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Author Ramona O Hopkins

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Transitions of Care After Critical Illness-Challenges to Recovery and Adaptive Problem Solving.

Kimberley J Haines, Elizabeth Hibbert, Nina Leggett, Leanne M Boehm, Tarli Hall, Rita N Bakhru, Anthony J Bastin, Brad W Butcher, Tammy L Eaton, Wendy Harris, Aluko A Hope, James Jackson, Annie Johnson, Janet A Kloos, Karen A Korzick, Pamela Mactavish, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Andrew Slack, Dorothy Wade, Mary Still, Giora Netzer, Ramona O Hopkins, Theodore J Iwashyna, Mark E Mikkelsen, Joanne McPeake, Carla M Sevin, ,

<h4>Objectives</h4>Investigate the challenges experienced by survivors of critical illness and their caregivers across the transitions of care from intensive care to community, and the potential problem-solving strategies used to navigate these challenges.<h4>Design</h4>Qualitative design-data generation via interviews and data analysis via the framework analysis method.<h4>Setting</h4>Patients and caregivers from three continents, identified ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(11):1923-1931]

Cited: 0 times

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Design of Clinical Trials Evaluating Sedation in Critically Ill Adults Undergoing Mechanical Ventilation: Recommendations From Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research (SCEPTER) Recommendation III.

Denham S Ward, Anthony R Absalom, Leanne M Aitken, Michele C Balas, David L Brown, Lisa Burry, Elizabeth Colantuoni, Douglas Coursin, John W Devlin, Franklin Dexter, Robert H Dworkin, Talmage D Egan, Doug Elliott, Ingrid Egerod, Pamela Flood, Gilles L Fraser, Timothy D Girard, David Gozal, Ramona O Hopkins, John Kress, Mervyn Maze, Dale M Needham, Pratik Pandharipande, Richard Riker, Daniel I Sessler, Steven L Shafer, Yahya Shehabi, Claudia Spies, Lena S Sun, Avery Tung, Richard D Urman,

<h4>Objectives</h4>Clinical trials evaluating the safety and effectiveness of sedative medication use in critically ill adults undergoing mechanical ventilation differ considerably in their methodological approach. This heterogeneity impedes the ability to compare results across studies. The Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research Recommendations convened a meeting ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(10):1684-1693]

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Evaluating the Balance Between Privacy and Access in Digital Information Sharing.

Sarah J Beesley, Alex Powell, Danielle Groat, Jorie Butler, Ramona O Hopkins, Ronen Rozenblum, Hanan Aboumatar, Allison M Butler, Jeremy Sugarman, Leslie Francis, Samuel M Brown,

<h4>Objectives</h4>Access to personal health records in an ICU by persons involved in the patient's care (referred to broadly as "family members" below) has the potential to increase engagement and reduce the negative psychologic sequelae of such hospitalizations. Currently, little is known about patient preferences for information sharing with a designated ... Read more >>

Crit Care Med (Critical care medicine)
[2021, :]

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Understanding Patients' Perceived Health After Critical Illness: Analysis of Two Prospective, Longitudinal Studies of ARDS Survivors.

Alison E Turnbull, Hongkai Ji, Victor D Dinglas, Albert W Wu, Pedro A Mendez-Tellez, Cheryl Dennison Himmelfarb, Carl B Shanholtz, Megan M Hosey, Ramona O Hopkins, Dale M Needham,

<h4>Background</h4>Perceived health is one of the strongest determinants of subjective well-being, but it has received little attention among survivors of ARDS.<h4>Research question</h4>How well do self-reported measures of physical, emotional, and social functioning predict perceived overall health (measured using the EQ-5D visual analog scale [EQ-5D-VAS]) among adult survivors of ARDS? Are ... Read more >>

Chest (Chest)
[2021, :]

Cited: 0 times

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Six-month and 12-month patient outcomes based on inflammatory subphenotypes in sepsis-associated ARDS: secondary analysis of SAILS-ALTOS trial.

Mohamed D Hashem, Ramona O Hopkins, Elizabeth Colantuoni, Victor D Dinglas, Pratik Sinha, Lisa Aronson Friedman, Peter E Morris, James C Jackson, Catherine L Hough, Carolyn S Calfee, Dale M Needham,

<h4>Background</h4>Prior acute respiratory distress syndrome (ARDS) trials have identified hypoinflammatory and hyperinflammatory subphenotypes, with distinct differences in short-term outcomes. It is unknown if such differences extend beyond 90 days or are associated with physical, mental health or cognitive outcomes.<h4>Methods</h4>568 patients in the multicentre Statins for Acutely Injured Lungs from Sepsis ... Read more >>

Thorax (Thorax)
[2021, :]

Cited: 1 time

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Association of imbalance between job workload and functional ability with return to work in ARDS survivors.

