Full Text Journal Articles by
Author Rita Moretti

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Behavior in subcortical vascular dementia with sight pathologies: visual hallucinations as a consequence of precocious gait imbalance and institutionalization.

Rita Moretti, Paola Caruso, Benedetta Storti, Riccardo Saro, Benedetta Kassabian, Alessia Sala, Anna Giannini, Silvia Gazzin,

BACKGROUND:Subcortical vascular dementia (sVAD) is considered the most frequent dementia in old population, and it is due to a small vessel disease. It has a very specific nosography, where the dominant factors are dysexecutive functions, depression, and apathy. Very few studies described visual hallucinations in sVAD, apart from in the ... Read more >>

Neurol. Sci. (Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology)
[2020, :]

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Small Vessel Disease-Related Dementia: An Invalid Neurovascular Coupling?

Rita Moretti, Paola Caruso,

The arteriosclerosis-dependent alteration of brain perfusion is one of the major determinants in small vessel disease, since small vessels have a pivotal role in the brain's autoregulation. Nevertheless, as far as we know, endothelium distress can potentiate the flow dysregulation and lead to subcortical vascular dementia that is related to ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(3):]

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Is Parkinson's disease an unique clinical entity? Rigid or tremor dominant PD: Two faces of the same coin.

Rita Moretti, Paola Caruso, Giovanni Monguzzi, Alessia Sala, Matteo Dal Ben, Silvia Gazzin,

Parkinson's disease is one of the most described neurodegenerative pathologies; though it is one of the most complex pathologies, is not fully understood, correctly identified, with its different types of presentation, its clinical course and the neural networks involved. We report on a series consisting of 432 de novo PD ... Read more >>

J Clin Neurosci (Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia)
[2020, 74:18-24]

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B Vitamins and Fatty Acids: What Do They Share with Small Vessel Disease-Related Dementia?

Rita Moretti, Costanza Peinkhofer,

Many studies have been written on vitamin supplementation, fatty acid, and dementia, but results are still under debate, and no definite conclusion has yet been drawn. Nevertheless, a significant amount of lab evidence confirms that vitamins of the B group are tightly related to gene control for endothelium protection, act ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2019, 20(22):]

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Cerebral hemodynamic changes during motor imagery and passive robot-assisted movement of the lower limbs.

Paola Caruso, Mariana Ridolfi, Giovanni Furlanis, Miloš Ajčević, Mauro Semenic, Rita Moretti, Marcello Naccarato, Paolo Manganotti,

BACKGROUND:Neurovascular Coupling is the cerebral mechanism responsible for linking neuronal activity, cerebral metabolism and regional cerebral blood flow (CBF). The direct relation between functional brain activity during active, passive and motor imagery paradigms and changes in CBF has been widely investigated using different techniques. However, CBF changes have not been ... Read more >>

J. Neurol. Sci. (Journal of the neurological sciences)
[2019, 405:116427]

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Homocysteine: New Aspects of an Ancient Enigma.

Rita Moretti,

Cardiology (Cardiology)
[2019, 144(1-2):36-39]

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Small vessel disease to subcortical dementia: a dynamic model, which interfaces aging, cholinergic dysregulation and the neurovascular unit.

Paola Caruso, Riccardo Signori, Rita Moretti,

Background:Small vessels have the pivotal role for the brain's autoregulation. The arteriosclerosis-dependent alteration of the brain perfusion is one of the major determinants in small vessel disease. Endothelium distress can potentiate the flow dysregulation and lead to subcortical vascular dementia (sVAD). sVAD increases morbidity and disability. Epidemiological studies have shown ... Read more >>

Vasc Health Risk Manag (Vascular health and risk management)
[2019, 15:259-281]

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Cortical modulation of pupillary function: systematic review.

Costanza Peinkhofer, Gitte M Knudsen, Rita Moretti, Daniel Kondziella,

Background:The pupillary light reflex is the main mechanism that regulates the pupillary diameter; it is controlled by the autonomic system and mediated by subcortical pathways. In addition, cognitive and emotional processes influence pupillary function due to input from cortical innervation, but the exact circuits remain poorly understood. We performed a ... Read more >>

PeerJ (PeerJ)
[2019, 7:e6882]

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Non-alcoholic fatty liver disease and neurological defects.

