute heart failure syndrome, which shares many features with acute coronary syndrome (ACS). Although TTS was initially described with angiographically normal coronary arteries, smaller studies recently indicated a potential coexistence of coronary artery disease (CAD) in TTS patients. This study aimed to determine the coexistence, ... Read more >>

Eur Heart J (European heart journal)
[2020, 41(34):3255-3268]

Cited: 3 times

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Age-Related Variations in Takotsubo Syndrome.

Victoria L Cammann, Konrad A Szawan, Barbara E Stähli, Ken Kato, Monika Budnik, Manfred Wischnewsky, Sara Dreiding, Rena A Levinson, Davide Di Vece, Sebastiano Gili, Rodolfo Citro, Eduardo Bossone, Michael Neuhaus, Jennifer Franke, Benjamin Meder, Miłosz Jaguszewski, Michel Noutsias, Maike Knorr, Susanne Heiner, Fabrizio D'Ascenzo, Wolfgang Dichtl, Christof Burgdorf, Behrouz Kherad, Carsten Tschöpe, Annahita Sarcon, Jerold Shinbane, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Mahir Karakas, Wolfgang Koenig, Alexander Pott, Philippe Meyer, Marco Roffi, Adrian Banning, Mathias Wolfrum, Florim Cuculi, Richard Kobza, Thomas A Fischer, Tuija Vasankari, K E Juhani Airaksinen, L Christian Napp, Rafal Dworakowski, Philip MacCarthy, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Christina Chan, Paul Bridgman, Daniel Beug, Clément Delmas, Olivier Lairez, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, Ibrahim El-Battrawy, Ibrahim Akin, Karolina Poledniková, Petr Toušek, David E Winchester, Jan Galuszka, Christian Ukena, Gregor Poglajen, Pedro Carrilho-Ferreira, Christian Hauck, Carla Paolini, Claudio Bilato, Yoshio Kobayashi, Toshihiro Shoji, Iwao Ishibashi, Masayuki Takahara, Toshiharu Himi, Jehangir Din, Ali Al-Shammari, Abhiram Prasad, Charanjit S Rihal, Kan Liu, P Christian Schulze, Matteo Bianco, Lucas Jörg, Hans Rickli, Gonçalo Pestana, Thanh H Nguyen, Michael Böhm, Lars S Maier, Fausto J Pinto, Petr Widimský, Stephan B Felix, Ruediger C Braun-Dullaeus, Wolfgang Rottbauer, Gerd Hasenfuß, Burkert M Pieske, Heribert Schunkert, Martin Borggrefe, Holger Thiele, Johann Bauersachs, Hugo A Katus, John D Horowitz, Carlo Di Mario, Thomas Münzel, Filippo Crea, Jeroen J Bax, Thomas F Lüscher, Frank Ruschitzka, Jelena R Ghadri, Grzegorz Opolski, Christian Templin,

<h4>Background</h4>Takotsubo syndrome (TTS) occurs predominantly in post-menopausal women but is also found in younger patients.<h4>Objectives</h4>This study aimed to investigate age-related differences in TTS.<h4>Methods</h4>Patients diagnosed with TTS and enrolled in the International Takotsubo Registry between January 2011 and February 2017 were included in this analysis and were stratified by age (younger: ≤50 ... Read more >>

J Am Coll Cardiol (Journal of the American College of Cardiology)
[2020, 75(16):1869-1877]

Cited: 2 times

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DNA-PK: gatekeeper for IKKγ/NEMO nucleocytoplasmic shuttling in genotoxic stress-induced NF-kappaB activation.

Senad Medunjanin, Maximilian Putzier, Till Nöthen, Sönke Weinert, Thilo Kähne, Blerim Luani, Werner Zuschratter, Ruediger C Braun-Dullaeus,

The transcription factors of the nuclear factor κB (NF-κB) family play a pivotal role in the cellular response to DNA damage. Genotoxic stress-induced activation of NF-κB differs from the classical canonical pathway by shuttling of the NF-κB Essential Modifier (IKKγ/NEMO) subunit through the nucleus. Here, we show that DNA-dependent protein ... Read more >>

Cell Mol Life Sci (Cellular and molecular life sciences : CMLS)
[2020, 77(20):4133-4142]

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Impact of aspirin on takotsubo syndrome: a propensity score-based analysis of the InterTAK Registry.

