Full Text Journal Articles by
Author Robert Spencer

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Enhanced trace element mobilization by Earth's ice sheets.

Jon R Hawkings, Mark L Skidmore, Jemma L Wadham, John C Priscu, Peter L Morton, Jade E Hatton, Christopher B Gardner, Tyler J Kohler, Marek Stibal, Elizabeth A Bagshaw, August Steigmeyer, Joel Barker, John E Dore, W Berry Lyons, Martyn Tranter, Robert G M Spencer, ,

Trace elements sustain biological productivity, yet the significance of trace element mobilization and export in subglacial runoff from ice sheets is poorly constrained at present. Here, we present size-fractionated (0.02, 0.22, and 0.45 µm) concentrations of trace elements in subglacial waters from the Greenland Ice Sheet (GrIS) and the Antarctic ... Read more >>

Proc Natl Acad Sci U S A (Proceedings of the National Academy of Sciences of the United States of America)
[2020, :]

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Increased intracranial pressure in the setting of Multisystem Inflammatory Syndrome in Children, associated with COVID-19

Alyssa Baccarella, Alexandra Linder, Robert Spencer, Alexander Jonokuchi, Paul Benjamin King, Angel Maldonado-Soto, Alexis Boneparth, Benjamin S. Hooe, Adam J. Schweickert, Rebecca Carlin, Francesca Kingery, Wendy S. Vargas, Taylor B. Sewell, Wendy G. Silver,

Pediatr Neurol (Pediatric neurology)
[2020, :]

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Deciphering Dissolved Organic Matter: Ionization, Dopant, and Fragmentation Insights via Fourier Transform-Ion Cyclotron Resonance Mass Spectrometry.

Martin R Kurek, Brett A Poulin, Amy M McKenna, Robert G M Spencer,

Fourier transform-ion cyclotron resonance mass spectrometry (FT-ICR MS) has been increasingly employed to characterize dissolved organic matter (DOM) across a range of aquatic environments highlighting the role of DOM in global carbon cycling. DOM analysis commonly utilizes electrospray ionization (ESI), while some have implemented other techniques, including dopant-assisted atmospheric pressure ... Read more >>

Environ Sci Technol (Environmental science & technology)
[2020, :]

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Rainstorm events shift the molecular composition and export of dissolved organic matter in a large drinking water reservoir in China: High frequency buoys and field observations.

Yongqiang Zhou, Miao Liu, Lei Zhou, Kyoung-Soon Jang, Hai Xu, Kun Shi, Guangwei Zhu, Mingliang Liu, Jianming Deng, Yunlin Zhang, Robert G M Spencer, Dolly N Kothawala, Erik Jeppesen, Fengchang Wu,

Rainstorm events can flush large amounts of terrestrial organic-rich material into lakes that are used for drinking water. To date, few studies have been carried out to investigate how rainstorm events change the molecular composition, bio-lability, and flux of upstream-imported dissolved organic matter (DOM), which can impact the odor and ... Read more >>

Water Res (Water research)
[2020, 187:116471]

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Climatic, land cover, and anthropogenic controls on dissolved organic matter quantity and quality from major alpine rivers across the Himalayan-Tibetan Plateau.

Meilian Chen, Chaoliu Li, Robert G M Spencer, Nagamitsu Maie, Jin Hur, Amy M McKenna, Fangping Yan,

Alpine rivers in mountainous regions are crucial not only for land-ocean transfer of chemical species and sediments, but also for water, food, and energy security. Here, we examined dissolved organic matter (DOM) from the major alpine waters on the Tibetan Plateau. Our results revealed a decreasing trend of DOM quantity ... Read more >>

Sci Total Environ (The Science of the total environment)
[2021, 754:142411]

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Hydrocarbons to carboxyl-rich alicyclic molecules: A continuum model to describe biodegradation of petroleum-derived dissolved organic matter in contaminated groundwater plumes.

