Full Text Journal Articles by
Author Richard F Howard

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Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission.

Christopher Eccleston, Emma Fisher, Richard F Howard, Rebeccah Slater, Paula Forgeron, Tonya M Palermo, Kathryn A Birnie, Brian J Anderson, Christine T Chambers, Geert Crombez, Gustaf Ljungman, Isabel Jordan, Zachary Jordan, Caitriona Roberts, Neil Schechter, Christine B Sieberg, Dick Tibboel, Suellen M Walker, Dominic Wilkinson, Chantal Wood,

Lancet Child Adolesc Health (The Lancet. Child & adolescent health)
[2020, :]

Cited: 0 times

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A mixed-methods systematic review and meta-analysis of barriers and facilitators to paediatric symptom management at end of life.

Katie Greenfield, Simone Holley, Daniel E Schoth, Emily Harrop, Richard F Howard, Julie Bayliss, Lynda Brook, Satbir S Jassal, Margaret Johnson, Ian Wong, Christina Liossi,

BACKGROUND:Symptom management for infants, children and young people at end of life is complex and challenging due to the range of conditions and differing care needs of individuals of different ages. A greater understanding of these challenges could inform the development of effective interventions. AIM:To investigate the barriers and facilitators ... Read more >>

Palliat Med (Palliative medicine)
[2020, 34(6):689-707]

Cited: 0 times

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Pharmacological interventions for chronic pain in children: an overview of systematic reviews.

Christopher Eccleston, Emma Fisher, Tess E Cooper, Marie-Claude Grégoire, Lauren C Heathcote, Elliot Krane, Susan M Lord, Navil F Sethna, Anna-Karenia Anderson, Brian Anderson, Jacqueline Clinch, Andrew L Gray, Jeffrey I Gold, Richard F Howard, Gustaf Ljungman, R Andrew Moore, Neil Schechter, Philip J Wiffen, Nick M R Wilkinson, David G Williams, Chantal Wood, Miranda A L van Tilburg, Boris Zernikow,

We know little about the safety or efficacy of pharmacological medicines for children and adolescents with chronic pain, despite their common use. Our aim was to conduct an overview review of systematic reviews of pharmacological interventions that purport to reduce pain in children with chronic noncancer pain (CNCP) or chronic ... Read more >>

Pain (Pain)
[2019, 160(8):1698-1707]

Cited: 2 times

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Paediatric pain education for health care professionals.

Anna Hurley-Wallace, Chantal Wood, Linda S Franck, Richard F Howard, Christina Liossi,

(Pain reports)
[2019, 4(1):e701]

Cited: 1 time

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Pediatric Erythromelalgia and SCN9A Mutations: Systematic Review and Single-Center Case Series.

Luke Arthur, Kirsty Keen, Madeleine Verriotis, Judy Peters, Alison Kelly, Richard F Howard, Sulayman D Dib-Hajj, Stephen G Waxman, Suellen M Walker,

OBJECTIVES:To evaluate the clinical features of erythromelalgia in childhood associated with gain-of-function SCN9A mutations that increase activity of the Nav1.7 voltage-gated sodium channel, we conducted a systematic review of pediatric presentations of erythromelalgia related to SCN9A mutations, and compared pediatric clinical presentations of symptomatic erythromelalgia, with or without SCN9A mutations. ... Read more >>

J Pediatr (The Journal of pediatrics)
[2019, 206:217-224.e9]

Cited: 1 time

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On the Difficulties of Studying Pain Management in Individuals with Developmental Delay.

Matthew A Jay, Ben M Thomas, Reema Nandi, Richard F Howard,

Pain Med (Pain medicine (Malden, Mass.))
[2018, 19(7):1503-1504]

Cited: 0 times

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The effectiveness of online pain resources for health professionals: a systematic review with subset meta-analysis of educational intervention studies.

Christina Liossi, Alessandro Failo, Daniel E Schoth, Glyn Williams, Richard F Howard,

Online educational interventions are increasingly developed for health professionals and students, although graduate and undergraduate medical curricula often contain limited information about how to assess and manage pain. This study reviews the literature on the effectiveness of pain-related online educational resources. Studies were identified through a search of Medline, PsychINFO, ... Read more >>

Pain (Pain)
[2018, 159(4):631-643]

Cited: 2 times

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Persistent postsurgical pain in children and young people: prediction, prevention, and management.

