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Author Rita N Bakhru

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Transitions of Care After Critical Illness-Challenges to Recovery and Adaptive Problem Solving.

Kimberley J Haines, Elizabeth Hibbert, Nina Leggett, Leanne M Boehm, Tarli Hall, Rita N Bakhru, Anthony J Bastin, Brad W Butcher, Tammy L Eaton, Wendy Harris, Aluko A Hope, James Jackson, Annie Johnson, Janet A Kloos, Karen A Korzick, Pamela Mactavish, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Andrew Slack, Dorothy Wade, Mary Still, Giora Netzer, Ramona O Hopkins, Theodore J Iwashyna, Mark E Mikkelsen, Joanne McPeake, Carla M Sevin, ,

<h4>Objectives</h4>Investigate the challenges experienced by survivors of critical illness and their caregivers across the transitions of care from intensive care to community, and the potential problem-solving strategies used to navigate these challenges.<h4>Design</h4>Qualitative design-data generation via interviews and data analysis via the framework analysis method.<h4>Setting</h4>Patients and caregivers from three continents, identified ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(11):1923-1931]

Cited: 0 times

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Activity Levels in Survivors of the Intensive Care Unit.

Sheetal Gandotra, D Clark Files, Katherine L Shields, Michael Berry, Rita N Bakhru,

<h4>Objective</h4>Limited data exist on the quantification of activity levels and functional status in critically ill patients as they transition from the intensive care unit (ICU) to the wards and, subsequently, back into the community. The physical activity of critically ill patients from their ICU stay until 7 days after hospital ... Read more >>

Phys Ther (Physical therapy)
[2021, 101(9):]

Cited: 0 times

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Optimizing Critical Illness Recovery: Perspectives and Solutions From the Caregivers of ICU Survivors.

Carla M Sevin, Leanne M Boehm, Elizabeth Hibbert, Anthony J Bastin, James C Jackson, Joel Meyer, Tara Quasim, Rita N Bakhru, Ashley Montgomery-Yates, Andrew Slack, Mary Still, Giora Netzer, Mark E Mikkelsen, Theodore J Iwashyna, Kimberley J Haines, Joanne McPeake,

<h4>Objectives</h4>To understand the unmet needs of caregivers of ICU survivors, how they accessed support post ICU, and the key components of beneficial ICU recovery support systems as identified from a caregiver perspective.<h4>Design</h4>International, qualitative study.<h4>Subjects</h4>We conducted 20 semistructured interviews with a diverse group of caregivers in the United States, the United ... Read more >>

Crit Care Explor (Critical care explorations)
[2021, 3(5):e0420]

Cited: 1 time

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Benefits of Peer Support for Intensive Care Unit Survivors: Sharing Experiences, Care Debriefing, and Altruism.

Joanne McPeake, Theodore J Iwashyna, Leanne M Boehm, Elizabeth Hibbert, Rita N Bakhru, Anthony J Bastin, Brad W Butcher, Tammy L Eaton, Wendy Harris, Aluko A Hope, James Jackson, Annie Johnson, Janet A Kloos, Karen A Korzick, Joel Meyer, Ashley Montgomery-Yates, Mark E Mikkelsen, Andrew Slack, Dorothy Wade, Mary Still, Giora Netzer, Ramona O Hopkins, Tara Quasim, Carla M Sevin, Kimberley J Haines,

<h4>Background</h4>After critical illness, patients are often left with impairments in physical, social, emotional, and cognitive functioning. Peer support interventions have been implemented internationally to ameliorate these issues.<h4>Objective</h4>To explore what patients believed to be the key mechanisms of effectiveness of peer support programs implemented during critical care recovery.<h4>Methods</h4>In a secondary analysis ... Read more >>

Am J Crit Care (American journal of critical care : an official publication, American Association of Critical-Care Nurses)
[2021, 30(2):145-149]

Cited: 2 times

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Establishing a Peer Support Program for Survivors of COVID-19: A Report From the Critical and Acute Illness Recovery Organization.

