Full Text Journal Articles by
Author Romain Mathieu

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[Renal carcinoma with leiomyomatous stroma and osseous metaplasia from a patient diagnosed with a tuberous sclerosis complex].

Camille Gandon, Marjorie Gournay, Frédéric Dugay, Karim Bensalah, Romain Mathieu, Grégory Verhoest, Benoît Peyronnet, Marc-Antoine Belaud-Rotureau, Nathalie Rioux-Leclercq, Solène-Florence Kammerer-Jacquet,

Renal cell carcinoma with leiomyomatous stroma is a rare and poorly described histopathological entity. Here we report a unique case with osseous metaplasia, in a 31-year-old man recently diagnosed with a tuberous sclerosis complex (TSC2 gene mutation). Partial nephrectomy was performed. Histologically, the epithelial component was made up of papillary and ... Read more >>

Ann Pathol (Annales de pathologie)
[2021, :]

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Tissue cholesterol metabolism and prostate cancer aggressiveness: Ethno-geographic variations.

Vincent Lethongsavarn, Michèle Pinault, Abdoulaye Diedhiou, Cyrille Guimaraes, Roseline Guibon, Franck Bruyère, Romain Mathieu, Nathalie Rioux-Leclercq, Luc Multigner, Laurent Brureau, Georges Fournier, Laurent Doucet, P Blanchet, Gaëlle Fromont,

<h4>Background</h4>Prostate cancer (PCa) is more frequent and more aggressive in populations of African descent than in Caucasians. Since the fatty acid composition of peri-prostatic adipose tissue (PPAT) has been shown to differ according to the ethno-geographic origin and is involved in PCa aggressiveness, we aimed to analyze the cholesterol content ... Read more >>

Prostate (The Prostate)
[2021, :]

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Towards a Reduced In Silico Model Predicting Biochemical Recurrence After Radiotherapy in Prostate Cancer.

Carlos Sosa-Marrero, Renaud de Crevoisier, Alfredo Hernandez, Pierre Fontaine, Nathalie Rioux-Leclercq, Romain Mathieu, Alain Fautrel, Francois Paris, Oscar Acosta,

<h4>Objective</h4>Purposes of this work were i) to develop an in silico model of tumor response to radiotherapy, ii) to perform an exhaustive sensitivity analysis in order to iii) propose a simplified version and iv) to predict biochemical recurrence with both the comprehensive and the reduced model.<h4>Methods</h4>A multiscale computational model of ... Read more >>

IEEE Trans Biomed Eng (IEEE transactions on bio-medical engineering)
[2021, 68(9):2718-2729]

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Biomarker in Active Surveillance for Prostate Cancer: A Systematic Review.

Cécile Manceau, Gaëlle Fromont, Jean-Baptiste Beauval, Eric Barret, Laurent Brureau, Gilles Créhange, Charles Dariane, Gaëlle Fiard, Mathieu Gauthé, Romain Mathieu, Raphaële Renard-Penna, Guilhem Roubaud, Alain Ruffion, Paul Sargos, Morgan Rouprêt, Guillaume Ploussard, On Behalf Of The Cc-Afu Cancerology Committee Of The Association Française d'Urologie,

Active surveillance (AS) in prostate cancer (PCa) represents a curative alternative for men with localised low-risk PCa. Continuous improvement of AS patient's selection and surveillance modalities aims at reducing misclassification, simplifying modalities of surveillance and decreasing need for invasive procedures such repeated biopsies. Biomarkers represent interesting tools to evaluate PCa ... Read more >>

Cancers (Basel) (Cancers)
[2021, 13(17):]

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Metastatic clear cell renal cell carcinoma: computed tomography texture analysis as predictive biomarkers of survival in patients treated with nivolumab.

