Full Text Journal Articles by
Author Richard D Moore

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Brief Report: Differences in Types of Myocardial Infarctions Among People Aging With HIV.

Heidi M Crane, Robin M Nance, Bridget M Whitney, Susan R Heckbert, Matthew Budoff, Kevin High, Alan Landay, Matthew Feinstein, Richard D Moore, William Christopher Mathews, Katerina Christopoulos, Michael S Saag, Amanda Willig, Joseph J Eron, Mari M Kitahata, Joseph A C Delaney, ,

<h4>Background</h4>Type 1 myocardial infarctions (T1MIs) result from atherosclerotic plaque instability, rupture, and/or erosion. Type 2 MIs (T2MIs) are secondary to causes such as sepsis and cocaine-induced vasospasm resulting in an oxygen demand-supply mismatch and are associated with higher mortality than T1MIs. T2MIs account for a higher proportion of MIs among ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2021, 86(2):208-212]

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Drug and alcohol use among people living with HIV in care in the United States by geographic region.

Heidi M Crane, Robin M Nance, Bridget M Whitney, Stephanie Ruderman, Judith I Tsui, Geetanjali Chander, Mary E McCaul, Bryan Lau, Kenneth H Mayer, D Scott Batey, Steven A Safren, Richard D Moore, Joseph J Eron, Sonia Napravnik, W Chris Mathews, Rob J Fredericksen, Andrew W Hahn, Michael J Mugavero, William B Lober, Michael S Saag, Mari M Kitahata, Joseph A C Delaney,

Substance use in the U.S. varies by geographic region. Opioid prescribing practices and marijuana, heroin, and methamphetamine availability are evolving differently across regions. We examined self-reported substance use among people living with HIV (PLWH) in care at seven sites from 2017-2019 to understand current regional substance use patterns. We calculated ... Read more >>

AIDS Care (AIDS care)
[2021, :1-8]

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Secular Trends in Breast Cancer Risk among Women with HIV Initiating ART in North America.

Sally B Coburn, Meredith Shiels, Michael Silverberg, Michael Horberg, M John Gill, Todd T Brown, Kala Visvanathan, Avonne E Connor, Sonia Napravnik, Julia Marcus, Richard D Moore, W Chris Mathews, Angel Mauricio Mayor, Timothy Sterling, Jun Li, Charles Rabkin, Gyspyamber D'Souza, Bryan Lau, Keri N Althoff, ,

<h4>Background</h4>Studies suggest lower risk of breast cancer in women with versus without HIV. These estimates may be biased by lower life expectancy and younger age distribution of women with HIV. Our analysis evaluated this bias and characterized secular trends in breast cancer among women with HIV initiating ART. We hypothesized ... Read more >>

J Acquir Immune Defic Syndr (Journal of acquired immune deficiency syndromes (1999))
[2021, :]

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The HIV Index: Using a Patient-Reported Outcome on Engagement in HIV Care to Explain Sub-Optimal Retention in Care and Virologic Control.

Katerina A Christopoulos, Torsten B Neilands, Kimberly A Koester, John A Sauceda, Samantha E Dilworth, Michael J Mugavero, Heidi M Crane, Rob J Fredericksen, Edward R Cachay, Kenneth H Mayer, Richard D Moore, Sonia Napravnik, Mallory O Johnson,

<h4>Background</h4>We investigated the prospective association between a brief self-report measure of engagement in HIV care (the Index) and suboptimal retention and viral suppression (VS) outcomes.<h4>Methods</h4>The CNICS cohort study combines medical record data with patient-reported outcomes from eight HIV clinics in the United States, which from April 2016-March 2017 included the ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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CD4 count at entry into HIV care and at antiretroviral therapy prescription in the US, 2005-2018.

Jennifer S Lee, Elizabeth A Humes, Brenna C Hogan, Kate Buchacz, Joseph J Eron, M John Gill, Timothy R Sterling, Peter F Rebeiro, Viviane Dias Lima, Angel Mayor, Michael J Silverberg, Michael A Horberg, Richard D Moore, Keri N Althoff, ,

From 2005 to 2018, among 32013 adults entering HIV care in the US, median time to ART prescription declined from 69 to 6 days, median CD4 count at entry into care increased from 300 to 362 cells/µL, and median CD4 count at ART prescription increased from 160 to 364 cells/µL. ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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Current and Past Immunodeficiency are Associated with Higher Hospitalization Rates among Persons on Virologically Suppressive Antiretroviral Therapy for up to Eleven Years.

