Full Text Journal Articles by
Author Raymond Rector

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A descriptive evaluation of causes of death in venovenous extracorporeal membrane oxygenation.

Sagar B Dave, Kristopher B Deatrick, Samuel M Galvagno, Michael A Mazzeffi, David J Kaczorowski, Ronson J Madathil, Raymond Rector, Ali Tabatabai, Daniel J Haase, Daniel Herr, Thomas M Scalea, Jay Menaker,

Veno-venous extracorporeal membrane oxygenation (VV ECMO) has become an important support modality for patients with acute respiratory failure refractory to optimal medical therapy, such as low tidal volume mechanical ventilator support, early paralytic infusion, and early prone positioning. The objective of this cohort study was to investigate the causes and ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211035938]

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Intraoperative Management of Adult Patients on Extracorporeal Membrane Oxygenation: An Expert Consensus Statement From the Society of Cardiovascular Anesthesiologists-Part I, Technical Aspects of Extracorporeal Membrane Oxygenation.

Michael A Mazzeffi, Vidya K Rao, Jeffrey Dodd-O, Jose Mauricio Del Rio, Antonio Hernandez, Mabel Chung, Amit Bardia, Rebecca M Bauer, Joseph S Meltzer, Sree Satyapriya, Raymond Rector, James G Ramsay, Jacob Gutsche,

Extracorporeal membrane oxygenation (ECMO) is used to support patients with refractory cardiopulmonary failure. Given ECMO's increased use in adults and the fact that many ECMO patients are cared for by anesthesiologists, the Society of Cardiovascular Anesthesiologists ECMO working group created an expert consensus statement that is intended to help anesthesiologists ... Read more >>

Anesth Analg (Anesthesia and analgesia)
[2021, :]

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Intraoperative Management of Adult Patients on Extracorporeal Membrane Oxygenation: An Expert Consensus Statement From the Society of Cardiovascular Anesthesiologists-Part II, Intraoperative Management and Troubleshooting.

Michael A Mazzeffi, Vidya K Rao, Jeffrey Dodd-O, Jose Mauricio Del Rio, Antonio Hernandez, Mabel Chung, Amit Bardia, Rebecca M Bauer, Joseph S Meltzer, Sree Satyapriya, Raymond Rector, James G Ramsay, Jacob Gutsche,

In the second part of the Society of Cardiovascular Anesthesiologists Extracorporeal Membrane Oxygenation (ECMO) working group expert consensus statement, venoarterial (VA) and venovenous (VV) ECMO management and troubleshooting in the operating room are discussed. Expert consensus statements are provided about intraoperative monitoring, anesthetic drug dosing, and management of intraoperative problems ... Read more >>

Anesth Analg (Anesthesia and analgesia)
[2021, :]

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A Dedicated Veno-Venous Extracorporeal Membrane Oxygenation Unit during a Respiratory Pandemic: Lessons Learned from COVID-19 Part II: Clinical Management.

Aakash Shah, Sagar Dave, Samuel Galvagno, Kristen George, Ashley R Menne, Daniel J Haase, Brian McCormick, Raymond Rector, Siamak Dahi, Ronson J Madathil, Kristopher B Deatrick, Mehrdad Ghoreishi, James S Gammie, David J Kaczorowski, Thomas M Scalea, Jay Menaker, Daniel Herr, Ali Tabatabai, Eric Krause,

(1) Background: COVID-19 acute respiratory distress syndrome (CARDS) has several distinctions from traditional acute respiratory distress syndrome (ARDS); however, patients with refractory respiratory failure may still benefit from veno-venous extracorporeal membrane oxygenation (VV-ECMO) support. We report our challenges caring for CARDS patients on VV-ECMO and alterations to traditional management strategies. ... Read more >>

Membranes (Basel) (Membranes)
[2021, 11(5):]

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A Dedicated Veno-Venous Extracorporeal Membrane Oxygenation Unit during a Respiratory Pandemic: Lessons Learned from COVID-19 Part I: System Planning and Care Teams.