Zine-Eddine Khene, Romain Kokorian, Romain Mathieu, Anis Gasmi, Rioux-Leclercq Nathalie, Kammerer-Jacquet Solène-Florence, Shahrokh Shariat, Renaud de Crevoisier, Brigitte Laguerre, Karim Bensalah,

<h4>Introduction</h4>To evaluate the value of image-based texture analysis for predicting progression-free survival (PFS) and overall survival (OS) in patients with metastatic clear cell renal carcinoma (cCCR) treated with nivolumab.<h4>Methods</h4>This retrospective study included 48 patients with metastatic cCCR treated with nivolumab. Nivolumab was used as a second- or third-line monotherapy. Texture ... Read more >>

Int J Clin Oncol (International journal of clinical oncology)
[2021, :]

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Hospitalization for adverse events under abiraterone or enzalutamide exposure in real-world setting: A French population-based study on prostate cancer patients.

Lucie-Marie Scailteux, Fabien Despas, Frédéric Balusson, Boris Campillo-Gimenez, Romain Mathieu, Sébastien Vincendeau, André Happe, Emmanuel Nowak, Sandrine Kerbrat, Emmanuel Oger,

<h4>Aims</h4>Safety profiles of abiraterone and enzalutamide rely mainly on Phase III clinical trials. Our objective was to estimate the incidence rate ratio (IRR) for certain adverse events leading in real life to hospitalization (atrial fibrillation, acute heart failure, ischaemic heart disease, acute kidney injury [AKI], ischaemic stroke, torsade de pointe/QT ... Read more >>

Br J Clin Pharmacol (British journal of clinical pharmacology)
[2021, :]

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Radiogenomics in prostate cancer evaluation.

Ronan Thenault, Anis Gasmi, Zine-Edine Khene, Karim Bensalah, Romain Mathieu,

<h4>Purpose of review</h4>Radiogenomics, fusion between radiomics and genomics, represents a new field of research to improve cancer comprehension and evaluation. In this review, we give an overview of radiogenomics and its most recent and relevant applications in prostate cancer management.<h4>Recent findings</h4>Literature about radiogenomics in prostate cancer emerged last 5 years ... Read more >>

Curr Opin Urol (Current opinion in urology)
[2021, 31(4):424-429]

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Changes in prostate cancer screening practice by blood PSA testing between 2011 and 2017, a French population-based study.

Lucie-Marie Scailteux, Valérian Capelle, Frédéric Balusson, Emmanuel Oger, Sébastien Vincendeau, Romain Mathieu, Anthony Chapron,

<h4>Objective</h4>The aim of the study was to determine the trend of first blood prostate-specific antigen (PSA) test prescription in France between 2011 and 2017, based on the assumption that prostate cancer (PCa) screening is expected to decline over the years.<h4>Method</h4>Using a representative sample of the French population from the French ... Read more >>

Curr Med Res Opin (Current medical research and opinion)
[2021, 37(8):1435-1441]

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Impact of Hospital volume on postoperative outcomes after radical prostatectomy: A 5-Year nationwide database analysis.

Guillaume Ploussard, Annabelle Grabia, Jean-Baptiste Beauval, Romain Mathieu, Laurent Brureau, François Rozet, Morgan Rouprêt, Charles-Edouard Lequeu, ,

<h4>Background</h4>Hospital volume is considered to be a quality measure for outcomes after major oncological surgery. However, countrywide data are lacking for radical prostatectomy (RP).<h4>Objective</h4>To assess the impact of hospital volume on postoperative outcomes after RP performed using an open (ORP) versus a minimally invasive surgery (MIS, including pure and robot-assisted ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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Prognostic value of the systemic immune-inflammation index in non-muscle invasive bladder cancer.