David C Podgorski, Phoebe Zito, Anne M Kellerman, Barbara A Bekins, Isabelle M Cozzarelli, Donald F Smith, Xiaoyan Cao, Klaus Schmidt-Rohr, Sasha Wagner, Aron Stubbins, Robert G M Spencer,

Relationships between dissolved organic matter (DOM) reactivity and chemical composition in a groundwater plume containing petroleum-derived DOM (DOM<sub>HC</sub>) were examined by quantitative and qualitative measurements to determine the source and chemical composition of the compounds that persist downgradient. Samples were collected from a transect down the core of the plume ... Read more >>

J Hazard Mater (Journal of hazardous materials)
[2021, 402:123998]

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COVID-19 and the young heart: what are we missing?

Robert Spencer, Nak Hyun Choi, Keriann Potter, Sanghee Suh, Michael Fremed,

World J Pediatr (World journal of pediatrics : WJP)
[2020, 16(6):553-555]

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COVID-19 Inflammatory Syndrome With Clinical Features Resembling Kawasaki Disease.

Robert Spencer, Ryan C Closson, Mark Gorelik, Alexis D Boneparth, Rebecca F Hough, Karen P Acker, Usha Krishnan,

We describe 2 patients with coronavirus disease who had multiple clinical features suggestive of Kawasaki disease (KD). Both patients presented with fever lasting >5 days and were found to have rash, conjunctival injection, and swollen lips. One patient also had extremity swelling, whereas the other developed desquamation of the fingers. ... Read more >>

Pediatrics (Pediatrics)
[2020, 146(3):]

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Arrhythmia in the Amazon: La Niña influence on riverine organic molecular signatures

Martin Kurek, Aron Stubbins, Travis Drake, Jose Mauro Moura, Robert Holmes, Helena Osterholz, Thorsten Dittmar, Bernhard Peucker-Ehrenbrink, Miyuki Mitsuya, Robert Spencer,

Abstract As climate-driven El Niño Southern Oscillation (ENSO) events are projected to increase in frequency and severity, much attention has focused on impacts regarding ecosystem productivity and carbon balance in Amazonian rainforests, with little attention given to carbon dynamics in fluvial ecosystems. We compared the wet 2012 La Niña period ... Read more >>

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Reflections on Bruce S. McEwen's contributions to stress neurobiology and so much more.

Firdaus S Dhabhar, Michael J Meaney, Robert M Sapolsky, Robert L Spencer,

The authors highlight, from a firsthand perspective, Bruce S. McEwen's seminal influence on the field of stress neurobiology and beyond, and how these investigations have yielded important insights, principles and critical questions that continue to guide stress research today. Featured are discussion of: 1) the important inverted-U relationship between stress/glucocorticoids ... Read more >>

Stress (Stress (Amsterdam, Netherlands))
[2020, 23(5):499-508]

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Chronic Thromboembolic Pulmonary Hypertension in a Child With Sickle Cell Disease.

Robert Spencer, Gerson Valencia Villeda, Koji Takeda, Erika B Rosenzweig,

Chronic thromboembolic pulmonary hypertension is a potentially curable form of pre-capillary pulmonary hypertension (PH) resulting from incomplete resolution of pulmonary thromboemboli. We describe an 11-year-old boy with homozygous sickle cell disease with an indwelling catheter found to have severe PH on routine screening echocardiography. The diagnosis was confirmed by CT, ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:363]

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Memory and the circadian system: Identifying candidate mechanisms by which local clocks in the brain may regulate synaptic plasticity.

Matthew J Hartsock, Robert L Spencer,

The circadian system is an endogenous biological network responsible for coordinating near-24-h cycles in behavior and physiology with daily timing cues from the external environment. In this review, we explore how the circadian system regulates memory formation, retention, and recall. Circadian rhythms in these memory processes may arise through several ... Read more >>

Neurosci Biobehav Rev (Neuroscience and biobehavioral reviews)
[2020, 118:134-162]

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Developing learning slope scores for the repeatable battery for the assessment of neuropsychological status.

Robert J Spencer, Brian D Gradwohl, Trevor F Williams, Victoria M Kordovski, Dustin B Hammers,

Initial learning and learning slope are often acknowledged as important qualitative aspects of learning, but the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) contains discrete indices for neither. The traditional method of calculating learning slope involves a difference score between the last trial and first trial, which is ... Read more >>

Appl Neuropsychol Adult (Applied neuropsychology. Adult)
[2020, :1-7]

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Clinically Meaningful Change in Itch Intensity Scores: an Evaluation in Patients with Chronic Kidney Disease-associated Pruritus.

