Full Text Journal Articles by
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Safety and tolerability of lumateperone 42 mg: An open-label antipsychotic switch study in outpatients with stable schizophrenia.

Christoph U Correll, Kimberly E Vanover, Robert E Davis, Richard Chen, Andrew Satlin, Sharon Mates,

Lumateperone is a mechanistically novel agent FDA-approved for the treatment of schizophrenia. Efficacy and favorable tolerability of lumateperone were demonstrated in 2 short-term placebo-controlled studies in patients with schizophrenia. This open-label study investigated the short-term safety/tolerability of lumateperone in outpatients with stable schizophrenia switched from previous antipsychotic treatment. Adult outpatients ... Read more >>

Schizophr Res (Schizophrenia research)
[2021, 228:198-205]

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Explaining Handwashing Behavior in a Sample of College Students during COVID-19 Pandemic Using the Multi-Theory Model (MTM) of Health Behavior Change: A Single Institutional Cross-Sectional Survey.

Manoj Sharma, Kavita Batra, Robert E Davis, Amanda H Wilkerson,

Amidst the COVID-19 pandemic, handwashing offers a simple and effective hygienic measure for disease prevention. Reportedly, a significant proportion of college students did not follow handwashing recommendations provided by the Centers for Disease Control and Prevention (CDC) in the pre-COVID era. The purpose of this cross-sectional study was to explore ... Read more >>

Healthcare (Basel) (Healthcare (Basel, Switzerland))
[2021, 9(1):]

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Incidence of Recurrent Exertional Heat Stroke in a Warm-Weather Road Race.

Rebecca L Stearns, Yuri Hosokawa, William M Adams, Luke N Belval, Robert A Huggins, John F Jardine, Rachel K Katch, Robert J Davis, Douglas J Casa,

<i>Background and Objectives:</i> Exertional heat stroke (EHS) survivors may be more susceptible to subsequent EHS; however, the occurrence of survivors with subsequent EHS episodes is limited. Therefore, the purpose of this study was to evaluate the incidence of participants with repeated EHS (EHS-2+) cases in a warm-weather road race across ... Read more >>

Medicina (Kaunas) (Medicina (Kaunas, Lithuania))
[2020, 56(12):]

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Joint Associations of Maternal-Fetal APOL1 Genotypes and Maternal Country of Origin With Preeclampsia Risk.

Xiumei Hong, Avi Z Rosenberg, Boyang Zhang, Elizabeth Binns-Roemer, Victor David, Yiming Lv, Rebecca C Hjorten, Kimberly J Reidy, Teresa K Chen, Guoying Wang, Yuelong Ji, Claire L Simpson, Robert L Davis, Jeffrey B Kopp, Xiaobin Wang, Cheryl A Winkler,

<h4>Rationale & objective</h4>Preeclampsia, disproportionately affecting Black women, is a leading cause of preterm delivery and risk for future hypertension and chronic kidney disease (CKD). Apolipoprotein L1 (APOL1) kidney risk alleles, common among Blacks, contribute substantially to CKD disparities. Given the strong link between preeclampsia and CKD, we investigated whether maternal ... Read more >>

Am J Kidney Dis (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2020, :]

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Lighting the Patient Room of the Future: Evaluating Different Lighting Conditions for Performing Typical Nursing Tasks.

Ethan Graves, Robert G Davis, Jennifer DuBose, Gabrielle C Campiglia, Andrea Wilkerson, Craig Zimring,

<h4>Purpose</h4>This study explores how aspects of lighting in patient rooms are experienced and evaluated by nurses while performing simulated work under various lighting conditions. The lighting conditions studied represent design standards consistent with different environments of care-traditional, contemporary, and future.<h4>Background</h4>Recent advances in lighting research and technology create opportunities to use ... Read more >>

HERD (HERD)
[2020, :1937586720972078]

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Candidatus-Phytoplasma-Solani"-Strains-Associated-with-Grapevine-Bois-Noir.">Multilocus Genotyping Reveals New Molecular Markers for Differentiating Distinct Genetic Lineages among "Candidatus Phytoplasma Solani" Strains Associated with Grapevine Bois Noir.

Alessandro Passera, Yan Zhao, Sergio Murolo, Roberto Pierro, Emilija Arsov, Nicola Mori, Abdelhameed Moussa, Maria R Silletti, Paola Casati, Alessandra Panattoni, Wei Wei, Sasa Mitrev, Alberto Materazzi, Andrea Luvisi, Gianfranco Romanazzi, Piero A Bianco, Robert E Davis, Fabio Quaglino,

Grapevine Bois noir (BN) is associated with infection by "<i>Candidatus</i> Phytoplasma solani" (CaPsol). In this study, an array of CaPsol strains was identified from 142 symptomatic grapevines in vineyards of northern, central, and southern Italy and North Macedonia. Molecular typing of the CaPsol strains was carried out by analysis of ... Candidatus-Phytoplasma-Solani"-Strains-Associated-with-Grapevine-Bois-Noir.">Read more >>

Pathogens (Pathogens (Basel, Switzerland))
[2020, 9(11):]

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Candidatus-Phytoplasma-Solani"-Strains-Associated-with-Grapevine-Bois-Noir.">View full text PDF listing >>



Implementing an Urban Public Health Observatory for (Near) Real-Time Surveillance for the COVID-19 Pandemic.

