Full Text Journal Articles by
Author Ravish Sachar

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Directional atherectomy before paclitaxel coated balloon angioplasty in complex femoropopliteal disease: The VIVA REALITY study.

Krishna J Rocha-Singh, Ravish Sachar, Brian G DeRubertis, Claus C A Nolte-Ernsting, John G Winscott, Prakash Krishnan, Eric C Scott, Lawrence A Garcia, Jean-Luc Baeriswyl, Gary Ansel, Kenneth Rosenfield, Thomas Zeller, ,

<h4>Background</h4>Drug coated balloon (DCB) angioplasty significantly reduces reintervention rates in patients with symptomatic femoropopliteal peripheral artery disease (PAD). However, stand-alone DCB use in long, severely calcified lesions is frequently associated with vessel recoil and/or high-grade dissections necessitating provisional stent implantation.<h4>Objectives</h4>Assess the safety and effectiveness of a vessel preparation strategy with ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2021, 98(3):549-558]

Cited: 0 times

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1-Year Results From the RANGER II SFA Randomized Trial of the Ranger Drug-Coated Balloon.

Ravish Sachar, Yoshimitsu Soga, Mohammad M Ansari, Amane Kozuki, Louis Lopez, Marianne Brodmann, Herman Schroë, Vijay S Ramanath, Juan Diaz-Cartelle, Thomas Zeller, ,

<h4>Objectives</h4>This study sought to evaluate the safety and effectiveness of the Ranger drug-coated balloon (DCB) (paclitaxel dose density 2 μg/mm<sup>2</sup>) for treating superficial femoral artery or proximal popliteal artery lesions.<h4>Background</h4>Paclitaxel-coated balloon treatment prevents reinterventions, but dose and coating characteristics differ among balloons and necessitate discrete confirmation of safety and effectiveness.<h4>Methods</h4>Patients with ... Read more >>

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2021, 14(10):1123-1133]

Cited: 0 times

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Response by Schneider et al to Letter Regarding Article, "Treatment Effect of Drug-Coated Balloons Is Durable to 3 Years in the Femoropopliteal Arteries: Long-Term Results of the IN.PACT SFA Randomized Trial".

Peter A Schneider, John R Laird, Gunnar Tepe, Marianne Brodmann, Thomas Zeller, Dierk Scheinert, Christopher Metzger, Antonio Micari, Ravish Sachar, Michael R Jaff, Hong Wang, Melissa S Hasenbank, Prakash Krishnan, ,

Circ Cardiovasc Interv (Circulation. Cardiovascular interventions)
[2018, 11(6):e006699]

Cited: 1 time

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Treatment Effect of Drug-Coated Balloons Is Durable to 3 Years in the Femoropopliteal Arteries: Long-Term Results of the IN.PACT SFA Randomized Trial.

Peter A Schneider, John R Laird, Gunnar Tepe, Marianne Brodmann, Thomas Zeller, Dierk Scheinert, Christopher Metzger, Antonio Micari, Ravish Sachar, Michael R Jaff, Hong Wang, Melissa S Hasenbank, Prakash Krishnan, ,

BACKGROUND:Randomized controlled trials have reported favorable 1-year outcomes with drug-coated balloons (DCBs) for the treatment of symptomatic peripheral arterial disease when compared with standard percutaneous transluminal angioplasty (PTA). Evidence remains limited on the durability of the treatment effect with DCBs in the longer term. METHODS AND RESULTS:IN.PACT SFA is a ... Read more >>

Circ Cardiovasc Interv (Circulation. Cardiovascular interventions)
[2018, 11(1):e005891]

Cited: 40 times

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Stellarex Drug-Coated Balloon for Treatment of Femoropopliteal Disease: Twelve-Month Outcomes From the Randomized ILLUMENATE Pivotal and Pharmacokinetic Studies.

Prakash Krishnan, Peter Faries, Khusrow Niazi, Ash Jain, Ravish Sachar, William B Bachinsky, Joseph Cardenas, Martin Werner, Marianne Brodmann, J A Mustapha, Carlos Mena-Hurtado, Michael R Jaff, Andrew H Holden, Sean P Lyden,

<h4>Background</h4>Drug-coated balloons (DCBs) are a predominant revascularization therapy for symptomatic femoropopliteal artery disease. Because of the differences in excipients, paclitaxel dose, and coating morphologies, varying clinical outcomes have been observed with different DCBs. We report the results of 2 studies investigating the pharmacokinetic and clinical outcomes of a new DCB ... Read more >>

Circulation (Circulation)
[2017, 136(12):1102-1113]

Cited: 39 times

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Nine-month results of the REFORM study: a prospective, single-arm, multicenter clinical study of the safety and effectiveness of the Formula™ balloon-expandable stent for treatment of renal artery stenosis.