Glyn Williams, Richard F Howard, Christina Liossi,

Ensuring optimum preoperative and postoperative pain management should always be a priority in children. ... Read more >>

Pain Rep (Pain reports)
[2017, 2(5):e616]

Cited: 13 times

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Pediatric Chronic Pain: Biopsychosocial Assessment and Formulation.

Christina Liossi, Richard F Howard,

Chronic pain in children is an increasingly recognized clinical problem with alarmingly high prevalence rates found in some populations. Although it is not understood why some children experience high levels of pain, the subjective experience of chronic pain (including its site, intensity, quality, unpleasantness, and associated suffering) has long been ... Read more >>

Pediatrics (Pediatrics)
[2016, 138(5):]

Cited: 9 times

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Development of research priorities in paediatric pain and palliative care.

Christina Liossi, Anna-Karenia Anderson, Richard F Howard, ,

Priority setting for healthcare research is as important as conducting the research itself because rigorous and systematic processes of priority setting can make an important contribution to the quality of research. This project aimed to prioritise clinical therapeutic uncertainties in paediatric pain and palliative care in order to encourage and ... Read more >>

(British journal of pain)
[2017, 11(1):9-15]

Cited: 4 times

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Inequalities in access to a tertiary children's chronic pain service: a cross-sectional study.

Matthew A Jay, Richard F Howard,

Poor health, including chronic pain, has been consistently shown to be associated with lower socioeconomic status (SES).To describe the SES of a clinical population of children with chronic pain referred to tertiary care in England, and to determine if access to, and utilisation of, the service is related to SES.Using ... Read more >>

Arch Dis Child (Archives of disease in childhood)
[2016, 101(7):657-661]

Cited: 3 times

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The anaesthetic management of conjoined twins.

Grant M Stuart, Ann E Black, Richard F Howard,

The management of anaesthesia for conjoined twins poses unique anatomical, physiological and logistic challenges. Although many possible configurations of union exist and each is unique, we describe the principles of anaesthesia for conjoined twins drawing on our institutional experience of managing 26 sets for a variety of procedures including separation. ... Read more >>

Semin. Pediatr. Surg. (Seminars in pediatric surgery)
[2015, 24(5):224-228]

Cited: 2 times

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Pain assessment in children.

Richard F Howard, Christina Liossi,

Arch Dis Child (Archives of disease in childhood)
[2014, 99(12):1123-1124]

Cited: 3 times

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Presentation and management of chronic pain.

Dilini Rajapakse, Christina Liossi, Richard F Howard,

Chronic pain is an important clinical problem affecting significant numbers of children and their families. The severity and impact of chronic pain on everyday function is shaped by the complex interaction of biological, psychological and social factors that determine the experience of pain for each individual, rather than a straightforward ... Read more >>

Arch. Dis. Child. (Archives of disease in childhood)
[2014, 99(5):474-480]

Cited: 24 times

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Neuropathic pain in children.

Richard F Howard, Suzanne Wiener, Suellen M Walker,

Neuropathic pain (NP), due to a lesion or disease of the somatosensory nervous system, is not well documented or researched in children. NP is a clinical diagnosis that can be difficult, especially in younger children. Nevertheless, it is important to recognise NP, as pain mechanisms and consequently management and prognosis ... Read more >>

Arch. Dis. Child. (Archives of disease in childhood)
[2014, 99(1):84-89]

Cited: 27 times

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Pain and behaviour changes in children following surgery.

Nina Mary Power, Richard F Howard, Angie M Wade, Linda S Franck,

OBJECTIVES: To quantify postoperative pain and problematic behaviour (PB) in children at home following day-case (same day admission and discharge) or inpatient (≥1 night in hospital) surgery, to identify factors associated with PB at 2 and 4 weeks after discharge and to determine whether pain is associated with PB after ... Read more >>

Arch. Dis. Child. (Archives of disease in childhood)
[2012, 97(10):879-884]

Cited: 35 times

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Clinical outcome of a randomized controlled blinded trial of open versus laparoscopic Nissen fundoplication in infants and children.

Merrill McHoney, Angie M Wade, Simon Eaton, Richard F Howard, Edward M Kiely, David P Drake, Joe I Curry, Agostino Pierro,

OBJECTIVE: To compare the clinical outcome and endocrine response in children who were randomized to open or laparoscopic Nissen fundoplication using minimization. BACKGROUND: It is assumed that laparoscopic surgery is associated with less pain, quicker recovery and dampened endocrine response. Few randomized studies have been performed in children. METHODS: Parents ... Read more >>

Ann Surg (Annals of surgery)
[2011, 254(2):209-216]

Cited: 19 times

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The addition of ketamine to a morphine nurse- or patient-controlled analgesia infusion (PCA/NCA) increases analgesic efficacy in children with mucositis pain.