Han Su, Ramona O Hopkins, Biren B Kamdar, Susanne May, Victor D Dinglas, Kurt L Johnson, Megan Hosey, Catherine L Hough, Dale M Needham, Hilaire J Thompson,

<h4>Background</h4>Inability to return to work (RTW) is common after acute respiratory distress syndrome (ARDS). Mismatch in an individual's job workload and his or her functional ability, termed work ability imbalance, is negatively associated with RTW, but has not been evaluated in ARDS survivors.<h4>Object</h4>We examine associations between work ability imbalance at ... Read more >>

Thorax (Thorax)
[2021, :]

Cited: 0 times

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Association of Job Characteristics and Functional Impairments on Return to Work After ARDS.

Han Su, Hilaire J Thompson, Susanne May, Victor D Dinglas, Catherine L Hough, Megan M Hosey, Ramona O Hopkins, Biren B Kamdar, Dale M Needham,

<h4>Background</h4>Joblessness is common after ARDS, but related risk factors are not fully understood.<h4>Research question</h4>What is the association between survivors' pre-ARDS workload and post-ARDS functional impairment, pain, and fatigue with their return to work (RTW) status?<h4>Study design and methods</h4>The U.S. Occupational Information Network (O∗NET) was used to determine pre-ARDS workload for ... Read more >>

Chest (Chest)
[2021, 160(2):509-518]

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Bodily pain in survivors of acute respiratory distress syndrome: A 1-year longitudinal follow-up study.

Julia M Probert, Shihong Lin, Haijuan Yan, Jeannie-Marie S Leoutsakos, Victor D Dinglas, Megan M Hosey, Ann M Parker, Ramona O Hopkins, Dale M Needham, Karin J Neufeld,

<h4>Purpose</h4>Acute respiratory distress syndrome (ARDS) survivors frequently experience bodily pain during recovery after the intensive care unit. Longitudinal course, risk factors and associations with physical and neuropsychological health is lacking.<h4>Methods</h4>We collected self-reported pain using the Short Form-36 Bodily Pain (SF-36 BP) scale, normalized for sex and age (range: 0-100; higher ... Read more >>

J Psychosom Res (Journal of psychosomatic research)
[2021, 144:110418]

Cited: 0 times

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Benefits of Peer Support for Intensive Care Unit Survivors: Sharing Experiences, Care Debriefing, and Altruism.

Joanne McPeake, Theodore J Iwashyna, Leanne M Boehm, Elizabeth Hibbert, Rita N Bakhru, Anthony J Bastin, Brad W Butcher, Tammy L Eaton, Wendy Harris, Aluko A Hope, James Jackson, Annie Johnson, Janet A Kloos, Karen A Korzick, Joel Meyer, Ashley Montgomery-Yates, Mark E Mikkelsen, Andrew Slack, Dorothy Wade, Mary Still, Giora Netzer, Ramona O Hopkins, Tara Quasim, Carla M Sevin, Kimberley J Haines,

<h4>Background</h4>After critical illness, patients are often left with impairments in physical, social, emotional, and cognitive functioning. Peer support interventions have been implemented internationally to ameliorate these issues.<h4>Objective</h4>To explore what patients believed to be the key mechanisms of effectiveness of peer support programs implemented during critical care recovery.<h4>Methods</h4>In a secondary analysis ... Read more >>

Am J Crit Care (American journal of critical care : an official publication, American Association of Critical-Care Nurses)
[2021, 30(2):145-149]

Cited: 2 times

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Functional electrical stimulation in-bed cycle ergometry in mechanically ventilated patients: a multicentre randomised controlled trial.

Sue Berney, Ramona O Hopkins, Joleen Wyn Rose, Rene Koopman, Zudin Puthucheary, Amy Pastva, Ian Gordon, Elizabeth Colantuoni, Selina M Parry, Dale M Needham, Linda Denehy,

<h4>Purpose</h4>To investigate the effect of functional electrical stimulation-assisted cycle ergometry (FES-cycling) on muscle strength, cognitive impairment and related outcomes.<h4>Methods</h4>Mechanically ventilated patients aged ≥18 years with sepsis or systemic inflammatory response syndrome were randomised to either 60 min of FES-cycling <u>></u>5 days/week while in the intensive care unit (ICU) plus usual care rehabilitation ... Read more >>

Thorax (Thorax)
[2021, 76(7):656-663]

Cited: 3 times

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Prediction Models for Physical, Cognitive, and Mental Health Impairments After Critical Illness: A Systematic Review and Critical Appraisal.

