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Author Remy Couderc

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Two different composite markers predict severity and threshold dose in peanut allergy.

Nathalie Cottel, Sarah Saf, Melisande Bourgoin-Heck, Nathalie Lambert, Flore Amat, Pascal Poncet, Helene Senechal, Rémy Couderc, Jocelyne Just, Yannick Chantran,

BACKGROUND:Safe and cost-effective biological surrogate markers to evaluate the severity and threshold dose of peanut allergy (PA) reactions during an oral food challenge (OFC) are lacking. OBJECTIVE:To evaluate biological markers associated with the severity and threshold dose of allergic reaction during OFC in a population of children with PA. METHODS:Demographic ... Read more >>

J Allergy Clin Immunol Pract (The journal of allergy and clinical immunology. In practice)
[2020, :]

Cited: 0 times

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Performance criteria for the verification of IgE and tryptase assay methods: recommendations from the AllergoBioNet network.

Anne Sarrat, Rémy Couderc, Marie-Alexandra Alyanakian, Pol-André Apoil, Céline Beauvillain, Lionel Chollet, Pascale Chrétien, Arnaud Cirée, Benoît Cypriani, Erwan Dumontet, Bertrand Evrard, Lorna Garnier, Angélique Grenier, Valérie Guérin, Caroline Hémont, Anthony Léon, Delphine Mariotte, Pascale Nicaise-Roland, Martine Pernollet, Stéphanie Rogeau, Thierry Tabary, Béatrice Uring-Lambert, Mylène Vivinus, Joana Vitte,

Accreditation of an in vitro diagnostic assay according to the NF/EN/ISO 15189 standard requires to analyze its technical performance before implementation for routine use, and annually when reviewing effectiveness of quality controls. Performance is evaluated through repeatability, intermediate fidelity, accuracy and uncertainty of measurement. The coefficients of variation (CV) of ... Read more >>

Ann Biol Clin (Paris) (Annales de biologie clinique)
[2020, 78(3):329-342]

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Pollen/Fruit Syndrome: Clinical Relevance of the Cypress Pollen Allergenic Gibberellin-Regulated Protein.

Hélène Sénéchal, Sanaz Keykhosravi, Rémy Couderc, Marie Ange Selva, Youcef Shahali, Tomoyasu Aizawa, Jean Marc Busnel, Rihane Arif, Inna Mercier, Nhan Pham-Thi, Denis André Charpin, Pascal Poncet,

A pollen/food-associated syndrome (PFAS) has been described between peach and cypress pollen. Cross-reactive allergens were characterized which belong to the Gibberellin-regulated protein (GRP) family, BP14 in cypress pollen and Pru p 7 in peach. GRP are small cationic protein with anti-microbial properties. A patient suffering from a peach/cypress syndrome was ... Read more >>

(Allergy, asthma & immunology research)
[2019, 11(1):143-151]

Cited: 1 time

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Blood lipid tests in 2017.

Rémy Couderc, Marianne Antar, Dominique Bonnefont-Rousselot, Jean-Louis Paul, Patrice Therond,

Strong epidemiological evidence supports a causal relationship between dyslipidemia and atherosclerotic cardio-vascular disease, which remains the leading cause of death and morbidity worldwide. A lipid profile (total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides) is recommended at the initial evaluation for the assessment of the cardio-vascular risk. A commentary of the lipid profile ... Read more >>

Ann. Biol. Clin. (Paris) (Annales de biologie clinique)
[2017, 75(6):646-652]

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The IL-4 rs2070874 polymorphism may be associated with the severity of recurrent viral-induced wheeze.

Flore Amat, Malek Louha, Marta Benet, Tamazoust Guiddir, Mélisande Bourgoin-Heck, Philippe Saint-Pierre, Colombe Paluel-Marmont, Cécile Fontaine, Nathalie Lambert, Rémy Couderc, Juan-Ramon Gonzalez, Jocelyne Just,

Childhood recurrent wheezing and consequently asthma corresponds to various phenotypes. Our aim was to link genetic variants of asthma candidate genes to the phenotypes of early onset wheezing.We included very young consecutive children presenting with recurrent wheezing who had been evaluated for the severity of wheezing, associated atopic comorbidities, and ... Read more >>

Pediatr. Pulmonol. (Pediatric pulmonology)
[2017, 52(11):1435-1442]

Cited: 1 time

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Single-Step Rapid Diagnosis of Dopamine and Serotonin Metabolism Disorders.

