Full Text Journal Articles by
Author R Conway

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Non-Specific Clinical Presentations are Not Prognostic and do not Anticipate Hospital Length of Stay or Resource Utilization.

Richard Conway, Declan Byrne, Deirdre O'Riordan, Bernard Silke,

<h4>Aim</h4>To investigate whether a specific (SP) or non-specific (NSP) clinical presentation, predicts prognosis and in-hospital resource utilization in emergency medical admissions.<h4>Methods</h4>We studied admissions over 5 years (2015-2019) and classified the symptom presentation as SP or NSP. The predictive capacity of the NSP category was related to 30-day in-hospital mortality with ... Read more >>

Eur J Intern Med (European journal of internal medicine)
[2021, :]

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Frequency-specific Electrocochleography and Traveling Wave Time as a Clinical Test for Menière's Disease.

Robert M Conway, Eric M Sugihara, David M Lee, Jaclyn Renker, Pedrom C Sioshansi, Seilesh C Babu,

<h4>Introduction</h4>Menière's disease is a clinical entity with no definitive objective testing. It has been hypothesized that underlying endolymphatic hydrops stiffens the basilar membrane leading to increased speed of the acoustic stimulus, therefore traveling wave velocity has been proposed as an objective test to aid in the diagnosis. The objective of ... Read more >>

Otol Neurotol (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2021, 42(2):290-293]

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Association between age at disease onset of anti-neutrophil cytoplasmic antibody-associated vasculitis and clinical presentation and short-term outcomes.

Sara Monti, Anthea Craven, Catherine Klersy, Carlomaurizio Montecucco, Roberto Caporali, Richard Watts, Peter A Merkel, Raashid Luqmani, ,

<h4>Objectives</h4>ANCA-associated vasculitis (AAV) can affect all age groups. We aimed to show that differences in disease presentation and 6 month outcome between younger- and older-onset patients are still incompletely understood.<h4>Methods</h4>We included patients enrolled in the Diagnostic and Classification Criteria for Primary Systemic Vasculitis (DCVAS) study between October 2010 and January 2017 ... Read more >>

Rheumatology (Oxford) (Rheumatology (Oxford, England))
[2021, 60(2):617-628]

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Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.

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<h4>Background</h4>Azithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatory actions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19.<h4>Methods</h4>In this randomised, controlled, open-label, adaptive platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), several possible treatments were ... Read more >>

Lancet (Lancet (London, England))
[2021, 397(10274):605-612]

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Correspondence on 'Influence of COVID-19 pandemic on decisions for the management of people with inflammatory rheumatic and musculoskeletal diseases: a survey among EULAR countries'.

Shamma Al Nokhatha, Neil MacEoin, Richard Conway,

Ann Rheum Dis (Annals of the rheumatic diseases)
[2021, :]

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Factors associated with COVID-19-related death in people with rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance physician-reported registry.

Anja Strangfeld, Martin Schäfer, Milena A Gianfrancesco, Saskia Lawson-Tovey, Jean W Liew, Lotta Ljung, Elsa F Mateus, Christophe Richez, Maria J Santos, Gabriela Schmajuk, Carlo A Scirè, Emily Sirotich, Jeffrey A Sparks, Paul Sufka, Thierry Thomas, Laura Trupin, Zachary S Wallace, Sarah Al-Adely, Javier Bachiller-Corral, Suleman Bhana, Patrice Cacoub, Loreto Carmona, Ruth Costello, Wendy Costello, Laure Gossec, Rebecca Grainger, Eric Hachulla, Rebecca Hasseli, Jonathan S Hausmann, Kimme L Hyrich, Zara Izadi, Lindsay Jacobsohn, Patricia Katz, Lianne Kearsley-Fleet, Philip C Robinson, Jinoos Yazdany, Pedro M Machado, , ,

<h4>Objectives</h4>To determine factors associated with COVID-19-related death in people with rheumatic diseases.<h4>Methods</h4>Physician-reported registry of adults with rheumatic disease and confirmed or presumptive COVID-19 (from 24 March to 1 July 2020). The primary outcome was COVID-19-related death. Age, sex, smoking status, comorbidities, rheumatic disease diagnosis, disease activity and medications were included ... Read more >>

Ann Rheum Dis (Annals of the rheumatic diseases)
[2021, :]

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Biologic Therapies for Giant Cell Arteritis.

Robert Harrington, Shamma Ahmad Al Nokhatha, Richard Conway,

Glucocorticoids have been the mainstay of treatment in giant cell arteritis (GCA) for the past 70 years. Conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs) have largely failed to show significant clinical efficacy or reduction of the glucocorticoid burden in GCA. Tocilizumab is the first biologic to make a substantial impact in ... Read more >>

Biologics (Biologics : targets & therapy)
[2021, 15:17-29]

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Validating the Matching of Patients in the Linkage of a Large Hospital System's EHR with State and National Death Databases.