Whitney S Brakefield, Nariman Ammar, Olufunto Olusanya, Esra Ozdenerol, Fridtjof Thomas, Altha J Stewart, Karen C Johnson, Robert L Davis, David L Schwartz, Arash Shaban-Nejad,

The COVID-19 pandemic is broadly undercutting global health and economies, while disproportionally impacting socially disadvantaged populations. An impactful pandemic surveillance solution must draw from multi-dimensional integration of social determinants of health (SDoH) to contextually inform traditional epidemiological factors. In this article, we describe an Urban Public Health Observatory (UPHO) model ... Read more >>

Stud Health Technol Inform (Studies in health technology and informatics)
[2020, 275:22-26]

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Person Ability Scores as an Alternative to Norm-Referenced Scores as Outcome Measures in Studies of Neurodevelopmental Disorders.

Cristan A Farmer, Aaron J Kaat, Audrey Thurm, Irina Anselm, Natacha Akshoomoff, Amanda Bennett, Leandra Berry, Aleksandra Bruchey, Bruce A Barshop, Elizabeth Berry-Kravis, Simona Bianconi, Kim M Cecil, Robert J Davis, Can Ficicioglu, Forbes D Porter, Allison Wainer, Robin P Goin-Kochel, Caroline Leonczyk, Whitney Guthrie, Dwight Koeberl, Jamie Love-Nichols, Eva Mamak, Saadet Mercimek-Andrews, Rebecca P Thomas, Gail A Spiridigliozzi, Nancy Sullivan, Vernon R Sutton, Manisha D Udhnani, Susan E Waisbren, Judith S Miller,

Although norm-referenced scores are essential to the identification of disability, they possess several features which affect their sensitivity to change. Norm-referenced scores often decrease over time among people with neurodevelopmental disorders who exhibit slower-than-average increases in ability. Further, the reliability of norm-referenced scores is lower at the tails of the ... Read more >>

Am J Intellect Dev Disabil (American journal on intellectual and developmental disabilities)
[2020, 125(6):475-480]

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Traveling for Pancreatic Cancer Care Is Worth the Trip.

Marcus A Alvarez, Kiyah Anderson, Jeremiah L Deneve, Paxton V Dickson, Danny Yakoub, Martin D Fleming, Lokesh K Chinthala, Parya Zareie, Robert L Davis, David Shibata, Evan S Glazer,

<h4>Background</h4>Centralized care for patients with pancreatic cancer is associated with longer survival. We hypothesized that increased travel distance from home is associated with increased survival for pancreatic cancer patients.<h4>Methods</h4>The National Cancer Database user file for all pancreatic cancer patients was investigated from 2004 through 2015. Distance from the patients' zip ... Read more >>

Am Surg (The American surgeon)
[2020, :3134820951484]

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Machine Learning to Develop and Internally Validate a Predictive Model for Post-operative Delirium in a Prospective, Observational Clinical Cohort Study of Older Surgical Patients.

Annie M Racine, Douglas Tommet, Madeline L D'Aquila, Tamara G Fong, Yun Gou, Patricia A Tabloski, Eran D Metzger, Tammy T Hshieh, Eva M Schmitt, Sarinnapha M Vasunilashorn, Lisa Kunze, Kamen Vlassakov, Ayesha Abdeen, Jeffrey Lange, Brandon Earp, Bradford C Dickerson, Edward R Marcantonio, Jon Steingrimsson, Thomas G Travison, Sharon K Inouye, Richard N Jones, ,

<h4>Background</h4>Our objective was to assess the performance of machine learning methods to predict post-operative delirium using a prospective clinical cohort.<h4>Methods</h4>We analyzed data from an observational cohort study of 560 older adults (≥ 70 years) without dementia undergoing major elective non-cardiac surgery. Post-operative delirium was determined by the Confusion Assessment Method supplemented by ... Read more >>

J Gen Intern Med (Journal of general internal medicine)
[2020, :]

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Safety, Tolerability, and Outcomes of Enteral Nutrition in Extracorporeal Membrane Oxygenation.