Fabrizio D'Ascenzo, Sebastiano Gili, Maurizio Bertaina, Mario Iannaccone, Victoria L Cammann, Davide Di Vece, Ken Kato, Andrea Saglietto, Konrad A Szawan, Antonio H Frangieh, Beatrice Boffini, Margherita Annaratone, Annahita Sarcon, Rena A Levinson, Jennifer Franke, L Christian Napp, Milosz Jaguszewski, Michel Noutsias, Thomas Münzel, Maike Knorr, Susanne Heiner, Hugo A Katus, Christof Burgdorf, Heribert Schunkert, Holger Thiele, Johann Bauersachs, Carsten Tschöpe, Burkert M Pieske, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Gerd Hasenfuß, Mahir Karakas, Wolfgang Koenig, Wolfgang Rottbauer, Samir M Said, Ruediger C Braun-Dullaeus, Adrian Banning, Florim Cuculi, Richard Kobza, Thomas A Fischer, Tuija Vasankari, K E Juhani Airaksinen, Grzegorz Opolski, Rafal Dworakowski, Philip MacCarthy, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Filippo Crea, Wolfgang Dichtl, Wolfgang M Franz, Klaus Empen, Stephan B Felix, Clément Delmas, Olivier Lairez, Ibrahim El-Battrawy, Ibrahim Akin, Martin Borggrefe, John D Horowitz, Martin Kozel, Petr Tousek, Petr Widimský, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, Giuseppe Biondi-Zoccai, David E Winchester, Christian Ukena, Michael Neuhaus, Jeroen J Bax, Abhiram Prasad, Carlo Di Mario, Michael Böhm, Mauro Gasparini, Frank Ruschitzka, Eduardo Bossone, Rodolfo Citro, Mauro Rinaldi, Gaetano Maria De Ferrari, Thomas Lüscher, Jelena R Ghadri, Christian Templin,

<h4>Aims</h4>The aim of the present study was to investigate the impact of aspirin on prognosis in takotsubo syndrome (TTS).<h4>Methods and results</h4>Patients from the International Takotsubo (InterTAK) Registry were categorized into two groups based on aspirin prescription at discharge. A comparison of clinical outcomes between groups was performed using an adjusted ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2020, 22(2):330-337]

Cited: 2 times

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Intraventricular Thrombus Formation and Embolism in Takotsubo Syndrome: Insights From the International Takotsubo Registry.

Katharina J Ding, Victoria L Cammann, Konrad A Szawan, Barbara E Stähli, Manfred Wischnewsky, Davide Di Vece, Rodolfo Citro, Milosz Jaguszewski, Burkhardt Seifert, Annahita Sarcon, Maike Knorr, Susanne Heiner, Sebastiano Gili, Fabrizio D'Ascenzo, Michael Neuhaus, L Christian Napp, Jennifer Franke, Michel Noutsias, Christof Burgdorf, Wolfgang Koenig, Behrouz Kherad, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Mahir Karakas, Alexander Pott, Philippe Meyer, Jose D Arroja, Adrian Banning, Florim Cuculi, Richard Kobza, Thomas A Fischer, Tuija Vasankari, K E Juhani Airaksinen, Carla Paolini, Claudio Bilato, Pedro Carrilho-Ferreira, Grzegorz Opolski, Rafal Dworakowski, Philip MacCarthy, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Wolfgang Dichtl, Christina Chan, Paul Bridgman, Clément Delmas, Olivier Lairez, Ibrahim El-Battrawy, Ibrahim Akin, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, Martin Kozel, Petr Tousek, Petr Widimský, David E Winchester, Jan Galuszka, Christian Ukena, John D Horowitz, Carlo Di Mario, Abhiram Prasad, Charanjit S Rihal, Fausto J Pinto, Filippo Crea, Martin Borggrefe, Ruediger C Braun-Dullaeus, Wolfgang Rottbauer, Johann Bauersachs, Hugo A Katus, Gerd Hasenfuß, Carsten Tschöpe, Burkert M Pieske, Holger Thiele, Heribert Schunkert, Michael Böhm, Stephan B Felix, Thomas Münzel, Jeroen J Bax, Thomas F Lüscher, Frank Ruschitzka, Jelena R Ghadri, Eduardo Bossone, Christian Templin,