Satoshi Katayama, Keiichiro Mori, Benjamin Pradere, Ekaterina Laukhtina, Victor M Schuettfort, Fahad Quhal, Reza Sari Motlagh, Hadi Mostafaei, Nico C Grossmann, Pawel Rajwa, Marco Moschini, Romain Mathieu, Mohammad Abufaraj, David D'Andrea, Eva Compérat, Martin Haydter, Shin Egawa, Yasutomo Nasu, Shahrokh F Shariat, ,

<h4>Purpose</h4>We assessed the prognostic value of systemic immune-inflammation index (SII) to refine risk stratification of the heterogeneous spectrum of patients with non-muscle-invasive bladder cancer (NMIBC) METHODS: In this multi-institutional cohort, preoperative blood-based SII was retrospectively assessed in 1117 patients with NMIBC who underwent transurethral resection of bladder (TURB) between 1996 ... Read more >>

World J Urol (World journal of urology)
[2021, :]

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The role of lymph node dissection in salvage radical prostatectomy for patients with radiation recurrent prostate cancer.

Fahad Quhal, Pawel Rajwa, Keiichiro Mori, Ekaterina Laukhtina, Nico C Grossmann, Victor M Schuettfort, Frederik König, Abdulmajeed Aydh, Reza S Motlagh, Satoshi Katayama, Hadi Mostafai, Benjamin Pradere, Giancarlo Marra, Paolo Gontero, Romain Mathieu, Pierre I Karakiewicz, Alberto Briganti, Shahrokh F Shariat, Axel Heidenreich,

<h4>Purpose</h4>To examine the effect of lymph node dissection on the outcomes of patients who underwent salvage radical prostatectomy (SRP).<h4>Material and methods</h4>We retrospectively reviewed data from radiation-recurrent patients with prostate cancer (PCa) who underwent SRP from 2000-2016. None of the patients had clinical lymph node involvement before SRP. The effect of ... Read more >>

Prostate (The Prostate)
[2021, 81(11):765-771]

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Pretreatment Risk Stratification for Endoscopic Kidney-sparing Surgery in Upper Tract Urothelial Carcinoma: An International Collaborative Study.

Beat Foerster, Mohammad Abufaraj, Surena F Matin, Mounsif Azizi, Mohit Gupta, Wei-Ming Li, Thomas Seisen, Timothy Clinton, Evanguelos Xylinas, M Carmen Mir, Donald Schweitzer, Andrea Mari, Shoji Kimura, Marco Bandini, Romain Mathieu, Ja H Ku, Gautier Marcq, Georgi Guruli, Markus Grabbert, Anna K Czech, Tim Muilwijk, Armin Pycha, David D'Andrea, Firas G Petros, Philippe E Spiess, Trinity Bivalacqua, Wen-Jeng Wu, Morgan Rouprêt, Laura-Maria Krabbe, Kees Hendricksen, Shin Egawa, Alberto Briganti, Marco Moschini, Vivien Graffeille, Wassim Kassouf, Riccardo Autorino, Axel Heidenreich, Piotr Chlosta, Steven Joniau, Francesco Soria, Phillip M Pierorazio, Shahrokh F Shariat,

<h4>Background</h4>Several groups have proposed features to identify low-risk patients who may benefit from endoscopic kidney-sparing surgery in upper tract urothelial carcinoma (UTUC).<h4>Objective</h4>To evaluate standard risk stratification features, develop an optimal model to identify ≥pT2/N+ stage at radical nephroureterectomy (RNU), and compare it with the existing unvalidated models.<h4>Design, setting, and participants</h4>This ... Read more >>

Eur Urol (European urology)
[2021, 80(4):507-515]

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Predicting Complications After Robotic Partial Nephrectomy: Back to Simplicity.

Zine-Eddine Khene, Clément Mazouin, Alessandro Larcher, Benoit Peyronnet, Anis Gasmi, Mathieu Roumiguié, Grégory Verhoest, Umberto Capitanio, Romain Mathieu, Nicolas Doumerc, Francesco Montorsi, Karim Bensalah,

<h4>Background</h4>Robotic partial nephrectomy (RPN) has a significant morbidity. Nephrometry scores have been described to predict the occurrence of complications. Their usefulness is debated.<h4>Objective</h4>To evaluate the clinical utility of three nephrometry scores (radius, exophytic/endophytic, nearness, anterior/posterior, location [RENAL], preoperative aspects and dimensions used for an anatomical [PADUA], and simplified PADUA Renal ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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Novel Classification for Upper Tract Urothelial Carcinoma to Better Risk-stratify Patients Eligible for Kidney-sparing Strategies: An International Collaborative Study.

