Full Text Journal Articles by
Author Robert D Mayer

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Polymorphism in the SCN9A voltage-gated sodium channel gene associated with interstitial cystitis/bladder pain syndrome.

Jay E Reeder, Timothy K Byler, David C Foster, Steve K Landas, Henry Okafor, Gillian Stearns, Ronald W Wood, Yachao Zhang, Robert D Mayer,

OBJECTIVE: To determine whether an association exists between interstitial cystitis/bladder pain syndrome (IC/BPS) and a nonsynonymous single nucleotide polymorphism in the SCN9A voltage-gated sodium channel gene previously associated with other chronic pain syndromes. MATERIALS AND METHODS: Germline deoxyribonucleic acid was sampled from archived bladder biopsy specimens from patients with a ... Read more >>

Urology (Urology)
[2013, 81(1):210.e1-4]

Cited: 10 times

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Testosterone and 17β-estradiol induce glandular prostatic growth, bladder outlet obstruction, and voiding dysfunction in male mice.

Tristan M Nicholson, Emily A Ricke, Paul C Marker, Joseph M Miano, Robert D Mayer, Barry G Timms, Frederick S vom Saal, Ronald W Wood, William A Ricke,

Benign prostatic hyperplasia (BPH) and bladder outlet obstruction (BOO) are common in older men and can contribute to lower urinary tract symptoms that significantly impact quality of life. Few existing models of BOO and BPH use physiological levels of hormones associated with disease progression in humans in a genetically manipulable ... Read more >>

Endocrinology (Endocrinology)
[2012, 153(11):5556-5565]

Cited: 53 times

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AUA guideline for the diagnosis and treatment of interstitial cystitis/bladder pain syndrome.

Philip M Hanno, David Allen Burks, J Quentin Clemens, Roger R Dmochowski, Deborah Erickson, Mary Pat Fitzgerald, John B Forrest, Barbara Gordon, Mikel Gray, Robert Dale Mayer, Diane Newman, Leroy Nyberg, Christopher K Payne, Ursula Wesselmann, Martha M Faraday, ,

PURPOSE: To provide a clinical framework for the diagnosis and treatment of interstitial cystitis/bladder pain syndrome. MATERIALS AND METHODS: A systematic review of the literature using the MEDLINE® database (search dates 1/1/83-7/22/09) was conducted to identify peer reviewed publications relevant to the diagnosis and treatment of interstitial cystitis/bladder pain syndrome. ... Read more >>

J. Urol. (The Journal of urology)
[2011, 185(6):2162-2170]

Cited: 237 times

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Early termination of a trial of mycophenolate mofetil for treatment of interstitial cystitis/painful bladder syndrome: lessons learned.

Claire C Yang, David A Burks, Kathleen J Propert, Robert D Mayer, Kenneth M Peters, J Curtis Nickel, Christopher K Payne, Mary P FitzGerald, Philip M Hanno, Toby C Chai, Karl J Kreder, Emily S Lukacz, Harris E Foster, Liyi Cen, J Richard Landis, John W Kusek, Leroy M Nyberg, ,

We evaluated the efficacy and tolerability of mycophenolate mofetil in patients with treatment refractory interstitial cystitis/painful bladder syndrome.A total of 210 patients with interstitial cystitis/painful bladder syndrome were to be randomized into a multicenter, placebo controlled trial using a 2:1 randomization. Participants in whom at least 3 interstitial cystitis/painful bladder ... Read more >>

J Urol (The Journal of urology)
[2011, 185(3):901-906]

Cited: 7 times

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Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome.

Harris E Foster, Philip M Hanno, J Curtis Nickel, Christopher K Payne, Robert D Mayer, David A Burks, Claire C Yang, Toby C Chai, Karl J Kreder, Kenneth M Peters, Emily S Lukacz, Mary P FitzGerald, Liyi Cen, J Richard Landis, Kathleen J Propert, Wei Yang, John W Kusek, Leroy M Nyberg, ,

Amitriptyline is frequently used to treat patients with interstitial cystitis/painful bladder syndrome. The evidence to support this practice is derived mainly from a small, single site clinical trial and case reports.We conducted a multicenter, randomized, double-blind, placebo controlled clinical trial of amitriptyline in subjects with interstitial cystitis/painful bladder syndrome who ... Read more >>

J Urol (The Journal of urology)
[2010, 183(5):1853-1858]

Cited: 54 times

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Sacral nerve stimulation: neuromodulation for voiding dysfunction and pain.

Robert D Mayer, Fred M Howard,

Voiding dysfunction, which includes incontinence, retention, and chronic pelvic pain, is a relatively frequent problem that can be difficult to manage. Neuromodulation via stimulation of the sacral nerves has been shown to improve these symptoms, although the exact mechanisms remain elusive. Techniques for nerve stimulation may vary, depending on the ... Read more >>

Neurotherapeutics (Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics)
[2008, 5(1):107-113]

Cited: 19 times

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American Urological Association Northeastern Section 2007 Annual Meeting, Rochester, NY, September 6-9, 2007.

Can Urol Assoc J (Canadian Urological Association journal = Journal de l'Association des urologues du Canada)
[2007, 1(3):305-332]

Cited: 2 times

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Use of the Agency for Health Care Policy and Research Urinary Incontinence Guideline in nursing homes.

Nancy M Watson, Carol A Brink, James G Zimmer, Robert D Mayer,

The objective of this study was to assess the use of the Agency for Health Care Policy and Research (now called the Agency for Healthcare Research and Quality) Urinary Incontinence (UI) Guideline (1996) in nursing homes (NHs) using retrospective chart review and nursing assistant screening interviews. The study was conducted ... Read more >>

J Am Geriatr Soc (Journal of the American Geriatrics Society)
[2003, 51(12):1779-1786]

Cited: 47 times

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Nitric oxide inhibitor N omega -nitro-l-arginine methyl ester potentiates induction of heme oxygenase-1 in kidney ischemia/reperfusion model: a novel mechanism for regulation of the oxygenase.

Robert D Mayer, Xiaojun Wang, Mahin D Maines,

The biological significance of the heme oxygenase (HO) system's response to stress reflects functions of its products-CO and bile pigments. CO is a messenger molecule, whereas bile pigments are antioxidants and modulators of cell signaling. Presently, an unexpected mechanism for sustained suprainduction of renal HO-1 following ischemia/reperfusion injury is described. ... Read more >>

J. Pharmacol. Exp. Ther. (The Journal of pharmacology and experimental therapeutics)
[2003, 306(1):43-50]

Cited: 8 times

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