Full Text Journal Articles by
Author Richard Gast

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Spatiotemporal features of β-γ phase-amplitude coupling in Parkinson's disease derived from scalp EEG.

Ruxue Gong, Mirko Wegscheider, Christoph Mühlberg, Richard Gast, Christopher Fricke, Jost-Julian Rumpf, Vadim V Nikulin, Thomas R Knösche, Joseph Classen,

Abnormal phase-amplitude coupling between β and broadband-γ activities has been identified in recordings from the cortex or scalp of patients with Parkinson's disease. While enhanced phase-amplitude coupling has been proposed as a biomarker of Parkinson's disease, the neuronal mechanisms underlying the abnormal coupling and its relationship to motor impairments in ... Read more >>

Brain (Brain : a journal of neurology)
[2020, :]

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Research Note: Horizontal transmission and internal organ colonization by Salmonella Enteritidis and Salmonella Kentucky in experimentally infected laying hens in indoor cage-free housing.

Richard K Gast, Deana R Jones, Rupa Guraya, Kenneth E Anderson, Darrin M Karcher,

The transmission of Salmonella to humans via contaminated eggs is an international public health concern. S. Enteritidis is deposited inside eggs after colonizing reproductive tissues of infected hens. Diverse housing facility characteristics and flock management practices influence Salmonella persistence and transmission in poultry, but the food safety consequences of different ... Read more >>

Poult Sci (Poultry science)
[2020, 99(11):6071-6074]

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A Mean-Field Description of Bursting Dynamics in Spiking Neural Networks with Short-Term Adaptation.

Richard Gast, Helmut Schmidt, Thomas R Knösche,

Bursting plays an important role in neural communication. At the population level, macroscopic bursting has been identified in populations of neurons that do not express intrinsic bursting mechanisms. For the analysis of phase transitions between bursting and non-bursting states, mean-field descriptions of macroscopic bursting behavior are a valuable tool. In ... Read more >>

Neural Comput (Neural computation)
[2020, 32(9):1615-1634]

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Pooling of Laying Hen Environmental Swabs and Efficacy of Salmonella Detection.

Deana R Jones, Richard K Gast, Prafulla Regmi, Garrett E Ward, Kenneth E Anderson, Darrin M Karcher,

ABSTRACT:Environmental testing for Salmonella Enteritidis is required for U.S. shell egg producers with ≥3,000 hens on a farm. The egg producer assumes all costs for the mandatory testing. According to the U.S. Food and Drug Administration (FDA) Egg Rule, either manure scraper or drag swabs can be collected according to ... Read more >>

J Food Prot (Journal of food protection)
[2020, 83(6):943-950]

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Low Dose Infection of Hens in Lay with Salmonella enterica Serovar Enteritidis from Different Genomic Clades.

Jean Guard, Michael Rothrock, Deana Jones, Richard Gast,

Salmonella enterica serovar Enteritidis is the leading cause of salmonellosis in people, and modeling of infections in chickens is used to identify intervention strategies. A review of 80 manuscripts encompassing 119 experiments indicated that the mean dose of infection was 108 CFU per bird. Experiments of less than 106 CFU ... Read more >>

Avian Dis (Avian diseases)
[2020, 64(1):7-15]

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Probing neural networks for dynamic switches of communication pathways.

Holger Finger, Richard Gast, Christian Gerloff, Andreas K Engel, Peter König,

Dynamic communication and routing play important roles in the human brain in order to facilitate flexibility in task solving and thought processes. Here, we present a network perturbation methodology that allows investigating dynamic switching between different network pathways based on phase offsets between two external oscillatory drivers. We apply this ... Read more >>

PLoS Comput Biol (PLoS computational biology)
[2019, 15(12):e1007551]

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PyRates-A Python framework for rate-based neural simulations.