Gautier Marcq, Beat Foerster, Mohammad Abufaraj, Surena F Matin, Mounsif Azizi, Mohit Gupta, Wei-Ming Li, Thomas Seisen, Timothy Clinton, Evanguelos Xylinas, M Carmen Mir, Donald Schweitzer, Andrea Mari, Shoji Kimura, Marco Bandini, Romain Mathieu, Ja H Ku, Georgi Guruli, Markus Grabbert, Anna K Czech, Tim Muilwijk, Armin Pycha, David D'Andrea, Firas G Petros, Philippe E Spiess, Trinity Bivalacqua, Wen-Jeng Wu, Morgan Rouprêt, Laura-Maria Krabbe, Kees Hendricksen, Shin Egawa, Alberto Briganti, Marco Moschini, Vivien Graffeille, Riccardo Autorino, Patricia John, Axel Heidenreich, Piotr Chlosta, Steven Joniau, Francesco Soria, Phillip M Pierorazio, Shahrokh F Shariat, Wassim Kassouf,

<h4>Background</h4>The European Association of Urology risk stratification dichotomizes patients with upper tract urothelial carcinoma (UTUC) into two risk categories.<h4>Objective</h4>To evaluate the predictive value of a new classification to better risk stratify patients eligible for kidney-sparing surgery (KSS).<h4>Design, setting, and participants</h4>This was a retrospective study including 1214 patients from 21 centers ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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Propensity-score analysis comparing perioperative and functional outcomes between XPS 180 W-photovaporization and GreenLight laser enucleation of the prostate: reasons to discard vaporization and move to enucleation.

Anis Gasmi, Zine-Eddine Khene, Sonia Guérin, Karim Bensalah, Benoit Peyronnet, Romain Mathieu, Morgan Roupret, Enrique Rijo, Benjamin Pradère, Vincent Misrai,

<h4>Purpose</h4>To compare the perioperative and functional outcomes between 180_W XPS GreenLight photoselective vaporization (PVP) and 532-nm GreenLight laser enucleation of the prostate (GreenLEP) in the surgical management of benign prostatic obstruction (BPO).<h4>Methods</h4>Retrospective review of a prospectively maintained international database of patients managed with GreenLight laser surgery (PVP or GreenLEP) was ... Read more >>

World J Urol (World journal of urology)
[2021, 39(7):2269-2276]

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Complete Transurethral Resection before Radical Cystectomy May Improve Oncological Outcomes.

Vivien Graffeille, Grégory Verhoest, Alexandre Gryn, Solène-Florence Kammerer-Jacquet, Quentin Alimi, Jean-Baptiste Beauval, Luc Beuzit, Benjamin Pradère, Matthieu Thoulouzan, Zine Eddine Khene, François Guille, Nathalie Rioux-Leclercq, Romain Mathieu, Xavier Gamé, Karim Bensalah, Michel Soulié, Mathieu Roumiguié, Benoit Peyronnet,

<h4>Objectives</h4>The objective of this study was to assess the impact of complete transurethral resection of bladder tumors (TURBTs) before radical cystectomy on pathological and oncological outcomes of patients with muscle-invasive bladder cancer (MIBC) and high-risk non-MIBC.<h4>Materials and methods</h4>The charts of all patients who underwent radical cystectomy for bladder cancer in ... Read more >>

Urol Int (Urologia internationalis)
[2021, :1-8]

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Overall Survival Among Chemotherapy-Naive Patients With Castration-Resistant Prostate Cancer Under Abiraterone Versus Enzalutamide: A Direct Comparison Based on a 2014-2018 French Population Study (the SPEAR Cohort).