Rita Moretti, Paola Caruso, Silvia Gazzin,

INTRODUCTION AND OBJECTIVES:Nonalcoholic fatty liver disease (NAFLD) can be considered one of the most common causes of liver disease in our days and is regarded as one of the newest vascular risk factors for cerebrovascular and other neurological diseases. MATERIALS AND METHODS:We studied a group of neurological outpatients, divided into ... Read more >>

Ann Hepatol (Annals of hepatology)
[2019, 18(4):563-570]

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Earliest Mechanisms of Dopaminergic Neurons Sufferance in a Novel Slow Progressing Ex Vivo Model of Parkinson Disease in Rat Organotypic Cultures of Substantia Nigra.

Matteo Dal Ben, Rosario Bongiovanni, Simone Tuniz, Emanuela Fioriti, Claudio Tiribelli, Rita Moretti, Silvia Gazzin,

The current treatments of Parkinson disease (PD) are ineffective mainly due to the poor understanding of the early events causing the decline of dopaminergic neurons (DOPAn). To overcome this problem, slow progressively degenerating models of PD allowing the study of the pre-clinical phase are crucial. We recreated in a short ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2019, 20(9):]

Cited: 2 times

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Focus on neuro-Behçet's disease: A review.

Paola Caruso, Rita Moretti,

Behçet's disease (BD) is a multisystemic vasculitis disorder of almost unknown etiology, which involves small and large vessels and affects both veins and arteries. BD is characterized by recurrent oral aphthae (the main and most recurrent symptoms), genital ulcers, variable skin lesions, arthritis, uveitis, and thrombophlebitis. Other reported symptoms concern ... Read more >>

Neurol India (Neurology India)
[2018, 66(6):1619-1628]

Cited: 1 time

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Cortical modulation of pupillary function: Systematic review

Costanza Peinkhofer, Gitte Moos Knudsen, Rita Moretti, Daniel Kondziella,

Background . The pupillary light reflex is the main mechanism that regulates the pupillary diameter; it is controlled by the autonomic system and mediated by subcortical pathways. In addition, cognitive and emotional processes influence pupillary function due to input from cortical innervation, but the exact circuits remain poorly understood. We ... Read more >>

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The Controversial Role of Homocysteine in Neurology: From Labs to Clinical Practice.

Rita Moretti, Paola Caruso,

Homocysteine (Hcy) is a sulfur-containing amino acid that is generated during methionine metabolism. Physiologic Hcy levels are determined primarily by dietary intake and vitamin status. Elevated plasma levels of Hcy can be caused by deficiency of either vitamin B12 or folate. Hyperhomocysteinemia (HHcy) can be responsible of different systemic and ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2019, 20(1):]

Cited: 5 times

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Vitamin D in Neurological Diseases: A Rationale for a Pathogenic Impact.

Rita Moretti, Maria Elisa Morelli, Paola Caruso,

It is widely known that vitamin D receptors have been found in neurons and glial cells, and their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical grey nuclei, and substantia nigra. Vitamin D helps the regulation of neurotrophin, neural differentiation, and maturation, through the control operation of growing ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2018, 19(8):]

Cited: 2 times

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Vitamin D in Neurological Diseases: A Rationale for a Pathogenic Impact

Rita Moretti, Maria elisa Morelli, Paola Caruso,

It is widely known that vitamin D receptors have been found in neurons and glial cells and their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical grey nuclei, and substantia nigra. The vitamin D helps the regulation of neurotrophin, neural differentiation and maturation, through the control operation of ... Read more >>

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Thalamus and Language: What do we know from vascular and degenerative pathologies.

Rita Moretti, Paola Caruso, Elena Crisman, Silvia Gazzin,

Language is a complex cognitive task that is essential in our daily life. For decades, researchers have tried to understand the different role of cortical and subcortical areas in cerebral language representations and language processing. Language-related cortical zones are richly interconnected with other cortical regions (particularly via myelinated fibre tracts), ... Read more >>

Neurol India (Neurology India)
[2018, 66(3):772-778]

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Management of restless legs syndrome in chronic liver disease: A challenge for the correct diagnosis and therapy.

Rita Moretti, Paola Caruso, Marzia Tecchiolli, Silvia Gazzin, Claudio Tiribelli,

To investigate the association between restless legs syndrome (RLS) and well-defined chronic liver disease, and the possible therapeutic options.Two hundred and eleven patients with chronic liver disease, complaining of sleep disturbances, painful leg sensation and daily sleepiness, were included. Patients with persistent alcohol intake, recent worsening of clinical conditions, or ... Read more >>

World J Hepatol (World journal of hepatology)
[2018, 10(3):379-387]

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Apathy in corticobasal degeneration: possible parietal involvement.