Rebecca B N Conway, Matthew G Armistead, Michael J Denney, Gordon S Smith,

<h4>Background</h4>Though electronic health record (EHR) data have been linked to national and state death registries, such linkages have rarely been validated for an entire hospital system's EHR.<h4>Objectives</h4>The aim of the study is to validate West Virginia University Medicine's (WVU Medicine) linkage of its EHR to three external death registries: the ... Read more >>

Appl Clin Inform (Applied clinical informatics)
[2021, 12(1):82-89]

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Operative Repair of a Lateral Abdominal Dehiscence After External Oblique Release for Component Separation.

Kathrine A Kelly-Schuette, Joesph DeVitis, Ryan Conway, Amy Banks-Venegoni,

Am Surg (The American surgeon)
[2020, :3134820982551]

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Glycerol phenylbutyrate efficacy and safety from an open label study in pediatric patients under 2 months of age with urea cycle disorders.

Nicola Longo, George A Diaz, Uta Lichter-Konecki, Andreas Schulze, Michal Inbar-Feigenberg, Robert L Conway, Allison A Bannick, Shawn E McCandless, Roberto Zori, Bryan Hainline, Nicholas Ah Mew, Colleen Canavan, Thomas Vescio, Teresa Kok, Marty H Porter, Susan A Berry,

<h4>Background/aims</h4>Neonatal onset Urea cycle disorders (UCDs) can be life threatening with severe hyperammonemia and poor neurological outcomes. Glycerol phenylbutyrate (GPB) is safe and effective in reducing ammonia levels in patients with UCD above 2 months of age. This study assesses safety, ammonia control and pharmacokinetics (PK) of GPB in UCD ... Read more >>

Mol Genet Metab (Molecular genetics and metabolism)
[2021, 132(1):19-26]

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Is there excessive troponin testing in clinical practice? Evidence from emergency medical admissions.

Richard Conway, Declan Byrne, Seán Cournane, Deirdre O'Riordan, Seamus Coveney, Bernard Silke,

<h4>Aim</h4>To investigate whether excessive high-sensitivity cardiac troponin T (hscTnT) testing, in non-cardiac presentations, increases hospital length of stay (LOS) by driving down-stream investigations.<h4>Methods</h4>We report on all hscTnT tests in emergency medical admissions, performed over a 9-year period between 2011-2019. Troponin testing frequency in different risk cohorts was determined and related ... Read more >>

Eur J Intern Med (European journal of internal medicine)
[2020, :]

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Next Stop a Longer Life.

R Conway, A O'Farrell,

Aim A request was made to the Department of Public Health in early 2019 for some interesting statistics (funtistics) for a planned health promotion campaign encouraging public transport users to increase their physical activity levels by alighting one stop earlier and walking to their destination. For a novel presentation of ... Read more >>

Ir Med J (Irish medical journal)
[2020, 112(10):1025]

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Clinical pathways for patients with giant cell arteritis during the COVID-19 pandemic: an international perspective.

Sarah L Mackie, Elisabeth Brouwer, Richard Conway, Kornelis S M van der Geest, Puja Mehta, Susan P Mollan, Lorna Neill, Michael Putman, Philip C Robinson, Sebastian E Sattui,

Giant cell arteritis, a common primary systemic vasculitis affecting older people, presents acutely as a medical emergency and requires rapid specialist assessment and treatment to prevent irreversible vision loss. Disruption of the health-care system caused by the COVID-19 pandemic exposed weak points in clinical pathways for diagnosis and treatment of ... Read more >>

Lancet Rheumatol (The Lancet. Rheumatology)
[2021, 3(1):e71-e82]

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Treating interstitial lung disease in rheumatoid arthritis - the embers of hope.

Richard Conway, Elena Nikiphorou,

Rheumatology (Oxford) (Rheumatology (Oxford, England))
[2020, 59(12):3589-3590]

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Diabetes and liver cancer risk: A stronger effect in Whites than Blacks?

Rebecca Baqiyyah N Conway, Staci Sudenga, Donald McClain, William J Blot,

<h4>Background</h4>Both diabetes and liver cancer are overrepresented among African Americans, but limited information is available on the interrelationship of these two diseases among African Americans. We examined the association of diabetes with the incidence of liver cancer and whether this varied by participant self-reported race/ethnicity.<h4>Methods</h4>Using the Southern Community Cohort Study, ... Read more >>

J Diabetes Complications (Journal of diabetes and its complications)
[2021, 35(3):107816]

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Constipation and glycemic control.

Rebecca B N Conway, Amanda Peltier, M Kathleen Figaro,

J Diabetes Complications (Journal of diabetes and its complications)
[2021, 35(2):107799]

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Is barium esophagram enough? Comparison of esophageal motility found on barium esophagram to high resolution manometry.

Giuseppe Zambito, Robert Roether, Brittany Kern, Ryan Conway, David Scheeres, Amy Banks-Venegoni,

<h4>Background</h4>The aim of the study is to determine if barium esophagram (BE) alone is sufficient to diagnose esophageal dysmotility when compared to the gold standard, high-resolution manometry (HRM).<h4>Methods</h4>This is a retrospective review of patients that underwent laparoscopic fundoplication by two surgeons at a single institution from 10/1/2015-6/29/2019. Patients with large ... Read more >>

Am J Surg (American journal of surgery)
[2020, :]

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Racial Variation in the Relationship of Glycemic Control with Fracture Risk in Elderly Patients with Diabetes.