Thibaut Davy-Mendez, Sonia Napravnik, Joseph J Eron, Stephen R Cole, David van Duin, David A Wohl, Brenna C Hogan, Keri N Althoff, Kelly A Gebo, Richard D Moore, Michael J Silverberg, Michael A Horberg, M John Gill, W Christopher Mathews, Marina B Klein, Jonathan A Colasanti, Timothy R Sterling, Angel M Mayor, Peter F Rebeiro, Kate Buchacz, Jun Li, Ni Gusti Ayu Nanditha, Jennifer E Thorne, Ank Nijhawan, Stephen A Berry, ,

<h4>Background</h4>Persons with HIV (PWH) with persistently low CD4 counts despite efficacious antiretroviral therapy could have higher hospitalization risk.<h4>Methods</h4>In six US and Canadian clinical cohorts, PWH with virologic suppression for ≥1 year in 2005-2015 were followed until virologic failure, loss to follow-up, death, or study end. Stratified by early (Years 2-5) ... Read more >>

J Infect Dis (The Journal of infectious diseases)
[2020, :]

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A learning algorithm for predicting mental health symptoms and substance use.

Anthony T Fojo, Catherine R Lesko, Kelly S Benke, Geetanjali Chander, Bryan Lau, Richard D Moore, Peter P Zandi, Scott L Zeger,

Learning health systems use data to generate knowledge that informs clinical care, but few studies have evaluated how to leverage patient-reported mental health symptoms and substance use data to make patient-specific predictions. We developed a general Bayesian prediction algorithm that uses self-reported psychiatric symptoms and substance use within a population ... Read more >>

J Psychiatr Res (Journal of psychiatric research)
[2020, 134:22-29]

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Prevalence of and Factors Associated with Genital and Extragenital Chlamydia and Gonorrhea among Transgender Women in HIV Care in the United States; 2005-2016.

Olivia T Van Gerwen, Ashutosh Tamhane, Andrew O Westfall, Michael J Mugavero, Heidi M Crane, Richard D Moore, Maile Karris, Katerina Christopoulos, Julia C Dombrowski, Kenneth H Mayer, Jeanne Marrazzo, Jodie Dionne-Odom,

<h4>Background</h4>Data on testing rates and prevalence of and factors associated with of genital and extragenital chlamydia and gonorrhea among transgender women with HIV in the United States are limited.<h4>Methods</h4>This retrospective cohort analysis included transgender women living with HIV enrolled in the U.S. Centers for AIDS Research Network of Integrated Clinical ... Read more >>

Sex Transm Dis (Sexually transmitted diseases)
[2020, :]

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Substantial decline in heavily treated therapy-experienced persons with HIV with limited antiretroviral treatment options.

Kristina L Bajema, Robin M Nance, Joseph A C Delaney, Ellen Eaton, Thibaut Davy-Mendez, Maile Y Karris, Richard D Moore, Joseph J Eron, Benigno Rodriguez, Kenneth H Mayer, Elvin Geng, Cindy Garris, Michael S Saag, Heidi M Crane, Mari M Kitahata, ,

<h4>Objective</h4>Historically, a high burden of resistance to antiretroviral therapy (ART) in heavily treatment-experienced (HTE) persons with HIV (PWH) resulted in limited treatment options (LTOs). We evaluated the prevalence, risk factors, and virologic control of HTE PWH with LTO throughout the modern ART era.<h4>Design</h4>We examined all ART-experienced PWH in care between ... Read more >>

AIDS (AIDS (London, England))
[2020, 34(14):2051-2059]

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Genetic architecture of cardiometabolic risks in people living with HIV.

Haoxiang Chang, Anshuman Sewda, Carla Marquez-Luna, Sierra R White, Bridget M Whitney, Jessica Williams-Nguyen, Robin M Nance, Won Jun Lee, Mari M Kitahata, Michael S Saag, Amanda Willig, Joseph J Eron, W Christopher Mathews, Peter W Hunt, Richard D Moore, Allison Webel, Kenneth H Mayer, Joseph A Delaney, Paul K Crane, Heidi M Crane, Ke Hao, Inga Peter,

<h4>Background</h4>Advances in antiretroviral therapies have greatly improved the survival of people living with human immunodeficiency virus (HIV) infection (PLWH); yet, PLWH have a higher risk of cardiovascular disease than those without HIV. While numerous genetic loci have been linked to cardiometabolic risk in the general population, genetic predictors of the ... Read more >>

BMC Med (BMC medicine)
[2020, 18(1):288]

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Hospitalization Rates and Causes among Persons with HIV in the US and Canada, 2005-2015.