Robert C Davis, Lucian A Durham, Laszlo Kiraly, Jayshil J Patel,

Extracorporeal membrane oxygenation (ECMO) is a supportive care system for patients with respiratory or cardiac failure. Patients requiring ECMO are at risk for significant inflammation, prolonged hospitalization, and acquired malnutrition and sarcopenia. Societal guidelines recommend early enteral nutrition in critically ill patients; however, in this population, optimal timing and dose ... Read more >>

Nutr Clin Pract (Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition)
[2020, :]

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Temporal Differential Expression of Physiomarkers Predicts Sepsis in Critically Ill Adults.

Akram Mohammed, Franco Van Wyk, Lokesh K Chinthala, Anahita Khojandi, Robert L Davis, Craig M Coopersmith, Rishikesan Kamaleswaran,

<h4>Background</h4>Sepsis is a life-threatening condition with high mortality rates. Early detection and treatment are critical to improving outcomes. Our primary objective was to develop artificial intelligence capable of predicting sepsis earlier using a minimal set of streaming physiological data in real-time.<h4>Methods and findings</h4>A total of 29,552 adult patients were admitted ... Read more >>

Shock (Shock (Augusta, Ga.))
[2020, :]

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Qualitative descriptions of patient perceptions about fall risks, prevention strategies and self-identity: Analysis of fall prevention Motivational Interviewing conversations.

Hiroko Kiyoshi-Teo, Kathlynn Northrup-Snyder, Mary Robert Davis, Ellen Garcia, Amy Leatherwood, Shigeko Seiko Izumi,

<b>Background: </b>Older adults are often reluctant to engage in fall prevention activities.<br><br><b>Objectives: </b>To understand how older adults respond to fall prevention and identify attributes that affect their responses to fall prevention.<br><br><b>Methods: </b>Qualitative content analysis of Fall Prevention Motivational Interviewing conversations that were conducted as an intervention for a fall prevention ... Read more >>

J Clin Nurs (Journal of clinical nursing)
[2020, 29(21-22):4281-4288]

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TRIM37 controls cancer-specific vulnerability to PLK4 inhibition.

Franz Meitinger, Midori Ohta, Kian-Yong Lee, Sadanori Watanabe, Robert L Davis, John V Anzola, Ruth Kabeche, David A Jenkins, Andrew K Shiau, Arshad Desai, Karen Oegema,

Centrosomes catalyse the formation of microtubules needed to assemble the mitotic spindle apparatus<sup>1</sup>. Centrosomes themselves duplicate once per cell cycle, in a process that is controlled by the serine/threonine protein kinase PLK4 (refs. <sup>2,3</sup>). When PLK4 is chemically inhibited, cell division proceeds without centrosome duplication, generating centrosome-less cells that exhibit ... Read more >>

Nature (Nature)
[2020, 585(7825):440-446]

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Lighting Control in Patient Rooms: Understanding Nurses' Perceptions of Hospital Lighting Using Qualitative Methods.

Lindsay J McCunn, Sarah Safranek, Andrea Wilkerson, Robert G Davis,

PURPOSE:This study differs in its methodological approach from previously published research by interpreting qualitative results against existing literature to understand how nurses conceptualize medical-surgical patient rooms as productive settings in relation to lighting, as well as the ways in which nurses believe these spaces could be enhanced for patient satisfaction. ... Read more >>

HERD (HERD)
[2020, :1937586720946669]

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A comparison of the effect of weather and climate on emergency department visitation in Roanoke and Charlottesville, Virginia.

Robert E Davis, Erin S Markle, Sara Windoloski, Margaret E Houck, Kyle B Enfield, Hyojung Kang, Robert C Balling, Damon R Kuehl, John H Burton, Wilson Farthing, Edmundo R Rubio, Wendy M Novicoff,

Compared with mortality, the impact of weather and climate on human morbidity is less well understood, especially in the cold season. We examined the relationships between weather and emergency department (ED) visitation at hospitals in Roanoke and Charlottesville, Virginia, two locations with similar climates and population demographic profiles. Using patient-level ... Read more >>

Environ Res (Environmental research)
[2020, 191:110065]

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Effects of health beliefs, social support, and self-efficacy on sun protection behaviors among medical students: testing of an extended health belief model.

Ross L Pearlman, Vaidehi Patel, Robert E Davis, Taylor S Ferris, Karen Gruszynski, Timothy Elledge, Kaustuv Bhattacharya, Vinayak K Nahar,

Sun protection behaviors (SPB) are important modifiable risk factors for skin cancer. As the most common malignancies in the world, skin cancers account for significant morbidity, mortality, and economic burden. Physicians play a key role in educating patients about proper SPB. Medical education provides the foundation for physician understanding of ... Read more >>

Arch Dermatol Res (Archives of dermatological research)
[2020, :]

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Commentary: Making lungs great again-introducing new modifications to the Toronto ex vivo lung perfusion protocol.

Samuel J Kesseli, Robert Patrick Davis, Matthew G Hartwig,

J Thorac Cardiovasc Surg (The Journal of thoracic and cardiovascular surgery)
[2020, :]

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Sensitivity of Clinical Pediatric Obesity Diagnosis Documented in Electronic Health Records.