Aluko A Hope, Andrea Annie Johnson, Joanne McPeake, Hali Felt, Carla M Sevin, Mark E Mikkelsen, Theodore J Iwashyna, Caroline Lassen-Greene, Kimberley J Haines, Sachin Agarwal, Rita N Bakhru, Leanne M Boehm, Brad W Butcher, Kelly Drumright, Tammy L Eaton, Elizabeth Hibbert, Karen Sara Hoehn, David Hornstein, Heather Imperato-Shedden, James C Jackson, Janet A Kloos, Anna Lewis, Joel Meyer, Ashley Montgomery-Yates, Veronica Rojas, Christa Schorr, Dorothy Wade, Cydni Williams,

Am J Crit Care (American journal of critical care : an official publication, American Association of Critical-Care Nurses)
[2021, :e1-e5]

Cited: 0 times

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Protocol and statistical analysis plan for the PREventing cardiovascular collaPse with Administration of fluid REsuscitation during Induction and Intubation (PREPARE II) randomised clinical trial.

Derek W Russell, Jonathan D Casey, Kevin W Gibbs, James M Dargin, Derek J Vonderhaar, A M Joffe, Shekhar Ghamande, Akram Khan, Simanta Dutta, Janna S Landsperger, Sarah W Robison, Itay Bentov, Joanne M Wozniak, Susan Stempek, Heath D White, Olivia F Krol, Matthew E Prekker, Brian E Driver, Joseph M Brewer, Li Wang, Christopher John Lindsell, Wesley H Self, Todd W Rice, Matthew W Semler, David Janz, ,

<h4>Introduction</h4>Cardiovascular collapse is a common complication during tracheal intubation of critically ill adults. Whether administration of an intravenous fluid bolus prevents cardiovascular collapse during tracheal intubation remains uncertain. A prior randomised trial found fluid bolus administration to be ineffective overall but suggested potential benefit for patients receiving positive pressure ventilation ... Read more >>

BMJ Open (BMJ open)
[2020, 10(9):e036671]

Cited: 1 time

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Key Components of ICU Recovery Programs: What Did Patients Report Provided Benefit?

Joanne McPeake, Leanne M Boehm, Elizabeth Hibbert, Rita N Bakhru, Anthony J Bastin, Brad W Butcher, Tammy L Eaton, Wendy Harris, Aluko A Hope, James Jackson, Annie Johnson, Janet A Kloos, Karen A Korzick, Pamela MacTavish, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Andrew Slack, Dorothy Wade, Mary Still, Giora Netzer, Ramona O Hopkins, Mark E Mikkelsen, Theodore J Iwashyna, Kimberley J Haines, Carla M Sevin,

To understand from the perspective of patients who did, and did not attend ICU recovery programs, what were the most important components of successful programs and how should they be organized. Design:International, qualitative study. Setting:Fourteen hospitals in the United States, United Kingdom, and Australia. Patients:We conducted 66 semi-structured interviews with ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0088]

Cited: 7 times

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Bedside Ultrasonography Can and Should Be Used in the Intensive Care Unit to Evaluate Muscle Atrophy.

Jessica Ann Palakshappa, Rita N Bakhru,

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2019, 16(9):1107-1111]

Cited: 4 times

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A randomized pilot study of nitrate supplementation with beetroot juice in acute respiratory failure.

D Clark Files, Timothy Heinrich, Katherine L Shields, Nathan J Love, Carly Brailer, Rita N Bakhru, Lina Purcell, Lori Flores, Kevin Gibbs, Gary D Miller, Peter E Morris, Michael J Berry,

Nitrate rich beetroot juice (BRJ) can enhance nitric oxide signaling, leading to improved physical function in healthy and diseased populations, but its safety and biologic efficacy have not been evaluated in a critically ill population. We randomized 22 previously functional acute respiratory failure patients to either BRJ or placebo daily ... Read more >>

Nitric Oxide (Nitric oxide : biology and chemistry)
[2020, 94:63-68]

Cited: 2 times

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Implementation of an ICU Recovery Clinic at a Tertiary Care Academic Center.