M Kathleen Figaro, Dustin M Long, Michael E May, Harrison Ndetan, Alan Cook, Rebecca Baqiyyah Conway,

We investigated racial variation in glycemic control (glycated hemoglobin A1c [HbA1c]) with fracture risk in geriatric patients with diabetes. Compared to an HbA1c of 7.0-7.9% [53-63 mmol/mol], HbA1c ≥9.0% [≥75 mmol/mol] was associated with increased fracture risk among Blacks and those of Unknown race only. This increase was attenuated in ... Read more >>

Diabetes Metab Syndr Obes (Diabetes, metabolic syndrome and obesity : targets and therapy)
[2020, 13:4153-4155]

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Routine testing of close contacts of confirmed COVID-19 cases - National COVID-19 Contact Management Programme, Ireland, May to August 2020.

C Carroll, R Conway, D O'Donnell, C Norton, E Hogan, M Browne, C M Buckley, P Kavanagh, J Martin, S Doyle,

<h4>Objectives</h4>The objective of this study was to inform public health practitioners who are designing, adapting and implementing testing and tracing strategies for Coronavirus disease (COVID-19) control.<h4>Study design</h4>The study design is monitoring and evaluation of a national public health protection programme.<h4>Methods</h4>All close contacts of laboratory-confirmed cases of COVID-19 identified between the ... Read more >>

Public Health (Public health)
[2021, 190:147-151]

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Giant Cell Arteritis and COVID-19: Similarities and Discriminators. A Systematic Literature Review.

Puja Mehta, Sebastian E Sattui, Kornelis S M van der Geest, Elisabeth Brouwer, Richard Conway, Michael S Putman, Philip C Robinson, Sarah L Mackie,

<h4>Objective</h4>To identify shared and distinct features of giant cell arteritis (GCA) and coronavirus disease 2019 (COVID-19) to reduce diagnostic errors that could cause delays in correct treatment.<h4>Methods</h4>Two systematic literature reviews determined the frequency of clinical features of GCA and COVID-19 in published reports. Frequencies in each disease were summarized using ... Read more >>

J Rheumatol (The Journal of rheumatology)
[2020, :]

Cited: 2 times

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Use of anti-reflux medications in infants under 1 year of age: a retrospective drug utilization study using national prescription reimbursement data.

Daniel O'Reilly, Robert Conway, Lois O'Connor, Patrick Fitzpatrick,

Non-specific symptoms such as irritability, vomiting, and back arching during the infant period are often attributed to gastroesophageal reflux. While numerous studies have shown no significant benefit to the use of acid suppressant medications in this population, these medications are frequently prescribed in response to these symptoms. Our goals were ... Read more >>

Eur J Pediatr (European journal of pediatrics)
[2020, 179(12):1963-1967]

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Lipid-Producing Ciliochoroidal Melanoma with Expression of HMG-CoA Reductase.

David Van Ly, Duo Wang, Robert Max Conway, Michael Giblin, Sharron Liang, Robyn Lukeis, Li-Anne Lim, Luke Hesson, Svetlana Cherepanoff,

Uveal melanoma (UM) is the commonest primary intraocular malignancy in adults. There is limited published data on lipid production in UM. Here, we describe the clinical, histological, immunohistochemical, and molecular findings in a ciliochoroidal melanoma with lipid production and expression of the enzyme HMG-CoA reductase. This case highlights an unusual ... Read more >>

Ocul Oncol Pathol (Ocular oncology and pathology)
[2020, 6(6):416-421]

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Allopurinol and Chronic Kidney Disease.

Richard Conway,

N Engl J Med (The New England journal of medicine)
[2020, 383(17):1689]

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Methionine adenosyltransferase I/III deficiency: Long-term follow-up and treatment of 3 adult siblings.

Allison Bannick, Sara Chase, Alyson Miner, Mary Seeterlin, Robert L Conway,

Methionine adenosyltransferase I/III deficiency, also known as Mudd's disease, is a rare inborn error of methionine metabolism. Because pathophysiological mechanisms of the disease remain poorly understood, the consequences of this disorder and the need for medical management remain uncertain; likewise, the effect of medical interventions on clinical outcomes in Mudd's ... Read more >>

Eur J Med Genet (European journal of medical genetics)
[2020, 63(12):104076]

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Perioperative cost evaluation of canal wall down mastoidectomy.

Robert M Conway, Pedrom C Sioshansi, Anthony L Howard, Seilesh C Babu,

<h4>Introduction</h4>To evaluate perioperative costs of canal wall-down (CWD) mastoidectomy as an initial surgery compared to revision surgery following initial canal wall-up (CWU) mastoidectomy.<h4>Methods</h4>This study is a retrospective chart review of adult patients who underwent CWD mastoidectomy for chronic otitis media with or without cholesteatoma at a tertiary referral center. Patients ... Read more >>

Am J Otolaryngol (American journal of otolaryngology)
[2020, 41(6):102733]

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