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Author Robin M Nance

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Drug and alcohol use among people living with HIV in care in the United States by geographic region.

Heidi M Crane, Robin M Nance, Bridget M Whitney, Stephanie Ruderman, Judith I Tsui, Geetanjali Chander, Mary E McCaul, Bryan Lau, Kenneth H Mayer, D Scott Batey, Steven A Safren, Richard D Moore, Joseph J Eron, Sonia Napravnik, W Chris Mathews, Rob J Fredericksen, Andrew W Hahn, Michael J Mugavero, William B Lober, Michael S Saag, Mari M Kitahata, Joseph A C Delaney,

Substance use in the U.S. varies by geographic region. Opioid prescribing practices and marijuana, heroin, and methamphetamine availability are evolving differently across regions. We examined self-reported substance use among people living with HIV (PLWH) in care at seven sites from 2017-2019 to understand current regional substance use patterns. We calculated ... Read more >>

AIDS Care (AIDS care)
[2021, :1-8]

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Brief Report: Differences in Types of Myocardial Infarctions Among People Aging With HIV.

Heidi M Crane, Robin M Nance, Bridget M Whitney, Susan R Heckbert, Matthew Budoff, Kevin High, Alan Landay, Matthew Feinstein, Richard D Moore, William Christopher Mathews, Katerina Christopoulos, Michael S Saag, Amanda Willig, Joseph J Eron, Mari M Kitahata, Joseph A C Delaney, ,

<h4>Background</h4>Type 1 myocardial infarctions (T1MIs) result from atherosclerotic plaque instability, rupture, and/or erosion. Type 2 MIs (T2MIs) are secondary to causes such as sepsis and cocaine-induced vasospasm resulting in an oxygen demand-supply mismatch and are associated with higher mortality than T1MIs. T2MIs account for a higher proportion of MIs among ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2021, 86(2):208-212]

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Hazardous alcohol use, antiretroviral therapy receipt, and viral suppression in people living with HIV who inject drugs in the United States, India, Russia, and Vietnam.

Jennifer A Wagman, Adriane Wynn, Mika Matsuzaki, Natalia Gnatienko, Lisa R Metsch, Carlos Del Rio, Daniel J Feaster, Robin M Nance, Bridget M Whitney, Joseph A C Delaney, Shoshana Y Kahana, Heidi M Crane, Redonna K Chandler, Jennifer C Elliott, Frederick Altice, Gregory M Lucas, Shruti H Mehta, Yael Hirsch-Moverman, Wafaa M El-Sadr, Quan Vu, Binh Nguyen Thanh, Sandra A Springer, Judith I Tsui, Jeffrey H Samet,

<h4>Objectives</h4>In high-income countries, hazardous alcohol use is associated with reduced receipt of antiretroviral therapy (ART) and viral suppression among people living with HIV (PLHIV) who inject drugs. These associations are less understood in lower middle-income countries (LMIC) and upper middle-income countries.<h4>Design</h4>We examined associations between hazardous alcohol use, ART receipt, and ... Read more >>

AIDS (AIDS (London, England))
[2020, 34(15):2285-2294]

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Substantial decline in heavily treated therapy-experienced persons with HIV with limited antiretroviral treatment options.

Kristina L Bajema, Robin M Nance, Joseph A C Delaney, Ellen Eaton, Thibaut Davy-Mendez, Maile Y Karris, Richard D Moore, Joseph J Eron, Benigno Rodriguez, Kenneth H Mayer, Elvin Geng, Cindy Garris, Michael S Saag, Heidi M Crane, Mari M Kitahata, ,

<h4>Objective</h4>Historically, a high burden of resistance to antiretroviral therapy (ART) in heavily treatment-experienced (HTE) persons with HIV (PWH) resulted in limited treatment options (LTOs). We evaluated the prevalence, risk factors, and virologic control of HTE PWH with LTO throughout the modern ART era.<h4>Design</h4>We examined all ART-experienced PWH in care between ... Read more >>

AIDS (AIDS (London, England))
[2020, 34(14):2051-2059]

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Genetic architecture of cardiometabolic risks in people living with HIV.

