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Author Roderick Tung

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Left Bundle Branch Block: Characterization, Definitions, and Recent Insights into Conduction System Physiology.

Margarida Pujol-López, José M Tolosana, Gaurav A Upadhyay, Lluís Mont, Roderick Tung,

Left bundle branch block (LBBB) is not just a simple electrocardiogram alteration. The intricacies of this general terminology go beyond simple conduction block. This review puts together current knowledge on the historical concept of LBBB, clinical significance, and recent insights into the pathophysiology of human LBBB. LBBB is an entity ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, 13(4):671-684]

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Empiric ablation of polymorphic ventricular tachycardia/fibrillation in the absence of a mappable trigger: Prospective feasibility and efficacy of pacemap matching to defibrillator electrograms.

Pablo Salazar, Andrew Beaser, Gaurav Upadhyay, Zaid Aziz, Stephanie Besser, Dalise Y Shatz, Hemal Nayak, Roderick Tung,

<h4>Background</h4>Catheter ablation strategies for ventricular fibrillation (VF) and polymorphic ventricular tachycardia (PMVT) are not established when spontaneous triggers are rare or absent.<h4>Objective</h4>The purpose of this study was to report the feasibility and efficacy of a novel empiric ablation strategy of pacemapping to stored implantable cardioverter-defibrillator (ICD) template electrograms (SITE) of ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, :]

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Comparison of clinical and echocardiographic features of first and second waves of COVID-19 at a large, tertiary medical center serving a predominantly African American patient population.

Ilya Karagodin, Cristiane Carvalho Singulane, Stephanie A Besser, Amita Singh, Karima Addetia, Jeanne M DeCara, Amit R Patel, R Parker Ward, Roderick Tung, Roberto M Lang,

As clinicians have gained experience in treating patients with the novel SARS-CoV-2 (COVID-19) virus, mortality rates for patients with acute COVID-19 infection have decreased. The Centers for Disease Control (CDC) has identified the African American population as having increased risk of COVID-19 associated mortality, however little is known about echocardiographic ... Read more >>

Int J Cardiovasc Imaging (The international journal of cardiovascular imaging)
[2021, 37(11):3181-3190]

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The Burden of Proof in Defining Conduction Pacing Criteria: Back to Fundamental Electrophysiology.

Roderick Tung, Gaurav A Upadhyay,

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2021, 7(9):1178-1181]

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Impact of physiological pacing on functional mitral regurgitation in systolic dysfunction: Initial echocardiographic remodeling findings after His bundle pacing.

Gaurav A Upadhyay, Michael Henry, Davide Genovese, Parth Desai, Jonathan Lattell, Hannah Wey, Stephanie A Besser, Zaid Aziz, Andrew D Beaser, Cevher Ozcan, Hemal M Nayak, Roberto M Lang, Roderick Tung,

<h4>Background</h4>Although His bundle pacing (HBP) has been shown to improve left ventricular ejection fraction (LVEF), its impact on mitral regurgitation (MR) remains uncertain.<h4>Objectives</h4>The aim of this study was to evaluate change in functional MR after HBP in patients with left ventricular (LV) systolic dysfunction.<h4>Methods</h4>Paired echocardiograms were retrospectively assessed in patients ... Read more >>

Heart Rhythm O2 (Heart rhythm O2)
[2021, 2(5):446-454]

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Atypical pathogens associated with cardiac implantable electronic device infections.

Utkarsh Kohli, Aniruddha Hazra, Ahmed Shahab, Andrew D Beaser, Zaid A Aziz, Gaurav A Upadhyay, Cevher Ozcan, Roderick Tung, Hemal M Nayak,

<h4>Background</h4>Cardiovascular implantable electronic device (CIED) infections are associated with significant morbidity and mortality making the identification of the causative organism critical. The vast majority of CIED infections are caused by Staphylococcal species. CIED infections associated with atypical pathogens are rare and have not been systematically investigated. The objective of this ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2021, 44(9):1549-1561]

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B-PO05-220 SUCCESSFUL ABLATION OF INCESSANT UPPER SEPTAL VT IN A PATIENT WITH CARDIOGENIC SHOCK AND COVID

Ryan Burris, Nathaniel Shatz, Pablo Ignacio Salazar, Andrew Y. Chen, Aalap Narichania, Roderick Tung,

Heart Rhythm (Heart rhythm)
[2021, 18(8):S462-S462]

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Substrate Characterization and Outcomes of Ventricular Tachycardia Ablation in TTN (Titin) Cardiomyopathy: A Multicenter Study.

