Full Text Journal Articles by
Author Robert Parker

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Necrotizing Fasciitis: A Predictable Burden in Rural Kenya.

Joyce Lunar, Sinkeet S Ranketi, Beverly Owino, Mark Oloo, Robert K Parker,

BACKGROUND:Necrotizing fasciitis (NF) is a devastating disease with substantial morbidity and mortality. Poor outcomes are attributed to delayed diagnosis and management. Tenwek Hospital, a teaching and referral center in rural Kenya, manages many cases despite variable resources. We aimed to understand the burden of NF. METHODS:All patients with admission NF ... Read more >>

World J Surg (World journal of surgery)
[2020, :]

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A retrospective cohort study of endoscopic therapy and esophagectomy for stage 1 esophageal cancer: less is more.

Justin C McCarty, Robert K Parker, Roberto J Vidri, Kortney A Robinson, Stuart Lipsitz, Sidhu P Gangadharan, Prasad G Iyer,

Current guidelines recommend consideration of endoscopic therapy (ET) when treating select stage I esophageal cancers. The proportion of esophageal cancers treated with ET compared with esophagectomy has increased over time. Overall and cancer-specific survival have not been shown to be superior with ET in prior population-based studies. We thus evaluated ... Read more >>

Gastrointest. Endosc. (Gastrointestinal endoscopy)
[2020, :]

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Service Use Classes Among School-aged Children From the Autism Treatment Network Registry.

Olivia J Lindly, James Chan, Susan E Levy, Robert A Parker, Karen A Kuhlthau,

Use of specific services may help to optimize health for children with autism spectrum disorder (ASD); however, little is known about their service use patterns. We aimed to (1) define service use groups and (2) determine associations of sociodemographic, developmental, behavioral, and health characteristics with service use groups among school-aged ... Read more >>

Pediatrics (Pediatrics)
[2020, 145(Suppl 1):S140-S150]

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Higher Acuity Resource Utilization With Older Age and Poorer HIV Control in Adolescents and Young Adults in the HIV Research Network.

Anne M Neilan, Frances Lu, Kelly A Gebo, Rebeca Diaz-Reyes, Mingshu Huang, Robert A Parker, Brad Karalius, Kunjal Patel, Cindy Voss, Andrea L Ciaranello, Allison L Agwu,

BACKGROUND:Adolescents and young adults (AYA) with HIV experience poorer health outcomes compared with adults. To improve care for AYA with HIV, information about patterns of costly health care resource utilization is needed. METHODS:Among 13-30 year olds in the US HIV Research Network, we stratified outpatient visits, emergency department (ED) visits, ... Read more >>

J. Acquir. Immune Defic. Syndr. (Journal of acquired immune deficiency syndromes (1999))
[2020, 83(4):424-433]

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Families' Experiences With Family Navigation Services in the Autism Treatment Network.

Morgan K Crossman, Olivia J Lindly, James Chan, Megan Eaves, Karen A Kuhlthau, Robert A Parker, Daniel L Coury, Debra H Zand, Lisa A Nowinski, Kathryn Smith, Megan Tomkinson, Donna S Murray,

Families of children with autism spectrum disorder (ASD) often experience challenges navigating multiple systems to access services. Family navigation (FN) is a model to provide information and support to access appropriate services. Few studies have been used to examine FN's effectiveness for families of children with ASD. This study used ... Read more >>

Pediatrics (Pediatrics)
[2020, 145(Suppl 1):S60-S71]

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Surgical Training Throughout Africa: A Review of Operative Case Volumes at Multiple Training Centers.

Robert K Parker, Hillary M Topazian, Wairimu Ndegwa, Patricia Chesang, Shinji Strain, Keir Thelander, Andrea S Parker, Robert Riviello,

BACKGROUND:Adequate surgical training is paramount to produce competent surgeons to address the global burden of surgical disease. The Pan-African Academy of Christian Surgeons (PAACS) has general surgery training programs in eight countries. Operative case volumes have been positively associated with improved trainee performance and patient outcomes. For certification in the ... Read more >>

World J Surg (World journal of surgery)
[2020, :]

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Neural correlates of working memory function in pediatric cancer survivors treated with chemotherapy: an fMRI study.

