Full Text Journal Articles by
Author Rosalind J Wright

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Influences of climate change on childhood asthma and allergy risk.

Rosalind J Wright,

Lancet Child Adolesc Health (The Lancet. Child & adolescent health)
[2020, 4(12):859-860]

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Associations of Maternal Trait Anger Expression and Lifetime Traumatic and Non-traumatic Experiences with Preterm Birth.

Whitney Cowell, Lilly Taing, Talia Askowitz, Michelle Bosquet Enlow, Michele R Hacker, Rosalind J Wright,

<b>Objectives:</b>Most studies examining psychosocial factors contributing to preterm birth (PTB) have focused on negative life events. Studies examining the influence of negative emotion, in particular maternal anger, remain sparse. We examined associations of maternal trait anger expression and lifetime traumatic and non-traumatic experiences with the risk of PTB.<br><br><b>Methods:</b>Mother-newborn pairs were ... Read more >>

Matern Child Health J (Maternal and child health journal)
[2020, :]

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Disentangling Associations Among Maternal Lifetime and Prenatal Stress, Psychological Functioning During Pregnancy, Maternal Race/Ethnicity, and Infant Negative Affectivity at Age 6 Months: A Mixtures Approach.

Rebecca K Campbell, Paul Curtin, Michelle Bosquet Enlow, Kelly J Brunst, Robert O Wright, Rosalind J Wright,

<b>Purpose:</b> Maternal stress and psychological dysfunction in pregnancy are independently linked with fetal neurodevelopment. Stress encompasses environmental stressors and psychological and physiological responses. Stressors and psychopathology co-occur with patterns differing by race/ethnicity. We aimed to extend environmental mixtures methodology to elucidate prenatal stress associations with infant negative affectivity (NA) in ... Read more >>

Health Equity (Health equity)
[2020, 4(1):489-499]

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Cardiac sympathetic activation and parasympathetic withdrawal during psychosocial stress exposure in 6-month-old infants.

Thomas Ritz, Stefan M Schulz, David Rosenfield, Rosalind J Wright, Michelle Bosquet Enlow,

Infant autonomic reactivity to stress is a potential predictor of later life health complications, but research has not sufficiently examined sympathetic activity, controlled for effects of physical activity and respiration, or studied associations among autonomic adjustments, cardiac activity, and affect in infants. We studied 278 infants during the repeated Still-Face ... Read more >>

Psychophysiology (Psychophysiology)
[2020, :e13673]

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Associations Between Maternal Lifetime Stress and Placental Mitochondrial DNA Mutations in an Urban Multiethnic Cohort.

Kelly J Brunst, Li Zhang, Xiang Zhang, Andrea A Baccarelli, Tessa Bloomquist, Rosalind J Wright,

BACKGROUND:Disrupted placental functioning due to stress can have lifelong implications. Cumulative stress and trauma are likely to have lasting impacts on maternal physiological functioning and offspring development, resulting in increased risk for later-life complex disorders for which racial disparities exist. METHODS:This study examined the association between maternal lifetime stress and ... Read more >>

Biol Psychiatry (Biological psychiatry)
[2020, :]

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The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations.

Anastasia Ivanova, Elliot Israel, Lisa M LaVange, Michael C Peters, Loren C Denlinger, Wendy C Moore, Leonard B Bacharier, M Alison Marquis, Nathan M Gotman, Michael R Kosorok, Chalmer Tomlinson, David T Mauger, Steve N Georas, Rosalind J Wright, Patricia Noel, Gary L Rosner, Praveen Akuthota, Dean Billheimer, Eugene R Bleecker, Juan Carlos Cardet, Mario Castro, Emily A DiMango, Serpil C Erzurum, John V Fahy, Merritt L Fajt, Benjamin M Gaston, Fernando Holguin, Sonia Jain, Nicholas J Kenyon, Jerry A Krishnan, Monica Kraft, Rajesh Kumar, Mark C Liu, Ngoc P Ly, James N Moy, Wanda Phipatanakul, Kristie Ross, Lewis J Smith, Stanley J Szefler, W Gerald Teague, Michael E Wechsler, Sally E Wenzel, Steven R White,

The Precision Interventions for Severe and/or Exacerbation-prone Asthma (PrecISE) study is an adaptive platform trial designed to investigate novel interventions to severe asthma. The study is conducted under a master protocol and utilizes a crossover design with each participant receiving up to five interventions and at least one placebo. Treatment ... Read more >>

J Biopharm Stat (Journal of biopharmaceutical statistics)
[2020, :1-12]

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Associations between maternal lifetime stressors and negative events in pregnancy and breast milk-derived extracellular vesicle microRNAs in the programming of intergenerational stress mechanisms (PRISM) pregnancy cohort.

