Full Text Journal Articles by
Author Robin L Gal

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Racial-Ethnic Inequity in Young Adults with Type 1 Diabetes.

Shivani Agarwal, Lauren G Kanapka, Jennifer K Raymond, Ashby Walker, Andrea Gerard-Gonzalez, Davida Kruger, Maria J Redondo, Michael R Rickels, Viral N Shah, Ashley Butler, Jeffrey Gonzalez, Alandra S Verdejo, Robin L Gal, Steven Willi, Judith A Long,

CONTEXT:Minority young adults (YA) currently represent the largest growing population with type 1 diabetes (T1D) and experience very poor outcomes. Modifiable drivers of disparities need to be identified, but are not well-studied. OBJECTIVE:To describe racial-ethnic disparities among YA with T1D, and identify drivers of glycemic disparity other than socioeconomic status ... Read more >>

J. Clin. Endocrinol. Metab. (The Journal of clinical endocrinology and metabolism)
[2020, :]

Cited: 0 times

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Transforming Performance of Clinical Trials in Pediatric Type 2 Diabetes: A Consortium Model.

Michelle Van Name, Georgeanna Klingensmith, Bryce Nelson, Kupper Wintergerst, Jeffrey Mitchell, Kathryn Norris, William V Tamborlane, ,

Background: Completing phase 3 trials of new drugs for youth with type 2 diabetes is challenging. The Pediatric Diabetes Consortium (PDC) of U.S. pediatric treatment centers developed a Consortium model to improve the efficiency of successfully completing these trials. Aims and Innovations: An aim of the PDC model is to ... Read more >>

Diabetes Technol. Ther. (Diabetes technology & therapeutics)
[2020, 22(4):330-336]

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Eligibility for clinical trials is limited for youth with type 2 diabetes: Insights from the Pediatric Diabetes Consortium T2D Clinic Registry.

William V Tamborlane, Peiyao Chang, Craig Kollman, Georgeanna J Klingensmith, Katrina Ruedy, Robin L Gal, Michelle Van Name, Fida Bacha, Steven Willi, Roy W Beck, ,

BACKGROUND/OBJECTIVE:Restrictive eligibility criteria have hampered enrollment into trials for new drugs for youth with type 2 diabetes (T2D). We utilized Pediatric Diabetes Consortium (PDC) T2D Registry enrollment data to estimate the percentage of patients who would be excluded from current T2D trials based on out-of-range HbA1c levels. We also examined ... Read more >>

Pediatr Diabetes (Pediatric diabetes)
[2018, 19(8):1379-1384]

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Adolescent type 2 diabetes: Comparing the Pediatric Diabetes Consortium and Germany/Austria/Luxemburg Pediatric Diabetes Prospective registries.

Georgeanna J Klingensmith, Stefanie Lanzinger, William V Tamborlane, Sabine E Hofer, Peiyao Cheng, Carine de Beaufort, Robin L Gal, Thomas Reinehr, Craig Kollman, Reinhard W Holl,

OBJECTIVE:To examine and compare the clinical characteristics and treatment of youth with type 2 diabetes (T2D) in two registries: one in Europe and one in the United States. METHODS:Youth with onset of T2D at 10 to 18 years of age with current age <20 years and an office visit after ... Read more >>

Pediatr Diabetes (Pediatric diabetes)
[2018, 19(7):1156-1163]

Cited: 1 time

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Response to Comment on Redondo et al. Racial/Ethnic Minority Youth With Recent-Onset Type 1 Diabetes Have Poor Prognostic Factors. Diabetes Care 2018;41:1017-1024.

Maria Jose Redondo, Ingrid Libman, Peiyao Cheng, Craig Kollman, Mustafa Tosur, Robin L Gal, Fida Bacha, Georgeanna J Klingensmith, Mark Clements, ,

Diabetes Care (Diabetes care)
[2018, 41(7):e125-e126]

Cited: 0 times

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Eating patterns and food intake of persons with type 1 diabetes within the T1D exchange.