Patricia Stefancin, Christine Cahaney, Robert I Parker, Thomas Preston, Kelly Coulehan, Laura Hogan, Timothy Q Duong,

The goal of this study is to investigate the neural correlates of working memory function associated with chemotherapy in pediatric cancer survivors using event-related functional MRI (fMRI) analysis. Fifteen pediatric cancer survivors treated with chemotherapy and 15 healthy controls were studied. Blood oxygenation level dependent (BOLD) fMRI was acquired. A ... Read more >>

NMR Biomed (NMR in biomedicine)
[2020, 33(6):e4296]

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Effectiveness of the Extension for Community Health Outcomes Model as Applied to Primary Care for Autism: A Partial Stepped-Wedge Randomized Clinical Trial.

Micah O Mazurek, Robert A Parker, James Chan, Karen Kuhlthau, Kristin Sohl, ,

Importance:The Extension for Community Health Outcomes (ECHO) model is a widely adopted technology-based model for training primary care physicians and practitioners (PCPs) to care for patients with complex conditions. Despite its popularity, to our knowledge, direct effects of ECHO on clinical practice have not been tested in a large-scale study. ... Read more >>

JAMA Pediatr (JAMA pediatrics)
[2020, :e196306]

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Primary Care Providers' Perceived Barriers and Needs for Support in Caring for Children with Autism.

Micah O Mazurek, Christina Harkins, Michelle Menezes, James Chan, Robert A Parker, Karen Kuhlthau, Kristin Sohl,

A mixed methods approach was used to examine perspectives of 114 primary care providers regarding barriers and needs for support in caring for children with autism. The most common barriers related to lack of knowledge and resources for diagnosing and treating children with autism, and inadequate visit time and reimbursement. ... Read more >>

J. Pediatr. (The Journal of pediatrics)
[2020, 221:240-245.e1]

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The whole blood phagocytosis assay: a clinically relevant test of neutrophil function and dysfunction in community-acquired pneumonia

Jesús Reiné, Jamie Rylance, Daniela Ferreira, Shaun Pennington, Ingeborg Dorothea Welters, Robert Parker, Ben Morton,

Abstract OBJECTIVE: To refine and validate a neutrophil function assay with clinical relevance for patients with community-acquired pneumonia (CAP). Design: Two phase cross-sectional study to standardise and refine the assay in blood from healthy volunteers and test neutrophil phagocytic function in hospital patients with CAP. Participants : Phase one: Healthy ... Read more >>

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Low Neuroactive Steroids Identifies a Biological Subtype of Depression in Adults with Human Immunodeficiency Virus on Suppressive Antiretroviral Therapy.

Shibani S Mukerji, Vikas Misra, David R Lorenz, Sukrutha Chettimada, Kiana Keller, Scott Letendre, Ronald J Ellis, Susan Morgello, Robert A Parker, Dana Gabuzda,

BACKGROUND:The prevalence and mortality risk of depression in people with Human Immunodeficiency Virus (HIV)-infection (PWH) on antiretroviral therapy (ART) is higher than in the general population, yet biomarkers for therapeutic targeting are unknown. Here, we aimed to identify plasma metabolites associated with depressive symptoms in PWH on ART. METHODS:This is ... Read more >>

J. Infect. Dis. (The Journal of infectious diseases)
[2020, :]

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Access to Dental Visits and Correlates of Preventive Dental Care in Children with Autism Spectrum Disorder.

Rachel M Fenning, Robin Steinberg-Epstein, Eric M Butter, James Chan, Kelly McKinnon-Bermingham, Kimberly J Hammersmith, Jacquelyn Moffitt, Amy M Shui, Robert A Parker, Daniel L Coury, Paul P Wang, Karen A Kuhlthau,

Dental care received by children in the Autism Speaks Autism Treatment Network (ATN) was compared to National Survey of Children's Health (NSCH) data for children without special healthcare needs and children with parent-reported ASD. Correlates of obtained preventive dental services were examined within the ATN sample. Participants included 375 families ... Read more >>

J Autism Dev Disord (Journal of autism and developmental disorders)
[2020, :]

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Accelerating availability of clinically-relevant parameter estimates from thromboelastogram point-of-care device.