Anne K Bozack, Elena Colicino, Rodosthenis Rodosthenous, Tessa R Bloomquist, Andrea A Baccarelli, Robert O Wright, Rosalind J Wright, Alison G Lee,

Maternal stress is associated with adverse child health. Breast milk microRNAs encapsulated in extracellular vesicles (EVs) are involved in mother-infant biochemical communication during early-life programming. We leverage the PRogramming of Intergenerational Stress Mechanisms (PRISM) pregnancy cohort to investigate associations between maternal stress and breast milk EV-microRNAs. Lifetime stress and negative life events ... Read more >>

Epigenetics (Epigenetics)
[2020, :1-16]

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Prenatal toxic metal mixture exposure and newborn telomere length: Modification by maternal antioxidant intake.

Whitney Cowell, Elena Colicino, Eva Tanner, Chitra Amarasiriwardena, Syam S Andra, Valentina Bollati, Srimathi Kannan, Harish Ganguri, Chris Gennings, Robert O Wright, Rosalind J Wright,

BACKGROUND:Telomere length (TL) predicts the onset of cellular senescence and correlates with longevity and age-related disease risk. While telomeres erode throughout life, adults display fixed ranking and tracking of TL, supporting the importance of the early environment in determining inter-individual variability across the life course. Given their guanine-rich structure, telomeres ... Read more >>

Environ Res (Environmental research)
[2020, 190:110009]

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Integrated and diurnal indices of maternal pregnancy cortisol in relation to sex-specific parasympathetic responsivity to stress in infants.

Whitney Cowell, Jennifer E Khoury, Carter R Petty, Helen E Day, Brian E Benítez, Molly K Cunningham, Stefan M Schulz, Thomas Ritz, Rosalind J Wright, Michelle Bosquet Enlow,

Maternal hypothalamic-pituitary-adrenal axis activity may prenatally program sex-specific stress-response pathways. We investigated associations between maternal cortisol during pregnancy and infant parasympathetic responsivity to stress among 204 mother-infant pairs. Cortisol indices included 3rd trimester hair cortisol, as well as diurnal slope and area under the curve, derived from saliva samples collected ... Read more >>

Dev Psychobiol (Developmental psychobiology)
[2020, :]

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Maternal stress in relation to sex-specific expression of placental genes involved in nutrient transport, oxygen tension, immune response, and the glucocorticoid barrier.

Whitney Cowell, Maya Deyssenroth, Jia Chen, Rosalind J Wright,

INTRODUCTION:Murine models provide evidence that maternal stress during pregnancy can influence placenta morphology and function, including altered expression of genes involved in the maintenance and progression of pregnancy and fetal development. Corresponding research evaluating the impact of maternal stress on placental gene expression in humans is limited. We examined maternal ... Read more >>

Placenta (Placenta)
[2020, 96:19-26]

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Reopening Schools Safely: The Case for Collaboration, Constructive Disruption of Pre-Coronavirus 2019 Expectations, and Creative Solutions.

Dan M Cooper, Lisa Guay-Woodford, Bruce R Blazar, Scott Bowman, Carrie L Byington, Jeffrey Dome, Donald Forthal, Michael W Konstan, Nathan Kuppermann, Robert I Liem, Eduardo R Ochoa, Brad H Pollock, Olga Acosta Price, Bonnie W Ramsey, Lainie Friedman Ross, Ronald J Sokol, Rosalind J Wright,

J Pediatr (The Journal of pediatrics)
[2020, 223:183-185]

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Maternal Prenatal Psychosocial Stress and Prepregnancy BMI Associations with Fetal Iron Status.

Rebecca K Campbell, Marcela Tamayo-Ortiz, Alejandra Cantoral, Lourdes Schnaas, Erika Osorio-Valencia, Rosalind J Wright, Martha M Téllez-Rojo, Robert O Wright,

Background:Iron accrued in utero is critical for fetal and infant neurocognitive development. Psychosocial stress and obesity can each suppress fetal iron accrual. Their combined effects and differences by fetal sex are not known. In an observational pregnancy cohort study in Mexico City, we investigated associations of maternal prenatal life stressors, ... Read more >>

Curr Dev Nutr (Current developments in nutrition)
[2020, 4(2):nzaa018]

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Fluoride exposure and sleep patterns among older adolescents in the United States: a cross-sectional study of NHANES 2015-2016.