OBJECTIVE:Takotsubo syndrome (TTS) is characterized by acute left ventricular dysfunction, which can contribute to intraventricular thrombus and embolism. Still, prevalence and clinical impact of thrombus formation and embolic events on outcome of TTS patients remain unclear. This study aimed to investigate clinical features and outcomes of patients with and without ... Read more >>

Arterioscler Thromb Vasc Biol (Arteriosclerosis, thrombosis, and vascular biology)
[2020, 40(1):279-287]

Cited: 2 times

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Clinical Predictors and Prognostic Impact of Recovery of Wall Motion Abnormalities in Takotsubo Syndrome: Results From the International Takotsubo Registry.

Stjepan Jurisic, Sebastiano Gili, Victoria L Cammann, Ken Kato, Konrad A Szawan, Fabrizio D'Ascenzo, Milosz Jaguszewski, Eduardo Bossone, Rodolfo Citro, Annahita Sarcon, L Christian Napp, Jennifer Franke, Michel Noutsias, Maike Knorr, Susanne Heiner, Christof Burgdorf, Wolfgang Koenig, Alexander Pott, Behrouz Kherad, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Mahir Karakas, Philippe Meyer, Jose David Arroja, Adrian Banning, Florim Cuculi, Richard Kobza, Thomas A Fischer, Tuija Vasankari, K E Juhani Airaksinen, Rafal Dworakowski, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Wolfgang Dichtl, Christina Chan, Paul Bridgman, Daniel Beug, Clément Delmas, Olivier Lairez, Martin Kozel, Petr Tousek, David E Winchester, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, Ibrahim El-Battrawy, Ibrahim Akin, Jan Galuszka, Christian Ukena, Gregor Poglajen, Carla Paolini, Claudio Bilato, Pedro Carrilho-Ferreira, Fausto J Pinto, Grzegorz Opolski, Philip MacCarthy, Yoshio Kobayashi, Abhiram Prasad, Charanjit S Rihal, Petr Widimský, John D Horowitz, Carlo Di Mario, Filippo Crea, Carsten Tschöpe, Burkert M Pieske, Gerd Hasenfuß, Wolfgang Rottbauer, Ruediger C Braun-Dullaeus, Stephan B Felix, Martin Borggrefe, Holger Thiele, Johann Bauersachs, Hugo A Katus, Heribert Schunkert, Thomas Münzel, Michael Böhm, Jeroen J Bax, Thomas F Lüscher, Frank Ruschitzka, Jelena R Ghadri, Christian Templin,

Background Left ventricular (LV) recovery in takotsubo syndrome (TTS) occurs over a wide-ranging interval, varying from hours to weeks. We sought to investigate the clinical predictors and prognostic impact of recovery time for TTS patients. Methods and Results TTS patients from the International Takotsubo Registry were included in this study. ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2019, 8(21):e011194]

Cited: 2 times

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Prediction of short- and long-term mortality in takotsubo syndrome: the InterTAK Prognostic Score.

Manfred B Wischnewsky, Alessandro Candreva, Beatrice Bacchi, Victoria L Cammann, Ken Kato, Konrad A Szawan, Sebastiano Gili, Fabrizio D'Ascenzo, Wolfgang Dichtl, Rodolfo Citro, Eduardo Bossone, Michael Neuhaus, Jennifer Franke, Ioana Sorici-Barb, Milosz Jaguszewski, Michel Noutsias, Maike Knorr, Susanne Heiner, Christof Burgdorf, Behrouz Kherad, Carsten Tschöpe, Annahita Sarcon, Jerold Shinbane, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Mahir Karakas, Wolfgang Koenig, Alexander Pott, Philippe Meyer, Jose David Arroja, Adrian Banning, Florim Cuculi, Richard Kobza, Thomas A Fischer, Tuija Vasankari, K E Juhani Airaksinen, L Christian Napp, Monika Budnik, Rafal Dworakowski, Philip MacCarthy, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Christina Chan, Paul Bridgman, Daniel Beug, Clément Delmas, Olivier Lairez, Ibrahim El-Battrawy, Ibrahim Akin, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, Martin Kozel, Petr Tousek, David E Winchester, Jan Galuszka, Christian Ukena, Gregor Poglajen, Pedro Carrilho-Ferreira, Christian Hauck, Carla Paolini, Claudio Bilato, Abhiram Prasad, Charanjit S Rihal, Kan Liu, P Christian Schulze, Matteo Bianco, Lucas Jörg, Hans Rickli, Thanh H Nguyen, Yoshio Kobayashi, Michael Böhm, Lars S Maier, Fausto J Pinto, Petr Widimský, Martin Borggrefe, Stephan B Felix, Grzegorz Opolski, Ruediger C Braun-Dullaeus, Wolfgang Rottbauer, Gerd Hasenfuß, Burkert M Pieske, Heribert Schunkert, Holger Thiele, Johann Bauersachs, Hugo A Katus, John Horowitz, Carlo Di Mario, Thomas Münzel, Filippo Crea, Jeroen J Bax, Thomas F Lüscher, Frank Ruschitzka, Jelena R Ghadri, Christian Templin,