Sagar Dave, Aakash Shah, Samuel Galvagno, Kristen George, Ashley R Menne, Daniel J Haase, Brian McCormick, Raymond Rector, Siamak Dahi, Ronson J Madathil, Kristopher B Deatrick, Mehrdad Ghoreishi, James S Gammie, David J Kaczorowski, Thomas M Scalea, Jay Menaker, Daniel Herr, Eric Krause, Ali Tabatabai,

<h4>Background</h4>The most critically ill patients with coronavirus disease 2019 (COVID-19) may require advanced support modalities, such as veno-venous extracorporeal membrane oxygenation (VV-ECMO). A systematic, methodical approach to a respiratory pandemic on a state and institutional level is critical.<h4>Methods</h4>We conducted retrospective review of our institutional response to the COVID-19 pandemic, focusing ... Read more >>

Membranes (Basel) (Membranes)
[2021, 11(4):]

Cited: 1 time

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Neurologic Outcomes After Extracorporeal Cardiopulmonary Resuscitation: Recent Experience at a Single High-Volume Center.

Jamie E Podell, Eric M Krause, Raymond Rector, Mubariz Hassan, Ashwin Reddi, Matthew N Jaffa, Nicholas A Morris, Daniel L Herr, Gunjan Y Parikh,

Extracorporeal cardiopulmonary resuscitation (ECPR)-veno-arterial extracorporeal membrane oxygenation (ECMO) for refractory cardiac arrest-has grown rapidly, but its widespread adoption has been limited by frequent neurologic complications. With individual centers developing best practices, utilization may be increasing with an uncertain effect on outcomes. This study describes the recent ECPR experience at the ... Read more >>

ASAIO J (ASAIO journal (American Society for Artificial Internal Organs : 1992))
[2021, :]

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Clinical Outcomes of Pregnant and Postpartum Extracorporeal Membrane Oxygenation Patients.

Allison S Lankford, Jonathan H Chow, Amanda M Jackson, Marianne Wallis, Samuel M Galvagno, Andrew M Malinow, Ozhan M Turan, Jay A Menaker, Sarah D Crimmins, Raymond Rector, David Kaczorowski, Bartley Griffith, Zachary Kon, Daniel Herr, Michael A Mazzeffi,

<h4>Background</h4>The use of extracorporeal membrane oxygenation (ECMO) as a rescue therapy for cardiopulmonary failure is expanding in critical care medicine. In this case series, we describe the clinical outcomes of 21 consecutive pregnant or postpartum patients that required venovenous (VV) or venoarterial (VA) ECMO. Our objective was to characterize maternal ... Read more >>

Anesth Analg (Anesthesia and analgesia)
[2021, 132(3):777-787]

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A Retrospective Study of Infection in Patients Requiring Extracorporeal Membrane Oxygenation Support.

Megan T Quintana, Michael Mazzeffi, Samuel M Galvagno, Danny Herrera, Gregory P Boyajian, Nicole M Hays, David Kaczorowski, Ronson J Madathil, Raymond P Rector, Ali Tabatabai, Daniel Herr, Joseph Rabin,

<h4>Background</h4>Healthcare-associated infections (HAIs) in critically ill patients are a serious public health problem. Extracorporeal membrane oxygenation (ECMO) has been used increasingly for patients with severe cardiac or respiratory failure, but it may increase HAI risk. The goal of our study was to characterize HAIs in ECMO patients at an ECMO ... Read more >>

Ann Thorac Surg (The Annals of thoracic surgery)
[2021, 112(4):1168-1175]

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Platelet factor-4 concentration in adult veno-arterial ECMO patients.

Michael Mazzeffi, Madeline Clark, Alison Grazioli, Colleen Dugan, Raymond Rector, Heidi Dalton, Ronson Madathil, Jay Menaker, Daniel Herr, Kenichi Tanaka,

<h4>Background</h4>Heparin induced thrombocytopenia (HIT) is reported at a variable rate in extracorporeal membrane oxygenation (ECMO) patients. A critical factor impacting platelet factor-4 (PF4)-heparin antibody formation is plasma PF4 concentration. We hypothesized that PF4 concentration would be increased during veno-arterial (VA) ECMO.<h4>Methods</h4>Plasma PF4 concentration was measured during the first 5 ECMO ... Read more >>

Perfusion (Perfusion)
[2021, 36(7):688-693]

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Extracorporeal Membrane Oxygenation for COVID-19.