Paul J James, Richard F Howard, David Glyn Williams,

AIM: To assess the efficacy of adding ketamine to morphine nurse- or patient-controlled analgesia (NCA/PCA) infusions in treating mucositis pain in children. BACKGROUND: Mucositis pain can be very difficult to control in some patients despite the use of parenteral opioids. In our institution, we have started adding low-dose ketamine to ... Read more >>

Paediatr Anaesth (Paediatric anaesthesia)
[2010, 20(9):805-811]

Cited: 7 times

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Nurse-controlled analgesia (NCA) following major surgery in 10,000 patients in a children's hospital.

Richard F Howard, Adrian Lloyd-Thomas, Mark Thomas, D Glyn Williams, Rebecca Saul, Elizabeth Bruce, Judy Peters,

BACKGROUND AND OBJECTIVES: Patients who received NCA with morphine following major surgery between 1996 and 2008 at Great Ormond Street Hospital, London, UK, were prospectively studied in the postoperative period to determine effectiveness, morphine requirements, incidence of common side effects, and serious adverse events. METHODS: The morphine NCA regimen and ... Read more >>

Paediatr Anaesth (Paediatric anaesthesia)
[2010, 20(2):126-134]

Cited: 26 times

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Audits of postoperative analgesia: what have we learned and what should we do now?

Richard F Howard,

Paediatr Anaesth (Paediatric anaesthesia)
[2010, 20(2):117-118]

Cited: 5 times

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Prospective observational study of adverse drug reactions to diclofenac in children.

Joseph F Standing, Kuan Ooi, Simon Keady, Richard F Howard, Imogen Savage, Ian C K Wong,

AIM: The aim of this study was to investigate the type of common (occurring in >1% of patients) adverse reactions caused by diclofenac when given to children for acute pain. METHODS: A prospective observational study was undertaken on paediatric surgical patents aged < or =12 years at Great Ormond Street ... Read more >>

Br J Clin Pharmacol (British journal of clinical pharmacology)
[2009, 68(2):243-251]

Cited: 10 times

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Developmental age influences the effect of epidural dexmedetomidine on inflammatory hyperalgesia in rat pups.

Suellen M Walker, Richard F Howard, Kevin A Keay, Maria Fitzgerald,

BACKGROUND:Epidural alpha2-adrenergic agonists produce analgesic effects in children and adults, but efficacy and safety have not been established in neonates and infants. The aim of this study was to determine the effect of epidural dexmedetomidine on sensory processing, reversal of inflammatory hyperalgesia, and sedation during early development in rats. METHODS:In ... Read more >>

Anesthesiology (Anesthesiology)
[2005, 102(6):1226-1234]

Cited: 38 times

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The efficacy of morphine and Entonox analgesia during chest drain removal in children.

Elizabeth Bruce, Linda Franck, Richard F Howard,

BACKGROUND: Morphine is commonly used for chest drain removal pain, although a few studies in adults suggest that inhalation agents may be effective for this procedure. Little is known about chest drain removal pain and its management in children. METHODS: Three separate studies were carried out at a large tertiary ... Read more >>

Paediatr Anaesth (Paediatric anaesthesia)
[2006, 16(3):302-308]

Cited: 8 times

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Chest drain removal pain and its management: a literature review.

Elizabeth A Bruce, Richard F Howard, Linda S Franck,

AIMS AND OBJECTIVES: The purpose of this review was to analyse critically the published research on chest drain removal pain and its management. The findings of descriptive and non-pharmacological intervention studies were summarized and studies of analgesic efficacy were critiqued in depth. BACKGROUND: The removal of a chest drain is ... Read more >>

J Clin Nurs (Journal of clinical nursing)
[2006, 15(2):145-154]

Cited: 14 times

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The ontogeny of neuropathic pain: postnatal onset of mechanical allodynia in rat spared nerve injury (SNI) and chronic constriction injury (CCI) models.

Richard F Howard, Suellen M Walker, P Michael Mota, Maria Fitzgerald,

Neuropathic pain is known to occur in children but remains poorly understood and treated. The aim here was to establish a model of neuropathic pain in neonatal and young rodents. In the adult the spared nerve injury (SNI) model produced robust mechanical allodynia measured as a fall in cutaneous sensory ... Read more >>

Pain (Pain)
[2005, 115(3):382-389]

Cited: 51 times

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