Thibaut Davy-Mendez, Sonia Napravnik, Brenna C Hogan, Keri N Althoff, Kelly A Gebo, Richard D Moore, Michael A Horberg, Michael J Silverberg, M John Gill, Heidi M Crane, Vincent C Marconi, Ronald J Bosch, Jonathan A Colasanti, Timothy R Sterling, W Christopher Mathews, Angel M Mayor, Ni Gusti Ayu Nanditha, Kate Buchacz, Jun Li, Peter F Rebeiro, Jennifer E Thorne, Ank Nijhawan, David van Duin, David A Wohl, Joseph J Eron, Stephen A Berry, ,

<h4>Background</h4>To assess the possible impact of antiretroviral therapy improvements, aging, and comorbidities, we examined trends in all-cause and cause-specific hospitalization rates among persons with HIV (PWH) from 2005 to 2015.<h4>Methods</h4>In six clinical cohorts, we followed PWH in care (≥1 outpatient CD4 count or HIV viral load [VL] every 12 months) ... Read more >>

J Infect Dis (The Journal of infectious diseases)
[2020, :]

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Risk of Incident Diabetes Mellitus, Weight Gain, and their Relationships with Integrase Inhibitor-based Initial Antiretroviral Therapy Among Persons with HIV in the US and Canada.

Peter F Rebeiro, Cathy A Jenkins, Aihua Bian, Jordan E Lake, Kassem Bourgi, Richard D Moore, Michael A Horberg, W Christopher Matthews, Michael J Silverberg, Jennifer Thorne, Angel M Mayor, Viviane D Lima, Frank J Palella, Michael S Saag, Keri N Althoff, M John Gill, Cherise Wong, Marina B Klein, Heidi M Crane, Vincent C Marconi, Bryan E Shepherd, Timothy R Sterling, John R Koethe,

<h4>Background</h4>Integrase strand transfer inhibitor (INSTI)-based combination antiretroviral therapy (cART) is associated with greater weight gain among persons with HIV, though the metabolic consequences, such as diabetes mellitus (DM), are unclear. We examined the impact of initial cART regimen and weight on incident DM in a large North American HIV cohort ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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Estimating a Set of Mortality Risk Functions with Multiple Contributing Causes of Death.

Tiffany L Breger, Jessie K Edwards, Stephen R Cole, Michael Saag, Peter F Rebeiro, Richard D Moore, Joseph J Eron,

<h4>Background</h4>There are few methodologic examples of how multiple causes of death may be summarized in cause-specific mortality analyses to address limitations of attributing death to a single underlying cause. We propose a cause-of-death weighting approach to estimate the set of risk functions of specific causes of mortality using both underlying ... Read more >>

Epidemiology (Epidemiology (Cambridge, Mass.))
[2020, 31(5):704-712]

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Internalized HIV stigma predicts subsequent viremia in US HIV patients through depressive symptoms and antiretroviral therapy adherence.

Katerina A Christopoulos, Torsten B Neilands, Samantha Dilworth, Nadra Lisha, John Sauceda, Michael J Mugavero, Heidi M Crane, Rob J Fredericksen, William C Mathews, Richard D Moore, Kenneth H Mayer, Sonia Napravnik, Mallory O Johnson,

<h4>Objective</h4>We sought to examine the prospective association between internalized HIV stigma and unsuppressed viral load and to investigate whether this relationship was sequentially mediated by depressive symptoms and antiretroviral therapy (ART) adherence.<h4>Design</h4>Longitudinal study in a multisite observational clinical cohort.<h4>Methods</h4>The Center for AIDS Research Network of Integrated Clinical Systems patient-reported outcomes ... Read more >>

AIDS (AIDS (London, England))
[2020, 34(11):1665-1671]

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Clinical effectiveness of integrase strand transfer inhibitor-based antiretroviral regimens among adults with human immunodeficiency virus: a collaboration of cohort studies in the United States and Canada.