Lucie-Marie Scailteux, Boris Campillo-Gimenez, Sandrine Kerbrat, Fabien Despas, Romain Mathieu, Sébastien Vincendeau, Frédéric Balusson, André Happe, Emmanuel Nowak, Emmanuel Oger,

Abiraterone acetate (ABI) and enzalutamide (ENZ) are considered to be clinically relevant comparators among chemotherapy-naive patients with castration-resistant prostate cancer. No clinical trials comparing overall survival with ABI versus ENZ in a head-to-head approach have been published so far. A few observational studies with low power suggested a potential benefit ... Read more >>

Am J Epidemiol (American journal of epidemiology)
[2021, 190(3):413-422]

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Adherent perinephric fat affects perioperative outcomes after partial nephrectomy: a systematic review and meta-analysis.

Zine-Eddine Khene, Gilles Dosin, Benoit Peyronnet, Anis Gasmi, Nicolas Doumerc, Idir Ouzaid, Benjamin Pradere, Marie Brassier, Mathieu Roumiguié, Romain Mathieu, Nathalie Rioux-Leclercq, Jay D Raman, Shahrokh Shariat, Karim Bensalah,

To investigate the association of adherent perinephric fat (APF) with perioperative outcomes, we conducted a systematic review and meta-analysis of the literature to clarify the impact of APF in patients undergoing partial nephrectomy. A systematic literature search using the Medline, Scopus, and Cochrane databases was performed in April 2019 and ... Read more >>

Int J Clin Oncol (International journal of clinical oncology)
[2021, 26(4):636-646]

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Combined RNA/tissue profiling identifies novel Cancer/testis genes.

Soazik P Jamin, Feria Hikmet, Romain Mathieu, Bernard Jégou, Cecilia Lindskog, Frédéric Chalmel, Michael Primig,

Cancer/Testis (CT) genes are induced in germ cells, repressed in somatic cells, and derepressed in somatic tumors, where these genes can contribute to cancer progression. CT gene identification requires data obtained using standardized protocols and technologies. This is a challenge because data for germ cells, gonads, normal somatic tissues, and ... Read more >>

Mol Oncol (Molecular oncology)
[2021, :]

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Apalutamide, darolutamide and enzalutamide in nonmetastatic castration-resistant prostate cancer: a meta-analysis.

Mathieu Roumiguié, Xavier Paoletti, Yann Neuzillet, Romain Mathieu, Sebastien Vincendeau, François Kleinclauss, Arnaud Mejean, Laurent Guy, Marc Olivier Timsit, Thierry Lebret,

<b>Aim:</b> Comparison of the efficacy/safety/health-related quality of life of apalutamide, enzalutamide and darolutamide in Phase III clinical trials involving patients with nonmetastatic castration-resistant prostate cancer was performed. <b>Materials & methods:</b> Relevant studies were identified by searching PubMed as well as conference abstracts reporting updated overall survival. Three pivotal trials were identified, SPARTAN (apalutamide), PROSPER ... Read more >>

Future Oncol (Future oncology (London, England))
[2021, 17(14):1811-1823]

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A Systematic Review of the Emerging Role of Immune Checkpoint Inhibitors in Metastatic Castration-resistant Prostate Cancer: Will Combination Strategies Improve Efficacy?

Isabel Heidegger, Andrea Necchi, Andreas Pircher, Igor Tsaur, Giancarlo Marra, Veeru Kasivisvanathan, Alexander Kretschmer, Romain Mathieu, Francesco Ceci, Roderick C N van den Bergh, Constance Thibault, Derya Tilki, Massimo Valerio, Christian Surcel, Giorgio Gandaglia, ,

<h4>Context</h4>The role of immune checkpoint inhibition (ICI) in the treatment of prostate cancer (PC) still remains elusive. It has been proposed that combination of ICI with other molecules increases the efficacy of immunotherapy in PC.<h4>Objective</h4>To systematically review the literature to assess the potential role of ICI in combination with additional ... Read more >>

Eur Urol Oncol (European urology oncology)
[2020, :]

Cited: 3 times

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Comparing oncological outcomes of laparoscopic vs open radical nephroureterectomy for the treatment of upper tract urothelial carcinoma: A propensity score-matched analysis.