Margaret A Powers, Robin L Gal, Crystal G Connor, Meg Mangan, David M Maahs, Mark A Clements, Elizabeth J Mayer-Davis,

To identify dietary intake and eating patterns of people with type 1 diabetes from childhood to later adulthood in relation to HbA1c.Trained interviewers conducted 24-hour recalls via phone utilizing a multiple pass approach and administered two nutrition questionnaires; 463 participants (or parents of participants) within the T1D Exchange clinic registry ... Read more >>

Diabetes Res. Clin. Pract. (Diabetes research and clinical practice)
[2018, 141:217-228]

Cited: 2 times

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Optimal Sampling Duration for Continuous Glucose Monitoring to Determine Long-Term Glycemic Control.

Tonya D Riddlesworth, Roy W Beck, Robin L Gal, Crystal G Connor, Richard M Bergenstal, Sooji Lee, Steven M Willi,

OBJECTIVE:To determine the minimum sample of continuous glucose monitoring (CGM) data needed to accurately reflect 3 months of glycemic control. RESEARCH DESIGN AND METHODS:Three months of CGM data were collected on 257 individuals (age 10-78 years) with type 1 diabetes in two studies (one using the Abbott FreeStyle Libre Pro™ ... Read more >>

Diabetes Technol. Ther. (Diabetes technology & therapeutics)
[2018, 20(4):314-316]

Cited: 10 times

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Racial/Ethnic Minority Youth With Recent-Onset Type 1 Diabetes Have Poor Prognostic Factors.

Maria Jose Redondo, Ingrid Libman, Peiyao Cheng, Craig Kollman, Mustafa Tosur, Robin L Gal, Fida Bacha, Georgeanna J Klingensmith, Mark Clements, ,

To compare races/ethnicities for characteristics, at type 1 diabetes diagnosis and during the first 3 years postdiagnosis, known to influence long-term health outcomes.We analyzed 927 Pediatric Diabetes Consortium (PDC) participants <19 years old (631 non-Hispanic white [NHW], 216 Hispanic, and 80 African American [AA]) diagnosed with type 1 diabetes and ... Read more >>

Diabetes Care (Diabetes care)
[2018, 41(5):1017-1024]

Cited: 8 times

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Racial Differences in the Relationship of Glucose Concentrations and Hemoglobin A1c Levels.

Richard M Bergenstal, Robin L Gal, Roy W Beck,

Ann. Intern. Med. (Annals of internal medicine)
[2018, 168(3):232-233]

Cited: 0 times

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Corneal Endothelial Cell Loss 3 Years After Successful Descemet Stripping Automated Endothelial Keratoplasty in the Cornea Preservation Time Study: A Randomized Clinical Trial.

Jonathan Lass, Beth Ann Benetz, David D Verdier, Loretta B Szczotka-Flynn, Allison R Ayala, Wendi Liang, Anthony J Aldave, Steven P Dunn, Tryone McCall, Shahzad I Mian, Lisa C Navarro, Sanjay V Patel, Sudeep Pramanik, George O Rosenwasser, Kevin W Ross, Mark A Terry, Craig Kollman, Robin L Gal, Roy W Beck, ,

Importance:Demonstrating that endothelial cell loss following Descemet stripping automated endothelial keratoplasty (DSAEK) is independent of donor cornea preservation time (PT) could increase the pool of corneal tissue available for keratoplasty. Objective:To determine whether endothelial cell loss 3 years after successful DSAEK is related to PT. Design, Setting, and Participants:A multicenter, ... Read more >>

JAMA Ophthalmol (JAMA ophthalmology)
[2017, 135(12):1394-1400]

Cited: 11 times

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Effect of Cornea Preservation Time on Success of Descemet Stripping Automated Endothelial Keratoplasty: A Randomized Clinical Trial.