Haidong Lu, Stephen R Cole, Daniel Westreich, Michael G Hudgens, Adaora A Adimora, Keri N Althoff, Michael J Silverberg, Kate Buchacz, Jun Li, Jessie K Edwards, Peter F Rebeiro, Viviane D Lima, Vincent C Marconi, Timothy R Sterling, Michael A Horberg, M John Gill, Mari M Kitahata, Joseph J Eron, Richard D Moore, ,

BACKGROUND:Integrase strand transfer inhibitor (InSTI)-based regimens are now recommended as first-line antiretroviral therapy (ART) for adults with human immunodeficiency virus. But evidence on long-term clinical effectiveness of InSTI-based regimens remains limited. We examined whether InSTI-based regimens improved longer-term clinical outcomes. METHODS:We included participants from clinical cohorts in the North American ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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Internalized HIV stigma predicts subsequent viremia in US HIV patients through depressive symptoms and ART adherence.

Katerina A Christopoulos, Torsten B Neilands, Samantha Dilworth, Nadra Lisha, John Sauceda, Michael J Mugavero, Heidi M Crane, Rob J Fredericksen, W Christopher Mathews, Richard D Moore, Kenneth H Mayer, Sonia Napravnik, Mallory O Johnson,

<h4>Objective</h4>We sought to examine the prospective association between internalized HIV stigma and unsuppressed viral load and to investigate whether this relationship was sequentially mediated by depressive symptoms and antiretroviral (ART) adherence.<h4>Design</h4>Longitudinal study in a multi-site observational clinical cohort.<h4>Methods</h4>The Center for AIDS Research Network of Integrated Clinical Systems (CNICS) Patient-Reported Outcomes ... Read more >>

AIDS (AIDS (London, England))
[2020, :]

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Timing of Antiretroviral Therapy Initiation and Risk of Cancer among Persons Living with HIV.

Michael J Silverberg, Wendy Leyden, Raúl U Hernández-Ramírez, Li Qin, Haiqun Lin, Amy C Justice, Nancy A Hessol, Chad J Achenbach, Gypsyamber D'Souza, Eric A Engels, Keri N Althoff, Angel M Mayor, Timothy R Sterling, Mari M Kitahata, Ronald J Bosch, Michael S Saag, Charles S Rabkin, Michael A Horberg, M John Gill, Surbhi Grover, W Christopher Mathews, Jun Li, Heidi M Crane, Stephen J Gange, Bryan Lau, Richard D Moore, Robert Dubrow, Romain S Neugebauer, ,

BACKGROUND:Persons living with HIV (PLWH) experience a high burden of cancer. It remains unknown which cancer types are reduced in PLWH with earlier initiation of antiretroviral therapy (ART). METHODS:We evaluated AIDS-free, ART-naive PLWH during 1996-2014 from 22 cohorts participating in the North American AIDS Cohort Collaboration on Research and Design. ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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Variation in estimated viral suppression associated with the definition of viral suppression used.

Catherine R Lesko, Geetanjali Chander, Richard D Moore, Bryan Lau,

<h4>Objective</h4>The proportion of people living with HIV with suppressed viral load is a key indicator of the HIV care continuum. We explored how this proportion varied depending on how it was calculated.<h4>Design</h4>Observational cohort study.<h4>Methods</h4>We calculated the proportion of the Johns Hopkins HIV Clinical Cohort who were virally suppressed each year, ... Read more >>

AIDS (AIDS (London, England))
[2020, 34(10):1519-1526]

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Desperate Times: Protecting the Public From Research Without Consent or Oversight During Public Health Emergencies.

Mary Catherine Beach, Howard M Lederman, Megan Singleton, Roy G Brower, Joseph Carrese, Daniel E Ford, Bhakti Hansoti, Craig W Hendrix, Ellen Verena Jorgensen, Richard D Moore, Philip Rocca, Jonathan M Zenilman,

Ann Intern Med (Annals of internal medicine)
[2020, 173(11):926-928]

Cited: 1 time

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Association Between Chronic Hepatitis C Virus Infection and Myocardial Infarction Among People Living With HIV in the United States.

Jessica Williams-Nguyen, Stephen E Hawes, Robin M Nance, Sara Lindström, Susan R Heckbert, H Nina Kim, W Chris Mathews, Edward R Cachay, Matt Budoff, Christopher B Hurt, Peter W Hunt, Elvin Geng, Richard D Moore, Michael J Mugavero, Inga Peter, Mari M Kitahata, Michael S Saag, Heidi M Crane, Joseph A Delaney,

Hepatitis C virus (HCV) infection is common among people living with human immunodeficiency virus (PLWH). Extrahepatic manifestations of HCV, including myocardial infarction (MI), are a topic of active research. MI is classified into types, predominantly atheroembolic type 1 MI (T1MI) and supply-demand mismatch type 2 MI (T2MI). We examined the ... Read more >>

Am J Epidemiol (American journal of epidemiology)
[2020, 189(6):554-563]

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Impact of Early Antiretroviral Treatment Initiation on Performance of Cross-Sectional Incidence Assays.