Robert M Bersin, Gary Ansel, Anthony Rizzo, H Bob Smouse, Shantanu Sinha, Ravish Sachar, Rajesh Dave, Barry S Weinstock, Robert Feldman, Gary S Roubin,

<h4>Objectives</h4>To evaluate the 9-month safety and effectiveness outcomes of the Formula™ balloon-expandable renal stent (Cook Medical, Bloomington, IN) for the treatment of atherosclerotic renal artery stenosis (RAS) following suboptimal angioplasty.<h4>Background</h4>Atherosclerotic RAS can cause hypertension and ischemic nephropathy. When clinically indicated, an interventional approach with renal angioplasty and stent implantation is ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2013, 82(2):266-273]

Cited: 13 times

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The transradial approach for carotid artery stenting.

Nicholena Etxegoien, Diana Rhyne, Sasko Kedev, Ravish Sachar, Tift Mann,

<h4>Background</h4>Carotid artery stenting (CAS) is an alternative to carotid endarterectomy (CEA) for revascularization of the internal carotid artery (ICA). CAS from the femoral approach may be problematic due to peripheral vascular disease, anatomical variations of the aortic arch, and access site complications. The purpose of this study was to evaluate ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2012, 80(7):1081-1087]

Cited: 21 times

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Strategies for multivessel revascularization in patients with diabetes.

Michael E Farkouh, Michael Domanski, Lynn A Sleeper, Flora S Siami, George Dangas, Michael Mack, May Yang, David J Cohen, Yves Rosenberg, Scott D Solomon, Akshay S Desai, Bernard J Gersh, Elizabeth A Magnuson, Alexandra Lansky, Robin Boineau, Jesse Weinberger, Krishnan Ramanathan, J Eduardo Sousa, Jamie Rankin, Balram Bhargava, John Buse, Whady Hueb, Craig R Smith, Victoria Muratov, Sameer Bansilal, Spencer King, Michel Bertrand, Valentin Fuster, ,

<h4>Background</h4>In some randomized trials comparing revascularization strategies for patients with diabetes, coronary-artery bypass grafting (CABG) has had a better outcome than percutaneous coronary intervention (PCI). We sought to discover whether aggressive medical therapy and the use of drug-eluting stents could alter the revascularization approach for patients with diabetes and multivessel ... Read more >>

N Engl J Med (The New England journal of medicine)
[2012, 367(25):2375-2384]

Cited: 587 times

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Impact of diabetes mellitus on outcome of patients undergoing carotid artery stenting: insights from a single center registry.

Hitinder S Gurm, Vivek Rajagopal, Ravish Sachar, Alex Abou-Chebl, Samir R Kapadia, Chris Bajzer, Jay S Yadav,

<h4>Objective</h4>To evaluate the impact of diabetic status on outcome of patients undergoing carotid artery stenting (CAS).<h4>Background</h4>Diabetes has been demonstrated to be a strong predictor of adverse outcome in patients undergoing coronary revascularization. Its significance in predicting outcome of patients undergoing carotid interventions has not been ascertained.<h4>Methods</h4>We evaluated the short-term outcomes ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2007, 69(4):541-545]

Cited: 6 times

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Transradial approach for carotid artery stenting: a feasibility study.

Jessica Folmar, Ravish Sachar, Tift Mann,

<h4>Background</h4>Carotid artery stenting (CAS) has become accepted as an alternative to carotid endarterectomy for revascularization of the internal carotid artery (ICA) among high risk patients. CAS from the femoral approach can be problematic due to access site complications as well as technical difficulties related to peripheral vascular disease (PVD) and/or ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2007, 69(3):355-361]

Cited: 26 times

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Symptomatic patients have similar outcomes compared with asymptomatic patients after carotid artery stenting with emboli protection.

Michael H Yen, David S Lee, Samir Kapadia, Ravish Sachar, Deepak L Bhatt, Christopher T Bajzer, Jay S Yadav,

In a single-center cohort of 174 consecutive patients, we sought to evaluate whether the use of emboli protection devices (EPDs) results in equivalent rates of adverse events in symptomatic and asymptomatic patients after carotid artery stenting (CAS) with EPDs. Death or stroke occurred in 3.3% in the symptomatic group and ... Read more >>

Am J Cardiol (The American journal of cardiology)
[2005, 95(2):297-300]

Cited: 12 times

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Evaluating the optimal activated clotting time during carotid artery stenting.