Haoxiang Chang, Anshuman Sewda, Carla Marquez-Luna, Sierra R White, Bridget M Whitney, Jessica Williams-Nguyen, Robin M Nance, Won Jun Lee, Mari M Kitahata, Michael S Saag, Amanda Willig, Joseph J Eron, W Christopher Mathews, Peter W Hunt, Richard D Moore, Allison Webel, Kenneth H Mayer, Joseph A Delaney, Paul K Crane, Heidi M Crane, Ke Hao, Inga Peter,

<h4>Background</h4>Advances in antiretroviral therapies have greatly improved the survival of people living with human immunodeficiency virus (HIV) infection (PLWH); yet, PLWH have a higher risk of cardiovascular disease than those without HIV. While numerous genetic loci have been linked to cardiometabolic risk in the general population, genetic predictors of the ... Read more >>

BMC Med (BMC medicine)
[2020, 18(1):288]

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Changing Patterns of Alcohol Use and Probability of Unsuppressed Viral Load Among Treated Patients with HIV Engaged in Routine Care in the United States.

Catherine R Lesko, Robin M Nance, Bryan Lau, Anthony T Fojo, Heidi E Hutton, Joseph A C Delaney, Heidi M Crane, Karen L Cropsey, Kenneth H Mayer, Sonia Napravnik, Elvin Geng, W Christopher Mathews, Mary E McCaul, Geetanjali Chander, ,

We examined HIV viral load non-suppression ([Formula: see text] 200 copies/mL) subsequent to person-periods (3-18 months) bookended by two self-reports of alcohol use on a standardized patient reported outcome assessment among adults in routine HIV care. We examined the relative risk (RR) of non-suppression associated with increases and decreases in alcohol ... Read more >>

AIDS Behav (AIDS and behavior)
[2020, :]

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Association Between Chronic Hepatitis C Virus Infection and Myocardial Infarction Among People Living With HIV in the United States.

Jessica Williams-Nguyen, Stephen E Hawes, Robin M Nance, Sara Lindström, Susan R Heckbert, H Nina Kim, W Chris Mathews, Edward R Cachay, Matt Budoff, Christopher B Hurt, Peter W Hunt, Elvin Geng, Richard D Moore, Michael J Mugavero, Inga Peter, Mari M Kitahata, Michael S Saag, Heidi M Crane, Joseph A Delaney,

Hepatitis C virus (HCV) infection is common among people living with human immunodeficiency virus (PLWH). Extrahepatic manifestations of HCV, including myocardial infarction (MI), are a topic of active research. MI is classified into types, predominantly atheroembolic type 1 MI (T1MI) and supply-demand mismatch type 2 MI (T2MI). We examined the ... Read more >>

Am J Epidemiol (American journal of epidemiology)
[2020, 189(6):554-563]

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Antiretroviral drug class and anaemia risk in the current treatment era among people living with HIV in the USA: a clinical cohort study.

Barbara N Harding, Bridget M Whitney, Robin M Nance, Heidi M Crane, Greer Burkholder, Richard D Moore, W Christopher Mathews, Joseph J Eron, Peter W Hunt, Paul Volberding, Benigno Rodriguez, Kenneth Mayer, Michael S Saag, Mari M Kitahata, Susan R Heckbert, Joseph A C Delaney,

OBJECTIVE:Anaemia is common among people living with HIV (PLWH) and has been associated with certain, often older, antiretroviral medications. Information on current antiretroviral therapy (ART) and anaemia is limited. The objective was to compare the associations between anaemia incidence or haemoglobin change with core ART classes in the current ART ... Read more >>

BMJ Open (BMJ open)
[2020, 10(3):e031487]

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Impact of Abstinence and of Reducing Illicit Drug Use Without Abstinence on Human Immunodeficiency Virus Viral Load.