Richard Gast, Daniel Rose, Christoph Salomon, Harald E Möller, Nikolaus Weiskopf, Thomas R Knösche,

In neuroscience, computational modeling has become an important source of insight into brain states and dynamics. A basic requirement for computational modeling studies is the availability of efficient software for setting up models and performing numerical simulations. While many such tools exist for different families of neural models, there is ... Read more >>

PLoS One (PloS one)
[2019, 14(12):e0225900]

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Contamination of eggs by Salmonella Enteritidis in experimentally infected laying hens of four commercial genetic lines in conventional cages and enriched colony housing.

Richard K Gast, Prafulla Regmi, Rupa Guraya, Deana R Jones, Kenneth E Anderson, Darrin M Karcher,

Human illness caused by the consumption of eggs contaminated with Salmonella Enteritidis is a continuing international public health concern. This pathogen is deposited inside the edible contents of eggs as a consequence of its ability to colonize reproductive tissues in infected hens. Conditions in the housing environment can influence the ... Read more >>

Poult Sci (Poultry science)
[2019, 98(10):5023-5027]

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PyRates – A Python Framework for rate-based neural Simulations

Richard Gast, Daniel Rose, Harald Möller, Nikolaus Weiskopf, Thomas Knösche,

Abstract In neuroscience, computational modeling has become an important source of insight into brain states and dynamics. A basic requirement for computational modeling studies is the availability of efficient software for setting up models and performing numerical simulations. While many such tools exist for different families of neural models, there ... Read more >>

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Colonization of internal organs by Salmonella Enteritidis in experimentally infected laying hens of four commercial genetic lines in conventional cages and enriched colony housing.

Richard K Gast, Prafulla Regmi, Rupa Guraya, Deana R Jones, Kenneth E Anderson, Darrin M Karcher,

The prevalence of Salmonella Enteritidis in commercial egg-laying flocks is a prominent public health concern because contaminated eggs cause human illness. Deposition of this pathogen inside eggs results from bacterial colonization of reproductive tissues in infected hens. Environmental conditions can influence avian Salmonella infections, but the food safety consequences of ... Read more >>

Poult Sci (Poultry science)
[2019, 98(4):1785-1790]

Cited: 1 time

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Probing Neural Networks for Dynamic Switches of Communication Pathways

Holger Finger, Richard Gast, Christian Gerloff, Andreas Engel, Peter König,

Abstract Dynamic communication and routing play important roles in the human brain to facilitate 2exibility in task solving and thought processes. Here, we present a network perturbation methodology that allows to investigate dynamic switching between different network pathways based on phase offsets between two external oscillatory drivers. We apply this ... Read more >>

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Prevalence, Persistence, and Antimicrobial Resistance of Campylobacter spp. from Eggs and Laying Hens Housed in Five Commercial Housing Systems.

Estefanía Novoa Rama, Matthew Bailey, Deana R Jones, Richard K Gast, Ken Anderson, Jagpinder Brar, Rhonda Taylor, Haley F Oliver, Manpreet Singh,

Husbandry practices for laying hens in commercial egg production is a topic of interest from a social, economic, and regulatory standpoint. Animal welfare concerns regarding the use of conventional cages have arisen and consumer perceptions of hen welfare have led to a higher demand for cage-free eggs. The aim of ... Read more >>

Foodborne Pathog Dis (Foodborne pathogens and disease)
[2018, 15(8):506-516]

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Multiplication in Egg Yolk and Survival in Egg Albumen of Genetically and Phenotypically Characterized Salmonella Enteritidis Strains.

Richard K Gast, Jean Guard, Rupa Guraya, Aude Locatelli,

Prompt refrigeration of eggs to prevent the multiplication of Salmonella Enteritidis to high levels during storage is an important practice for reducing the risk of egg-transmitted human illness. The efficacy of egg refrigeration for achieving this goal depends on the interaction among the location of contamination, the ability of contaminant ... Read more >>

J Food Prot (Journal of food protection)
[2018, 81(6):876-880]

Cited: 2 times

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Serotyping of Salmonella Enterica Isolated from Mice Caught on US Poultry Farms 1995 through 1998.

