Full Text Journal Articles by
Author Riccardo Garruto Campanile

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Rectosigmoid resection during Visceral-Peritoneal Debulking (VPD) in patients with stage IIIC-IV ovarian cancer: morbidity of gynecologic oncology vs. colorectal team.

Roberto Tozzi, Gaetano Valenti, Daniele Vinti, Riccardo Garruto Campanile, Massimo Cristaldi, Federico Ferrari,

<h4>Objective</h4>This study investigates the specific morbidity of rectosigmoid resection (RSR) during Visceral-Peritoneal Debulking (VPD) in a consecutive series of patients with stage IIIC-IV ovarian cancer and compares the results of the colo-rectal vs. the gynaecologic oncology team.<h4>Methods</h4>All patients with the International Federation of Gynecology and Obstetrics (FIGO) stage IIIC-IV ovarian ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(3):e42]

Cited: 1 time

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A prospective study on the diagnostic pathway of patients with stage IIIC-IV ovarian cancer: Exploratory laparoscopy (EXL) + CT scan VS. CT scan.

Roberto Tozzi, Zoe Traill, Gaetano Valenti, Federico Ferrari, Kumar Gubbala, Riccardo Garruto Campanile,

<h4>Objective</h4>To compare the diagnostic power of CT scan to a combination of exploratory laparoscopy (EXL) and CT scan in patients with stage IIIC-IV Ovarian Cancer (OC) by anatomic areas. To investigate if adding EXL to CT can reduce unnecessary laparotomy.<h4>Methods</h4>In the period 2009-2017, 350 consecutive patients with FIGO Stage IIIC-IV ... Read more >>

Gynecol Oncol (Gynecologic oncology)
[2021, 161(1):188-193]

Cited: 0 times

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Feasibility of laparoscopic diaphragmatic peritonectomy during Visceral-Peritoneal Debulking (VPD) in patients with stage IIIC-IV ovarian cancer.

Roberto Tozzi, Hooman Soleymani Majd, Riccardo Garruto Campanile, Federico Ferrari,

<h4>Objective</h4>To describe the surgical technique and evaluate the safety, feasibility and efficacy of laparoscopic diaphragmatic peritonectomy during Visceral-Peritoneal Debulking (VPD) in patients with stage IIIC-IV ovarian cancer (OC).<h4>Methods</h4>This report is part of a Service Evaluation Protocol (Trust number 3267) on laparoscopy in patients with OC following neo-adjuvant chemotherapy. Between April ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2020, 31(5):e71]

Cited: 2 times

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The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells.

Zhiyuan Hu, Mara Artibani, Abdulkhaliq Alsaadi, Nina Wietek, Matteo Morotti, Tingyan Shi, Zhe Zhong, Laura Santana Gonzalez, Salma El-Sahhar, Mohammad KaramiNejadRanjbar, Garry Mallett, Yun Feng, Kenta Masuda, Yiyan Zheng, Kay Chong, Stephen Damato, Sunanda Dhar, Leticia Campo, Riccardo Garruto Campanile, Hooman Soleymani Majd, Vikram Rai, David Maldonado-Perez, Stephanie Jones, Vincenzo Cerundolo, Tatjana Sauka-Spengler, Christopher Yau, Ahmed Ashour Ahmed,

The inter-differentiation between cell states promotes cancer cell survival under stress and fosters non-genetic heterogeneity (NGH). NGH is, therefore, a surrogate of tumor resilience but its quantification is confounded by genetic heterogeneity. Here we show that NGH in serous ovarian cancer (SOC) can be accurately measured when informed by the molecular ... Read more >>

Cancer Cell (Cancer cell)
[2020, 37(2):226-242.e7]

Cited: 20 times

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The repertoire of serous ovarian cancer non-genetic heterogeneity revealed by single-cell sequencing of normal fallopian tube epithelial cells

Zhiyuan Hu, Mara Artibani, Abdulkhaliq Alsaadi, Nina Wietek, Matteo Morotti, Laura Santana Gonzalez, Salma El-Sahhar, Mohammad KaramiNejadRanjbar, Garry Mallett, Tingyan Shi, Kenta Masuda, Yiyan Zheng, Kay Chong, Stephen Damato, Sunanda Dhar, Riccardo Garruto Campanile, Hooman Soleymani majd, Vincenzo Cerundolo, Tatjana Sauka-Spengler, Christopher Yau, Ahmed Ahmed,

<h4>Summary</h4> The inter-differentiation between cell states promotes cancer cell survival under stress and fosters non-genetic heterogeneity (NGH). NGH is, therefore, a surrogate of tumor resilience but its quantification is confounded by genetic heterogeneity. Here we show that NGH can be accurately measured when informed by the molecular signatures of the ... Read more >>

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Tozzi classification of diaphragmatic surgery in patients with stage IIIC-IV ovarian cancer based on surgical findings and complexity.