Kimberley J Haines, Elizabeth Hibbert, Joanne McPeake, Brian J Anderson, Oscar Joseph Bienvenu, Adair Andrews, Nathan E Brummel, Lauren E Ferrante, Ramona O Hopkins, Catherine L Hough, James Jackson, Mark E Mikkelsen, Nina Leggett, Ashley Montgomery-Yates, Dale M Needham, Carla M Sevin, Becky Skidmore, Mary Still, Maarten van Smeden, Gary S Collins, Michael O Harhay,

<h4>Objectives</h4>Improved ability to predict impairments after critical illness could guide clinical decision-making, inform trial enrollment, and facilitate comprehensive patient recovery. A systematic review of the literature was conducted to investigate whether physical, cognitive, and mental health impairments could be predicted in adult survivors of critical illness.<h4>Data sources</h4>A systematic search of ... Read more >>

Crit Care Med (Critical care medicine)
[2020, 48(12):1871-1880]

Cited: 5 times

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Society of Critical Care Medicine's International Consensus Conference on Prediction and Identification of Long-Term Impairments After Critical Illness.

Mark E Mikkelsen, Mary Still, Brian J Anderson, O Joseph Bienvenu, Martin B Brodsky, Nathan Brummel, Brad Butcher, Alison S Clay, Hali Felt, Lauren E Ferrante, Kimberley J Haines, Michael O Harhay, Aluko A Hope, Ramona O Hopkins, Megan Hosey, Catherine Terri L Hough, James C Jackson, Annie Johnson, Babar Khan, Nazir I Lone, Pamela MacTavish, Joanne McPeake, Ashley Montgomery-Yates, Dale M Needham, Giora Netzer, Christa Schorr, Becky Skidmore, Joanna L Stollings, Reba Umberger, Adair Andrews, Theodore J Iwashyna, Carla M Sevin,

<h4>Background</h4>After critical illness, new or worsening impairments in physical, cognitive, and/or mental health function are common among patients who have survived. Who should be screened for long-term impairments, what tools to use, and when remain unclear.<h4>Objectives</h4>Provide pragmatic recommendations to clinicians caring for adult survivors of critical illness related to screening ... Read more >>

Crit Care Med (Critical care medicine)
[2020, 48(11):1670-1679]

Cited: 16 times

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Evaluating the association between unmet healthcare needs and subsequent clinical outcomes: protocol for the Addressing Post-Intensive Care Syndrome-01 (APICS-01) multicentre cohort study.

Narjes Akhlaghi, Dale M Needham, Somnath Bose, Valerie M Banner-Goodspeed, Sarah J Beesley, Victor D Dinglas, Danielle Groat, Tom Greene, Ramona O Hopkins, James Jackson, Mustafa Mir-Kasimov, Carla M Sevin, Emily Wilson, Samuel M Brown,

<h4>Introduction</h4>As short-term mortality declines for critically ill patients, a growing number of survivors face long-term physical, cognitive and/or mental health impairments. After hospital discharge, many critical illness survivors require an in-depth plan to address their healthcare needs. Early after hospital discharge, numerous survivors experience inadequate care or a mismatch between ... Read more >>

BMJ Open (BMJ open)
[2020, 10(10):e040830]

Cited: 2 times

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Day-of-Injury Computed Tomography and Longitudinal Rehabilitation Outcomes: A Comparison of the Marshall and Rotterdam Computed Tomography Scoring Methods.

Kayla M Frodsham, Joseph E Fair, R Brock Frost, Ramona O Hopkins, Erin D Bigler, Sarah Majercik, Joseph Bledsoe, David Ryser, Joel MacDonald, Ryan Barrett, Susan D Horn, David Pisani, Mark Stevens, Michael J Larson,

<h4>Objective</h4>The aim of the study was to compare the relative predictive value of Marshall Classification System and Rotterdam scores on long-term rehabilitation outcomes. This study hypothesized that Rotterdam would outperform Marshall Classification System.<h4>Design</h4>The study used an observational cohort design with a consecutive sample of 88 participants (25 females, mean age ... Read more >>

Am J Phys Med Rehabil (American journal of physical medicine & rehabilitation)
[2020, 99(9):821-829]

Cited: 1 time

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Depression and Change in Caregiver Burden Among Family Members of Intensive Care Unit Survivors.