Jean Guard, David J Henzler, Hazem Ramadan, Deana R Jones, Richard K Gast, Sherrill Davison, Marc W Allard,

In this study, a collection of Salmonella enterica subspecies obtained from live mice caught on 32 poultry farms in the Northeast US between 1995 to 1998 was evaluated to provide a historical reference for serotype distribution during a time when egg contamination by serotype Enteritidis was at its peak. Of ... Read more >>

Food Saf (Tokyo) (Food safety (Tokyo, Japan))
[2018, 6(1):44-50]

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Review of egg-related salmonellosis and reduction strategies in United States, Australia, United Kingdom and New Zealand.

Kapil Chousalkar, Richard Gast, Francesca Martelli, Vivek Pande,

Globally, Salmonella enterica subsp. enterica is one of the most commonly reported causes of foodborne illness in humans. Contaminated food products of animal origin, particularly egg and egg products are frequently implicated in outbreaks of human salmonellosis. Salmonella enteritidis is frequently involved in egg and egg products-associated foodborne outbreaks in ... Read more >>

Crit Rev Microbiol (Critical reviews in microbiology)
[2018, 44(3):290-303]

Cited: 7 times

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Frequency and Duration of Fecal Shedding of Salmonella Serovars Heidelberg and Typhimurium by Experimentally Infected Laying Hens Housed in Enriched Colony Cages at Different Stocking Densities.

Richard K Gast, Rupa Guraya, Deana R Jones, Jean Guard, Kenneth E Anderson, Darrin M Karcher,

Eggs contaminated with Salmonella Enteritidis are leading sources of human salmonellosis, but Salmonella Heidelberg and Salmonella Typhimurium are also egg-associated pathogens. The management practices and housing facilities characterizing different systems for housing commercial egg flocks can influence Salmonella persistence and transmission. Animal welfare aspects of poultry housing have been widely ... Read more >>

Avian Dis (Avian diseases)
[2017, 61(3):366-371]

Cited: 2 times

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Encoding and Decoding Dynamic Sensory Signals with Recurrent Neural Networks: An Application of Conceptors to Birdsongs

Richard Gast, Patrick Faion, Kai Standvoss, Andrea Suckro, Brian Lewis, Gordon Pipa,

Abstract In a constantly changing environment the brain has to make sense of dynamic patterns of sensory input. These patterns can refer to stimuli with a complex and hierarchical structure which has to be inferred from the neural activity of sensory areas in the brain. Such areas were found to ... Read more >>

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Frequency and Duration of Fecal Shedding of Salmonella Enteritidis by Experimentally Infected Laying Hens Housed in Enriched Colony Cages at Different Stocking Densities.

Richard K Gast, Rupa Guraya, Deana R Jones, Kenneth E Anderson, Darrin M Karcher,

Human infections with Salmonella Enteritidis are often attributed to the consumption of contaminated eggs, so the prevalence of this pathogen in egg-laying poultry is an important public health risk factor. Numerous and complex environmental influences on Salmonella persistence and transmission are exerted by management practices and housing facilities used in ... Read more >>

Front Vet Sci (Frontiers in veterinary science)
[2017, 4:47]

Cited: 5 times

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Colonization of internal organs by Salmonella serovars Heidelberg and Typhimurium in experimentally infected laying hens housed in enriched colony cages at different stocking densities.

Richard K Gast, Rupa Guraya, Deana R Jones, Jean Guard, Kenneth E Anderson, Darrin M Karcher,

Contaminated eggs produced by infected commercial laying flocks are often implicated as sources of human infections with Salmonella Enteritidis, but Salmonella serovars Heidelberg and Typhimurium have also been associated with egg-transmitted illness. Contamination of the edible contents of eggs is a consequence of the colonization of reproductive tissues in systemically ... Read more >>

Poult Sci (Poultry science)
[2017, 96(5):1402-1409]

Cited: 2 times

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Metabolic parameters linked by phenotype microarray to acid resistance profiles of poultry-associated Salmonella enterica.