Margaret Vernon, Sonja Ständer, Catherine Munera, Robert H Spencer, Frédérique Menzaghi,

J Am Acad Dermatol (Journal of the American Academy of Dermatology)
[2020, :]

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Performing an urgent neonatal cardiac intervention safely during the COVID-19 pandemic.

Robert Spencer, Diana Vargas Chaves, Maria Cristina Brooks, Nimrod Goldshtrom, Leslie Moroz, Russel Miller, Julie Glickstein, Stéphanie Levasseur, Emile A Bacha, Mariel E Turner, Kanwal M Farooqi,

The current pandemic has driven the medical community to adapt quickly to unprecedented challenges. Among these challenges is the need to minimize staff exposure to COVID-19 during neonatal cardiac procedures. In this report, we describe measures we have taken to protect health care workers while ensuring successful outcomes. These measures ... Read more >>

Prog Pediatr Cardiol (Progress in pediatric cardiology)
[2020, :101265]

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The Analysis of Teaching of Medical Schools (AToMS) survey: an analysis of 47,258 timetabled teaching events in 25 UK medical schools relating to timing, duration, teaching formats, teaching content, and problem-based learning.

Oliver Patrick Devine, Andrew Christopher Harborne, Hugo Layard Horsfall, Tobin Joseph, Tess Marshall-Andon, Ryan Samuels, Joshua William Kearsley, Nadine Abbas, Hassan Baig, Joseph Beecham, Natasha Benons, Charlie Caird, Ryan Clark, Thomas Cope, James Coultas, Luke Debenham, Sarah Douglas, Jack Eldridge, Thomas Hughes-Gooding, Agnieszka Jakubowska, Oliver Jones, Eve Lancaster, Calum MacMillan, Ross McAllister, Wassim Merzougui, Ben Phillips, Simon Phillips, Omar Risk, Adam Sage, Aisha Sooltangos, Robert Spencer, Roxanne Tajbakhsh, Oluseyi Adesalu, Ivan Aganin, Ammar Ahmed, Katherine Aiken, Alimatu-Sadia Akeredolu, Ibrahim Alam, Aamna Ali, Richard Anderson, Jia Jun Ang, Fady Sameh Anis, Sonam Aojula, Catherine Arthur, Alena Ashby, Ahmed Ashraf, Emma Aspinall, Mark Awad, Abdul-Muiz Azri Yahaya, Shreya Badhrinarayanan, Soham Bandyopadhyay, Sam Barnes, Daisy Bassey-Duke, Charlotte Boreham, Rebecca Braine, Joseph Brandreth, Zoe Carrington, Zoe Cashin, Shaunak Chatterjee, Mehar Chawla, Chung Shen Chean, Chris Clements, Richard Clough, Jessica Coulthurst, Liam Curry, Vinnie Christine Daniels, Simon Davies, Rebecca Davis, Hanelie De Waal, Nasreen Desai, Hannah Douglas, James Druce, Lady-Namera Ejamike, Meron Esere, Alex Eyre, Ibrahim Talal Fazmin, Sophia Fitzgerald-Smith, Verity Ford, Sarah Freeston, Katherine Garnett, Whitney General, Helen Gilbert, Zein Gowie, Ciaran Grafton-Clarke, Keshni Gudka, Leher Gumber, Rishi Gupta, Chris Harlow, Amy Harrington, Adele Heaney, Wing Hang Serene Ho, Lucy Holloway, Christina Hood, Eleanor Houghton, Saba Houshangi, Emma Howard, Benjamin Human, Harriet Hunter, Ifrah Hussain, Sami Hussain, Richard Thomas Jackson-Taylor, Bronwen Jacob-Ramsdale, Ryan Janjuha, Saleh Jawad, Muzzamil Jelani, David Johnston, Mike Jones, Sadhana Kalidindi, Savraj Kalsi, Asanish Kalyanasundaram, Anna Kane, Sahaj Kaur, Othman Khaled Al-Othman, Qaisar Khan, Sajan Khullar, Priscilla Kirkland, Hannah Lawrence-Smith, Charlotte Leeson, Julius Elisabeth Richard Lenaerts, Kerry Long, Simon Lubbock, Jamie Mac Donald Burrell, Rachel Maguire, Praveen Mahendran, Saad Majeed, Prabhjot Singh Malhotra, Vinay Mandagere, Angelos Mantelakis, Sophie McGovern, Anjola Mosuro, Adam Moxley, Sophie Mustoe, Sam Myers, Kiran Nadeem, Reza Nasseri, Tom Newman, Richard Nzewi, Rosalie Ogborne, Joyce Omatseye, Sophie Paddock, James Parkin, Mohit Patel, Sohini Pawar, Stuart Pearce, Samuel Penrice, Julian Purdy, Raisa Ramjan, Ratan Randhawa, Usman Rasul, Elliot Raymond-Taggert, Rebecca Razey, Carmel Razzaghi, Eimear Reel, Elliot John Revell, Joanna Rigbye, Oloruntobi Rotimi, Abdelrahman Said, Emma Sanders, Pranoy Sangal, Nora Sangvik Grandal, Aadam Shah, Rahul Atul Shah, Oliver Shotton, Daniel Sims, Katie Smart, Martha Amy Smith, Nick Smith, Aninditya Salma Sopian, Matthew South, Jessica Speller, Tom J Syer, Ngan Hong Ta, Daniel Tadross, Benjamin Thompson, Jess Trevett, Matthew Tyler, Roshan Ullah, Mrudula Utukuri, Shree Vadera, Harriet Van Den Tooren, Sara Venturini, Aradhya Vijayakumar, Melanie Vine, Zoe Wellbelove, Liora Wittner, Geoffrey Hong Kiat Yong, Farris Ziyada, I C McManus,