Zachary Sanford, Ronson J Madathil, Kristopher B Deatrick, Ali Tabatabai, Jay Menaker, Samuel M Galvagno, Michael A Mazzeffi, Joseph Rabin, Mehrdad Ghoreishi, Raymond Rector, Daniel L Herr, David J Kaczorowski,

Innovations (Phila) (Innovations (Philadelphia, Pa.))
[2020, 15(4):306-313]

Cited: 0 times

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Von Willebrand Factor Concentrate Administration for Acquired Von Willebrand Syndrome- Related Bleeding During Adult Extracorporeal Membrane Oxygenation.

Michael Mazzeffi, Allison Bathula, Ali Tabatabai, Jay Menaker, David Kaczorowski, Ronson Madathil, Samuel Galvagno, Chetan Pasrija, Raymond Rector, Kenichi Tanaka, Daniel Herr,

<h4>Objective</h4>To review the use of Von Willebrand Factor (VWF) concentrate for treatment of acquired Von Willebrand syndrome (VWS)-related bleeding in adult extracorporeal membrane oxygenation (ECMO) patients and determine if it was associated with improved VWF laboratory parameters.<h4>Design</h4>Retrospective observational cohort study.<h4>Setting</h4>Tertiary care academic medical center.<h4>Participants</h4>Adult ECMO patients who received VWF concentrate ... Read more >>

J Cardiothorac Vasc Anesth (Journal of cardiothoracic and vascular anesthesia)
[2021, 35(3):882-887]

Cited: 1 time

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Early Decompressive Laparotomy for Intra-Abdominal Hypertension Following Initiation of Venovenous Extracorporeal Membrane Oxygenation.

Francesca M Boulos, Chetan Pasrija, Laura DiChiacchio, Michael Rouse, Maxwell Raithel, Kristen Mackowick, Raymond Rector, Michael A Mazzeffi, Bartley P Griffith, Jose J Diaz, Zachary N Kon, Kristopher B Deatrick,

Patients supported with venovenous extracorporeal membrane oxygenation are at risk for intra-abdominal hypertension and abdominal compartment syndrome. Flow through the return cannula may be compromised in these patients, resulting in inadequate support and end-organ malperfusion. Early decompressive laparotomy can mitigate these complications and potentially improve outcomes. Here we review a ... Read more >>

ASAIO J (ASAIO journal (American Society for Artificial Internal Organs : 1992))
[2020, 66(5):520-523]

Cited: 2 times

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Carbogen for Apnea Testing During the Brain Death Declaration Process in Subjects on Extracorporeal Membrane Oxygenation.

Maria Madden, Penny Andrews, Raymond Rector, Jay Menaker, Nader Habashi,

<h4>Background</h4>The use of extracorporeal membrane oxygenation (ECMO) in adult patients continues to increase. Suspicion of brain death while on ECMO creates a conundrum. The American Academy of Neurology states that apnea testing is a critical component of the process to declare brain death. However, there is a paucity of literature ... Read more >>

Respir Care (Respiratory care)
[2020, 65(1):75-81]

Cited: 3 times

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High-efficiency, high-flux in-line hemofiltration using a high blood flow extracorporeal circuit.

Alison Grazioli, Sanjeev R Shah, Joseph Rabin, Rashmikant Shah, Ronson J Madathil, Joshua D King, Laura DiChiacchio, Raymond P Rector, Kristopher B Deatrick, Zhongjun J Wu, Daniel L Herr,

The ability of current renal replacement therapy modalities to achieve rapid solute removal is limited by membrane surface area and blood flow rate. Extracorporeal membrane oxygenation offers high blood flow and hemodynamic support that may be harnessed to overcome limitations in traditional renal replacement therapy. Using an extracorporeal membrane oxygenation ... Read more >>

Perfusion (Perfusion)
[2020, 35(4):351-355]

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Pilot study evaluating a non-titrating, weight-based anticoagulation scheme for patients on veno-venous extracorporeal membrane oxygenation.

Kristopher B Deatrick, Samuel M Galvagno, Michael A Mazzeffi, David J Kaczoroswki, Daniel L Herr, Raymond Rector, Eric Hochberg, Ronald P Rabinowitz, Thomas M Scalea, Jay Menaker,

<h4>Objective</h4>There is no universally accepted algorithm for anticoagulation in patients on veno-venous extracorporeal membrane oxygenation. The purpose of this pilot study was to compare a non-titrating weight-based heparin infusion to that of a standard titration algorithm.<h4>Methods</h4>We performed a prospective randomized non-blinded study of patients: Arm 1-standard practice of titrating heparin ... Read more >>

Perfusion (Perfusion)
[2020, 35(1):13-18]

Cited: 3 times

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Ambulation With Femoral Arterial Cannulation Can Be Safely Performed on Venoarterial Extracorporeal Membrane Oxygenation.