Ashley J Malin, Sonali Bose, Stefanie A Busgang, Chris Gennings, Michael Thorpy, Robert O Wright, Rosalind J Wright, Manish Arora,

BACKGROUND:Fluoride from environmental sources accumulates preferentially in the pineal gland which produces melatonin, the hormone that regulates the sleep-wake cycle. However, the effects of fluoride on sleep regulation remain unknown. This population-based study examined whether chronic low-level fluoride exposure is associated with sleep patterns and daytime sleepiness among older adolescents ... Read more >>

Environ Health (Environmental health : a global access science source)
[2019, 18(1):106]

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Prenatal polyunsaturated fatty acids and child asthma: Effect modification by maternal asthma and child sex.

Maria José Rosa, Terryl J Hartman, Margaret Adgent, Kourtney Gardner, Tebeb Gebretsadik, Paul E Moore, Robert L Davis, Kaja Z LeWinn, Nicole R Bush, Frances Tylavsky, Rosalind J Wright, Kecia N Carroll,

BACKGROUND:Findings on prenatal polyunsaturated fatty acid (PUFA) intake and child wheeze and asthma have been inconsistent. OBJECTIVE:We sought to examine associations between prenatal PUFA status and child wheeze/asthma and modifying effects of maternal asthma/atopy, child sex, and maternal race. METHODS:Analyses included 1019 mother-child dyads with omega-3 (n-3) and omega-3 (n-6) ... Read more >>

J Allergy Clin Immunol (The Journal of allergy and clinical immunology)
[2020, 145(3):800-807.e4]

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Blood manganese levels during pregnancy and postpartum depression: A cohort study among women in Mexico.

Nia McRae, Ghalib Bello, Katherine Svensson, Maritsa Solano-González, Rosalind J Wright, Megan M Niedzwiecki, Mariana Torres Calapiz, Chitra Amarasiriwardena, Lourdes Schnaas, Marcela Tamayo-Ortiz, Martha M Téllez-Rojo, Robert O Wright,

BACKGROUND:Occupational studies have shown an association between elevated Mn exposure and depressive symptoms. Blood Mn (BMn) naturally rises during pregnancy due to mobilization from tissues, suggesting it could contribute to pregnancy and postpartum depressive symptoms. OBJECTIVES:To assess the association between BMn levels during pregnancy and postpartum depression (PPD), creating opportunities ... Read more >>

Neurotoxicology (Neurotoxicology)
[2020, 76:183-190]

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Prenatal maternal stress and birth outcomes in rural Ghana: sex-specific associations.

Kenneth Ayuurebobi Ae-Ngibise, Blair J Wylie, Ellen Boamah-Kaali, Darby W Jack, Felix Boakye Oppong, Steven N Chillrud, Stephaney Gyaase, Seyram Kaali, Oscar Agyei, Patrick L Kinney, Mohammed Mujtaba, Rosalind J Wright, Kwaku Poku Asante, Alison G Lee,

BACKGROUND:In developed countries, prenatal maternal stress has been associated with poor fetal growth, however this has not been evaluated in rural sub-Saharan Africa. We evaluated the effect of prenatal maternal stress on fetal growth and birth outcomes in rural Ghana. METHODS:Leveraging a prospective, rural Ghanaian birth cohort, we ascertained prenatal ... Read more >>

BMC Pregnancy Childbirth (BMC pregnancy and childbirth)
[2019, 19(1):391]

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Data-driven discovery of mid-pregnancy immune markers associated with maternal lifetime stress: results from an urban pre-birth cohort.

Whitney Cowell, Elena Colicino, Alison G Lee, Michelle Bosquet Enlow, Julie D Flom, Cecilia Berin, Robert O Wright, Rosalind J Wright,

Changes to the maternal inflammatory milieu may be a mechanism through which maternal psychosocial stress is transmitted to the fetus. Research investigating a limited number of immune markers may miss important signals. We take a proteomics approach to investigate maternal lifetime stress and 92 biomarkers of immune system status. Participants ... Read more >>

Stress (Stress (Amsterdam, Netherlands))
[2020, 23(3):349-358]

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Prenatal Omega-3 and Omega-6 Polyunsaturated Fatty Acids and Childhood Atopic Dermatitis.