Rita N Bakhru, James F Davidson, Rebeca E Bookstaver, Michael T Kenes, Stephen P Peters, Kristin G Welborn, Oksana R Creech, Peter E Morris, D Clark Files,

Post-ICU clinics may facilitate the care of survivors of critical illness, but there is a paucity of data describing post-ICU clinic implementation. We sought to describe implementation of our ICU recovery clinic, including an assessment of barriers and facilitators to clinic attendance. Design:Adults admitted to the medical ICU of a ... Read more >>

Crit Care Explor (Critical care explorations)
[2019, 1(8):e0034]

Cited: 3 times

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Enablers and Barriers to Implementing ICU Follow-Up Clinics and Peer Support Groups Following Critical Illness: The Thrive Collaboratives.

Kimberley J Haines, Joanne McPeake, Elizabeth Hibbert, Leanne M Boehm, Krishna Aparanji, Rita N Bakhru, Anthony J Bastin, Sarah J Beesley, Lynne Beveridge, Brad W Butcher, Kelly Drumright, Tammy L Eaton, Thomas Farley, Penelope Firshman, Andrew Fritschle, Clare Holdsworth, Aluko A Hope, Annie Johnson, Michael T Kenes, Babar A Khan, Janet A Kloos, Erin K Kross, Pamela Mactavish, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Howard L Saft, Andrew Slack, Joanna Stollings, Gerald Weinhouse, Jessica Whitten, Giora Netzer, Ramona O Hopkins, Mark E Mikkelsen, Theodore J Iwashyna, Carla M Sevin,

<h4>Objectives</h4>Data are lacking regarding implementation of novel strategies such as follow-up clinics and peer support groups, to reduce the burden of postintensive care syndrome. We sought to discover enablers that helped hospital-based clinicians establish post-ICU clinics and peer support programs, and identify barriers that challenged them.<h4>Design</h4>Qualitative inquiry. The Consolidated Framework ... Read more >>

Crit Care Med (Critical care medicine)
[2019, 47(9):1194-1200]

Cited: 12 times

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Association of Hyperchloremia With Unfavorable Clinical Outcomes in Adults With Diabetic Ketoacidosis.

Nathan T Goad, Rita N Bakhru, James L Pirkle, Michael T Kenes,

<h4>Objective</h4>Hyperchloremia is associated with worsened outcomes in various clinical situations; however, data are limited in patients with diabetic ketoacidosis (DKA). The purpose of this study was to determine the effect of hyperchloremia on time to DKA resolution.<h4>Methods</h4>We conducted a retrospective cohort study of adult patients admitted with incident DKA from ... Read more >>

J Intensive Care Med (Journal of intensive care medicine)
[2020, 35(11):1307-1313]

Cited: 1 time

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Sleep and Work in ICU Physicians During a Randomized Trial of Nighttime Intensivist Staffing.

Rita N Bakhru, Mathias Basner, Meeta Prasad Kerlin, Scott D Halpern, John Hansen-Flaschen, Ilene M Rosen, David F Dinges, William D Schweickert,

<h4>Objectives</h4>To compare sleep, work hours, and behavioral alertness in faculty and fellows during a randomized trial of nighttime in-hospital intensivist staffing compared with a standard daytime intensivist model.<h4>Design</h4>Prospective observational study.<h4>Setting</h4>Medical ICU of a tertiary care academic medical center during a randomized controlled trial of in-hospital nighttime intensivist staffing.<h4>Patients</h4>Twenty faculty and ... Read more >>

Crit Care Med (Critical care medicine)
[2019, 47(7):894-902]

Cited: 1 time

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Physical Function Trajectories in Survivors of Acute Respiratory Failure.

Sheetal Gandotra, James Lovato, Douglas Case, Rita N Bakhru, Kevin Gibbs, Michael Berry, D Clark Files, Peter E Morris,

RATIONALE:Survivorship from critical illness has improved; however, factors mediating the functional recovery of persons experiencing a critical illness remain incompletely understood. OBJECTIVES:To identify groups of acute respiratory failure (ARF) survivors with similar patterns of physical function recovery after discharge and to determine the characteristics associated with group membership in each ... Read more >>

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2019, 16(4):471-477]

Cited: 11 times

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Key mechanisms by which post-ICU activities can improve in-ICU care: results of the international THRIVE collaboratives.