Ethan Klock, George Mwinnya, Leigh Anne Eller, Reinaldo E Fernandez, Hannah Kibuuka, Sorachai Nitayaphan, Josphat Kosgei, Richard D Moore, Merlin Robb, Susan H Eshleman, Oliver Laeyendecker,

Antiretroviral therapy (ART) can impact assays used for cross-sectional HIV incidence testing, causing inaccurate HIV incidence estimates. We evaluated the relationship between the timing of ART initiation and the performance of two serologic HIV incidence assays. We analyzed 302 samples from 55 individuals from the RV217 cohort (Early Capture HIV ... Read more >>

AIDS Res Hum Retroviruses (AIDS research and human retroviruses)
[2020, 36(7):583-589]

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Measuring engagement in HIV care: Measurement invariance in three racial/ethnic patient groups.

John A Sauceda, Nadra E Lisha, Samantha E Dilworth, Mallory O Johnson, Katerina A Christopoulos, Troy Wood, Kimberly A Koester, W Christopher Mathews, Richard D Moore, Sonia Napravnik, Kenneth H Mayer, Heidi M Crane, Rob J Fredericksen, Michael J Mugavero, Torsten B Neilands,

Objective: The objective of the study was to evaluate a novel measure of HIV care engagement in a large sample of non-Latino White, Latino, and African American patients. The Index of Engagement in HIV care (the Index) measures the degree to which a patient feels engaged/disengaged from HIV care. However, ... Read more >>

Health Psychol (Health psychology : official journal of the Division of Health Psychology, American Psychological Association)
[2020, 39(7):622-631]

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Weight gain among treatment-naïve persons with HIV starting integrase inhibitors compared to non-nucleoside reverse transcriptase inhibitors or protease inhibitors in a large observational cohort in the United States and Canada.

Kassem Bourgi, Cathy A Jenkins, Peter F Rebeiro, Frank Palella, Richard D Moore, Keri N Altoff, John Gill, Charles S Rabkin, Stephen J Gange, Michael A Horberg, Joseph Margolick, Jun Li, Cherise Wong, Amanda Willig, Viviane D Lima, Heidi Crane, Jennifer Thorne, Michael Silverberg, Gregory Kirk, William C Mathews, Timothy R Sterling, Jordan Lake, John R Koethe, ,

INTRODUCTION:Weight gain following antiretroviral therapy (ART) initiation is common, potentially predisposing some persons with HIV (PWH) to cardio-metabolic disease. We assessed relationships between ART drug class and weight change among treatment-naïve PWH initiating ART in the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). METHODS:Adult, treatment-naïve PWH in ... Read more >>

J Int AIDS Soc (Journal of the International AIDS Society)
[2020, 23(4):e25484]

Cited: 5 times

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Racial disparities in clinician responses to patient emotions.

Jenny Park, Mary Catherine Beach, Dingfen Han, Richard D Moore, P Todd Korthuis, Somnath Saha,

<h4>Objective</h4>In a previous study of patients newly enrolled in HIV care, we observed that clinicians were less likely to address emotional issues expressed by African-American patients compared to whites. We sought to verify and expand these findings in a larger group of patients established in HIV care.<h4>Methods</h4>We used VR-CoDES to ... Read more >>

Patient Educ Couns (Patient education and counseling)
[2020, 103(9):1736-1744]

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Antiretroviral drug class and anaemia risk in the current treatment era among people living with HIV in the USA: a clinical cohort study.

Barbara N Harding, Bridget M Whitney, Robin M Nance, Heidi M Crane, Greer Burkholder, Richard D Moore, W Christopher Mathews, Joseph J Eron, Peter W Hunt, Paul Volberding, Benigno Rodriguez, Kenneth Mayer, Michael S Saag, Mari M Kitahata, Susan R Heckbert, Joseph A C Delaney,

OBJECTIVE:Anaemia is common among people living with HIV (PLWH) and has been associated with certain, often older, antiretroviral medications. Information on current antiretroviral therapy (ART) and anaemia is limited. The objective was to compare the associations between anaemia incidence or haemoglobin change with core ART classes in the current ART ... Read more >>

BMJ Open (BMJ open)
[2020, 10(3):e031487]

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