Andres Enriquez, Jackson Liang, Jeffrey Smietana, Daniele Muser, Pablo Salazar, Rajan Shah, Nitish Badhwar, Frank Bogun, Francis Marchlinski, Fermin Garcia, Adrian Baranchuk, Roderick Tung, Damian Redfearn, Pasquale Santangeli,

[Figure: see text]. ... Read more >>

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2021, 14(9):e010006]

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Refractory Ventricular Tachycardia Originating From an Intracardiac Metastasis Treated With Catheter Ablation.

Pablo Salazar, Andrew Chen, Aalap Narichania, Ryan Burris, Swati Rao, Urooba Nadeem, Roderick Tung,

A 45-year-old man with stage IV melanoma presented with incessant nonsustained wide complex tachycardia. He was found to have a right ventricular intracardiac metastasis that created a nidus for ventricular tachycardia refractory to multiple therapeutic interventions. The patient underwent catheter ablation for this rare indication, with successful arrhythmia control by ... Read more >>

JACC Case Rep (JACC. Case reports)
[2021, 3(9):1231-1235]

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Double loop ventricular tachycardia activation patterns with single loop mechanisms: Asymmetric entrainment responses during "pseudo-figure-of-eight" reentry.

Takuro Nishimura, Gaurav A Upadhyay, Zaid A Aziz, Andrew D Beaser, Dalise Y Shatz, Hemal M Nayak, Roderick Tung,

<h4>Background</h4>The classical paradigm of scar-related reentrant ventricular tachycardia (VT) features a circuit with a double loop figure-of-eight (F8) activation pattern.<h4>Objective</h4>The purpose of this study was to interrogate VT circuits with F8 activation patterns by entrainment mapping to differentiate an active loop from a passive loop.<h4>Methods</h4>Sixty VT circuits with >90% of ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, 18(9):1548-1556]

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Cardioneuroablation for cardioinhibitory vasovagal syncope.

Leah A John, Andin Mullis, Joshua Payne, Roderick Tung, Tolga Aksu, Jeffrey R Winterfield,

<h4>Background</h4>Cardioneuroablation (CNA) is an emerging technique being used to treat patients with cardioinhibitory vasovagal syncope (VVS). We describe a case of CNA in targeting atrial ganglionated plexi (GP) based upon anatomical landmarks and fractionated electrogram (EGM) localization in a patient with cardioinhibitory syncope.<h4>Case presentation</h4>A 20-year-old healthy female presented with malignant ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2021, 32(6):1748-1753]

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Fractionation Mapping of the Ganglionated Plexi for Cardioneuroablation.

Leah A John, Andin Mullis, Joshua Payne, Roderick Tung, Tolga Aksu, Jeffrey R Winterfield,

Cardioneuroablation (CNA) is an emerging technique used to treat patients with vasovagal syncope (VVS). We herein describe a case of CNA targeting the atrial ganglionated plexi (GPs) based upon anatomical landmarks and fractionated electrogram (EGM) localization in a 20-year-old healthy female who presented to our center with malignant VVS and ... Read more >>

J Innov Card Rhythm Manag (The Journal of innovations in cardiac rhythm management)
[2021, 12(4):4473-4476]

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Impact of Wideband Late Gadolinium Enhancement Cardiac Magnetic Resonance Imaging on Device-Related Artifacts in Different Implantable Cardioverter-Defibrillator Types.

Amita Singh, Wensu Chen, Hena N Patel, Nazia Alvi, Keigo Kawaji, Stephanie A Besser, Roderick Tung, Jiangang Zou, Roberto M Lang, Victor Mor-Avi, Amit R Patel,

<h4>Background</h4>Late gadolinium enhancement (LGE) imaging in patients with implantable cardioverter-defibrillators (ICD) is limited by device-related artifacts (DRA). The use of wideband (WB) LGE protocols improves LGE images, but their efficacy with different ICD types is not well known.<h4>Purpose</h4>To assess the effects of WB LGE imaging on DRA in different non-MR ... Read more >>

J Magn Reson Imaging (Journal of magnetic resonance imaging : JMRI)
[2021, 54(4):1257-1265]

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Narrowing the Differential Diagnosis for a Wide Complex Tachycardia.