BACKGROUND:What subjects UK medical schools teach, what ways they teach subjects, and how much they teach those subjects is unclear. Whether teaching differences matter is a separate, important question. This study provides a detailed picture of timetabled undergraduate teaching activity at 25 UK medical schools, particularly in relation to problem-based ... Read more >>

BMC Med (BMC medicine)
[2020, 18(1):126]

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The Montreal Cognitive Assessment in Veteran Postacute Care: Implications of Cut Scores.

Kathryn Tolle, Valencia Montgomery, Brian Gradwohl, Robert Spencer, Julija Stelmokas,

BACKGROUND:The Montreal Cognitive Assessment (MoCA) is often used for cognitive screening across health care settings, especially in rehabilitation centers, where assessment and treatment of cognitive function is considered key for successful multidisciplinary treatment. Although the original MoCA validation study suggested a cut score of <26 to identify cognitive impairment, recent ... Read more >>

Cogn Behav Neurol (Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology)
[2020, 33(2):129-136]

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Validation and extension of personality disorder spectra scales from MMPI-2-RF items.

Andrew C Hale, Sharon M Nelson, Jaclyn Reckow, Robert J Spencer,

OBJECTIVES:Recent efforts have been made to develop 10 personality disorder spectra scales using items from the Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF). These scales, developed by Sellbom et al. (2018, J. Pers. Assess., 1-15), demonstrated good validity and warranted cross-validation. METHOD:In all, 97 veterans undergoing neuropsychological evaluation in a ... Read more >>

J Clin Psychol (Journal of clinical psychology)
[2020, 76(9):1754-1774]

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Correction to "Molecular-Level Composition and Acute Toxicity of Photosolubilized Petrogenic Carbon".

Phoebe Zito, David C Podgorski, Joshua Johnson, Huan Chen, Ryan P Rodgers, François Guillemette, Anne M Kellerman, Robert G M Spencer, Matthew A Tarr,

Environ Sci Technol (Environmental science & technology)
[2020, 54(9):5922]

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Examining the Relationship between a Verbal Incidental Learning Measure from the WAIS-IV and Neuroimaging Biomarkers for Alzheimer's Pathology.