Christine B San Giovanni, Myla Ebeling, Robert A Davis, C Shaun Wagner, William T Basco,

<i>Objective</i>. This study tested the sensitivity of obesity diagnosis in electronic health records (EHRs) using body mass index (BMI) classification and identified variables associated with obesity diagnosis. <i>Methods</i>. Eligible children aged 2 to 18 years had a calculable BMI in 2017 and had at least 1 visit in 2016 and ... Read more >>

Clin Pediatr (Phila) (Clinical pediatrics)
[2020, 59(14):1274-1281]

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Electrocardiographic changes predate Parkinson's disease onset.

Oguz Akbilgic, Rishikesan Kamaleswaran, Akram Mohammed, G Webster Ross, Kamal Masaki, Helen Petrovitch, Caroline M Tanner, Robert L Davis, Samuel M Goldman,

Autonomic nervous system involvement precedes the motor features of Parkinson's disease (PD). Our goal was to develop a proof-of-concept model for identifying subjects at high risk of developing PD by analysis of cardiac electrical activity. We used standard 10-s electrocardiogram (ECG) recordings of 60 subjects from the Honolulu Asia Aging ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):11319]

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A mid-South chronic disease registry and practice-based research network to address disparities.

Satya Surbhi, Ian M Brooks, Sohul A Shuvo, Parya Zareie, Elizabeth A Tolley, Ronald Cossman, Cardella Leak, Robert L Davis, Altha J Stewart, James E Bailey,

<h4>Objectives</h4>To describe an innovative health information technology (HIT) model for supporting community-wide health improvement through multiprovider collaboration in a regional population health registry and practice-based research network (PBRN).<h4>Study design</h4>Case study.<h4>Methods</h4>We describe the HIT data structure and governance of the Diabetes Wellness and Prevention Coalition (DWPC) Registry and PBRN based in ... Read more >>

Am J Manag Care (The American journal of managed care)
[2020, 26(7):e211-e218]

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Veterinarians' attitudes and practices regarding opioid-related vet shopping practices in tri-state Appalachian counties: an exploratory study.

Falguni C Patel, Jeffrey A Raines, Richard W Kim, Karen Gruszynski, Robert E Davis, Manoj Sharma, Gilbert Patterson, Jason W Johnson, Vinayak K Nahar,

<h4>Background</h4>The opioid crisis continues to grow in the United States with 46,700 drug overdose deaths due to opioids in 2017 alone. Vet shopping, the practice of soliciting veterinarians for prescription medications, has been receiving national media attention in recent years. A 2014 review of Prescription Monitoring Drug Programs found less ... Read more >>

BMC Vet Res (BMC veterinary research)
[2020, 16(1):210]

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Impact of Polymer-Constrained Annealing on the Properties of DNA Origami-Templated Gold Nanowires.

Tyler R Westover, Basu R Aryal, Dulashani R Ranasinghe, Bibek Uprety, John N Harb, Adam T Woolley, Robert C Davis,

DNA origami-templated fabrication enables bottom-up fabrication of nanoscale structures from a variety of functional materials, including metal nanowires. We studied the impact of low-temperature annealing on the morphology and conductance of DNA-templated nanowires. Nanowires were formed by selective seeding of gold nanorods on DNA origami and gold electroless plating of ... Read more >>

Langmuir (Langmuir : the ACS journal of surfaces and colloids)
[2020, 36(24):6661-6667]

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M205. LONG-TERM SAFETY OF LUMATEPERONE (ITI-007): METABOLIC EFFECTS IN A 1-YEAR STUDY.

Andrew Satlin, Suresh Durgam, Kimberly E Vanover, Robert E Davis, Jason Huo, Sharon Mates, Christoph Correll,

AbstractBackgroundStandard of care (SOC) treatments for schizophrenia are often associated with a spectrum of metabolic adverse effects including weight gain and increased risk of diabetes, hyperlipidemia, and hypertension. Identifying new schizophrenia treatments with a favorable weight gain and metabolic side effect profile is important in reducing patient morbidity, mortality, and ... Read more >>

Schizophr Bull (Schizophrenia bulletin)
[2020, 46(Suppl 1):S214-S214]

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The Personal Health Library: A Single Point of Secure Access to Patient Digital Health Information.

Nariman Ammar, James E Bailey, Robert L Davis, Arash Shaban-Nejad,

Traditionally, health data management has been EMR-based and mostly handled by health care providers. Mechanisms are needed to give patients more control over their health conditions. Personal Health Libraries (PHLs) provide a single point of secure access to patients' digital health information that can help empower patients to make better-informed ... Read more >>

Stud Health Technol Inform (Studies in health technology and informatics)
[2020, 270:448-452]

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