Chetan Pasrija, Kristen M Mackowick, Maxwell Raithel, Douglas Tran, Francesca M Boulos, Kristopher B Deatrick, Michael A Mazzeffi, Raymond Rector, Si M Pham, Bartley P Griffith, Daniel L Herr, Zachary N Kon,

<h4>Background</h4>Venoarterial extracorporeal membrane oxygenation (VA-ECMO) support can be associated with significant deconditioning due to the requirement for strict bedrest as a result of femoral arterial cannulation. To address this issue, we evaluated our experience with ambulation in patients with peripheral femoral cannulation for VA-ECMO.<h4>Methods</h4>All patients that were peripherally cannulated for ... Read more >>

Ann Thorac Surg (The Annals of thoracic surgery)
[2019, 107(5):1389-1394]

Cited: 5 times

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Veno-Venous Extracorporeal Membrane Oxygenation (VV ECMO) for Acute Respiratory Failure Following Injury: Outcomes in a High-Volume Adult Trauma Center with a Dedicated Unit for VV ECMO.

Jay Menaker, Ronald B Tesoriero, Ali Tabatabai, Ronald P Rabinowitz, Christopher Cornachione, Terence Lonergan, Katelyn Dolly, Raymond Rector, James V O'Connor, Deborah M Stein, Thomas M Scalea,

<h4>Introduction</h4>The use of veno-venous extracorporeal membrane oxygenation (VV ECMO) has increased over the past decade. The purpose of this study was to evaluate outcomes in adult trauma patients requiring VV ECMO.<h4>Methods</h4>Data were collected on adult trauma patients admitted between January 1, 2015, and November 1, 2016. Demographics, injury-specific data, ECMO ... Read more >>

World J Surg (World journal of surgery)
[2018, 42(8):2398-2403]

Cited: 6 times

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The authors reply.

C L Wells, Jenny Forrester, Joshua Vogel, Raymond Rector, Ali Tabatabai, Daniel Herr,

Crit Care Med (Critical care medicine)
[2018, 46(4):e346]

Cited: 0 times

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Bleeding, Thrombosis, and Transfusion With Two Heparin Anticoagulation Protocols in Venoarterial ECMO Patients.

Michael A Mazzeffi, Kenichi Tanaka, Alia Roberts, Raymond Rector, Jay Menaker, Zachary Kon, Kristopher B Deatrick, David Kaczorowski, Bartley Griffith, Daniel Herr,

<h4>Objective</h4>To compare the incidence of bleeding and thrombosis between adult venoarterial (VA) extracorporeal membrane oxygenation (ECMO) patients managed with an activated clotting time (ACT)-guided heparin anticoagulation protocol and activated partial thromboplastin time (aPTT) protocol.<h4>Design</h4>Retrospective cohort study.<h4>Setting</h4>Tertiary care, academic medical center.<h4>Participants</h4>Consecutive adult VA ECMO patients during a 6-year period.<h4>Interventions</h4>None.<h4>Measurements and main ... Read more >>

J Cardiothorac Vasc Anesth (Journal of cardiothoracic and vascular anesthesia)
[2019, 33(5):1216-1220]

Cited: 10 times

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Safety and Feasibility of Early Physical Therapy for Patients on Extracorporeal Membrane Oxygenator: University of Maryland Medical Center Experience.

Chris L Wells, Jenny Forrester, Joshua Vogel, Raymond Rector, Ali Tabatabai, Daniel Herr,

OBJECTIVES:To examine the feasibility and safety of mobilizing patients while on extracorporeal membranous oxygenation support. DESIGN:Retrospective cohort study. SETTING:Medical and Surgical ICUs in a large tertiary care hospital in the United States. PATIENTS:Adults supported on extracorporeal membranous oxygenation from January 2014 to December 2015. MEASUREMENTS AND MAIN RESULTS:We reviewed the ... Read more >>

Crit Care Med (Critical care medicine)
[2018, 46(1):53-59]

Cited: 17 times

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Incidence of Cannula-Associated Deep Vein Thrombosis After Veno-Venous Extracorporeal Membrane Oxygenation.