Jacqueline Saw, Christopher Bajzer, Ivan P Casserly, Emilio Exaire, Cameron Haery, Ravish Sachar, David Lee, Alex Abou-Chebl, Jay S Yadav,

Carotid artery stenting is an alternative to carotid endarterectomy for patients at high risk for surgery for carotid artery stenosis. Although unfractionated heparin is routinely used, there are no published data evaluating the optimal activated clotting time during carotid stenting. In a retrospective analysis of 605 patients who underwent carotid ... Read more >>

Am J Cardiol (The American journal of cardiology)
[2006, 97(11):1657-1660]

Cited: 11 times

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Intravascular ultrasound evidence of angiographically silent progression in coronary atherosclerosis predicts long-term morbidity and mortality after cardiac transplantation.

E Murat Tuzcu, Samir R Kapadia, Ravish Sachar, Khaled M Ziada, Timothy D Crowe, Jingyuan Feng, William A Magyar, Robert E Hobbs, Randall C Starling, James B Young, Patrick McCarthy, Steven E Nissen,

<h4>Objectives</h4>The aim of this study was to determine whether angiographically silent early coronary intimal thickening could predict long-term morbidity and mortality.<h4>Background</h4>Although intravascular ultrasound (IVUS) is widely used to detect early transplant coronary disease, its prognostic significance has not been well defined.<h4>Methods</h4>The study cohort consisted of 143 patients who underwent early ... Read more >>

J Am Coll Cardiol (Journal of the American College of Cardiology)
[2005, 45(9):1538-1542]

Cited: 134 times

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Utility of IVUS-guided transaccess catheter in the treatment of long chronic total occlusion of the superficial femoral artery.

Ivan P Casserly, Ravish Sachar, Christopher Bajzer, Jay S Yadav,

Failure to reenter the true lumen distal to an occlusion is the most frequent cause of failure of the technique of subintimal angioplasty. We report the utility of an IVUS-guided TransAccess catheter in overcoming this problem in the treatment of two patients with long chronic total occlusion of the superficial ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2004, 62(2):237-243]

Cited: 17 times

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Severe bilateral carotid stenosis: the impact of ipsilateral stenting on Doppler-defined contralateral stenosis.

Ravish Sachar, Jay S Yadav, Marco Roffi, Leslie Cho, Joel P Reginelli, Alex Aböu-Chebl, Deepak L Bhatt, Christopher T Bajzer,

<h4>Objectives</h4>The study examined the effect of carotid stenting (CS) on contralateral carotid Doppler-defined degree of stenosis.<h4>Background</h4>Patients with carotid disease are frequently referred for carotid revascularization (carotid endarterectomy [CEA] or CS) based on the results of carotid duplex studies. Although a drop in flow velocities in the contralateral carotid has been ... Read more >>

J Am Coll Cardiol (Journal of the American College of Cardiology)
[2004, 43(8):1358-1362]

Cited: 10 times

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Drug-eluting stents: the beginning of the end of restenosis?

Cameron Haery, Ravish Sachar, Stephen G Ellis,

In multiple clinical trials, patients who received drug-eluting stents instead of plain stents during percutaneous coronary interventions had rates of restenosis that were lower by roughly one half to three fourths, depending on how restenosis was defined and on the population studied. These stents will likely be used more and ... Read more >>

Cleve Clin J Med (Cleveland Clinic journal of medicine)
[2004, 71(10):815-824]

Cited: 7 times

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Relation of albumin/creatinine ratio to C-reactive protein and to the metabolic syndrome.

Adrian W Messerli, Niranjan Seshadri, Gregory L Pearce, Ravish Sachar, Byron J Hoogwerf, Dennis L Sprecher,

We hypothesized that the association of high sensitivity C-reactive protein (CRP) with urinary albumin excretion (UAE) is predominately mediated through its correlation with the metabolic syndrome. Serum CRP and urine albumin:creatinine ratios (ACR) from 720 preventive cardiology patients were analyzed to estimate age- and gender-adjusted relative risk of high CRP ... Read more >>

Am J Cardiol (The American journal of cardiology)
[2003, 92(5):610-612]

Cited: 14 times

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Association between apolipoprotein E alleles and calcific valvular heart disease.

Gian M Novaro, Ravish Sachar, Gregory L Pearce, Dennis L Sprecher, Brian P Griffin,

BACKGROUND: Studies on apolipoprotein E (apoE) alleles have reported an increased risk of coronary heart disease in patients with the apoE4 allele. Given the risk factor and histological similarities between coronary and calcific valvular heart disease (aortic stenosis [AS] and mitral annular calcification [MAC]), we postulated that apoE alleles might ... Read more >>

Circulation (Circulation)
[2003, 108(15):1804-1808]

Cited: 54 times

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