Kourtney G Gardner, Tebeb Gebretsadik, Terryl J Hartman, Maria J Rosa, Frances A Tylavsky, Margaret A Adgent, Paul E Moore, Mehmet Kocak, Nicole R Bush, Robert L Davis, Kaja Z Lewinn, Rosalind J Wright, Kecia N Carroll,

BACKGROUND:Atopic dermatitis is a common childhood disease, potentially influenced by prenatal nutritional exposures such as polyunsaturated fatty acids (PUFAs). OBJECTIVE:In a racially diverse cohort, we hypothesized that childhood atopic dermatitis would be associated with higher prenatal omega-6 (n-6) and lower omega-3 (n-3) PUFAs. METHODS:We included mother-child dyads, births 2006 to ... Read more >>

J Allergy Clin Immunol Pract (The journal of allergy and clinical immunology. In practice)
[2020, 8(3):937-944]

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Parental asthma occurrence, exacerbations and risk of attention-deficit/hyperactivity disorder.

Xiaoqin Liu, Søren Dalsgaard, Trine Munk-Olsen, Jiong Li, Rosalind J Wright, Natalie C Momen,

OBJECTIVE:To investigate whether intrauterine exposure to maternal asthma or asthma exacerbations increases the risk of attention-deficit/hyperactivity disorder (ADHD). METHODS:Using Danish register data, this cohort study comprised of 961,202 live singletons born in Denmark during 1997-2012. Children were followed to a maximum of 20.0 years from birth until the first of ADHD-diagnosis/prescription, ... Read more >>

Brain Behav Immun (Brain, behavior, and immunity)
[2019, 82:302-308]

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Maternal childhood and lifetime traumatic life events and infant bronchiolitis.

Margaret A Adgent, Omar Elsayed-Ali, Tebeb Gebretsadik, Frances A Tylavsky, Mehmet Kocak, Stephania A Cormier, Rosalind J Wright, Kecia N Carroll,

BACKGROUND:Viral bronchiolitis is a common respiratory infection that often affects term, otherwise healthy infants. A small literature suggests maternal stress during pregnancy is associated with bronchiolitis. However, the association between maternal exposure to lifetime traumatic stress, including traumatic events occurring in childhood or throughout the life course, and bronchiolitis has ... Read more >>

Paediatr Perinat Epidemiol (Paediatric and perinatal epidemiology)
[2019, 33(4):262-270]

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Prenatal salivary sex hormone levels and birth-weight-for-gestational age.

Katherine Svensson, Allan C Just, Abby F Fleisch, Alison P Sanders, Marcela Tamayo-Ortiz, Andrea A Baccarelli, Rosalind J Wright, Martha M Téllez-Rojo, Robert O Wright, Heather H Burris,

OBJECTIVE:To determine whether prenatal sex hormones from maternal saliva are associated with birth-weight-for-gestational age. STUDY DESIGN:We measured salivary progesterone, testosterone, estradiol, dehydroepiandrosterone (DHEA), and cortisone in 504 pregnant women in a Mexico City cohort. We performed linear and modified Poisson regression to examine associations of log-transformed hormones with birth-weight-for-gestational age ... Read more >>

J Perinatol (Journal of perinatology : official journal of the California Perinatal Association)
[2019, 39(7):941-948]

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Differential Effects of Stress Exposures, Caregiving Quality, and Temperament in Early Life on Working Memory versus Inhibitory Control in Preschool-Aged Children.

Michelle Bosquet Enlow, Carter R Petty, Cassandra Svelnys, Michaela Gusman, Michelle Huezo, Ashley Malin, Rosalind J Wright,

We examined the roles of maternal and child lifetime stress exposures, infant temperament (orienting/regulation, surgency/extraversion), and maternal caregiving during infancy and preschool on preschoolers' working memory and inhibitory control in a sociodemographically diverse pregnancy cohort. Working memory was predicted by infant orienting/regulation, with differential effects by the level of maternal ... Read more >>

Dev Neuropsychol (Developmental neuropsychology)
[2019, 44(4):339-356]

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Antenatal active maternal asthma and other atopic disorders is associated with ADHD behaviors among school-aged children.

