Full Text Journal Articles by
Author Rami N Khouzam

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Complex interventions in the failing heart.

Anandbir S Bath, Joel Raja, Miguel A Maturana, Rami N Khouzam,

<h4>Purpose of review</h4>Heart failure is a complex clinical syndrome with a substantial disease burden. We aim to review the interventional aspects of management of advanced heart failure, focusing on the role of management of coronary artery disease, valvular heart disease, and mechanical circulatory support.<h4>Recent findings</h4>The patients with coronary artery disease ... Read more >>

Curr Opin Organ Transplant (Current opinion in organ transplantation)
[2021, 26(3):267-272]

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Meta-Analysis of Outcomes in Ultrasound Guided Versus Traditional Guided Vascular Access for Interventional Cardiac and Peripheral Vascular Procedures.

Abdul Aziz A Asbeutah, Akram M Asbeutah, Uzoma N Ibebuogu, Rami N Khouzam,

Am J Cardiol (The American journal of cardiology)
[2021, :]

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Chronic Systemic Inflammatory Skin Disease as a Risk Factor for Cardiovascular Disease.

David A Bulger, Sheharyar Minhas, Abdul Aziz Asbeutah, Sharif Kayali, Hamid A K Shirwany, Jay R Patel, Michael Paul Seitz, Katie Clark, Tejesh Patel, Rami N Khouzam,

Chronic systemic skin disease and cardiovascular disease are multisystem disorders which have been associated with each other for centuries. Recent research has strengthened this association, particularly in systemic inflammatory disease. Here we explore the current literature on psoriasis, hidradenitis suppurativa, lupus erythematosus, acanthosis nigricans, atopic dermatitis, and bullous pemphigoid. Psoriasis ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(5):100799]

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Challenges of Combining Opioids and P2Y12 Inhibitors in Acute Coronary Syndrome: Should the Future Be Opioid Free?

Catherine H Moore, Jack G Lukas, Brandon E Cave, Rami N Khouzam,

Morphine has been long recognized as standard of care in the treatment of acute coronary syndrome (ACS) patients; however, its safety has recently been called into question due to a drug interaction with P2Y<sub>12</sub> inhibitors. Opioids, given in combination with P2Y<sub>12</sub> inhibitors, can reduce antiplatelet effects by slowing gastrointestinal motility ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(4):100781]

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Review of Hypothermia Protocol and Timing of the Echocardiogram.

Issa Pour-Ghaz, Sheharyar Minhas, Sharif Kayali, Jay Patel, Fatima Hassan, Abdul Aziz Asbeutah, Raza Askari, Uzoma N Ibebuogu, Rami N Khouzam,

Targeted temperature management, also known as therapeutic hypothermia (TH), is recommended for out-of-hospital cardiac arrest (OHCA). Both internal or external methods of cooling can be applied. Individuals resuscitated from OHCA frequently develop postarrest myocardial dysfunction resulting in decreased cardiac output and left ventricular systolic function. This dysfunction is usually transient ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(4):100786]

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Prognostic Value of Left Ventricular Global Strain Analysis by Two-Dimensional Speckle-Tracking Echocardiography in Non-Hemodynamically Significant Intermediate Coronary Lesions.

Manolo Rubio, Kevin B Lo, Pradhum Ram, Cindy S Rubio, Michael Co, Padmini Varadarajan, Aman M Amanullah, Huu T Truong, Rami N Khouzam, Islam Abudayyeh,

Intermediate coronary lesions represent a major challenge for the invasive and noninvasive cardiologist. Left ventricular strain calculation by speckle tracking echocardiography has the capacity to analyze the motion of the cardiac tissue. This study aimed to evaluate its usefulness and prognostic significance in nonhemodynamically significant intermediate coronary lesions. We studied ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(4):100787]

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Can Radiation Dose Burden of CT Angiography be Reduced While Still Accurately Diagnosing Etiology of Acute Chest Pain?

Sherine M Sharara, Scott R Monnin, Manolo Rubio, Rami N Khouzam, Samar R Ragheb,

<h4>Background</h4>Multidetector-row computed tomography is often used as a first-line test in the diagnostic evaluation of cardiovascular diseases including aortic dissection, coronary artery disease and pulmonary embolism. This study evaluated the impact of reducing the tube potential from 120 kVp to 100 kVp in a selected group of patients presenting to ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(4):100766]

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Are Die-Hard Football or Other Sports Fans at Risk of Cardiovascular Events?

Miguel A Maturana, Elizabeth A Glover, Joel Raja, Sean R Dornbush, John Alexander, Courtland Blount, Nadim R Khouzam, Amir R Khouzam, Rami N Khouzam,

Trigger factors such as earthquakes, war, and terrorism have been shown to increase the risk of cardiovascular events in different studies. Similarly, strong emotions and psychological stress have been associated with myocardial infarction, symptomatic arrhythmias, and sudden cardiac death. Die-hard soccer, rugby, football, and baseball fans seem to be at ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(3):100743]

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Distal Transradial Access for Coronary Angiography and Interventions.