Eur J Heart Fail (European journal of heart failure)
[2019, 21(11):1469-1472]

Cited: 2 times

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Clinical Features and Outcomes of Patients With Malignancy and Takotsubo Syndrome: Observations From the International Takotsubo Registry.

Victoria L Cammann, Annahita Sarcon, Katharina J Ding, Burkhardt Seifert, Ken Kato, Davide Di Vece, Konrad A Szawan, Sebastiano Gili, Stjepan Jurisic, Beatrice Bacchi, Jozef Micek, Antonio H Frangieh, L Christian Napp, Milosz Jaguszewski, Eduardo Bossone, Rodolfo Citro, Fabrizio D'Ascenzo, Jennifer Franke, Michel Noutsias, Maike Knorr, Susanne Heiner, Christof Burgdorf, Wolfgang Koenig, Holger Thiele, Carsten Tschöpe, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Mahir Karakas, Adrian Banning, Florim Cuculi, Richard Kobza, Thomas A Fischer, Tuija Vasankari, K E Juhani Airaksinen, Rafal Dworakowski, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Wolfgang Dichtl, Clément Delmas, Olivier Lairez, John D Horowitz, Martin Kozel, Petr Widimský, Petr Tousek, David E Winchester, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, Ibrahim El-Battrawy, Ibrahim Akin, Christian Ukena, Johann Bauersachs, Burkert M Pieske, Gerd Hasenfuß, Wolfgang Rottbauer, Ruediger C Braun-Dullaeus, Grzegorz Opolski, Philip MacCarthy, Stephan B Felix, Martin Borggrefe, Carlo Di Mario, Filippo Crea, Hugo A Katus, Heribert Schunkert, Thomas Münzel, Michael Böhm, Jeroen J Bax, Abhiram Prasad, Jerold Shinbane, Thomas F Lüscher, Frank Ruschitzka, Jelena R Ghadri, Christian Templin,

Background Clinical characteristics and outcomes of takotsubo syndrome (TTS) patients with malignancy have not been fully elucidated. This study sought to explore differences in clinical characteristics and to investigate short- and long-term outcomes in TTS patients with or without malignancy. Methods and Results TTS patients were enrolled from the International ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2019, 8(15):e010881]

Cited: 9 times

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Cardiac arrest in takotsubo syndrome: results from the InterTAK Registry.

Sebastiano Gili, Victoria L Cammann, Susanne A Schlossbauer, Ken Kato, Fabrizio D'Ascenzo, Davide Di Vece, Stjepan Jurisic, Jozef Micek, Slayman Obeid, Beatrice Bacchi, Konrad A Szawan, Flurina Famos, Annahita Sarcon, Rena Levinson, Katharina J Ding, Burkhardt Seifert, Olivia Lenoir, Eduardo Bossone, Rodolfo Citro, Jennifer Franke, L Christian Napp, Milosz Jaguszewski, Michel Noutsias, Thomas Münzel, Maike Knorr, Susanne Heiner, Hugo A Katus, Christof Burgdorf, Heribert Schunkert, Holger Thiele, Johann Bauersachs, Carsten Tschöpe, Burkert M Pieske, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Gerd Hasenfuß, Mahir Karakas, Wolfgang Koenig, Wolfgang Rottbauer, Samir M Said, Ruediger C Braun-Dullaeus, Adrian Banning, Florim Cuculi, Richard Kobza, Thomas A Fischer, Tuija Vasankari, K E Juhani Airaksinen, Grzegorz Opolski, Rafal Dworakowski, Philip MacCarthy, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Filippo Crea, Wolfgang Dichtl, Klaus Empen, Stephan B Felix, Clément Delmas, Olivier Lairez, Ibrahim El-Battrawy, Ibrahim Akin, Martin Borggrefe, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, John D Horowitz, Martin Kozel, Petr Tousek, Petr Widimský, David E Winchester, Christian Ukena, Fiorenzo Gaita, Carlo Di Mario, Manfred B Wischnewsky, Jeroen J Bax, Abhiram Prasad, Michael Böhm, Frank Ruschitzka, Thomas F Lüscher, Jelena R Ghadri, Christian Templin,

