Full Text Journal Articles by
Author R Cartuyvels

Advertisement

Find full text journal articles






Multicenter evaluation of the FilmArray Meningitis/Encephalitis assay in a routine setting.

Karel Maelegheer, Marijke Reynders, Katelijne Floré, Jos Vanacker, Elke Vanlaere, Reinoud Cartuyvels, Marijke Raymaekers,

Introduction. The FilmArray Meningitis/Encephalitis (FA-ME) Panel (Biofire, Salt Lake City, Utah, US) enables fast and automated detection of 14 pathogens in cerebrospinal fluid (CSF).Gap statement. The performance of the FA-ME panel in a real routine setting has not yet been described and could lead to better patient management in cases ... Read more >>

J Med Microbiol (Journal of medical microbiology)
[2021, 70(10):]

Cited: 0 times

View full text PDF listing >>



The Evolution of COVID-19: A Minimal Invasive Autopsy Cohort Studying in Depth the Different COVID- 19 Disease Stages

Valentino D’Onofrio, Lotte Keulen, Annelore Vandendriessche, Jasperina Dubois, Reinoud Cartuyvels, Marie-Elena Vanden Abeele, Judith Fraussen, Patrick Vandormael, Veerle Somers, Ruth Achten, Amélie Dendooven, Ann Driessen, Lukasz Augsburg, Niels Hellings, Martin Lammens, Jan Vanrusselt, Janneke Cox,

<h4>Background: </h4> The WHO defines different COVID-19 disease stages, where pathophysiological mechanisms differ. Clinical, radiological, histological, microbiological, and immunological characteristics of different COVID-19 disease stages were evaluated. <h4>Methods: </h4> Forty-four PCR-confirmed COVID-19 patients were included in a prospective minimal invasive autopsy cohort. Patients were classified according to WHO disease classification ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

A prospective observational cohort study to identify inflammatory biomarkers for the diagnosis and prognosis of patients with sepsis

Valentino D’Onofrio, Dries Heylen, Murih Pusparum, Inge Grondman, Johan Vanwalleghem, Agnes Meersman, Reinoud Cartuyvels, Peter Messiaen, Leo AB Joosten, Mihai Netea, Dirk Valkenborg, Gökhan Ertaylan, Inge Gyssens,

<h4>Background</h4> Sepsis is a life-threatening organ dysfunction. A fast diagnosis is crucial for patient management. Proteins that are synthesized during the inflammatory response can be used as biomarkers, helping in a rapid clinical assessment or an early diagnosis of infection. The aim of this study was to identify biomarkers of ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Audit of empirical antibiotic therapy for sepsis and the impact of early multidisciplinary consultation on patient outcomes.

Valentino D'Onofrio, Agnes Meersman, Koen Magerman, Luc Waumans, Karlijn van Halem, Janneke A Cox, Jeroen C van der Hilst, Reinoud Cartuyvels, Peter Messiaen, Inge C Gyssens,

<h4>Objectives</h4>To perform an audit of empirical antibiotic therapy (EAT) of sepsis at the emergency department and to analyse the impact of an antimicrobial stewardship (AMS) programme on process and patient outcomes.<h4>Patients and methods</h4>A prospective, single-centre cohort study including patients with sequential organ failure assessment (SOFA) score ≥2 from whom blood ... Read more >>

Int J Antimicrob Agents (International journal of antimicrobial agents)
[2021, 58(3):106379]

Cited: 0 times

View full text PDF listing >>



Hospital antibiotic prescribing patterns in adult patients according to the WHO Access, Watch and Reserve classification (AWaRe): results from a worldwide point prevalence survey in 69 countries.