Kimberley J Haines, Carla M Sevin, Elizabeth Hibbert, Leanne M Boehm, Krishna Aparanji, Rita N Bakhru, Anthony J Bastin, Sarah J Beesley, Brad W Butcher, Kelly Drumright, Tammy L Eaton, Thomas Farley, Penelope Firshman, Andrew Fritschle, Clare Holdsworth, Aluko A Hope, Annie Johnson, Michael T Kenes, Babar A Khan, Janet A Kloos, Erin K Kross, Belinda J MacLeod-Smith, Pamela Mactavish, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Howard L Saft, Andrew Slack, Joanna Stollings, Gerald Weinhouse, Jessica Whitten, Giora Netzer, Ramona O Hopkins, Mark E Mikkelsen, Theodore J Iwashyna, Joanne McPeake,

<h4>Objective</h4>To identify the key mechanisms that clinicians perceive improve care in the intensive care unit (ICU), as a result of their involvement in post-ICU programs.<h4>Methods</h4>Qualitative inquiry via focus groups and interviews with members of the Society of Critical Care Medicine's THRIVE collaborative sites (follow-up clinics and peer support). Framework analysis ... Read more >>

Intensive Care Med (Intensive care medicine)
[2019, 45(7):939-947]

Cited: 13 times

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Echogenicity Is Related to Skeletal Muscle Strength in Patients With Acute Respiratory Failure.

Michael J Berry, D Clark Files, Claudia L Campos, Rita N Bakhru, Brittany M Skaggs, Peter E Morris,

<h4>Purpose</h4>Patients with acute respiratory failure (ARF) show changes in skeletal muscle structure and strength. The purpose of this study was to examine the relationship between muscle thickness, echogenicity, and strength in patients with ARF.<h4>Methods</h4>Thirteen (6 females, 7 males) patients with ARF participated in the study. Knee extensor strength was measured ... Read more >>

J Cardiopulm Rehabil Prev (Journal of cardiopulmonary rehabilitation and prevention)
[2019, 39(3):E17-E20]

Cited: 1 time

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The relationship between self-report and performance-based measures of physical function following an ICU stay.

Michael J Berry, Nathan J Love, D Clark Files, Rita N Bakhru, Peter E Morris,

PURPOSE:To examine relationships between self-report and performance-based measures of physical function in ICU patients randomized to standardized rehabilitation therapy (SRT) or usual care (UC). METHODS:Physical function was assessed in 257 ICU patients using self-report (physical functioning scale of the SF-36 (SF-36 PFS)) and the functional performance inventory-short form (FPI-SF) as ... Read more >>

J Crit Care (Journal of critical care)
[2019, 51:19-23]

Cited: 3 times

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Physical function impairment in survivors of critical illness in an ICU Recovery Clinic.

Rita N Bakhru, James F Davidson, Rebecca E Bookstaver, Michael T Kenes, Kristin G Welborn, Peter E Morris, D Clark Files,

PURPOSE:The aims were to 1) determine feasibility of measuring physical function in our ICU Recovery Clinic (RC), 2) determine if physical function was associated with 6-month re-hospitalization and 1-year mortality and 3) compare ICU survivors' physical function to other comorbid populations. MATERIALS AND METHODS:We established the Wake Forest ICU RC. ... Read more >>

J Crit Care (Journal of critical care)
[2018, 45:163-169]

Cited: 6 times

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Reply: Are No, or Late, Mobility Practices Taken in Intensive Care Units without an Early Mobility Protocol?

Rita N Bakhru, William D Schweickert,

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2017, 14(1):150]

Cited: 0 times

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Intensive Care Unit Structure Variation and Implications for Early Mobilization Practices. An International Survey.