Aurélien Lo, Pierre Guibal, Diane Doummar, Diana Rodriguez, Jean-Yves Hautem, Rémy Couderc, Thierry Billette De Villemeur, Emmanuel Roze, Pierre Chaminade, Fathi Moussa,

Early diagnosis of dopamine and serotonin metabolic defects is of importance notably because of the availability of therapeutic strategies able to prevent the associated progressive brain dysfunction. The diagnosis of these diseases relies on the determination of monoamine metabolites and pterins in cerebrospinal fluid (CSF). Current methods involve at least ... Read more >>

(ACS omega)
[2017, 2(9):5962-5972]

Cited: 1 time

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Prognostic impact of blood and urinary angiogenic factor levels at diagnosis and during treatment in patients with osteosarcoma: a prospective study.

Marie-Dominique Tabone, Laurence Brugières, Sophie Piperno-Neumann, Marie-Ange Selva, Perrine Marec-Bérard, Hélène Pacquement, Cyril Lervat, Nadège Corradini, Jean-Claude Gentet, Rémy Couderc, Aurélie Chevance, Céline Mahier-Ait Oukhatar, Natacha Entz-Werle, Jean-Yves Blay, Marie-Cecile Le Deley,

Angiogenesis is essential for the progression and metastatic spread of solid tumours. Expression of vascular endothelial growth factor (VEGF) has been linked to poor survival among osteosarcoma patients but the clinical relevance of monitoring blood and urine angiogenic factors is uncertain. The aim of this study was to determine the ... Read more >>

BMC Cancer (BMC cancer)
[2017, 17(1):419]

Cited: 1 time

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A new allergen family involved in pollen food-associated syndrome: Snakin/gibberellin-regulated proteins.

Hélène Sénéchal, Jiří Šantrůček, Magdalena Melčová, Petr Svoboda, Jarmila Zídková, Denis Charpin, Laurence Guilloux, Youcef Shahali, Marie-Ange Selva, Rémy Couderc, Tomoyasu Aizawa, Pascal Poncet,

J. Allergy Clin. Immunol. (The Journal of allergy and clinical immunology)
[2018, 141(1):411-414.e4]

Cited: 5 times

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Neutrophilic Steroid-Refractory Recurrent Wheeze and Eosinophilic Steroid-Refractory Asthma in Children.

Tamazoust Guiddir, Philippe Saint-Pierre, Elsa Purenne-Denis, Nathalie Lambert, Yacine Laoudi, Rémy Couderc, Rahelé Gouvis-Echraghi, Flore Amat, Jocelyne Just,

Little is known about inflammatory pathways of severe recurrent wheeze in preschool children and severe asthma in children.The aim of the Severe Asthma Molecular Phenotype cohort was to characterize phenotypes of severe recurrent wheeze and severe asthma during childhood in terms of triggers (allergic or not), involved cells (eosinophil or ... Read more >>

J Allergy Clin Immunol Pract (The journal of allergy and clinical immunology. In practice)
[2017, 5(5):1351-1361.e2]

Cited: 10 times

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Heterogeneity of lung disease associated with NK2 homeobox 1 mutations.

Elodie Nattes, Stephanie Lejeune, Ania Carsin, Raphael Borie, Isabelle Gibertini, Juan Balinotti, Nadia Nathan, Sylvain Marchand-Adam, Caroline Thumerelle, Brigitte Fauroux, Emmanuelle Bosdure, Veronique Houdouin, Celine Delestrain, MaleK Louha, Remy Couderc, Alix De Becdelievre, Pascale Fanen, Benoit Funalot, Bruno Crestani, Antoine Deschildre, Jean-Christophe Dubus, Ralph Epaud,

We retrospectively studied the clinical presentation, treatment modalities and outcome in 16 patients with heterozygous NKX2-1 mutation associated with chronic lung disease. Twelve different NKX2-1 mutations, including 4 novel mutations, were identified in the 16 patients. Nine patients presented with brain-lung-thyroid syndrome, 3 had neurological and lung symptoms and 4 ... Read more >>

Respir Med (Respiratory medicine)
[2017, 129:16-23]

Cited: 7 times

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A rare large mutation involving two exons of the SP-B gene in an infant with severe respiratory distress.