Robin M Nance, Maria Esther Perez Trejo, Bridget M Whitney, Joseph A C Delaney, Fredrick L Altice, Curt G Beckwith, Geetanjali Chander, Redonna Chandler, Katerina Christopoulous, Chinazo Cunningham, William E Cunningham, Carlos Del Rio, Dennis Donovan, Joseph J Eron, Rob J Fredericksen, Shoshana Kahana, Mari M Kitahata, Richard Kronmal, Irene Kuo, Ann Kurth, W Chris Mathews, Kenneth H Mayer, Richard D Moore, Michael J Mugavero, Lawrence J Ouellet, Vu M Quan, Michael S Saag, Jane M Simoni, Sandra Springer, Lauren Strand, Faye Taxman, Jeremy D Young, Heidi M Crane,

<h4>Background</h4>Substance use is common among people living with human immunodeficiency virus (PLWH) and a barrier to achieving viral suppression. Among PLWH who report illicit drug use, we evaluated associations between HIV viral load (VL) and reduced use of illicit opioids, methamphetamine/crystal, cocaine/crack, and marijuana, regardless of whether or not abstinence ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, 70(5):867-874]

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Self-reported antiretroviral therapy adherence and viral load in criminal justice-involved populations.

William E Cunningham, Robin M Nance, Carol E Golin, Patrick Flynn, Kevin Knight, Curt G Beckwith, Irene Kuo, Anne Spaulding, Faye S Taxman, Fredrick Altice, Joseph A Delaney, Heidi M Crane, Sandra A Springer,

<h4>Background</h4>Self-reported antiretroviral therapy (ART) adherence measures that are associated with plasma viral load (VL) are valuable to clinicians and researchers, but are rarely examined among groups vulnerable to dropping out of care. One-seventh of all those living with HIV pass through incarceration annually and criminal-justice (CJ) involved people living with ... Read more >>

BMC Infect Dis (BMC infectious diseases)
[2019, 19(1):913]

Cited: 1 time

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Mortality following myocardial infarction among HIV-infected persons: the Center for AIDS Research Network Of Integrated Clinical Systems (CNICS).

Matthew J Feinstein, Robin M Nance, J A Chris Delaney, Susan R Heckbert, Matthew J Budoff, Daniel R Drozd, Greer A Burkholder, James H Willig, Michael J Mugavero, William C Mathews, Richard D Moore, Joseph J Eron, Sonia Napravnik, Peter W Hunt, Elvin Geng, Priscilla Hsue, Inga Peter, William B Lober, Kristina Crothers, Carl Grunfeld, Michael S Saag, Mari M Kitahata, Donald M Lloyd-Jones, Heidi M Crane,

<h4>Background</h4>Persons with human immunodeficiency virus (HIV) have higher risks for myocardial infarction (MI) than the general population. This is driven in part by higher type 2 MI (T2MI, due to coronary supply-demand mismatch) rates among persons with HIV (PWH). In the general population, T2MI has higher mortality than type 1 ... Read more >>

BMC Med (BMC medicine)
[2019, 17(1):149]

Cited: 3 times

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Virologic Failure Among People Living With HIV Initiating Dolutegravir-Based Versus Other Recommended Regimens in Real-World Clinical Care Settings.

Robin M Nance, Vani Vannappagari, Kimberly Smith, Catherine B Johannes, Brian Calingaert, Catherine W Saltus, Kenneth H Mayer, Bridget M Whitney, Benigno Rodriguez, Richard D Moore, Joseph J Eron, Elvin Geng, William Christopher Mathews, Michael J Mugavero, Michael S Saag, Mari M Kitahata, Joseph A C Delaney, Heidi M Crane,

<h4>Background</h4>Guidelines for initial antiretroviral treatment (ART) regimens have evolved, with integrase strand transfer inhibitors (INSTIs) increasingly prominent. Research on virologic failure (VF) with INSTI therapy is predominantly from clinical trials not care settings, especially for recently approved medications including dolutegravir. We compared outcomes among people living with HIV (PLWH) who ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2019, 81(5):572-577]

Cited: 4 times

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Association Between Bilirubin, Atazanavir, and Cardiovascular Disease Events Among People Living With HIV Across the United States.