Rita N Bakhru, David J McWilliams, Douglas J Wiebe, Vicki J Spuhler, William D Schweickert,

<h4>Rationale</h4>Early mobilization (EM) improves outcomes for mechanically ventilated patients. Variation in structure and organizational characteristics may affect implementation of EM practices.<h4>Objectives</h4>We queried intensive care unit (ICU) environment and standardized ICU practices to evaluate organizational characteristics that enable EM practice.<h4>Methods</h4>We recruited 151 ICUs in France, 150 in Germany, 150 in the ... Read more >>

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2016, 13(9):1527-1537]

Cited: 31 times

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ATS Core Curriculum 2016: Part II. Adult Critical Care Medicine.

Jakob I McSparron, Margaret M Hayes, Jason T Poston, Carey C Thomson, Henry E Fessler, Renee D Stapleton, W Graham Carlos, Laura Hinkle, Kathleen Liu, Stephanie Shieh, Alyan Ali, Angela Rogers, Nirav G Shah, Donald Slack, Bhakti Patel, Krysta Wolfe, William D Schweickert, Rita N Bakhru, Stephanie Shin, Rebecca E Sell, Andrew M Luks,

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2016, 13(5):731-740]

Cited: 0 times

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Standardized Rehabilitation and Hospital Length of Stay Among Patients With Acute Respiratory Failure: A Randomized Clinical Trial.

Peter E Morris, Michael J Berry, D Clark Files, J Clifton Thompson, Jordan Hauser, Lori Flores, Sanjay Dhar, Elizabeth Chmelo, James Lovato, L Douglas Case, Rita N Bakhru, Aarti Sarwal, Selina M Parry, Pamela Campbell, Arthur Mote, Chris Winkelman, Robert D Hite, Barbara Nicklas, Arjun Chatterjee, Michael P Young,

<h4>Importance</h4>Physical rehabilitation in the intensive care unit (ICU) may improve the outcomes of patients with acute respiratory failure.<h4>Objective</h4>To compare standardized rehabilitation therapy (SRT) to usual ICU care in acute respiratory failure.<h4>Design, setting, and participants</h4>Single-center, randomized clinical trial at Wake Forest Baptist Medical Center, North Carolina. Adult patients (mean age, 58 ... Read more >>

JAMA (JAMA)
[2016, 315(24):2694-2702]

Cited: 111 times

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An Environmental Scan for Early Mobilization Practices in U.S. ICUs.

Rita N Bakhru, Douglas J Wiebe, David J McWilliams, Vicki J Spuhler, William D Schweickert,

<h4>Objective</h4>Early mobilization improves patient outcomes. However, diffusion of this intervention into standard ICU practice is unknown. Dissemination and implementation efforts may be guided by an environmental scan to detail readiness for early mobilization, current practice, and barriers to early mobilization.<h4>Design</h4>A telephone survey.<h4>Setting</h4>U.S. ICUs.<h4>Subjects</h4>Five hundred randomly selected U.S. ICUs stratified by ... Read more >>

Crit Care Med (Critical care medicine)
[2015, 43(11):2360-2369]

Cited: 33 times

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Depressive symptoms in spouses of older patients with severe sepsis, surrogate decision makers' interpretation of prognostic information, and effect of estrogen on pseudomonas in cystic fibrosis.

Rita N Bakhru, Mary McKenzie, Jason B Turowski,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2013, 187(8):888-889]

Cited: 0 times

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A randomized trial of nighttime physician staffing in an intensive care unit.

Meeta Prasad Kerlin, Dylan S Small, Elizabeth Cooney, Barry D Fuchs, Lisa M Bellini, Mark E Mikkelsen, William D Schweickert, Rita N Bakhru, Nicole B Gabler, Michael O Harhay, John Hansen-Flaschen, Scott D Halpern,

<h4>Background</h4>Increasing numbers of intensive care units (ICUs) are adopting the practice of nighttime intensivist staffing despite the lack of experimental evidence of its effectiveness.<h4>Methods</h4>We conducted a 1-year randomized trial in an academic medical ICU of the effects of nighttime staffing with in-hospital intensivists (intervention) as compared with nighttime coverage by ... Read more >>

N Engl J Med (The New England journal of medicine)
[2013, 368(23):2201-2209]

Cited: 102 times

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