Ines Pauwels, Ann Versporten, Nico Drapier, Erika Vlieghe, Herman Goossens, ,

<h4>Objectives</h4>The WHO Access, Watch and Reserve (AWaRe) classification has been developed to support countries and hospitals in promoting rational use of antibiotics while improving access to these essential medicines. We aimed to describe patterns of worldwide antibiotic use according to the AWaRe classification in the adult inpatient population.<h4>Methods</h4>The Global Point ... Read more >>

J Antimicrob Chemother (The Journal of antimicrobial chemotherapy)
[2021, 76(6):1614-1624]

Cited: 0 times

View full text PDF listing >>



Diagnosis of COVID-19 Based on Symptomatic Analysis of Hospital Healthcare Workers in Belgium: Observational Study in a Large Belgian Tertiary Care Center During Early COVID-19 Outbreak.

Nele Van Loon, Mathieu Verbrugghe, Reinoud Cartuyvels, Dirk Ramaekers,

<h4>Objective</h4>To identify early symptoms allowing rapid appraisal of infection with SARS-CoV-2 among healthcare workers of a large Belgian hospital.<h4>Methods</h4>Healthcare workers with mild symptoms of an acute respiratory tract infection were systematically screened on clinical characteristics of corona virus disease 2019 (COVID-19). A nasopharyngeal swab was taken and analyzed by real-time ... Read more >>

J Occup Environ Med (Journal of occupational and environmental medicine)
[2021, 63(1):27-31]

Cited: 4 times

View full text PDF listing >>



Risk Factors for Mortality, Intensive Care Unit Admission, and Bacteremia in Patients Suspected of Sepsis at the Emergency Department: A Prospective Cohort Study.

Valentino D'Onofrio, Agnes Meersman, Sara Vijgen, Reinoud Cartuyvels, Peter Messiaen, Inge C Gyssens,

<h4>Background</h4>There is a clear need for a better assessment of independent risk factors for in-hospital mortality, intensive care unit admission, and bacteremia in patients presenting with suspected sepsis at the emergency department.<h4>Methods</h4>A prospective observational cohort study including 1690 patients was performed. Two multivariable logistic regression models were used to identify ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2021, 8(1):ofaa594]

Cited: 0 times

View full text PDF listing >>



Differentiating influenza from COVID-19 in patients presenting with suspected sepsis.

Valentino D'Onofrio, Eveline Van Steenkiste, Agnes Meersman, Luc Waumans, Reinoud Cartuyvels, Karlijn Van Halem, Peter Messiaen, Inge C Gyssens,

There is a need for a quick assessment of severely ill patients presenting to the hospital. The objectives of this study were to identify clinical, laboratory and imaging parameters that could differentiate between influenza and COVID-19 and to assess the frequency and impact of early bacterial co-infection. A prospective observational ... Read more >>

Eur J Clin Microbiol Infect Dis (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2021, 40(5):987-995]

Cited: 1 time

View full text PDF listing >>



The clinical value of minimal invasive autopsy in COVID-19 patients.

Valentino D'Onofrio, Elena Donders, Marie-Elena Vanden Abeele, Jasperina Dubois, Reinoud Cartuyvels, Ruth Achten, Martin Lammens, Amelie Dendooven, Ann Driessen, Lukasz Augsburg, Jan Vanrusselt, Janneke Cox,

<h4>Background</h4>Minimally invasive autopsy (MIA) is a validated and safe method to establish the cause of death (COD), mainly in low-resource settings. However, the additional clinical value of MIA in Coronavirus disease (COVID-19) patients in a high-resource setting is unknown. The objective was to assess if and how MIA changed clinical ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242300]

Cited: 4 times

View full text PDF listing >>



The Clinical Impact of Rapid Molecular Microbiological Diagnostics for Pathogen and Resistance Gene Identification in Patients With Sepsis: A Systematic Review.

Valentino D'Onofrio, Lene Salimans, Branka Bedenić, Reinoud Cartuyvels, Ivan Barišić, Inge C Gyssens,

Fast microbiological diagnostics (MDx) are needed to ensure early targeted antimicrobial treatment in sepsis. This systematic review focuses on the impact on antimicrobial management and patient outcomes of MDx for pathogen and resistance gene identification compared with blood cultures. PubMed was searched for clinical studies using either whole blood directly ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2020, 7(10):ofaa352]

Cited: 1 time

View full text PDF listing >>



Vertical transmission of SARS-CoV-2 infection and preterm birth.