<h4>Aims</h4>We aimed to evaluate the frequency, clinical features, and prognostic implications of cardiac arrest (CA) in takotsubo syndrome (TTS).<h4>Methods and results</h4>We reviewed the records of patients with CA and known heart rhythm from the International Takotsubo Registry. The main outcomes were 60-day and 5-year mortality. In addition, predictors of mortality ... Read more >>

Eur Heart J (European heart journal)
[2019, 40(26):2142-2151]

Cited: 3 times

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Effects of ATP administration on isolated swine hearts: Implications for ex vivo perfusion and cardiac transplantation.

Maria S Seewald, Erik N Gaasedelen, Tinen L Iles, Lars M Mattison, Alexander R Mattson, Megan M Schmidt, Ruediger C Braun-Dullaeus, Paul A Iaizzo,

Exp Biol Med (Maywood) (Experimental biology and medicine (Maywood, N.J.))
[2019, 244(11):915-922]

Cited: 0 times

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Outcomes Associated With Cardiogenic Shock in Takotsubo Syndrome.

Davide Di Vece, Rodolfo Citro, Victoria L Cammann, Ken Kato, Sebastiano Gili, Konrad A Szawan, Jozef Micek, Stjepan Jurisic, Katharina J Ding, Beatrice Bacchi, Moritz Schwyzer, Alessandro Candreva, Eduardo Bossone, Fabrizio D'Ascenzo, Annahita Sarcon, Jennifer Franke, L Christian Napp, Milosz Jaguszewski, Michel Noutsias, Thomas Münzel, Maike Knorr, Susanne Heiner, Hugo A Katus, Christof Burgdorf, Heribert Schunkert, Holger Thiele, Johann Bauersachs, Carsten Tschöpe, Burkert M Pieske, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Gerd Hasenfuβ, Mahir Karakas, Wolfgang Koenig, Wolfgang Rottbauer, Samir M Said, Ruediger C Braun-Dullaeus, Adrian Banning, Florim Cuculi, Richard Kobza, Thomas A Fischer, Tuija Vasankari, K E Juhani Airaksinen, Grzegorz Opolski, Rafal Dworakowski, Philip MacCarthy, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Filippo Crea, Wolfgang Dichtl, Klaus Empen, Stephan B Felix, Clément Delmas, Olivier Lairez, Ibrahim El-Battrawy, Ibrahim Akin, Martin Borggrefe, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, John Horowitz, Martin Kozel, Petr Tousek, Petr Widimský, David E Winchester, Christian Ukena, Carlo Di Mario, Abhiram Prasad, Michael Böhm, Jeroen J Bax, Thomas F Lüscher, Frank Ruschitzka, Jelena R Ghadri, Christian Templin,

Circulation (Circulation)
[2019, 139(3):413-415]

Cited: 10 times

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Long-Term Prognosis of Patients With Takotsubo Syndrome.