Heidi M Crane, Robin M Nance, Susan R Heckbert, Corey Ritchings, Lisa Rosenblatt, Matthew Budoff, Brian R Wood, David L Tirschwell, H Nina Kim, William C Mathews, Elvin Geng, Richard D Moore, Peter W Hunt, Joseph J Eron, Greer A Burkholder, Daniel R Drozd, Felicia C Chow, Kyra J Becker, Joseph R Zunt, Emily L Ho, Rizwan Kalani, Andrew Huffer, Bridget M Whitney, Michael S Saag, Mari M Kitahata, Joseph A C Delaney,

<h4>Objective</h4>Bilirubin is an antioxidant that may suppress lipid oxidation. Elevated bilirubin is associated with decreased cardiovascular events in HIV-uninfected populations. We examined these associations in people living with HIV (PLWH).<h4>Methods</h4>Potential myocardial infarctions (MIs) and strokes were centrally adjudicated. We examined MI types: type 1 MI (T1MI) from atherosclerotic plaque instability ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2019, 81(5):e141-e147]

Cited: 1 time

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HIV Viral Suppression Trends.

Jane M Simoni, Robin M Nance, Bridget M Whitney, Michael S Saag, Heidi M Crane,

Ann Intern Med (Annals of internal medicine)
[2019, 170(8):582-583]

Cited: 0 times

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Cumulative Human Immunodeficiency Viremia, Antiretroviral Therapy, and Incident Myocardial Infarction.

Joseph A Delaney, Robin M Nance, Bridget M Whitney, Heidi M Crane, Jessica Williams-Nguyen, Mathew J Feinstein, Robert C Kaplan, David B Hanna, Matthew J Budoff, Daniel R Drozd, Greer Burkholder, Michael J Mugavero, William C Mathews, Richard D Moore, Joseph J Eron, Peter W Hunt, Elvin Geng, Michael S Saag, Mari M Kitahata, Susan R Heckbert,

<h4>Background</h4>People living with HIV are at risk of increased myocardial infarction (MI). Cumulative HIV viral load (VL) has been proposed as a better measure of HIV inflammation than other measures of VL, like baseline VL, but its associations with MI are not known.<h4>Methods</h4>The multisite Centers for AIDS Research Network of ... Read more >>

Epidemiology (Epidemiology (Cambridge, Mass.))
[2019, 30(1):69-74]

Cited: 1 time

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Brief Report: Reduced Use of Illicit Substances, Even Without Abstinence, Is Associated With Improved Depressive Symptoms Among People Living With HIV.

Joseph A Delaney, Robin M Nance, Bridget M Whitney, Frederick L Altice, Xinyuan Dong, Maria Esther Perez Trejo, Mika Matsuzaki, Faye S Taxman, Geetanjali Chander, Irene Kuo, Rob Fredericksen, Lauren N Strand, Joseph J Eron, Elvin Geng, Mari M Kitahata, William C Mathews, Kenneth Mayer, Richard D Moore, Michael S Saag, Sandra Springer, Redonna Chandler, Shoshana Kahana, Heidi M Crane,

<h4>Purpose</h4>Substance use is linked with poor outcomes among people living with HIV (PLWH) and is associated with mental health disorders. This analysis examines the impact of decreasing substance use, even without abstinence, on depressive symptoms among PLWH.<h4>Methods</h4>Data are from PLWH enrolled in the Centers for AIDS Research Network of Integrated ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2018, 79(3):283-287]

Cited: 2 times

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Adjudicated Heart Failure in HIV-Infected and Uninfected Men and Women.

Matthew J Feinstein, Alexandra B Steverson, Hongyan Ning, Anna E Pawlowski, Daniel Schneider, Faraz S Ahmad, Jes M Sanders, Arjun Sinha, Robin M Nance, Chad J Achenbach, J A Christopher Delaney, Susan R Heckbert, Sanjiv J Shah, David B Hanna, Priscilla Y Hsue, Gerald S Bloomfield, Chris T Longenecker, Heidi M Crane, Donald M Lloyd-Jones,

Background HIV is associated with elevated risk of heart failure ( HF ). Despite poor agreement between automated, administrative code-based HF definitions and physician-adjudicated HF , no studies have evaluated incident adjudicated HF for people living with HIV ( PLWH ). Methods and Results We analyzed PLWH and uninfected controls ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2018, 7(21):e009985]

Cited: 6 times

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Accuracy of electronic health record data for the diagnosis of chronic obstructive pulmonary disease in persons living with HIV and uninfected persons.