Sarah J Beesley, Eliotte L Hirshberg, Emily L Wilson, Jorie M Butler, Thomas A Oniki, Kathryn G Kuttler, James F Orme, Ramona O Hopkins, Samuel M Brown,

<h4>Background</h4>Family members of patients in intensive care units may experience psychological distress and substantial caregiver burden.<h4>Objective</h4>To evaluate whether change in caregiver burden from intensive care unit admission to 3-month follow-up is associated with caregiver depression at 3 months.<h4>Methods</h4>Caregiver burden was assessed at enrollment and 3 months later, and caregiver depression ... Read more >>

Am J Crit Care (American journal of critical care : an official publication, American Association of Critical-Care Nurses)
[2020, 29(5):350-357]

Cited: 0 times

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Key Components of ICU Recovery Programs: What Did Patients Report Provided Benefit?

Joanne McPeake, Leanne M Boehm, Elizabeth Hibbert, Rita N Bakhru, Anthony J Bastin, Brad W Butcher, Tammy L Eaton, Wendy Harris, Aluko A Hope, James Jackson, Annie Johnson, Janet A Kloos, Karen A Korzick, Pamela MacTavish, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Andrew Slack, Dorothy Wade, Mary Still, Giora Netzer, Ramona O Hopkins, Mark E Mikkelsen, Theodore J Iwashyna, Kimberley J Haines, Carla M Sevin,

To understand from the perspective of patients who did, and did not attend ICU recovery programs, what were the most important components of successful programs and how should they be organized. Design:International, qualitative study. Setting:Fourteen hospitals in the United States, United Kingdom, and Australia. Patients:We conducted 66 semi-structured interviews with ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0088]

Cited: 7 times

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Assessment of White Matter Integrity after Pediatric Traumatic Brain Injury.

Kacie L Wright, Ramona O Hopkins, Frank E Robertson, Erin D Bigler, H Gerry Taylor, Kenneth H Rubin, Kathryn Vannatta, Terry Stancin, Keith Owen Yeates,

White matter (WM) abnormalities, such as atrophy and hyperintensities (WMH), can be accessed via magnetic resonance imaging (MRI) after pediatric traumatic brain injury (TBI). Several methods are available to classify WM abnormalities (i.e., total WM volumes and WMHs), but automated and manual volumes and clinical ratings have yet to be ... Read more >>

J Neurotrauma (Journal of neurotrauma)
[2020, 37(20):2188-2197]

Cited: 1 time

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Fatigue Symptoms During the First Year Following ARDS.

Karin J Neufeld, Jeannie-Marie S Leoutsakos, Haijuan Yan, Shihong Lin, Jeffrey S Zabinski, Victor D Dinglas, Megan M Hosey, Ann M Parker, Ramona O Hopkins, Dale M Needham,

<h4>Background</h4>Fatigue is commonly reported by ARDS survivors, but empirical data are scarce.<h4>Research question</h4>This study evaluated fatigue prevalence and associated variables in a prospective study of ARDS survivors.<h4>Study design and methods</h4>This analysis is part of the ARDSNet Long-Term Outcomes Study (ALTOS) conducted at 38 US hospitals. Using age- and sex-adjusted, time-averaged ... Read more >>

Chest (Chest)
[2020, 158(3):999-1007]

Cited: 15 times

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Persistence of patient and family experiences of critical illness.

Eliotte L Hirshberg, Jorie Butler, Morgan Francis, Francis A Davis, Doriena Lee, Fahina Tavake-Pasi, Edwin Napia, Jeanette Villalta, Valentine Mukundente, Heather Coulter, Louisa Stark, Sarah J Beesley, James F Orme, Samuel M Brown, Ramona O Hopkins,

<h4>Objective</h4>To investigate: (1) patient and family experiences with healthcare and the intensive care unit (ICU); (2) experiences during their critical illness; (3) communication and decision making during critical illness; (4) feelings about the ICU experience; (5) impact of the critical illness on their lives; and (6) concerns about their future ... Read more >>

BMJ Open (BMJ open)
[2020, 10(4):e035213]

Cited: 0 times

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Association Between Participant Contact Attempts and Reports of Being Bothered in a National, Longitudinal Cohort Study of ARDS Survivors.