Andrew Y Chen, Takuro Nishimura, Roderick Tung,

Circulation (Circulation)
[2021, 143(5):503-506]

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Spatial and transmural properties of the reentrant ventricular tachycardia circuit in arrhythmogenic right ventricular cardiomyopathy: Simultaneous epicardial and endocardial recordings.

Ruhong Jiang, Takuro Nishimura, Andrew D Beaser, Zaid A Aziz, Gaurav A Upadhyay, Dalise Y Shatz, Hemal M Nayak, Hongtao Liao, Xianzhang Zhan, Fa Po Chung, Yumei Xue, Shulin Wu, Roderick Tung,

<h4>Background</h4>While advances in the characterization of the structural substrate in arrhythmogenic right ventricular cardiomyopathy (ARVC) have been made, the ventricular tachycardia (VT) circuit remains incompletely described.<h4>Objective</h4>The purpose of this study was to delineate the reentrant VT circuit with simultaneous epicardial and endocardial mapping (SEEM) in ARVC.<h4>Methods</h4>Twenty-three consecutive patients with ARVC ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, 18(6):916-925]

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Catheter ablation of ventricular tachycardia in patients with prior cardiac surgery: An analysis from the International VT Ablation Center Collaborative Group.

Martin Aguilar, Usha B Tedrow, Wendy S Tzou, Roderick Tung, David S Frankel, Pasquale Santangeli, Marmar Vaseghi, T Jared Bunch, Luigi Di Biase, Venkatakrishna N Tholakanahalli, Dhanunjaya Lakkireddy, Timm Dickfeld, J Peter Weiss, Nilesh Mathuria, Pasquale Vergara, Shiro Nakahara, Jason S Bradfield, J David Burkhardt, William G Stevenson, David J Callans, Paolo Della Bella, Andrea Natale, Kalyanam Shivkumar, Francis E Marchlinski, William H Sauer,

<h4>Introduction</h4>Patients with prior cardiac surgery may represent a subgroup of patients with ventricular tachycardia (VT) that may be more difficult to control with catheter ablation.<h4>Methods</h4>We evaluated 1901 patients with ischemic and nonischemic cardiomyopathy who underwent VT ablation at 12 centers. Clinical characteristics and VT radiofrequency ablation procedural outcomes were assessed ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2021, 32(2):409-416]

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Prognostic value of cardiac magnetic resonance septal late gadolinium enhancement patterns for periaortic ventricular tachycardia ablation: Heterogeneity of the anteroseptal substrate in nonischemic cardiomyopathy.

Takuro Nishimura, Hena N Patel, Shuo Wang, Gaurav A Upadhyay, Heather L Smith, Cevher Ozcan, Dalise Y Shatz, Hemal M Nayak, Amit R Patel, Roderick Tung,

<h4>Background</h4>Ventricular tachycardia (VT) from the anteroseptal subtype of nonischemic cardiomyopathy has a high probability of recurrence after catheter ablation.<h4>Objective</h4>The purpose of this study was to determine the predictive value of septal scar patterns by late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) on ablation outcomes in patients with VT arising ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, 18(4):579-588]

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Prevalence of newly diagnosed sarcoidosis in patients with ventricular arrhythmias: a cardiac magnetic resonance and 18F-FDG cardiac PET study.

Kalie Y Kebed, Spencer V Carter, Erin Flatley, R Parker Ward, Joshua D Moss, Daniel E Appelbaum, Amita Singh, Roberto M Lang, Roderick Tung, Amit R Patel,

Cardiac sarcoidosis (CS) is known to be associated with ventricular tachycardia (VT); however, most investigations to date have focused on patients with known extra-cardiac sarcoidosis. The presence of CS is typically evaluated using 18F-fluorodeoxyglucose (18F-FDG) uptake on cardiac positron emission tomography (PET) or late gadolinium enhancement (LGE) on cardiac magnetic ... Read more >>

Int J Cardiovasc Imaging (The international journal of cardiovascular imaging)
[2021, 37(4):1361-1369]

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Indirect and Direct Evidence for 3-D Activation During Left Atrial Flutter: Anatomy of Epicardial Bridging.