Marco Moschini, Stefania Zamboni, Luca Afferi, Benjamin Pradere, Mohammad Abufaraj, Francesco Soria, David D'Andrea, Morgan Roupret, Alexandre De la Taille, Claudio Simeone, Agostino Mattei, Romain Mathieu, Karim Bensalah, Manfred Peter Wirth, Francesco Montorsi, Alberto Briganti, Andrea Gallina, Giuseppe Simone, Michele Gallucci, Carlo Di Bona, Giancarlo Marra, Andrea Mari, Ettore Di Trapani, Mario Alvarez Maestro, Wojciech Krajewski, Shahrokh F Shariat, Evanguelos Xylinas, Philipp Baumeister,

<h4>Objectives</h4>To compare oncological outcomes of open (ORNU) and laparoscopic radical nephroureterectomy (LRNU) after controlling for preoperative patient-derived factors.<h4>Patients and methods</h4>We evaluated a multi-institutional collaborative database composed of 3984 patients diagnosed with upper tract urothelial carcinoma (UTUC) treated with RNU between 2006 and 2018. To adjust for potential selection bias, propensity ... Read more >>

Arab J Urol (Arab journal of urology)
[2020, 19(1):31-36]

Cited: 2 times

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Developmental changes in size effects for simple tie and non-tie addition problems in 6- to 12-year-old children and adults.

Jeanne Bagnoud, Jasinta Dewi, Caroline Castel, Romain Mathieu, Catherine Thevenot,

In the domain of cognitive arithmetic, the size effect corresponds to an increase in solution times as a function of the size of the operands involved in the problems. In this study, we tracked the evolution of size effects associated with tie and non-tie addition problems across development. We scrutinized ... Read more >>

J Exp Child Psychol (Journal of experimental child psychology)
[2021, 201:104987]

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Renal cell carcinoma with leiomyomatous stroma in tuberous sclerosis complex: a distinct entity.

Marjorie Gournay, Frédéric Dugay, Marc-Antoine Belaud-Rotureau, Benoit Peyronnet, Romain Mathieu, Gregory Verhoest, Karim Bensalah, Sylvie Odent, Philippe Denizeau, Cécile Vigneau, Aurélien Morini, Nathalie Rioux-Leclercq, Solène-Florence Kammerer-Jacquet,

Renal cell carcinoma with leiomyomatous stroma (RCCLS) is an emerging entity frequently associated with tuberous sclerosis complex (TSC). We described herein a series of RCCLS in TSC patients at pathological and cytogenetic levels. Three male patients with TSC and RCCLS were identified between 2000 and 2019 at the University Hospital ... Read more >>

Virchows Arch (Virchows Archiv : an international journal of pathology)
[2021, 478(4):793-799]

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Management of Patients with Node-positive Prostate Cancer at Radical Prostatectomy and Pelvic Lymph Node Dissection: A Systematic Review.

Giancarlo Marra, Massimo Valerio, Isabel Heidegger, Igor Tsaur, Romain Mathieu, Francesco Ceci, Guillaume Ploussard, Roderick C N van den Bergh, Alexander Kretschmer, Constance Thibault, Piet Ost, Derya Tilki, Veeru Kasivisvanathan, Marco Moschini, Rafael Sanchez-Salas, Paolo Gontero, R Jeffrey Karnes, Francesco Montorsi, Giorgio Gandaglia, ,

<h4>Context</h4>Optimal management of prostate cancer (PCa) patients with lymph node invasion at radical prostatectomy and pelvic lymph node dissection still remains unclear.<h4>Objective</h4>To assess the effectiveness of postoperative treatment strategies for pathologically node-positive PCa patients. The secondary aim was to identify the most relevant prognostic factors to guide the management of ... Read more >>

Eur Urol Oncol (European urology oncology)
[2020, 3(5):565-581]

Cited: 4 times

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