Şahin Takcı, Deniz Anuk-İnce, Malek Louha, Remy Couderc, Nursen Çakar, Reşit Doğan Köseoğlu, Ömer Ateş,

Takcı Ş, Anuk-İnce D, Louha M, Couderc R, Çakar N, Köseoğlu RD, Ateş Ö. A rare large mutation involving two exons of the SP-B gene in an infant with severe respiratory distress. Turk J Pediatr 2017; 59: 483-486. Hereditary surfactant protein-B (SP-B) deficiency is a rare autosomal recessive disease of ... Read more >>

Turk. J. Pediatr. (The Turkish journal of pediatrics)
[2017, 59(4):483-486]

Cited: 0 times

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Early polysensitization is associated with allergic multimorbidity in PARIS birth cohort infants.

Stephan Gabet, Jocelyne Just, Rémy Couderc, Jean Bousquet, Nathalie Seta, Isabelle Momas,

BACKGROUND:Profiles of allergic sensitization are poorly documented in infancy. Relations between early sensitization and allergic morbidity need to be clarified. METHODS:This study dealt with children involved in the Pollution and Asthma Risk: an Infant Study (PARIS), a population-based prospective birth cohort. Allergic sensitization to twelve food and four inhalant allergens ... Read more >>

Pediatr Allergy Immunol (Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology)
[2016, 27(8):831-837]

Cited: 18 times

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Urtica dioica pollen allergy: Clinical, biological, and allergomics analysis.

Angelica Tiotiu, Andrea Brazdova, Cyril Longé, Patrice Gallet, Martine Morisset, Virginie Leduc, Christiane Hilger, Cédric Broussard, Rémy Couderc, Jean-Pierre Sutra, Hélène Sénéchal, Pascal Poncet,

The most emblematic members of Urticaceae at allergic risk level are wall pellitories (Parietaria), whereas nettle (Urtica) pollen is considered as poorly allergenic. No allergen from nettle pollen has yet been characterized, whereas 4 are listed for Parietaria pollen by the International Union of Immunological Societies. Clinical and biological profiles ... Read more >>

Ann. Allergy Asthma Immunol. (Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology)
[2016, 117(5):527-534]

Cited: 2 times

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Allergic sensitisation in early childhood: Patterns and related factors in PARIS birth cohort.

Stephan Gabet, Jocelyne Just, Rémy Couderc, Nathalie Seta, Isabelle Momas,

Allergic sensitisation is poorly documented in infants. This study aims to provide new insights into allergic sensitisation patterns and related factors in infancy.This study concerns 1860 infants involved in the Pollution and Asthma Risk: an Infant Study (PARIS) population-based birth cohort who had a standardised health examination when 18 months ... Read more >>

Int J Hyg Environ Health (International journal of hygiene and environmental health)
[2016, 219(8):792-800]

Cited: 7 times

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Early-onset atopic dermatitis in children: which are the phenotypes at risk of asthma? Results from the ORCA cohort.

Flore Amat, Philippe Saint-Pierre, Emmanuelle Bourrat, Ariane Nemni, Rémy Couderc, Emmanuelle Boutmy-Deslandes, Fatiha Sahraoui, Isabelle Pansé, Martine Bagot, Sébastien Foueré, Jocelyne Just,

Atopic dermatitis (AD) is known to predate asthma and other atopic disorders described under the term "atopic march". However, this classic sequence is not always present and only a few studies have addressed children at risk of developing asthma. The objective of this study is to define early-onset AD phenotypes ... Read more >>

PLoS One (PloS one)
[2015, 10(6):e0131369]

Cited: 17 times

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The Arginine/ADMA Ratio Is Related to the Prevention of Atherosclerotic Plaques in Hypercholesterolemic Rabbits When Giving a Combined Therapy with Atorvastatine and Arginine.

Saskia J H Brinkmann, Elisabeth A Wörner, Nikki Buijs, Milan Richir, Luc Cynober, Paul A M van Leeuwen, Rémy Couderc,

Supplementation with arginine in combination with atorvastatin is more efficient in reducing the size of an atherosclerotic plaque than treatment with a statin or arginine alone in homozygous Watanabe heritable hyperlipidemic (WHHL) rabbits. We evaluated the mechanism behind this feature by exploring the role of the arginine/asymmetric dimethylarginine (ADMA) ratio, ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2015, 16(6):12230-12242]

Cited: 6 times

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In vitro anti-inflammatory effects of citrulline on peritoneal macrophages in Zucker diabetic fatty rats.