Jay Menaker, Ali Tabatabai, Raymond Rector, Katelyn Dolly, Joseph Kufera, Eugenia Lee, Zachary Kon, Pablo Sanchez, Si Pham, Daniel L Herr, Michael Mazzeffi, Ronald P Rabinowitz, James V O'Connor, Deborah M Stein, Thomas M Scalea,

Limited literature regarding the incidence of cannula-associated deep vein thrombosis (CaDVT) after veno-venous extracorporeal membrane oxygenation (VV ECMO) exists. The purpose of this study was to identify the incidence of post decannulation CaDVT and identify any associated risk factors. Forty-eight patients were admitted between August 2014 and January 2016 to ... Read more >>

ASAIO J (ASAIO journal (American Society for Artificial Internal Organs : 1992))
[2017, 63(5):588-591]

Cited: 15 times

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The lung rescue unit-Does a dedicated intensive care unit for venovenous extracorporeal membrane oxygenation improve survival to discharge?

Jay Menaker, Katelyn Dolly, Raymond Rector, Joseph Kufera, Eugenia E Lee, Ali Tabatabai, Ronald P Rabinowitz, Zachary N Kon, Pablo Sanchez, Si Pham, Daniel L Herr, James V O'Connor, Deborah M Stein, Thomas M Scalea,

<h4>Background</h4>The use of venovenous extra corporeal membrane oxygenation (VV ECMO) for acute respiratory failure (ARF)/acute respiratory (ARDS) has increased since 2009. Specialized units for patients requiring VV ECMO are not standard and patients are often cohorted with other critically ill patients. The purpose of this study was to report the ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2017, 83(3):438-442]

Cited: 9 times

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The HAT Score-A Simple Risk Stratification Score for Coagulopathic Bleeding During Adult Extracorporeal Membrane Oxygenation.

Terence Lonergan, Daniel Herr, Zachary Kon, Jay Menaker, Raymond Rector, Kenichi Tanaka, Michael Mazzeffi,

<h4>Objective</h4>The study objective was to create an adult extracorporeal membrane oxygenation (ECMO) coagulopathic bleeding risk score.<h4>Design</h4>Secondary analysis was performed on an existing retrospective cohort. Pre-ECMO variables were tested for association with coagulopathic bleeding, and those with the strongest association were included in a multivariable model. Using this model, a risk ... Read more >>

J Cardiothorac Vasc Anesth (Journal of cardiothoracic and vascular anesthesia)
[2017, 31(3):863-868]

Cited: 1 time

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Outcomes of extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest in adult cardiac surgery patients.

Michael A Mazzeffi, Pablo G Sanchez, Daniel Herr, Eric Krause, Charles F Evans, Raymond Rector, Brian McCormick, Si Pham, Bradley Taylor, Bartley Griffith, Zachary N Kon,

<h4>Background</h4>The role of extracorporeal cardiopulmonary resuscitation (ECPR) in adult cardiac surgery patients with refractory cardiac arrest is uncertain. We hypothesized that ECPR would be associated with better than expected outcomes in this group of patients.<h4>Methods</h4>We conducted a single-center retrospective cohort study of adult cardiac surgery patients who underwent ECPR for ... Read more >>

J Thorac Cardiovasc Surg (The Journal of thoracic and cardiovascular surgery)
[2016, 152(4):1133-1139]

Cited: 13 times

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Long-Term Venovenous Extracorporeal Membrane Oxygenation Support for Acute Respiratory Distress Syndrome.

Zachary N Kon, Siamak Dahi, Charles F Evans, Kimberly A Byrnes, Gregory J Bittle, Brody Wehman, Raymond P Rector, Brian M McCormick, Daniel L Herr, Pablo G Sanchez, Si M Pham, Bartley P Griffith,

<h4>Background</h4>Given substantial advances in venovenous extracorporeal membrane oxygenation (ECMO) technology, long-term support is increasingly feasible. Although the benefits of short-term ECMO as a bridge to recovery in acute respiratory distress syndrome (ARDS) are well described, the utility and outcomes of long-term support remain unclear.<h4>Methods</h4>Patients requiring ECMO for ARDS between January ... Read more >>

Ann Thorac Surg (The Annals of thoracic surgery)
[2015, 100(6):2059-2063]

Cited: 12 times

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