Bianca Pulinx, Davy Kieffer, Ian Michiels, Stéphanie Petermans, David Strybol, Sigrun Delvaux, Marcella Baldewijns, Marijke Raymaekers, Reinoud Cartuyvels, Wim Maurissen,

Viral infections are common complications of pregnancy, with a wide range of obstetric and neonatal sequelae. Currently, there are limited data on whether SARS-CoV-2 is vertically transmitted in pregnant women tested positive for the virus. Here we describe a case of a known SARS-CoV-2-positive woman giving preterm birth to two ... Read more >>

Eur J Clin Microbiol Infect Dis (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, 39(12):2441-2445]

Cited: 15 times

View full text PDF listing >>



Care for adult non-ICU Covid-19 patients: early experiences from a Belgian tertiary care centre.

K van Halem, J Cox, P Messiaen, K Pat, C Declercq, A Meersman, D Ramaekers, R Cartuyvels, J van der Hilst,

The current Covid-19 outbreak poses many challenges on hospital organisation and patient care. Our hospital lies at the epicentre of the Belgian epidemic. On April 1st, a total of 235 Covid-19 patients had been admitted to our hospital. This demanded an unprecedented adaptation of our hospital organisation, and we have ... Read more >>

Neth J Med (The Netherlands journal of medicine)
[2020, 78(3):111-115]

Cited: 4 times

View full text PDF listing >>



Point prevalence survey of antimicrobial use and healthcare-associated infections in Belgian acute care hospitals: results of the Global-PPS and ECDC-PPS 2017.

Eline Vandael, Katrien Latour, Herman Goossens, Koen Magerman, Nico Drapier, Boudewijn Catry, Ann Versporten, ,

<h4>Background</h4>The point prevalence survey of healthcare-associated infections (HAIs) and antimicrobial use organized by the European Centre for Disease Prevention and Control (ECDC-PPS) and the Global Point Prevalence Survey of antimicrobial consumption (Global-PPS) were simultaneously performed in Belgian acute care hospitals in 2017.<h4>Methods</h4>Belgian acute care hospitals were invited to participate in ... Read more >>

Antimicrob Resist Infect Control (Antimicrobial resistance and infection control)
[2020, 9(1):13]

Cited: 5 times

View full text PDF listing >>



Antibiotic prophylaxis in TURP: a prospective analysis concerning antibiotic stewardship and a potential reduction of antibiotic use in TURP.

E Baten, F Van Der Aa, C Orye, R Cartuyvels, I Arijs, K van Renterghem,

<h4>Purpose</h4>Antibiotic prophylaxis is standard procedure in transurethral resection of the prostate (TURP). We evaluated the necessity of antibiotic (AB) prophylaxis in TURP due to increasing microbial antibiotic resistance.<h4>Methods</h4>This is a prospective cohort study of 506 patients. Only patients with a pre-operative catheter/pyuria received AB-prophylaxis. Urine analysis (pre-operative, at discharge, and ... Read more >>

World J Urol (World journal of urology)
[2019, 37(11):2467-2472]

Cited: 1 time

View full text PDF listing >>



Use of fosfomycin as targeted antibiotic prophylaxis before prostate biopsy: A prospective randomized study.

Jeroen Van Besien, Pieter Uvin, Emmanuel Weyne, Charles Van Praet, Luc Merckx, Nico De Graeve, Koenraad Van Renterghem, Reinoud Cartuyvels, Anne-Marie Van den Abeele,

<h4>Objectives</h4>To investigate whether switching ciprofloxacin to fosfomycin in the case of fluoroquinolone-resistant rectal bacteria influences the incidence of infectious complications after transrectal prostate biopsy.<h4>Methods</h4>From December 2015 until December 2017, patients undergoing prostate biopsy were randomly assigned to a control group or an intervention group in a prospective, open-label fashion at ... Read more >>

Int J Urol (International journal of urology : official journal of the Japanese Urological Association)
[2019, 26(3):391-397]

Cited: 0 times

View full text PDF listing >>



Distribution of HCV genotypes in Belgium from 2008 to 2015.