Jelena R Ghadri, Ken Kato, Victoria L Cammann, Sebastiano Gili, Stjepan Jurisic, Davide Di Vece, Alessandro Candreva, Katharina J Ding, Jozef Micek, Konrad A Szawan, Beatrice Bacchi, Rahel Bianchi, Rena A Levinson, Manfred Wischnewsky, Burkhardt Seifert, Susanne A Schlossbauer, Rodolfo Citro, Eduardo Bossone, Thomas Münzel, Maike Knorr, Susanne Heiner, Fabrizio D'Ascenzo, Jennifer Franke, Annahita Sarcon, L Christian Napp, Milosz Jaguszewski, Michel Noutsias, Hugo A Katus, Christof Burgdorf, Heribert Schunkert, Holger Thiele, Johann Bauersachs, Carsten Tschöpe, Burkert M Pieske, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Gerd Hasenfuß, Mahir Karakas, Wolfgang Koenig, Wolfgang Rottbauer, Samir M Said, Ruediger C Braun-Dullaeus, Adrian Banning, Florim Cuculi, Richard Kobza, Thomas A Fischer, Tuija Vasankari, K E Juhani Airaksinen, Grzegorz Opolski, Rafal Dworakowski, Philip MacCarthy, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Filippo Crea, Wolfgang Dichtl, Klaus Empen, Stephan B Felix, Clément Delmas, Olivier Lairez, Ibrahim El-Battrawy, Ibrahim Akin, Martin Borggrefe, John Horowitz, Martin Kozel, Petr Tousek, Petr Widimský, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, David E Winchester, Christian Ukena, Jeroen J Bax, Abhiram Prasad, Michael Böhm, Thomas F Lüscher, Frank Ruschitzka, Christian Templin,

BACKGROUND:Prognosis of Takotsubo syndrome (TTS) remains controversial due to scarcity of available data. Additionally, the effect of the triggering factors remains elusive. OBJECTIVES:This study compared prognosis between TTS and acute coronary syndrome (ACS) patients and investigated short- and long-term outcomes in TTS based on different triggers. METHODS:Patients with TTS were ... Read more >>

J Am Coll Cardiol (Journal of the American College of Cardiology)
[2018, 72(8):874-882]

Cited: 41 times

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Impact of internal and external electrical cardioversion on cardiac specific enzymes and inflammation in patients with atrial fibrillation and heart failure.

Philipp Stieger, Obaida R Rana, Erol Saygili, Haschmatulla Zazai, Thomas Rauwolf, Conrad Genz, Rajen Bali, Ruediger C Braun-Dullaeus, Samir M Said,

BACKGROUND:Implantable cardioverter/defibrillator (ICD) shocks can cause myocardial injury, contributing to the progression of the underlying heart disease. The aim was to evaluate whether internal electrical cardioversion (int-CV) via the ICD or conventional external CV (ext-CV) of persistent atrial fibrillation (AF) in heart failure (HF) patients induces myocardial injury and initiates ... Read more >>

J Cardiol (Journal of cardiology)
[2018, 72(2):135-139]

Cited: 1 time

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Right heart function interacts with left ventricular remodeling after CRT: A pressure volume loop study.

Alexander Schmeisser, Thomas Rauwolf, Ali Ghanem, Thomas Groscheck, Daniela Adolf, Frank Grothues, Katharina Fischbach, Ortrud Kosiek, Christof Huth, Siegfried Kropf, Stefan Lange, Blerim Luani, Jan Smid, Marc Henning Schäfer, Jens Schreiber, Ivan Tanev, Fabian Wengler, Naira Beniki Yeritsyan, Paul Steendijk, Ruediger C Braun-Dullaeus,

BACKGROUND:Right ventricular (RV) dysfunction is recognized as a cardinal prognostic marker in systolic heart failure patients. Conflicting data exist on the interaction of RV function and left ventricular (LV) reverse remodeling after cardiac resynchronization therapy (CRT). This prospective monocentric trial was set up to assess the predictive value of baseline ... Read more >>

Int J Cardiol (International journal of cardiology)
[2018, 268:156-161]

Cited: 4 times

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Intravital Microscopy of Monocyte Homing and Tumor-Related Angiogenesis in a Murine Model of Peripheral Arterial Disease.

Martin Wagner, Claudia Baer, Werner Zuschratter, Monika Riek-Burchardt, Christian Deffge, Soenke Weinert, Jerry C Lee, Ruediger C Braun-Dullaeus, Joerg Herold,

The therapeutic goal for peripheral arterial disease and ischemic heart disease is to increase blood flow to ischemic areas caused by hemodynamic stenosis. Vascular surgery is a viable option in selected cases, but for patients without indications for surgery such as progression to rest pain, critical limb ischemia, or major ... Read more >>

J Vis Exp (Journal of visualized experiments : JoVE)
[2017, (126):]

Cited: 1 time

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Cytoprotective activated protein C averts Nlrp3 inflammasome-induced ischemia-reperfusion injury via mTORC1 inhibition.