Kristina Crothers, Carla V Rodriguez, Robin M Nance, Kathleen Akgun, Shahida Shahrir, Joon Kim, Guy W Soo Hoo, Amir Sharafkhaneh, Heidi M Crane, Amy C Justice,

<h4>Purpose</h4>No prior studies have addressed the performance of electronic health record (EHR) data to diagnose chronic obstructive pulmonary disease (COPD) in people living with HIV (PLWH), in whom COPD could be more likely to be underdiagnosed or misdiagnosed, given the higher frequency of respiratory symptoms and smoking compared with HIV-uninfected ... Read more >>

Pharmacoepidemiol Drug Saf (Pharmacoepidemiology and drug safety)
[2019, 28(2):140-147]

Cited: 1 time

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HIV Viral Suppression Trends Over Time Among HIV-Infected Patients Receiving Care in the United States, 1997 to 2015: A Cohort Study.

Robin M Nance, J A Chris Delaney, Jane M Simoni, Ira B Wilson, Kenneth H Mayer, Bridget M Whitney, Frances M Aunon, Steven A Safren, Michael J Mugavero, W Christopher Mathews, Katerina A Christopoulos, Joseph J Eron, Sonia Napravnik, Richard D Moore, Benigno Rodriguez, Bryan Lau, Rob J Fredericksen, Michael S Saag, Mari M Kitahata, Heidi M Crane,

Background:Because HIV viral suppression is essential for optimal outcomes and prevention efforts, understanding trends and predictors is imperative to inform public health policy. Objective:To evaluate viral suppression trends in people living with HIV (PLWH), including the relationship of associated factors, such as demographic characteristics and integrase strand transfer inhibitor (ISTI) ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2018, 169(6):376-384]

Cited: 15 times

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Differentiation of Type 1 and Type 2 Myocardial Infarctions Among HIV-Infected Patients Requires Adjudication Due to Overlap in Risk Factors.

Robin M Nance, Heidi M Crane, Corey Ritchings, Lisa Rosenblatt, Matthew Budoff, Susan R Heckbert, Daniel R Drozd, William C Mathews, Elvin Geng, Peter W Hunt, Matthew J Feinstein, Richard D Moore, Priscilla Hsue, Joseph J Eron, Greer A Burkholder, Benigno Rodriguez, Michael J Mugavero, Michael S Saag, Mari M Kitahata, Joseph A C Delaney,

The Universal Myocardial infarction (MI) definition divides MIs into different types. Type 1 MIs (T1MI) result spontaneously from atherosclerotic plaque instability. Type 2 MIs (T2MI) are due to secondary causes of myocardial oxygen demand/supply mismatch such as occurs with sepsis. T2MI are much more common among those with HIV than ... Read more >>

AIDS Res Hum Retroviruses (AIDS research and human retroviruses)
[2018, 34(11):916-921]

Cited: 0 times

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HIV Provider Documentation and Actions Following Patient Reports of At-risk Behaviors and Conditions When Identified by a Web-Based Point-of-Care Assessment.

Heidi M Crane, Paul K Crane, James T Tufano, James D Ralston, Ira B Wilson, Tyler D Brown, Thomas E Davis, Laurie F Smith, William B Lober, Justin McReynolds, Shireesha Dhanireddy, Robert D Harrington, Carla V Rodriguez, Robin M Nance, Joseph A C Delaney, Steven A Safren, Mari M Kitahata, Rob J Fredericksen,

We compared same-day provider medical record documentation and interventions addressing depression and risk behaviors before and after delivering point-of-care patient-reported outcomes (PROs) feedback for patients who self-reported clinically relevant levels of depression or risk behaviors. During the study period (1 January 2006-15 October 2010), 2289 PRO assessments were completed by ... Read more >>

AIDS Behav (AIDS and behavior)
[2017, 21(11):3111-3121]

Cited: 3 times

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Prevalence and Factors Associated with Hazardous Alcohol Use Among Persons Living with HIV Across the US in the Current Era of Antiretroviral Treatment.