Lobna Bouacida, Vanessa Suin, Veronik Hutse, Michaël Boudewijns, Reinoud Cartuyvels, Laurent Debaisieux, Emmanuel De Laere, Marie Hallin, Nicolas Hougardy, Katrien Lagrou, Els Oris, Elizaveta Padalko, Marijke Reynders, Gatien Roussel, Jean-Marc Senterre, Michel Stalpaert, Dominique Ursi, Carl Vael, Dolores Vaira, Jos Van Acker, Walter Verstrepen, Steven Van Gucht, Benoit Kabamba, Sophie Quoilin, Gaëtan Muyldermans,

<h4>Background</h4>The knowledge of circulating HCV genotypes and subtypes in a country is crucial to guide antiviral therapy and to understand local epidemiology. Studies investigating circulating HCV genotypes and their trends have been conducted in Belgium. However they are outdated, lack nationwide representativeness or were not conducted in the general population.<h4>Methods</h4>In ... Read more >>

PLoS One (PloS one)
[2018, 13(12):e0207584]

Cited: 1 time

View full text PDF listing >>



How to achieve accurate blood culture volumes: the BD BACTEC FX blood volume monitoring system as a measuring instrument and educational tool.

L Cattoir, J Claessens, R Cartuyvels, A M Van den Abeele,

Collecting adequate volumes of blood in blood culture bottles is crucial for sensitive detection of bacteremia and fungemia. Tools enabling easy collection of data on the degree of blood culture bottle filling at different hospital departments are an important step toward quality measurement and improvement. In this study, we verified ... Read more >>

Eur J Clin Microbiol Infect Dis (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2018, 37(9):1621-1626]

Cited: 1 time

View full text PDF listing >>



Laboratory diagnosis of urinary tract infections: Towards a BILULU consensus guideline.

Matthijs Oyaert, Britt Van Meensel, Reinoud Cartuyvels, Johan Frans, Wim Laffut, Patricia Vandecandelaere, Hans De Beenhouwer, ,

Urinary tract infections (UTI) are very common throughout life and account for the majority of the workload in the clinical microbiology laboratory. Clear instructions for the interpretation of urine cultures by the laboratory technicians are indispensable to obtain standardized, reliable, and clinically useful results. In literature, there is often a ... Read more >>

J Microbiol Methods (Journal of microbiological methods)
[2018, 146:92-99]

Cited: 3 times

View full text PDF listing >>



Outbreak of trichinellosis related to eating imported wild boar meat, Belgium, 2014.

Peter Messiaen, Annemie Forier, Steven Vanderschueren, Caroline Theunissen, Jochen Nijs, Marjan Van Esbroeck, Emmanuel Bottieau, Koen De Schrijver, Inge C Gyssens, Reinoud Cartuyvels, Pierre Dorny, Jeroen van der Hilst, Daniel Blockmans,

Trichinellosis is a rare parasitic zoonosis caused by Trichinella following ingestion of raw or undercooked meat containing Trichinella larvae. In the past five years, there has been a sharp decrease in human trichinellosis incidence rates in the European Union due to better practices in rearing domestic animals and control measures ... Read more >>

Euro Surveill (Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin)
[2016, 21(37):]

Cited: 9 times

View full text PDF listing >>



Etest® versus broth microdilution for ceftaroline MIC determination with Staphylococcus aureus: results from PREMIUM, a European multicentre study.

Rafael Cantón, David M Livermore, María Isabel Morosini, Jazmín Díaz-Regañón, Gian Maria Rossolini, ,

<h4>Objectives</h4>To compare the concordance of ceftaroline MIC values by reference broth microdilution (BMD) and Etest (bioMérieux, France) for MSSA and MRSA isolates obtained from PREMIUM (D372SL00001), a European multicentre study.<h4>Methods</h4>Ceftaroline MICs were determined by reference BMD and by Etest for 1242 MSSA and MRSA isolates collected between February and May ... Read more >>

J Antimicrob Chemother (The Journal of antimicrobial chemotherapy)
[2017, 72(2):431-436]

Cited: 8 times

View full text PDF listing >>



Technical and clinical validation of three commercial real-time PCR kits for the diagnosis of neuroborreliosis in cerebrospinal fluid on three different real-time PCR platforms.