Sumra Nazir, Ihsan Gadi, Moh'd Mohanad Al-Dabet, Ahmed Elwakiel, Shrey Kohli, Sanchita Ghosh, Jayakumar Manoharan, Satish Ranjan, Fabian Bock, Ruediger C Braun-Dullaeus, Charles T Esmon, Tobias B Huber, Eric Camerer, Chris Dockendorff, John H Griffin, Berend Isermann, Khurrum Shahzad,

Cytoprotection by activated protein C (aPC) after ischemia-reperfusion injury (IRI) is associated with apoptosis inhibition. However, IRI is hallmarked by inflammation, and hence, cell-death forms disjunct from immunologically silent apoptosis are, in theory, more likely to be relevant. Because pyroptosis (ie, cell death resulting from inflammasome activation) is typically observed ... Read more >>

Blood (Blood)
[2017, 130(24):2664-2677]

Cited: 35 times

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Twenty-four-hour ambulatory blood pressure monitoring in very elderly patients: Comparison of in-hospital versus home follow-up results.

Claudia Cappelleri, Alin Janoschka, Reto Berli, Sibylle Kohler, Ruediger C Braun-Dullaeus, Ludwig T Heuss, Mathias Wolfrum,

Elevated blood pressure (BP) is frequently diagnosed in very elderly hospitalized patients. Accurate diagnosis of hypertension is challenging in the hospital environment, due to the "white coat effect," and both overtreatment and undertreatment can adversely affect clinical outcome. Twenty-four-hour ambulatory blood pressure monitoring (ABPM) has the potential to avoid the ... Read more >>

Medicine (Madr) (Medicine)
[2017, 96(34):e7692]

Cited: 6 times

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Factor VII activating protease (FSAP) influences vascular remodeling in the mouse hind limb ischemia model.

Joerg Herold, Steven Nowak, Sawa Kostin, Jan-Marcus Daniel, Alexander Francke, Saravanan Subramaniam, Ruediger C Braun-Dullaeus, Sandip M Kanse,

<h4>Background</h4>Investigations in factor VII activating protease (FSAP)<sup>-/-</sup> mice suggest a role for FSAP in stroke, thrombosis and neointima formation. Here, we analyzed the role of FSAP in vascular remodeling processes related to arteriogenesis and angiogenesis in the mouse hind limb ischemia model.<h4>Methods and results</h4>Femoral artery ligation was performed in mice ... Read more >>

Am J Transl Res (American journal of translational research)
[2017, 9(6):3084-3095]

Cited: 5 times

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GSK-3β controls NF-kappaB activity via IKKγ/NEMO.

Senad Medunjanin, Lisa Schleithoff, Christian Fiegehenn, Soenke Weinert, Werner Zuschratter, Ruediger C Braun-Dullaeus,

The NF-κB signaling pathway is central for the innate immune response and its deregulation is found in multiple disorders such as autoimmune, chronic inflammatory and metabolic diseases. IKKγ/NEMO is essential for NF-κB activation and NEMO dysfunction in humans has been linked to so-called progeria syndromes, which are characterized by advanced ... Read more >>

Sci Rep (Scientific reports)
[2016, 6:38553]

Cited: 14 times

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A novel clinical score (InterTAK Diagnostic Score) to differentiate takotsubo syndrome from acute coronary syndrome: results from the International Takotsubo Registry.

Jelena R Ghadri, Victoria L Cammann, Stjepan Jurisic, Burkhardt Seifert, L Christian Napp, Johanna Diekmann, Dana Roxana Bataiosu, Fabrizio D'Ascenzo, Katharina J Ding, Annahita Sarcon, Elycia Kazemian, Tanja Birri, Frank Ruschitzka, Thomas F Lüscher, Christian Templin, ,

<h4>Aims</h4>Clinical presentation of takotsubo syndrome (TTS) mimics acute coronary syndrome (ACS) and does not allow differentiation. We aimed to develop a clinical score to estimate the probability of TTS and to distinguish TTS from ACS in the acute stage.<h4>Methods and results</h4>Patients with TTS were recruited from the International Takotsubo Registry ... Read more >>

Eur J Heart Fail (European journal of heart failure)
[2017, 19(8):1036-1042]

Cited: 27 times

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