Roberto Tozzi, Federico Ferrari, Joost Nieuwstad, Riccardo Garruto Campanile, Hooman Soleymani Majd,

<h4>Objective</h4>To introduce a systematic classification of diaphragmatic surgery in patients with ovarian cancer based on disease spread and surgical complexity.<h4>Methods</h4>For all consecutive patients who underwent diaphragmatic surgery during Visceral-Peritoneal debulking (VPD) in the period 2009-2017, we extracted: initial surgical finding, extent of liver mobilization and type of procedure. Combining these ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2020, 31(2):e14]

Cited: 3 times

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Diagnostic flow-chart to identify bowel involvement in patients with stage IIIC-IV ovarian cancer: Can laparoscopy improve the accuracy of CT scan?

Roberto Tozzi, Zoe Traill, Riccardo Garruto Campanile, Yakup Kilic, Ahmet Baysal, Raffaella Giannice, Matteo Morotti, Hooman Soleymani Majd, Gaetano Valenti,

<h4>Objective</h4>This study investigates the diagnostic power of CT scan combined with exploratory laparoscopy (EXL) at identifying large bowel involvement in patients with stage IIIC-IV primary Epithelial Ovarian Cancer (EOC) by comparing with the macroscopic surgical findings at laparotomy.<h4>Methods</h4>All patients with FIGO Stage IIIC-IV EOC who had Visceral Peritoneal Debulking (VPD) ... Read more >>

Gynecol Oncol (Gynecologic oncology)
[2019, 155(2):207-212]

Cited: 0 times

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Morbidity of multiple bowel resection compared to single bowel resection after debulking surgery for ovarian cancer.

Roberto Tozzi, Jvan Casarin, Ahmet Baysal, Ciro Pinelli, Luka Matak, Nahid Ghanbarzadeh, Moiad Alazzam, Riccardo Garruto-Campanile, Hooman Soleymani Majd, Yakup Kilic, Matteo Morotti,

<h4>Objectives</h4>To assess the impact of multiple bowel resections on postoperative outcomes in stage IIIC-IV ovarian cancer (OC).<h4>Methods</h4>From the Oxford OC database we retrieved consecutive patients who underwent bowel resection between January 2009 and November 2017. Patients were divided into two groups: single bowel resection (SBR) and MBR (‚Č•2 bowel resections). ... Read more >>

Eur J Obstet Gynecol Reprod Biol (European journal of obstetrics, gynecology, and reproductive biology)
[2019, 240:215-219]

Cited: 1 time

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Concomitant Laparoscopic and Thoracoscopic Resection of Recurrent High-Grade Ovarian Cancer.

Roberto Tozzi, Jvan Casarin, Elizabeth Belcher, Riccardo Garruto Campanile, Lamiese Ismail, Hooman Soleymani Majd, Matteo Morotti, Marcello Desgro,

STUDY OBJECTIVE:To describe the first case of combined endoscopic management of a thoracic and abdominal recurrence of ovarian cancer. DESIGN:An instructive video showing the combined thoracic and abdominal surgical procedure. SETTING:Department of Gynecological Oncology, Churchill Hospital, Oxford University, UK. PATIENTS:A 64-year-old woman undergoing endoscopic treatment for a third recurrence of ... Read more >>

J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2018, 25(7):1148]

Cited: 0 times

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Morbidity and reversal rate of ileostomy after bowel resection during Visceral-Peritoneal Debulking (VPD) in patients with stage IIIC-IV ovarian cancer.

Roberto Tozzi, Jvan Casarin, Riccardo Garruto-Campanile, Hooman Soleymani Majd, Matteo Morotti,

To investigate the morbidity of diverting loop ileostomy (DLI) performed during Visceral Peritoneal Debulking (VPD) for stage IIIC-IV ovarian cancer and to report the rate, timing, and morbidity of DLI reversal.We retrieved the data of all consecutive patients who underwent sigmoid-rectum resection (SRR) followed by DLI. Morbidity was defined as ... Read more >>

Gynecol Oncol (Gynecologic oncology)
[2018, 148(1):74-78]

Cited: 4 times

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En-bloc resection of the pelvis (EnBRP) in patients with stage IIIC-IV ovarian cancer: A 10 steps standardised technique. Surgical and survival outcomes of primary vs. interval surgery.