Hemal M Nayak, Zaid A Aziz, Agatha Kwasnik, Elliot Lee, Dalise Y Shatz, Rocio Tenorio, Stephanie A Besser, Andrew D Beaser, Cevher Ozcan, Gaurav A Upadhyay, Roderick Tung,

<h4>Objectives</h4>This study sought to describe arrhythmia characteristics using ultra-high density (UHD) mapping of macro-re-entrant left atrial flutter (LAFL) which propagate via epicardial bridging (EB), and highlight regional anatomy that poses challenges to ablation.<h4>Background</h4>Three-dimensional propagation via EB may contribute to the maintenance and complexity of LAFL.<h4>Methods</h4>UHD activation maps of macro-re-entrant LAFL ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2020, 6(14):1812-1823]

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Late presentation of recurrent syncope after permanent pacemaker implantation due to Lead-Header malapposition.

Steven Mazzone, Utkarsh Kohli, Zaid A Aziz, Andrew D Beaser, Gaurav A Upadhyay, Roderick Tung, Hemal M Nayak,

Permanent pacemaker (PPM) malfunction due to electrical connection problems such as a loose set screw or lead-header malapposition is extremely rare. We present a patient with complete heart block (CHB) who had PPM malfunction and recurrent syncope, late (14 months) after initial implantation, which was caused by the ventricular lead ... Read more >>

Indian Pacing Electrophysiol J (Indian pacing and electrophysiology journal)
[2021, 21(2):124-127]

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Circuit Determinants of Ventricular Tachycardia Cycle Length: Characterization of Fast and Unstable Human Ventricular Tachycardia.

Takuro Nishimura, Gaurav A Upadhyay, Zaid A Aziz, Andrew D Beaser, Dalise Y Shatz, Hemal M Nayak, Roderick Tung,

<h4>Background</h4>Fast ventricular tachycardias (VTs) have historically been attributed to shorter path lengths with smaller reentrant circuit dimensions in animal models. The relationship between the dimensions of the reentrant VT circuit and tachycardia cycle length (TCL) has not been examined in humans. This study aimed to analyze the determinants of the ... Read more >>

Circulation (Circulation)
[2021, 143(3):212-226]

Cited: 2 times

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Impact of Micro-, Mini- and Multi-Electrode Mapping on Ventricular Substrate Characterisation.

Benjamin Berte, Katja Zeppenfeld, Roderick Tung,

Accurate substrate characterisation may improve the evolving understanding and treatment of cardiac arrhythmias. During substrate-based ablation techniques, wide practice variations exist with mapping via dedicated multi-electrode catheter or conventional ablation catheters. Recently, newer ablation catheter technology with embedded mapping electrodes have been introduced. This article focuses on the general misconceptions ... Read more >>

Arrhythm Electrophysiol Rev (Arrhythmia & electrophysiology review)
[2020, 9(3):128-135]

Cited: 1 time

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Electrophysiological manifestations of rare supra-ventricular tachycardias with concealed nodo-ventricular fibers.

Wei Wei, Caihua Sang, Sulin Zheng, Roderick Tung, Xunzhang Wang, Yumei Xue, Yuanhong Liang, Shangming Song, Tongbao Liu, Deyong Long, Yang Liu, Jianzeng Dong, Changsheng Ma, Shulin Wu,

<h4>Purpose</h4>To clarify the electrophysiological mechanism of supra-ventricular tachycardias (SVT) with concealed nodo-ventricular (NV) fibers.<h4>Methods</h4>We studied the intra-cardiac electrograms during electrophysiological study (EPS) of three cases of SVT which concerned concealed NV fibers. Electrophysiological maneuvers including right ventricular apex entrainments, RS2 stimuli, adenosine triphosphate injection and so on were done for ... Read more >>

J Interv Card Electrophysiol (Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing)
[2021, 62(1):31-38]

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Direct Epicardial Recordings in the Region of the Septopulmonary Bundle: Anatomy "Behind" Posterior Wall Activation.

Swati Rao, Agatha Kwasnik, Roderick Tung,

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2020, 6(9):1214-1216]

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Long or short postpacing interval response to ventricular tachycardia entrainment: What is the mechanism?

Takuro Nishimura, Roderick Tung,

Heart Rhythm (Heart rhythm)
[2021, 18(2):318-320]

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