Charlotte Breuillard, Sandra Bonhomme, Rémy Couderc, Luc Cynober, Jean-Pascal De Bandt,

In type 2 diabetes (T2D) macrophage dysfunction increases susceptibility to infection and mortality. This may result from the associated decreased plasma concentration of arginine, an amino acid that plays an important role in immunity. In vitro, increasing arginine availability leads to an improvement in macrophage function; however, arginine supplementation in ... Read more >>

Br. J. Nutr. (The British journal of nutrition)
[2015, 113(1):120-124]

Cited: 10 times

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Pediatric clinical chemistry: why is it different?

Rémy Couderc, Anne Vassault,

Clin. Biochem. (Clinical biochemistry)
[2014, 47(9):747-748]

Cited: 0 times

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Determinants of allergic rhinitis in young children with asthma.

Lise Moussu, Philippe Saint-Pierre, Virginie Panayotopoulos, Rémy Couderc, Flore Amat, Jocelyne Just,

BACKGROUND: In the preschool period, allergic rhinitis (AR) is infrequent and thus under-diagnosed. However, recent works have highlighted the occurrence of AR in toddlers although the causes of AR in this young population remain unknown. The objective of this study was to identify determinants of AR in young children with ... Read more >>

PLoS One (PloS one)
[2014, 9(5):e97236]

Cited: 5 times

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Discovery of a large deletion of KAL1 in 2 deaf brothers.

Sandrine Marlin, Sandra Chantot-Bastaraud, Albert David, Natalie Loundon, Laurence Jonard, Marie-France Portnoï, Crystel Bonnet, Malek Louha, Souad Gherbi, Eréa Noël Garabedian, Remy Couderc, Françoise Denoyelle,

OBJECTIVES: Kallmann syndrome (KS) usually combines an anosmia and a hypogonadotrophic hypogonadism. Hearing impairment was described in a few cases of KS. Our objective is to describe an unusual presentation of KS in 2 cases and to explore the pattern of inheritance in this family. PATIENTS: Two brothers presented with ... Read more >>

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2013, 34(9):1590-1594]

Cited: 3 times

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Survival of an infant with homozygous surfactant protein C (SFTPC) mutation.

Zeynep Arıkan-Ayyıldız, Sule Caglayan-Sozmen, Sakine Isık, Robin Deterding, Megan K Dishop, Remy Couderc, Ralph Epaud, Malek Louha, Nevin Uzuner,

Lung diseases caused by surfactant protein C (SFTPC) mutations are inherited as autosomal traits with variable penetrance and severity or as sporadic disease caused by a de novo mutation on one allele. Here, we report the case of a child surviving with a homozygous surfactant protein C mutation after aggressive ... Read more >>

Pediatr. Pulmonol. (Pediatric pulmonology)
[2014, 49(3):E112-5]

Cited: 5 times

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[Recommendations for the evaluation and follow-up of the continuous quality improvement].

S Maurellet-Evrard, A Daunizeau, ,

Continual improvement of the quality in a medical laboratory is based on the implementation of tools for systematically evaluate the quality management system and its ability to meet the objectives defined. Monitoring through audit and management review, addressing complaints and nonconformities and performing client satisfaction survey are the key for ... Read more >>

Ann. Biol. Clin. (Paris) (Annales de biologie clinique)
[2013, 71 Spec No 1:147-176]

Cited: 0 times

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[Recommendations for the preparation of the quality manual].

A Vassault, ,

A quality manual includes the quality policy as established by the management of the medical laboratory, the objectives and indicators to control the quality management system. This manual describes the quality management system and the structure of the documentation used, with reference to supporting documents and technical procedures. It is ... Read more >>

Ann. Biol. Clin. (Paris) (Annales de biologie clinique)
[2013, 71 Spec No 1:59-78]

Cited: 0 times

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[Recommendations for the control of purchasing procedures].

A Szymanowicz, ,

The main relevant and useful process purchase choice of equipments and supplies as well as supplier evaluation are presented. Documents to develop to meet the accreditation standard ISO/FDIS 15189-2012 are listed. This article is intended to assist the biologist in his approach to mandatory certification. ... Read more >>

Ann. Biol. Clin. (Paris) (Annales de biologie clinique)
[2013, 71 Spec No 1:275-299]

Cited: 0 times

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[Evaluation of the quality management system according to the standard EN ISO 15 189: 2012. Proposition for a greed].

A Vassault, ,

This article gives a greed for evaluation of the application in medical laboratory according to requirements of the standard EN ISO 15189 : 2012. This is to allow the responsible of the laboratory to check the requirements of this standard to be applied. ... Read more >>

Ann. Biol. Clin. (Paris) (Annales de biologie clinique)
[2013, 71 Spec No 1:177-187]

Cited: 0 times

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