Rita Moretti, R Caberlotto, R Signori,

Corticobasal degeneration is a rare disorder, which usually consists of a combination of complex movement disorders, apraxia and cortical changes. Its definition is still evolving and in 2013 an international consortium tried to develop new criteria, based on a systematic literature review. Over a long period of time, we carefully ... Read more >>

Funct. Neurol. (Functional neurology)
[2017, 22(4):201-210]

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Basal ganglia: Their role in complex cognitive procedures in experimental models and in clinical practice.

Rita Moretti, Paola Caruso, Elena Crisman, Silvia Gazzin,

Apart from the well known role of the basal ganglia (BG) in motor control, their important role in regulating the cognitive functions is emerging. This article traces the scientific work that explores this role of BG in reinforcement learning, perceptual decision making, and other nonmotor pathways (speech fluency, cognition, attention ... Read more >>

Neurol India (Neurology India)
[2017, 65(4):814-825]

Cited: 4 times

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Frontal Tasks and Behavior in Rigid or Tremor-Dominant Parkinson Disease.

Rita Moretti, Vera Milner, Paola Caruso, Silvia Gazzin, Raffaella Rumiati,

Parkinson disease (PD) is not an unambiguous entity, and there is a general consensus for the statement that an akinetic-rigid dominant type of presentation has a worse prognosis, in the follow-up. The aim of our study was to examine the differences in frontal tasks and behavior, in 2 PD naive ... Read more >>

Am J Alzheimers Dis Other Demen (American journal of Alzheimer's disease and other dementias)
[2017, 32(5):300-306]

Cited: 1 time

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Vitamin D, Homocysteine, and Folate in Subcortical Vascular Dementia and Alzheimer Dementia.

Rita Moretti, Paola Caruso, Matteo Dal Ben, Corrado Conti, Silvia Gazzin, Claudio Tiribelli,

Dementia is a worldwide health problem which affects millions of patients; Alzheimer's disease (AD) and subcortical vascular dementia (sVAD) are the two most frequent forms of its presentation. As no definite therapeutic options have been discovered, different risk factors for cognitive impairment have been searched for potential therapies. This report ... Read more >>

Front Aging Neurosci (Frontiers in aging neuroscience)
[2017, 9:169]

Cited: 9 times

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Thiamine and Alcohol for Brain Pathology: Super-imposing or Different Causative Factors for Brain Damage?

Rita Moretti, Paola Caruso, Matteo Dal Ben, Silvia Gazzin, Claudio Tiribelli,

BACKGROUND:Drinking more than the recommended limits is a worldwide emerging problem, difficult to circumscribe, and alcohol-related brain damages are an under-recognized health problem. Alcohol-cognitive disruption can be considered as transient and recoverable if the alcohol consumption is limited and occasional; if not, it can progress to the so-called Alcohol-Related Dementia ... Read more >>

Curr Drug Abuse Rev (Current drug abuse reviews)
[2017, 10(1):44-51]

Cited: 2 times

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Rivastigmine as a Symptomatic Treatment for Apathy in Parkinson's Dementia Complex: New Aspects for This Riddle.

Rita Moretti, Paola Caruso, Matteo Dal Ben,

Over 90% of PDD patients show at least one neuropsychiatric symptom (NPS); in the 60-70% two or more NPS are present. Their incidence is important in terms of prognosis and severity of pathology. However, among all NPS, apathy is often the most disturbing, associated with greater caregiver's burden. Similar to ... Read more >>

Parkinsons Dis (Parkinson's disease)
[2017, 2017:6219851]

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Complex neurological symptoms in bilateral thalamic stroke due to Percheron artery occlusion.

Paola Caruso, Paolo Manganotti, Rita Moretti,

The artery of Percheron is a rare anatomical variant where a single thalamic perforating artery arises from the proximal posterior cerebral artery (P1 segment) between the basilar artery and the posterior communicating artery and supplies the rostral mesencephalon and both paramedian territories of the thalami. Almost one-third of human brains ... Read more >>

Vasc Health Risk Manag (Vascular health and risk management)
[2017, 13:11-14]

Cited: 2 times

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Neural Correlates for Apathy: Frontal-Prefrontal and Parietal Cortical- Subcortical Circuits.

Rita Moretti, Riccardo Signori,

Apathy is an uncertain nosographical entity, which includes reduced motivation, abulia, decreased empathy, and lack of emotional involvement; it is an important and heavy-burden clinical condition which strongly impacts in everyday life events, affects the common daily living abilities, reduced the inner goal directed behavior, and gives the heaviest burden ... Read more >>

Front Aging Neurosci (Frontiers in aging neuroscience)
[2016, 8:289]

Cited: 14 times

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