Michelle A Pressly, Robert S Parker, Matthew D Neal, Jason L Sperry, Gilles Clermont,

BACKGROUND:Modeling approaches offer a novel way to detect and predict coagulopathy in trauma patients. A dynamic model, built and tested on thromboelastogram (TEG) data, was used to generate a virtual library of over 160,000 simulated RapidTEGs. The patient-specific parameters are the initial platelet count, platelet activation rate, thrombus growth rate, ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2020, 88(5):654-660]

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Platelet Activation and Endothelial Cell Dysfunction.

Tom van der Poll, Robert I Parker,

In sepsis, coagulation is activated and there is an increased risk of developing a consumptive coagulopathy with attendant increase in mortality. The processes that regulate hemostasis evolved as a component of the inflammatory response to infection. Many points of interaction occur on the endothelial cell surface linking the 2 cell types ... Read more >>

Crit Care Clin (Critical care clinics)
[2020, 36(2):233-253]

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A new space-borne perspective of crop productivity variations over the US Corn Belt

Peter Somkuti, Hartmut Bösch, Liang Feng, Paul I Palmer, Robert J Parker, Tristan Quaife,

Remotely-sensed solar-induced chlorophyll fluorescence (SIF) provides a means to assess vegetation productivity in a more direct way than via the greenness of leaves. SIF is produced by plants alongside photosynthesis so it is generally thought to provide a more direct probe of plant status. We analyze inter-annual variations of SIF ... Read more >>

(Agricultural and Forest Meteorology)
[2020, 281:Not Available]

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Curative Surgery Improves Survival for Colorectal Cancer in Rural Kenya.

Robert K Parker, Michael M Mwachiro, Sinkeet S Ranketi, Faith C Mogambi, Hillary M Topazian, Russell E White,

BACKGROUND/AIMS:Colorectal cancer (CRC) is increasing in low- and middle-income countries. Surgical care is essential for the treatment. Many patients do not have access to curative surgery for colorectal cancer in rural Kenya. To better understand the impact of surgical care on colorectal cancer in a resource-limited setting, we compared the ... Read more >>

World J Surg (World journal of surgery)
[2020, 44(1):30-36]

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Mortality Prediction in Rural Kenya: A Cohort Study of Mechanical Ventilation in Critically Ill Patients.

Robert K Parker, Elizabeth B Mwachiro, Michael M Mwachiro, Jocelyn Pletcher, Andrea S Parker, Heath R Many,

Critical care is expanding in low- and middle-income countries. Yet, due to factors such as missing data and different disease patterns, predictive scores often fail to adequately predict the high rates of mortality observed. Objectives:We evaluated multiple prognostic models for the outcome of mortality in critically ill, mechanically ventilated patients ... Read more >>

Crit Care Explor (Critical care explorations)
[2019, 1(12):e0067]

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Physical activity rates in children and adolescents with autism spectrum disorder compared to the general population.

Jean-G Gehricke, James Chan, Justin G Farmer, Rachel M Fenning, Robin Steinberg-Epstein, Madhusmita Misra, Robert A Parker, Ann M Neumeyer,

Physical activity may improve symptoms and skill deficits associated with autism spectrum disorder (ASD). The objective of this study was to compare the reported frequency of physical activity and covariates in a large sample of children with ASD with children of similar age from the general population. The sample with ... Read more >>

Res Autism Spectr Disord (Research in autism spectrum disorders)
[2020, 70:]

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Bleeding Assessment Scale in Critically Ill Children (BASIC): Physician-Driven Diagnostic Criteria for Bleeding Severity.