Whitney J Cowell, David C Bellinger, Robert O Wright, Rosalind J Wright,

BACKGROUND:Identifying modifiable risk factors for neuropsychological correlates of attention deficit hyperactivity disorder (ADHD) in early childhood can inform prevention strategies. Prenatal inflammatory states, such as maternal asthma and other atopic disorders, have been increasingly linked to enhanced risk for neurobehavioral disorders in children, with some studies suggesting sex-specific effects. OBJECTIVES:To ... Read more >>

Brain Behav Immun (Brain, behavior, and immunity)
[2019, 80:871-878]

Cited: 1 time

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Sex-specific associations between prenatal negative life events and birth outcomes.

Maria José Rosa, Farida Nentin, Michelle Bosquet Enlow, Michele R Hacker, Nastasia Pollas, Brent Coull, Rosalind J Wright,

Maternal psychosocial stress can negatively impact gestational length and development of the fetus. These effects may be sex-specific but have not been extensively studied. The objective of this study was to examine the associations between prenatal maternal stress and birth outcomes and whether effects are modified by sex. Prenatal maternal ... Read more >>

Stress (Stress (Amsterdam, Netherlands))
[2019, 22(6):647-653]

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Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Leanne K Küpers, Claire Monnereau, Gemma C Sharp, Paul Yousefi, Lucas A Salas, Akram Ghantous, Christian M Page, Sarah E Reese, Allen J Wilcox, Darina Czamara, Anne P Starling, Alexei Novoloaca, Samantha Lent, Ritu Roy, Cathrine Hoyo, Carrie V Breton, Catherine Allard, Allan C Just, Kelly M Bakulski, John W Holloway, Todd M Everson, Cheng-Jian Xu, Rae-Chi Huang, Diana A van der Plaat, Matthias Wielscher, Simon Kebede Merid, Vilhelmina Ullemar, Faisal I Rezwan, Jari Lahti, Jenny van Dongen, Sabine A S Langie, Tom G Richardson, Maria C Magnus, Ellen A Nohr, Zongli Xu, Liesbeth Duijts, Shanshan Zhao, Weiming Zhang, Michelle Plusquin, Dawn L DeMeo, Olivia Solomon, Joosje H Heimovaara, Dereje D Jima, Lu Gao, Mariona Bustamante, Patrice Perron, Robert O Wright, Irva Hertz-Picciotto, Hongmei Zhang, Margaret R Karagas, Ulrike Gehring, Carmen J Marsit, Lawrence J Beilin, Judith M Vonk, Marjo-Riitta Jarvelin, Anna Bergström, Anne K Örtqvist, Susan Ewart, Pia M Villa, Sophie E Moore, Gonneke Willemsen, Arnout R L Standaert, Siri E Håberg, Thorkild I A Sørensen, Jack A Taylor, Katri Räikkönen, Ivana V Yang, Katerina Kechris, Tim S Nawrot, Matt J Silver, Yun Yun Gong, Lorenzo Richiardi, Manolis Kogevinas, Augusto A Litonjua, Brenda Eskenazi, Karen Huen, Hamdi Mbarek, Rachel L Maguire, Terence Dwyer, Martine Vrijheid, Luigi Bouchard, Andrea A Baccarelli, Lisa A Croen, Wilfried Karmaus, Denise Anderson, Maaike de Vries, Sylvain Sebert, Juha Kere, Robert Karlsson, Syed Hasan Arshad, Esa Hämäläinen, Michael N Routledge, Dorret I Boomsma, Andrew P Feinberg, Craig J Newschaffer, Eva Govarts, Matthieu Moisse, M Daniele Fallin, Erik Melén, Andrew M Prentice, Eero Kajantie, Catarina Almqvist, Emily Oken, Dana Dabelea, H Marike Boezen, Phillip E Melton, Rosalind J Wright, Gerard H Koppelman, Letizia Trevisi, Marie-France Hivert, Jordi Sunyer, Monica C Munthe-Kaas, Susan K Murphy, Eva Corpeleijn, Joseph Wiemels, Nina Holland, Zdenko Herceg, Elisabeth B Binder, George Davey Smith, Vincent W V Jaddoe, Rolv T Lie, Wenche Nystad, Stephanie J London, Debbie A Lawlor, Caroline L Relton, Harold Snieder, Janine F Felix,

Birthweight is associated with health outcomes across the life course, DNA methylation may be an underlying mechanism. In this meta-analysis of epigenome-wide association studies of 8,825 neonates from 24 birth cohorts in the Pregnancy And Childhood Epigenetics Consortium, we find that DNA methylation in neonatal blood is associated with birthweight ... Read more >>

Nat Commun (Nature communications)
[2019, 10(1):1893]

Cited: 8 times

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