Dustin B Hammers, Amanda Kucera, Robert J Spencer, Tracy J Abildskov, Zane G Archibald, John M Hoffman, Elizabeth A Wilde,

Convergent validation of a verbal incidental learning (IL) task from the WAIS-IV using neuroimaging biomarkers is warranted to understand its sensitivity to Alzheimer's disease (AD) pathology. Fifty-five memory clinic patients aged 59 to 87 years received neuropsychological assessment, and measures of IL and quantitative brain imaging. Worse IL-Total Score and IL-Similarities ... Read more >>

Dev Neuropsychol (Developmental neuropsychology)
[2020, 45(3):95-109]

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Mercury Export from Arctic Great Rivers.

Scott Zolkos, David P Krabbenhoft, Anya Suslova, Suzanne E Tank, James W McClelland, Robert G M Spencer, Alexander Shiklomanov, Alexander V Zhulidov, Tatiana Gurtovaya, Nikita Zimov, Sergey Zimov, Edda A Mutter, Les Kutny, Edwin Amos, Robert M Holmes,

Land-ocean linkages are strong across the circumpolar north, where the Arctic Ocean accounts for 1% of the global ocean volume and receives more than 10% of the global river discharge. Yet estimates of Arctic riverine mercury (Hg) export constrained from direct Hg measurements remain sparse. Here, we report results from ... Read more >>

Environ Sci Technol (Environmental science & technology)
[2020, 54(7):4140-4148]

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The Prevalence and Incidence of Attention-deficit/Hyperactivity Disorder in the Veterans Health Administration From 2009 to 2016.

Andrew C Hale, Kipling M Bohnert, Robert J Spencer, Dara Ganoczy, Paul N Pfeiffer,

BACKGROUND:The prevalence and incidence of attention-deficit/hyperactivity disorder (ADHD) have increased substantially among children and adolescents over the past decade; however, little is known regarding trends in adult populations. OBJECTIVE:The objective of this study was to explore trends in the prevalence, incidence, and correlates of adult ADHD in a national sample ... Read more >>

Med Care (Medical care)
[2020, 58(3):273-279]

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Land‐use controls on carbon biogeochemistry in lowland streams of the Congo Basin

Travis W Drake, David C Podgorski, Bienvenu Dinga, Jeffrey P Chanton, Johan Six, Robert G M Spencer,

The flux and composition of carbon (C) from land to rivers represents a critical component of the global C cycle as well as a powerful integrator of landscape‐level processes. In the Congo Basin, an expansive network of streams and rivers transport and cycle terrigenous C sourced from the largest swathe ... Read more >>

(Global change biology.)
[2020, 26(3):1374-1389]

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Intrathecal Baclofen for Severe Spasticity: Longitudinal Data From the Product Surveillance Registry.

Mya Caryn Schiess, Sam Eldabe, Peter Konrad, Lisa Molus, Robert Spencer, Katherine Stromberg, Todd Weaver, Robert Plunkett,

OBJECTIVE:To assist in the assessment of intrathecal baclofen (ITB) therapy risks and benefits by providing surgical intervention rate, safety, and elective device replacement rate data. MATERIALS AND METHODS:An ongoing prospective, long-term, multicenter Product Surveillance Registry (PSR) (NCT01524276) enrolled consented patients implanted with the SynchroMed II infusion system. Pump and catheter ... Read more >>

Neuromodulation (Neuromodulation : journal of the International Neuromodulation Society)
[2020, :]

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Randomized Controlled Trial of Difelikefalin for Chronic Pruritus in Hemodialysis Patients.

Steven Fishbane, Vandana Mathur, Michael J Germain, Shayan Shirazian, Sarbani Bhaduri, Catherine Munera, Robert H Spencer, Frédérique Menzaghi, ,

Introduction:There is an unmet medical need for pruritus associated with chronic kidney disease, a distressing complication characterized by generalized and persistent itch affecting 20% to 40% of patients undergoing hemodialysis. Here we report the results of a phase 2 trial evaluating the efficacy and safety of a novel peripherally restricted ... Read more >>

Kidney Int Rep (Kidney international reports)
[2020, 5(5):600-610]

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