Marianne E Nellis, Marisa Tucci, Jacques Lacroix, Philip C Spinella, Kelly D Haque, Arabela Stock, Marie E Steiner, E Vincent S Faustino, Nicole D Zantek, Peter J Davis, Simon J Stanworth, Jill M Cholette, Robert I Parker, Pierre Demaret, Martin C J Kneyber, Robert T Russell, Paul A Stricker, Adam M Vogel, Ariane Willems, Cassandra D Josephson, Naomi L C Luban, Laura L Loftis, Stéphane Leteurtre, Christian F Stocker, Susan M Goobie, Oliver Karam, ,

OBJECTIVE:Although bleeding frequently occurs in critical illness, no published definition to date describes the severity of bleeding accurately in critically ill children. We sought to develop diagnostic criteria for bleeding severity in critically ill children. DESIGN:Delphi consensus process of multidisciplinary experts in bleeding/hemostasis in critically ill children, followed by prospective ... Read more >>

Crit. Care Med. (Critical care medicine)
[2019, 47(12):1766-1772]

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Is genetic variability in carboxylesterase-1 and carboxylesterase-2 drug metabolism an important component of personalized medicine?

S Casey Laizure, Robert B Parker,

The carboxylesterase drug hydrolysis pathway has been used extensively to improve the oral availability of drugs under the assumption that the high capacity and low substrate specificity of hydrolytic enzymes would ensure rapid, complete, and consistent conversion of prodrugs to their active metabolite. However, a growing body of literature indicates ... Read more >>

Xenobiotica (Xenobiotica; the fate of foreign compounds in biological systems)
[2020, 50(1):92-100]

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Epidemiology of intra-abdominal infection and sepsis in critically ill patients: "AbSeS", a multinational observational cohort study and ESICM Trials Group Project.

Stijn Blot, Massimo Antonelli, Kostoula Arvaniti, Koen Blot, Ben Creagh-Brown, Dylan de Lange, Jan De Waele, Mieke Deschepper, Yalim Dikmen, George Dimopoulos, Christian Eckmann, Guy Francois, Massimo Girardis, Despoina Koulenti, Sonia Labeau, Jeffrey Lipman, Fernando Lipovestky, Emilio Maseda, Philippe Montravers, Adam Mikstacki, José-Artur Paiva, Cecilia Pereyra, Jordi Rello, Jean-Francois Timsit, Dirk Vogelaers, ,

PURPOSE:To describe the epidemiology of intra-abdominal infection in an international cohort of ICU patients according to a new system that classifies cases according to setting of infection acquisition (community-acquired, early onset hospital-acquired, and late-onset hospital-acquired), anatomical disruption (absent or present with localized or diffuse peritonitis), and severity of disease expression ... Read more >>

Intensive Care Med (Intensive Care Medicine)
[2019, 45(12):1703-1717]

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2520. Resource utilization in adolescents and young adults with HIV in the HIV Research Network.

Anne M Neilan, Frances Lu, Kelly Gebo, Rebeca Diaz-Reyez, Mingshu Huang, Robert Parker, Brad Karalius, Kunjal Patel, Cindy Voss, Andrea Ciaranello, Allison Agwu,

AbstractBackgroundAdolescents and young adults (AYA) with HIV experience worse health outcomes than adults with HIV in the United States. Little is known about AYA patterns of utilization of costly healthcare resources.MethodsWe estimated utilization of outpatient, emergency department (ED), and inpatient care among 13–30 year-olds from 2006–2015. We stratified outpatient visits, ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2019, 6(Suppl 2):S875-S876]

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Hemostasis in Critical Illness: Better Tools, Better Answers!

Robert I Parker,

Pediatr Crit Care Med (Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies)
[2019, 20(10):986-987]

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Cancer and Sepsis: Adding Insult to Injury-As if Either Alone Were Not Enough?

Robert I Parker,

Crit. Care Med. (Critical care medicine)
[2019, 47(10):1452-1453]

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Assessing rates and contextual predictors of 5-year mortality among HIV-infected and HIV-uninfected individuals following HIV testing in Durban, South Africa.

Ingrid V Bassett, Ai Xu, Janet Giddy, Laura M Bogart, Andrew Boulle, Lucia Millham, Elena Losina, Robert A Parker,

BACKGROUND:Little is known about contextual factors that predict long-term mortality following HIV testing in resource-limited settings. We evaluated the impact of contextual factors on 5-year mortality among HIV-infected and HIV-uninfected individuals in Durban, South Africa. METHODS:We used data from the Sizanani trial (NCT01188941) in which adults (≥18y) were enrolled prior ... Read more >>

BMC Infect. Dis. (BMC infectious diseases)
[2019, 19(1):751]

Cited: 1 time

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