Heidi M Crane, Mary E McCaul, Geetanjali Chander, Heidi Hutton, Robin M Nance, Joseph A C Delaney, Joseph O Merrill, Bryan Lau, Kenneth H Mayer, Michael J Mugavero, Matthew Mimiaga, James H Willig, Greer A Burkholder, Daniel R Drozd, Rob J Fredericksen, Karen Cropsey, Richard D Moore, Jane M Simoni, W Christopher Mathews, Joseph J Eron, Sonia Napravnik, Katerina Christopoulos, Elvin Geng, Michael S Saag, Mari M Kitahata,

Hazardous alcohol use is associated with detrimental health outcomes among persons living with HIV (PLWH). We examined the prevalence and factors associated with hazardous alcohol use in the current era using several hazardous drinking definitions and binge drinking defined as ≥5 drinks for men versus ≥4 for women. We included ... Read more >>

AIDS Behav (AIDS and behavior)
[2017, 21(7):1914-1925]

Cited: 20 times

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Cohort profile: seek, test, treat and retain United States criminal justice cohort.

Redonna Chandler, Michael S Gordon, Bridget Kruszka, Lauren N Strand, Frederick L Altice, Curt G Beckwith, Mary L Biggs, William Cunningham, J A Chris Delaney, Patrick M Flynn, Carol E Golin, Kevin Knight, Alex H Kral, Irene Kuo, Jennifer Lorvick, Robin M Nance, Lawrence J Ouellet, Josiah D Rich, Stanley Sacks, David Seal, Anne Spaulding, Sandra A Springer, Faye Taxman, David Wohl, Jeremy D Young, Rebekah Young, Heidi M Crane,

BACKGROUND:The STTR treatment cascade provides a framework for research aimed at improving the delivery of services, care and outcomes of PLWH. The development of effective approaches to increase HIV diagnoses and engage PLWH in subsequent steps of the treatment cascade could lead to earlier and sustained ART treatment resulting in ... Read more >>

Subst Abuse Treat Prev Policy (Substance abuse treatment, prevention, and policy)
[2017, 12(1):24]

Cited: 9 times

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Types of Myocardial Infarction Among Human Immunodeficiency Virus-Infected Individuals in the United States.

Heidi M Crane, Pathmaja Paramsothy, Daniel R Drozd, Robin M Nance, J A Chris Delaney, Susan R Heckbert, Matthew J Budoff, Greer A Burkholder, James H Willig, Michael J Mugavero, William C Mathews, Paul K Crane, Richard D Moore, Joseph J Eron, Sonia Napravnik, Peter W Hunt, Elvin Geng, Priscilla Hsue, Carla Rodriguez, Inga Peter, Greg S Barnes, Justin McReynolds, William B Lober, Kristina Crothers, Matthew J Feinstein, Carl Grunfeld, Michael S Saag, Mari M Kitahata, ,

<h4>Importance</h4>The Second Universal Definition of Myocardial Infarction (MI) divides MIs into different types. Type 1 MIs result spontaneously from instability of atherosclerotic plaque, whereas type 2 MIs occur in the setting of a mismatch between oxygen demand and supply, as with severe hypotension. Type 2 MIs are uncommon in the ... Read more >>

JAMA Cardiol (JAMA cardiology)
[2017, 2(3):260-267]

Cited: 16 times

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Assessing and Refining Myocardial Infarction Risk Estimation Among Patients With Human Immunodeficiency Virus: A Study by the Centers for AIDS Research Network of Integrated Clinical Systems.

Matthew J Feinstein, Robin M Nance, Daniel R Drozd, Hongyan Ning, Joseph A Delaney, Susan R Heckbert, Matthew J Budoff, William C Mathews, Mari M Kitahata, Michael S Saag, Joseph J Eron, Richard D Moore, Chad J Achenbach, Donald M Lloyd-Jones, Heidi M Crane,

<h4>Importance</h4>Persons with human immunodeficiency virus (HIV) that is treated with antiretroviral therapy have improved longevity but face an elevated risk of myocardial infarction (MI) due to common MI risk factors and HIV-specific factors. Despite these elevated MI rates, optimal methods to predict MI risks for HIV-infected persons remain unclear.<h4>Objective</h4>To determine ... Read more >>

JAMA Cardiol (JAMA cardiology)
[2017, 2(2):155-162]

Cited: 31 times

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