Jean Guard, Michael J Rothrock, Devendra H Shah, Deana R Jones, Richard K Gast, Roxana Sanchez-Ingunza, Melissa Madsen, John El-Attrache, Bwalya Lungu,

Phenotype microarrays were analyzed for 51 datasets derived from Salmonella enterica. The top 4 serotypes associated with poultry products and one associated with turkey, respectively Typhimurium, Enteritidis, Heidelberg, Infantis and Senftenberg, were represented. Datasets were partitioned initially into two clusters based on ranking by values at pH 4.5 (PM10 A03). ... Read more >>

Res. Microbiol. (Research in microbiology)
[2016, 167(9-10):745-756]

Cited: 3 times

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Colonization of internal organs by Salmonella Enteritidis in experimentally infected laying hens housed in enriched colony cages at different stocking densities.

Richard K Gast, Rupa Guraya, Deana R Jones, Kenneth E Anderson, Darrin M Karcher,

Epidemiologic analyses have linked the frequency of human infections with Salmonella enterica subspecies enterica serovar Enteritidis to the consumption of contaminated eggs and thus to the prevalence of this pathogen in commercial egg-laying flocks. Contamination of the edible contents of eggs by Salmonella Enteritidis is a consequence of the colonization ... Read more >>

Poult Sci (Poultry science)
[2016, 95(6):1363-1369]

Cited: 7 times

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Persistence of fecal shedding of Salmonella Enteritidis by experimentally infected laying hens housed in conventional or enriched cages.

Richard K Gast, Rupa Guraya, Deana R Jones, Kenneth E Anderson,

Salmonella Enteritidis can be deposited inside eggs laid by infected hens, so the prevalence of this pathogen in commercial egg-producing flocks is an important risk factor for human illness. Opportunities for the introduction, transmission, and persistence of salmonellae in poultry are potentially influenced by flock housing and management systems. Animal ... Read more >>

Poult Sci (Poultry science)
[2015, 94(7):1650-1656]

Cited: 9 times

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Recovery of Salmonella enterica serovar Enteritidis from hens initially infected with serovar Kentucky.

Jean Guard, Roxana Sanchez-Ingunza, Devendra H Shah, Michael J Rothrock, Richard K Gast, Deana R Jones,

Salmonella enterica serovars Enteritidis and Kentucky differ greatly in epidemiology. We wanted to know if the non-pathogenic serotype Kentucky impacted the recovery of the pathogen Enteritidis from chickens. To explore this issue, 4 groups of hens were treated as follows: (i) hens were inoculated orally with Kentucky and injected intramuscularly ... Read more >>

Food Chem (Food chemistry)
[2015, 189:86-92]

Cited: 3 times

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Horizontal transmission of Salmonella Enteritidis in experimentally infected laying hens housed in conventional or enriched cages.

Richard K Gast, Rupa Guraya, Deana R Jones, Kenneth E Anderson,

The majority of human illnesses caused by Salmonella Enteritidis are attributed to contaminated eggs, and the prevalence of this pathogen in commercial laying flocks has been identified as a leading epidemiologic risk factor. Flock housing and management systems can affect opportunities for the introduction, transmission, and persistence of foodborne pathogens ... Read more >>

Poult Sci (Poultry science)
[2014, 93(12):3145-3151]

Cited: 8 times

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Contamination of eggs by Salmonella Enteritidis in experimentally infected laying hens housed in conventional or enriched cages.

Richard K Gast, Rupa Guraya, Deana R Jones, Kenneth E Anderson,

Both epidemiologic analyses and active disease surveillance confirm an ongoing strong association between human salmonellosis and the prevalence of Salmonella enterica subspecies enterica serovar Enteritidis in commercial egg flocks. The majority of human illnesses caused by this pathogen are attributed to the consumption of contaminated eggs. Animal welfare concerns have ... Read more >>

Poult. Sci. (Poultry science)
[2014, 93(3):728-733]

Cited: 13 times

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