Manolo Rubio, Hamid A K Shirwany, Scott R Monnin, Rami N Khouzam,

Coronary angiography is one of the most common procedures done in the United States and in other developed countries. For decades, the femoral artery has been the most common vascular access site utilized for this procedure. However, the radial access has been gaining popularity for being a safer and yet ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(3):100714]

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Fish Oil Dilemma: Does It Increase the Risk of Ventricular Arrhythmias and Death? Can Fish Oil Kill You?

Addis Asfaw, Sheharyar Minhas, Amir R Khouzam, Nadim R Khouzam, Rami N Khouzam,

Omega-3-fatty-acids are now increasingly being used for potential beneficial anti-inflammatory effect in the treatment and management of cardiovascular disease. Eicosapentaenoic acid and Docosahexaenoic acid are 2 essential omega-3 fatty acids found predominately in fish and fish oil supplements. Despite the increased use of fish oil products for both primary and ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(3):100718]

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The Role of Colchicine in Coronary Artery Disease.

Asra Khalid Butt, Brandon Cave, Miguel Maturana, William F Towers, Rami N Khouzam,

There is increasing experimental and clinical evidence that inflammation appears to play an important role in atherosclerosis and coronary artery disease. Treatment of coronary artery disease currently involves management of cardiovascular risk factors, lipid-lowering strategies and antiplatelet medications. Inflammation seems to be central to the pathogenesis of atherosclerotic plaque development, ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(3):100690]

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Invasive Strategies for the Treatment of Pulmonary Embolism. Where Are We in 2020?

Miguel A Maturana, Michael P Seitz, Issa Pour-Ghaz, Uzoma N Ibebuogu, Rami N Khouzam,

Pulmonary Embolism (PE) is the third most common cause of cardiovascular mortality in the United States, with 60,000-100,000 deaths per year following myocardial infarction and stroke. During the past 5 years, there has been an introduction of novel interventions as a result of a renewed interest in optimizing PE management, ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(3):100650]

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Smoke and Heart Should Stay Apart: A Look at E Cigarettes and Other Alternatives to Conventional Cigarettes, and Their Impact on Cardiovascular Health.

Joel Raja, Amir Khouzam, Nadim Khouzam, Rami N Khouzam,

The leading cause of preventable death in the world is smoking; leading to 7 million deaths attributable to tobacco use per year worldwide and 480,000 deaths per year in the United States. Though the actual rates of smoking in the United States have been on the decline, the advent of ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(3):100640]

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Can Computed Fractional Flow Reserve Coronary CT Angiography (FFRCT) Offer an Accurate Noninvasive Comparison to Invasive Coronary Angiography (ICA)? "The Noninvasive CATH." A Comprehensive Review.

Joel Raja, Michael P Seitz, Neeraja Yedlapati, Rami N Khouzam,

Invasive coronary angiography (ICA) serves as a very important tool in the diagnosis of coronary artery disease (CAD) and provides information for further intervention. Fractional Flow Reserve (FFR) at the time of ICA is the gold standard to analyze the hemodynamic and physiologic significance of moderate coronary stenosis. The dawn ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(3):100642]

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Implantable Cardioverter Defibrillators and Chronic Kidney Disease.

James N Kiage, Zara Latif, Michael A Craig, Nawar Mansour, Rami N Khouzam,

Use of implantable cardioverter defibrillators (ICDs) is the treatment of choice for heart failure patients with ejection fraction <35% to prevent sudden cardiac death. Whether this benefit remains among patients with chronic kidney disease (CKD) or end stage renal disease (ESRD) is yet to be elucidated. We conducted a systematic ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(3):100639]

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Association of history of heart failure with hospital outcomes of hyperglycemic crises: Analysis from a University hospital and national cohort.

Manyoo A Agarwal, Nidhi Jain, Pradeep S B Podila, Vinithra Varadarajan, Brijesh Patel, Mahek Shah, Lohit Garg, Rami N Khouzam, Uzoma Ibebuogu, Guy L Reed, Samuel Dagogo-Jack,

<h4>Aims</h4>The impact of a history of heart failure (HF) on the outcomes of hospitalization for hyperglycemic crises (diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome) is unknown. We aimed to test the hypothesis that a history of HF has a deleterious impact on the outcomes of hospitalization for hyperglycemic crises.<h4>Methods</h4>We used two ... Read more >>

J Diabetes Complications (Journal of diabetes and its complications)
[2020, 34(1):107466]

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From Tick Bite to Heart Failure: Ehrlichial Myocarditis.