L Maes, T Carolus, V De Preter, S Ignoul, R Cartuyvels, L Braeken, P-J D'Huys, V Saegeman, B Kabamba, M Raymaekers,

This study reports the evaluation of the technical and clinical validation of the O-DiaBorburg kit (DIA), Borrelia burgdorferi PCR kit, ISEX (GENE), and Borrelia burgdorferi sensu lato Real-TM (SAC) for the diagnosis of neuroborreliosis in cerebrospinal fluid based on both Borrelia DNA and CSF samples from patients with clinical suspicion ... Read more >>

Eur J Clin Microbiol Infect Dis (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2017, 36(2):273-279]

Cited: 1 time

View full text PDF listing >>



Development of a national EUCAST challenge panel for antimicrobial susceptibility testing.

S Desmet, J Verhaegen, Y Glupzcynski, J Van Eldere, P Melin, H Goossens, D Piérard, P Declercq, K Lagrou, A Boel, R Cartuyvels, O Denis, W Vandewal, V Saegeman,

A challenge panel of bacterial strains useful for clinical laboratories to validate their European Committee on Antimicrobial Susceptibility Testing (EUCAST) antimicrobial susceptibility test (AST) system was established. A total of 117 strains, obtained from Belgian Reference Centres (n = 57) and from routine clinical samples (n = 60) was selected based on resistance pattern. ... Read more >>

Clin Microbiol Infect (Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases)
[2016, 22(8):704-710]

Cited: 3 times

View full text PDF listing >>



Laboratory survey and literature review of anaerobic bacteriology: foundations of a clinically orientated and evidence-based workup for anaerobic cultures.

Bart Peeters, Koen Magerman, Luc Waumans, Reinoud Cartuyvels,

Since the introduction of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) in routine microbiology laboratories, identification of anaerobic bacteria has become easier. These increased possibilities provide new challenges concerning analytical workup and reporting of anaerobes. In February 2015, an extensive web-based survey on pre-analytical, analytical and post-analytical procedures ... Read more >>

Diagn Microbiol Infect Dis (Diagnostic microbiology and infectious disease)
[2016, 86(1):15-22]

Cited: 1 time

View full text PDF listing >>



A hospital-level cost-effectiveness analysis model for toxigenic Clostridium difficile detection algorithms.

E Verhoye, P Vandecandelaere, H De Beenhouwer, G Coppens, R Cartuyvels, A Van den Abeele, J Frans, W Laffut, ,

<h4>Background</h4>Despite thorough analyses of the analytical performance of Clostridium difficile tests and test algorithms, the financial impact at hospital level has not been well described. Such a model should take institution-specific variables into account, such as incidence, request behaviour and infection control policies.<h4>Aim</h4>To calculate the total hospital costs of different ... Read more >>

J Hosp Infect (The Journal of hospital infection)
[2015, 91(2):123-128]

Cited: 4 times

View full text PDF listing >>



Establishing quality control ranges for temocillin following CLSI-M23-A3 guideline.

W Maurissen, G De Sutter, H De Beenhouwer, J Frans, A-M Van den Abeele, R Cartuyvels, W Laffut, P Vandecandelaere, G Coppens,

<h4>Objectives</h4>This study aimed to establish acceptable quality control ranges for temocillin disk diffusion tests and Etest(®) minimal inhibitory concentrations.<h4>Methods</h4>According to Clinical and Laboratory Standards Institute (CLSI) guideline, a Tier 2 quality control study was performed and involves seven laboratories. Each of them tested 10 replicates of two quality control strains ... Read more >>

Acta Clin Belg (Acta clinica Belgica)
[2015, 70(1):11-15]

Cited: 0 times

View full text PDF listing >>



Advertisement


Disclaimer

1.4768 s