Roberto Tozzi, Kieran Hardern, Kumar Gubbala, Riccardo Garruto Campanile, Hooman Soleymani Majd,

<h4>Objective</h4>In this study we describe the technique of the En-bloc resection of the pelvis (EnBRP) in 10 standardised and reproducible steps, whereby all pelvic organs, except the bladder, are removed together with the peritoneum. In addition, we compare the surgical and survival outcomes of patients who underwent upfront vs. interval ... Read more >>

Gynecol Oncol (Gynecologic oncology)
[2017, 144(3):564-570]

Cited: 2 times

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Porta hepatis peritonectomy and hepato-celiac lymphadenectomy in patients with stage IIIC-IV ovarian cancer: Diagnostic pathway, surgical technique and outcomes.

Roberto Tozzi, Zoe Traill, Riccardo Garruto Campanile, Federico Ferrari, Hooman Soleymani Majd, Joost Nieuwstad, Kieran Hardern, Kumar Gubbala,

<h4>Objective</h4>To report the surgical technique of ovarian cancer resection at the porta hepatis (PH) and hepato-celiac lymph nodes (HCL). To assess surgical and survival outcomes. Define the accuracy of an integrated diagnostic pathway.<h4>Methods</h4>Patients with FIGO stage IIIC-IV ovarian cancer that underwent Visceral-Peritoneal Debulking (VPD). Data of patients with disease at ... Read more >>

Gynecol Oncol (Gynecologic oncology)
[2016, 143(1):35-39]

Cited: 8 times

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Interval Laparoscopic En-Bloc Resection of the Pelvis (L-EnBRP) in patients with stage IIIC-IV ovarian cancer: Description of the technique and surgical outcomes.

Roberto Tozzi, Kumar Gubbala, Hooman Soleymani Majd, Riccardo Garruto Campanile,

<h4>Objective</h4>To describe the technique and evaluate the feasibility, efficacy and morbidity of the Laparoscopic En-Bloc Resection of the Pelvis (L-EnBRP) during Visceral-Peritoneal Debulking (VPD) at time of interval surgery.<h4>Methods</h4>This report is part of a prospective non randomized study (service evaluation protocol) on the feasibility and safety of laparoscopy in patients ... Read more >>

Gynecol Oncol (Gynecologic oncology)
[2016, 142(3):477-483]

Cited: 5 times

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Diaphragmatic peritonectomy vs. full thickness resection with pleurectomy during Visceral-Peritoneal Debulking (VPD) in 100 consecutive patients with stage IIIC-IV ovarian cancer: A surgical-histological analysis.

Hooman Soleymani Majd, Federico Ferrari, Sanjiv Manek, Kumar Gubbala, Riccardo Garruto Campanile, Kieran Hardern, Roberto Tozzi,

<h4>Objective</h4>To compare the surgical and histological outcomes of diaphragmatic peritonectomy vs. full thickness resection with pleurectomy during Visceral-Peritoneal Debulking.<h4>Methods</h4>Service evaluation protocol (Trust number 3265). All patients with stage IIIC-IV ovarian cancer who had diaphragmatic surgery between April 2009 and November 2013 were included. Clinical notes and histology reports were reviewed. ... Read more >>

Gynecol Oncol (Gynecologic oncology)
[2016, 140(3):430-435]

Cited: 11 times

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Latest developments and techniques in gynaecological oncology surgery.

Hooman Soleymani Majd, Federico Ferrari, Kumar Gubbala, Riccardo Garruto Campanile, Roberto Tozzi,

<h4>Purpose of review</h4>To highlight the advances and the data published in the field of gynaecological oncology surgery in the last few years. The review includes not only newly introduced surgical techniques but also data that consolidate recent developments.<h4>Recent findings</h4>Ultimate data on the use of laparoscopy in the treatment of gynaecologic ... Read more >>

Curr Opin Obstet Gynecol (Current opinion in obstetrics & gynecology)
[2015, 27(4):291-296]

Cited: 6 times

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Neo-adjuvant chemotherapy does not increase the rate of complete resection and does not significantly reduce the morbidity of Visceral-Peritoneal Debulking (VPD) in patients with stage IIIC-IV ovarian cancer.

Roberto Tozzi, Raffaella Giannice, Stefano Cianci, Sarah Tardino, Riccardo Garruto Campanile, Kumar Gubbala, Giorgio Fachechi, Federico Ferrari, Igor Martinek, Hooman Soleymani Majd,

<h4>Objective</h4>To measure the efficacy and the safety of Visceral-Peritoneal Debulking (VPD) in patients with stage IIIC-IV ovarian cancer and to compare the outcomes before and after chemotherapy.<h4>Methods</h4>Between 2008 and 2013, 200 consecutive patients were offered VPD for stage IIIC/IV ovarian cancer. Exclusion criteria were: metastases in the lungs or 3 ... Read more >>

Gynecol Oncol (Gynecologic oncology)
[2015, 138(2):252-258]

Cited: 18 times

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