Michelle N Eakin, Thomas Eckmann, Victor D Dinglas, Ayodele A Akinremi, Megan Hosey, Ramona O Hopkins, Dale M Needham,

<h4>Background</h4>Participant retention is a major challenge in clinical research, especially in studies with multiple, longitudinal research assessments. Despite the importance of retention methods, there is little empirical research on how cohort retention efforts are perceived by study participants.<h4>Research question</h4>To evaluate the association between the number of attempts undertaken to contact ... Read more >>

Chest (Chest)
[2020, 158(2):588-595]

Cited: 2 times

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Identifying Clinical Research Priorities in Adult Pulmonary and Critical Care: NHLBI Working Group Report.

Matthew W Semler, Gordon R Bernard, Shawn D Aaron, Derek C Angus, Michelle H Biros, Roy G Brower, Carolyn S Calfee, Elizabeth A Colantuoni, Niall D Ferguson, Michelle N Gong, Ramona O Hopkins, Catherine L Hough, Theodore J Iwashyna, Bruce D Levy, Thomas R Martin, Michael A Matthay, Joseph P Mizgerd, Marc Moss, Dale M Needham, Wesley H Self, Christopher W Seymour, Renee D Stapleton, B Taylor Thompson, Richard G Wunderink, Neil R Aggarwal, Lora A Reineck,

Preventing, treating, and promoting recovery from critical illness due to pulmonary disease are foundational goals of the critical care community and the National Heart, Lung, and Blood Institute. Decades of clinical research in acute respiratory distress syndrome, acute respiratory failure, pneumonia, and sepsis have yielded improvements in supportive care, which ... Read more >>

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2020, :]

Cited: 10 times

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Correction to: Screening for posttraumatic stress disorder in ARDS survivors: validation of the impact of event Scale-6 (IES-6).

Megan M Hosey, Jeannie-Marie S Leoutsakos, Ximin Li, Victor D Dinglas, O Joseph Bienvenu, Ann M Parker, Ramona O Hopkins, Dale M Needham, Karin J Neufeld,

In the publication of this article [1], there is an error in the Abstract. This has now been included in this correction article. ... Read more >>

Crit Care (Critical care (London, England))
[2020, 24(1):37]

Cited: 2 times

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Postseptic Cognitive Impairment and Expression of APOE in Peripheral Blood: The Cognition After SepsiS (CASS) Observational Pilot Study.

Samuel M Brown, Sarah J Beesley, Chris Stubben, Emily L Wilson, Angela P Presson, Colin Grissom, Colin Maguire, Matthew T Rondina, Ramona O Hopkins,

<h4>Background</h4>Cognitive impairment after sepsis is an important clinical problem. Determinants of postseptic cognitive impairment are not well understood. We thus undertook a systems biology approach to exploring a possible role for apolipoprotein E (APOE) in postseptic cognitive impairment.<h4>Design</h4>Prospective, observational cohort.<h4>Setting</h4>Intermountain Medical Center, a tertiary referral center in Utah.<h4>Patients/participants</h4>Patients with sepsis ... Read more >>

J Intensive Care Med (Journal of intensive care medicine)
[2021, 36(3):262-270]

Cited: 0 times

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Return to work after critical illness: a systematic review and meta-analysis.

Biren B Kamdar, Rajat Suri, Mary R Suchyta, Kyle F Digrande, Kyla D Sherwood, Elizabeth Colantuoni, Victor D Dinglas, Dale M Needham, Ramona O Hopkins,

BACKGROUND:Survivors of critical illness often experience poor outcomes after hospitalisation, including delayed return to work, which carries substantial economic consequences. OBJECTIVE:To conduct a systematic review and meta-analysis of return to work after critical illness. METHODS:We searched PubMed, Embase, PsycINFO, CINAHL and Cochrane Library from 1970 to February 2018. Data were ... Read more >>

Thorax (Thorax)
[2020, 75(1):17-27]

Cited: 31 times

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Impact of Critical Illness on Resource Utilization: A Comparison of Use in the Year Before and After ICU Admission.

Eliotte L Hirshberg, Emily L Wilson, Valoree Stanfield, Kathryn G Kuttler, Sarah Majercik, Sarah J Beesley, James Orme, Ramona O Hopkins, Samuel M Brown,

<h4>Objectives</h4>Increasingly, patients admitted to an ICU survive to hospital discharge; many with ongoing medical needs. The full impact of an ICU admission on an individual's resource utilization and survivorship trajectory in the United States is not clear. We sought to compare healthcare utilization among ICU survivors in each year surrounding ... Read more >>

Crit Care Med (Critical care medicine)
[2019, 47(11):1497-1504]

Cited: 3 times

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