Nureddin K Almaddah, Aranyak Rawal, Devarshi Ardeshna, Kirstin Hesterberg, Shadwan Alsafwah, Rami N Khouzam, Neeraja Yedlapati,

Cardiac involvement in myocarditis induced by Human Monocytic Ehrlichiosis infection is an incredibly uncommon complication with sparsely available literature. Also, this case highlights the importance of early recognition as a first step in management. ... Read more >>

CJC Open (CJC open)
[2019, 1(6):327-329]

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Chest X-Ray to Predict Difficult Right Transradial Cardiac Catheterization Due to Vascular Tortuosity: A Retrospective Study.

Salem A Salem, Pooja S Jagadish, Devarshi Ardeshna, Rami N Khouzam, Shadwan Alsafwah, Abhinav Sharma, Dipan Uppal, Rafal Kedzierski, Nadish Garg,

Tortuous brachiocephalic artery may lead to procedural difficulties among patients undergoing right transradial cardiac catheterization. By prospectively identifying patients with this anatomic barrier, operators may choose an alternate catheterization site to avoid complications from switching midway. To assess brachiocephalic artery tortuosity, 23 patients who underwent challenging diagnostic coronary angiography by ... Read more >>

Curr Probl Cardiol (Current problems in cardiology)
[2021, 46(3):100471]

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CardioMEMS: where we are and where can we go?

Issa Pour-Ghaz, David Hana, Joel Raja, Uzoma N Ibebuogu, Rami N Khouzam,

The prevalence of heart failure (HF) has been on the rise with associated increase in hospitalizations, morbidity and mortality. These hospitalizations have led to increasingly more cost on and decreased quality of life for patients. CardioMEMS is one of the newer devices designed to help tackle this issue by allowing ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2019, 7(17):418]

Cited: 2 times

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After COACT trial-new perspectives for the management of non-ST elevation myocardial infarction: early versus late cardiac catheterization post cardiac arrest.

Miguel A Maturana, Charles F Clinton, Selene Caballero-Cummings, Brandon Cave, Amal Khan, Amit Nanda, Devarshi Ardeshna, Joel Raja, Rami N Khouzam,

Out-of-hospital cardiac arrest (OHCA) is the leading cause of death in the United States, as 90% of them are fatal per the 2018 American Heart Association statistics. As many as fifty-percent of cardiac arrest events display an initial rhythm of pulseless ventricular tachycardia (pVT) and ventricular fibrillation (VF), and of ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2019, 7(17):413]

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Intravenous cangrelor as a peri-procedural bridge with applied uses in ischemic events.

Venugopal B Bhattad, Sathvika Gaddam, Margaret A Lassiter, Pooja S Jagadish, Devarshi Ardeshna, Brandon Cave, Rami N Khouzam,

Cangrelor is a relatively new antiplatelet drug that has been approved for use as an adjunct therapy to percutaneous coronary intervention (PCI) to decrease peri-procedural myocardial infarction (MI), coronary revascularization, and stent thrombosis. Cangrelor is an adenosine triphosphate analogue with a pharmacokinetic mechanism based on a reversible, dose-dependent inhibition adenosine ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2019, 7(17):408]

Cited: 2 times

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Wearable cardioverter defibrillators: dead on arrival or chance of survival?

Pooja S Jagadish, Rami N Khouzam,

Ann Transl Med (Annals of translational medicine)
[2019, 7(17):403]

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Transcatheter aortic valve replacement with a focus on transcarotid: a review of the current literature.

Issa Pour-Ghaz, Joel Raja, Mahmoud Bayoumi, Theodore Manolukas, Rami N Khouzam, Uzoma N Ibebuogu,

Valve replacement in high-risk patients with severe aortic stenosis has undergone a huge paradigm shift in the recent years in terms of procedural details and vascular access site for patients who have poor peripheral access. Carotid artery is one of the more promising access sites which has been proven to ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2019, 7(17):420]

Cited: 3 times

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Action plan for improving cardiac rehabilitation-related outcomes in a university hospital based on a review of previous interventions.

Carol Elsakr, Leesa Wright, Pooja S Jagadish, David A Bulger, Uzoma N Ibebuogu, Rami N Khouzam,

Although referral to cardiac rehabilitation (CR) is considered the standard of care and demonstrably reduces both mortality rates and hospital admissions after cardiac events, rates of referral continue to be suboptimal. In fact, national reports reveal rates ranging from approximately 60% to 85% depending on the type of cardiac event. ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2019, 7(17):415]

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Targeting ticagrelor: a novel therapy for emergency reversal.

Brandon Cave, Aranyak Rawal, Devarshi Ardeshna, Uzoma N Ibebuogu, Chittoor B Sai-Sudhakar, Rami N Khouzam,

Newer P2Y12 inhibitors are prescribed in place of clopidogrel for patients with acute coronary syndrome (ACS) and are associated with significant bleeding risks. Currently, limited options exist for the management of life-threatening bleeding or acute reversal for patients on P2Y12 inhibitor therapy, specifically ticagrelor. Various interventions, including platelet transfusion and ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2019, 7(17):410]

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