George O Rosenwasser, Loretta B Szczotka-Flynn, Allison R Ayala, Wendi Liang, Anthony J Aldave, Steven P Dunn, Tyrone McCall, Lisa C Navarro, Sudeep Pramanik, Kevin W Ross, R Doyle Stulting, Mark A Terry, Elmer Y Tu, David D Verdier, Craig Kollman, Robin L Gal, Roy W Beck, Jonathan H Lass, ,

Importance:Demonstrating that success of Descemet stripping automated endothelial keratoplasty is similar across donor cornea preservation times (PTs) could increase the donor pool. Objective:To determine whether the 3-year rate of graft success using corneal donor tissue preserved 8 to 14 days is noninferior to that of donor tissue preserved 7 days ... Read more >>

JAMA Ophthalmol (JAMA ophthalmology)
[2017, 135(12):1401-1409]

Cited: 6 times

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Initial Presentation of Type 2 Diabetes in Adolescents Predicts Durability of Successful Treatment with Metformin Monotherapy: Insights from the Pediatric Diabetes Consortium T2D Registry.

Fida Bacha, Peiyao Cheng, Robin L Gal, Craig Kollman, William V Tamborlane, Georgeanna J Klingensmith, Katherine Manseau, Jamie Wood, Roy W Beck, ,

BACKGROUND/AIMS:Many adolescents with type 2 diabetes (T2D) have rapid deterioration of glycemic control on metformin monotherapy within 2 years of diagnosis. METHODS:Enrollment data from the Pediatric Diabetes Consortium T2D Registry were used to categorize 276 youth with a T2D duration ≥2 years into two groups: (1) participants with HbA1c <7.5% ... Read more >>

Horm Res Paediatr (Hormone research in paediatrics)
[2018, 89(1):47-55]

Cited: 3 times

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Racial Differences in the Relationship of Glucose Concentrations and Hemoglobin A1c Levels.

Richard M Bergenstal, Robin L Gal, Crystal G Connor, Rose Gubitosi-Klug, Davida Kruger, Beth A Olson, Steven M Willi, Grazia Aleppo, Ruth S Weinstock, Jamie Wood, Michael Rickels, Linda A DiMeglio, Kathleen E Bethin, Santica Marcovina, Andreana Tassopoulos, Sooji Lee, Elaine Massaro, Suzan Bzdick, Brian Ichihara, Eileen Markmann, Paul McGuigan, Stephanie Woerner, Michelle Ecker, Roy W Beck, ,

Background:Debate exists as to whether the higher hemoglobin A1c (HbA1c) levels observed in black persons than in white persons are due to worse glycemic control or racial differences in the glycation of hemoglobin. Objective:To determine whether a racial difference exists in the relationship of mean glucose and HbA1c. Design:Prospective, 12-week ... Read more >>

Ann. Intern. Med. (Annals of internal medicine)
[2017, 167(2):95-102]

Cited: 36 times

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Predictors of Loss to Follow-Up among Children with Type 2 Diabetes.

Ashley Shoemaker, Peiyao Cheng, Robin L Gal, Craig Kollman, William V Tamborlane, Georgeanna J Klingensmith, Mark A Clements, Tamara S Hannon, Rubina Heptulla, Joane Less, Jamie Wood, ,

Youth with type 2 diabetes (T2D) have poor compliance with medical care. This study aimed to determine which demographic and clinical factors differ between youth with T2D who receive care in a pediatric diabetes center versus youth lost to follow-up for >18 months.Data were analyzed from 496 subjects in the ... Read more >>

Horm Res Paediatr (Hormone research in paediatrics)
[2017, 87(6):377-384]

Cited: 2 times

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Clinical outcomes in youth beyond the first year of type 1 diabetes: Results of the Pediatric Diabetes Consortium (PDC) type 1 diabetes new onset (NeOn) study.

Eda Cengiz, Peiyao Cheng, Katrina J Ruedy, Craig Kollman, William V Tamborlane, Georgeanna J Klingensmith, Robin L Gal, Janet Silverstein, Joyce Lee, Maria J Redondo, Roy W Beck, ,

OBJECTIVE:Current data are limited on the course of type 1 diabetes (T1D) in children and adolescents through the first few years of diabetes. The Pediatric Diabetes Consortium T1D new onset (NeOn) Study was undertaken to prospectively assess natural history and clinical outcomes in children treated at 7 US diabetes centers ... Read more >>

Pediatr Diabetes (Pediatric diabetes)
[2017, 18(7):566-573]

Cited: 3 times

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Corticosteroids for treating optic neuritis.

Robin L Gal, Satyanarayana S Vedula, Roy Beck,

BACKGROUND:Optic neuritis is an inflammatory disease of the optic nerve. It usually presents with an abrupt loss of vision and recovery of vision is almost never complete. It occurs more commonly in women than in men. Closely linked in pathogenesis, optic neuritis may be the initial manifestation for multiple sclerosis. ... Read more >>

Cochrane Database Syst Rev (The Cochrane database of systematic reviews)
[2015, (8):CD001430]

Cited: 8 times

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Cornea preservation time study: methods and potential impact on the cornea donor pool in the United States.

Jonathan H Lass, Loretta B Szczotka-Flynn, Allison R Ayala, Beth A Benetz, Robin L Gal, Anthony J Aldave, Michelle M Corrigan, Steven P Dunn, Ty L McCall, Sudeep Pramanik, George O Rosenwasser, Kevin W Ross, Mark A Terry, David D Verdier, ,

The aim of this study was to describe the aims, methods, donor and recipient cohort characteristics, and potential impact of the Cornea Preservation Time Study (CPTS).The CPTS is a randomized clinical trial conducted at 40 clinical sites (70 surgeons) designed to assess the effect of donor cornea preservation time (PT) ... Read more >>

Cornea (Cornea)
[2015, 34(6):601-608]

Cited: 16 times

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Factors associated with corneal graft survival in the cornea donor study.

, Alan Sugar, Robin L Gal, Craig Kollman, Dan Raghinaru, Mariya Dontchev, Christopher R Croasdale, Robert S Feder, Edward J Holland, Jonathan H Lass, Jonathan I Macy, Mark J Mannis, Patricia W Smith, Sarkis H Soukiasian, Roy W Beck,

The Cornea Donor Study (CDS) showed that donor age is not a factor in survival of most penetrating keratoplasties for endothelial disease. Secondary analyses confirm the importance of surgical indication and presence of glaucoma in outcomes at 10 years.To assess the relationship between donor and recipient factors and corneal graft ... Read more >>

JAMA Ophthalmol (JAMA ophthalmology)
[2015, 133(3):246-254]

Cited: 27 times

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The effect of donor diabetes history on graft failure and endothelial cell density 10 years after penetrating keratoplasty.

Jonathan H Lass, Tonya D Riddlesworth, Robin L Gal, Craig Kollman, Beth A Benetz, Francis W Price, Alan Sugar, Mark A Terry, Mark Soper, Roy W Beck, ,

To examine the long-term effect of donor diabetes history on graft failure and endothelial cell density (ECD) after penetrating keratoplasty (PK) in the Cornea Donor Study.Multicenter, prospective, double-masked, controlled clinical trial.One thousand ninety subjects undergoing PK for a moderate risk condition, principally Fuchs' dystrophy or pseudophakic or aphakic corneal edema, ... Read more >>

Ophthalmology (Ophthalmology)
[2015, 122(3):448-456]

Cited: 13 times

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A mathematical model to predict endothelial cell density following penetrating keratoplasty with selective dropout from graft failure.

Tonya D Riddlesworth, Craig Kollman, Jonathan H Lass, Sanjay V Patel, R Doyle Stulting, Beth Ann Benetz, Robin L Gal, Roy W Beck,

We constructed several mathematical models that predict endothelial cell density (ECD) for patients after penetrating keratoplasty (PK) for a moderate-risk condition (principally Fuchs' dystrophy or pseudophakic/aphakic corneal edema).In a subset (n = 591) of Cornea Donor Study participants, postoperative ECD was determined by a central reading center. Various statistical models ... Read more >>

Invest. Ophthalmol. Vis. Sci. (Investigative ophthalmology & visual science)
[2014, 55(12):8409-8415]

Cited: 5 times

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Corneal graft rejection 10 years after penetrating keratoplasty in the cornea donor study.

Steven P Dunn, Robin L Gal, Craig Kollman, Dan Raghinaru, Mariya Dontchev, Christopher L Blanton, Edward J Holland, Jonathan H Lass, Kenneth R Kenyon, Mark J Mannis, Shahzad I Mian, Christopher J Rapuano, Walter J Stark, Roy W Beck, ,

The aim of this study was to assess the effect of donor and recipient factors on corneal allograft rejection and evaluate whether a rejection event was associated with graft failure.One thousand ninety subjects undergoing penetrating keratoplasty for a moderate risk condition (principally Fuchs dystrophy or pseudophakic corneal edema) were followed ... Read more >>

Cornea (Cornea)
[2014, 33(10):1003-1009]

Cited: 13 times

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Donor age and factors related to endothelial cell loss 10 years after penetrating keratoplasty: Specular Microscopy Ancillary Study.

, Jonathan H Lass, Beth Ann Benetz, Robin L Gal, Craig Kollman, Dan Raghinaru, Mariya Dontchev, Mark J Mannis, Edward J Holland, Christopher Chow, Kristen McCoy, Francis W Price, Alan Sugar, David D Verdier, Roy W Beck,

To examine the effect of donor age and other perioperative factors on long-term endothelial cell loss after penetrating keratoplasty (PKP).Multicenter, prospective, double-masked clinical trial.We included 176 participants from the Cornea Donor Study cohort who had not experienced graft failure ≥ 10 years after PKP for a moderate risk condition (principally ... Read more >>

Ophthalmology (Ophthalmology)
[2013, 120(12):2428-2435]

Cited: 29 times

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The effect of donor age on penetrating keratoplasty for endothelial disease: graft survival after 10 years in the Cornea Donor Study.

, Mark J Mannis, Edward J Holland, Robin L Gal, Mariya Dontchev, Craig Kollman, Dan Raghinaru, Steven P Dunn, Robert L Schultze, David D Verdier, Jonathan H Lass, Irving M Raber, Joel Sugar, Mark S Gorovoy, Alan Sugar, R Doyle Stulting, Monty M Montoya, Jeffrey G Penta, Beth Ann Benetz, Roy W Beck,

To determine whether the 10-year success rate of penetrating keratoplasty for corneal endothelial disorders is associated with donor age.Multicenter, prospective, double-masked clinical trial.A total of 1090 participants undergoing penetrating keratoplasty at 80 sites for Fuchs' dystrophy (62%), pseudophakic/aphakic corneal edema (34%), or another corneal endothelial disorder (4%) and followed for ... Read more >>

Ophthalmology (Ophthalmology)
[2013, 120(12):2419-2427]

Cited: 24 times

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Corneal thickness as a predictor of corneal transplant outcome.

David D Verdier, Alan Sugar, Keith Baratz, Roy Beck, Mariya Dontchev, Steven Dunn, Robin L Gal, Edward J Holland, Craig Kollman, Jonathan H Lass, Mark J Mannis, Jeffrey Penta, ,

To assess corneal thickness (CT) and correlation with graft outcome after penetrating keratoplasty in the Cornea Donor Study.A total of 887 subjects with a corneal transplant for a moderate-risk condition (principally Fuchs dystrophy or pseudophakic corneal edema) had postoperative CT measurements throughout a 5-year follow-up time. Relationships between baseline (recipient, ... Read more >>

Cornea (Cornea)
[2013, 32(6):729-736]

Cited: 9 times

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Endothelial morphometric measures to predict endothelial graft failure after penetrating keratoplasty.

Beth Ann Benetz, Jonathan H Lass, Robin L Gal, Alan Sugar, Harry Menegay, Mariya Dontchev, Craig Kollman, Roy W Beck, Mark J Mannis, Edward J Holland, Mark Gorovoy, Sadeer B Hannush, John E Bokosky, James W Caudill, ,

Endothelial morphometric measures have potential value in predicting graft failure after penetrating keratoplasty.To determine whether preoperative and/or postoperative central morphometric measures (endothelial cell density [ECD], coefficient of variation [CV], and percentage of hexagonality [HEX]) and their postoperative changes are predictive of graft failure caused by endothelial decompensation after penetrating keratoplasty ... Read more >>

JAMA Ophthalmol (JAMA ophthalmology)
[2013, 131(5):601-608]

Cited: 13 times

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