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The Relationship and Trends of Socio-Demographic Index, Healthy Life Expectancy and Life Expectancy in China

Xinlei Miao, Xiuhua Guo, Yue Cai, Xiang Zhang, Qun Meng,

Abstract Background Socio-Demographic Index (SDI) is an index to evaluate social development. Healthy life expectancy (HLE/HALE) can comprehensively measure the population health. This paper analyzes the relationship and trend of Socio-Demographic Index, life expectancy (LE) and healthy life expectancy, which provides a reference for improving population health. Methods We used ... Read more >>

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The Relationship and Trends of Socio-Demographic Index, Healthy Life Expectancy and Life Expectancy in China

Xinlei Miao, Xiuhua Guo, Yue Cai, Xiang Zhang, Qun Meng,

Abstract Background Socio-Demographic Index is an index to evaluate social development. Healthy life expectancy can comprehensively measure the population health. This paper indirectly infers the relationship between SDI and HALE, which provides a reference for improving population health. Methods We used SAS 9.4 to analyze the relationship between SDI and ... Read more >>

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The Association Between Normal BMI With Central Adiposity And Proinflammatory Potential Immunoglobulin G N-Glycosylation.

Di Liu, Qihuan Li, Jing Dong, Dong Li, Xizhu Xu, Weijia Xing, Xiaoyu Zhang, Weijie Cao, Haifeng Hou, Hao Wang, Manshu Song, Lixin Tao, Xiaoping Kang, Qun Meng, Wei Wang, Xiuhua Guo, Youxin Wang,

Background:The mechanism by which normal body mass index (BMI) with central adiposity (NWCA) increases the risk of the diseases has not been completely elucidated. The inflammatory role of immunoglobulin G (IgG) N-glycosylation in obesity defined by BMI or central adiposity defined by waist-to-hip ratio (WHR) was reported, respectively. We undertook ... Read more >>

Diabetes Metab Syndr Obes (Diabetes, metabolic syndrome and obesity : targets and therapy)
[2019, 12:2373-2385]

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A clinicopathological comparison between IgA nephropathy and Henoch-Schönlein purpura nephritis in children: use of the Oxford classification.

Xueqian Li, Mengmeng Tang, Xingfeng Yao, Nan Zhang, Jianfeng Fan, Nan Zhou, Qiang Sun, Zhi Chen, Qun Meng, Lei Lei, Hejia Zhang, Chen Ling, Lin Hua, Xiangmei Chen, Xiaorong Liu,

BACKGROUND:There is controversy over whether IgA nephropathy (IgAN) and Henoch-Schönlein purpura nephritis (HSPN) are the same diseases. This study focuses on the clinicopathological comparison between HSPN and IgAN in children. METHODS:Children with IgAN and HSPN who had a diagnostic renal biopsy were enrolled. This study collected the clinical data of ... Read more >>

Clin. Exp. Nephrol. (Clinical and experimental nephrology)
[2019, 23(12):1382-1390]

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Systematic Review: Immunoglobulin G N-Glycans as Next-Generation Diagnostic Biomarkers for Common Chronic Diseases.

Di Liu, Qihuan Li, Xiaoyu Zhang, Hao Wang, Weijie Cao, Dong Li, Weijia Xing, Manshu Song, Wei Wang, Qun Meng, Youxin Wang,

Glycomics is a new subspecialty in omics systems sciences that offers significant promise for next-generation biomarkers on disease susceptibility, drug target discovery, and precision medicine. In this context, alternative immunoglobulin G (IgG) N-glycosylation has been reportedly implicated in several common chronic diseases, although systematic assessment is currently lacking in the ... Read more >>

OMICS (Omics : a journal of integrative biology)
[2019, 23(12):607-614]

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The changes of immunoglobulin G N-glycosylation in blood lipids and dyslipidaemia.

Di Liu, Xi Chu, Hao Wang, Jing Dong, Si-Qi Ge, Zhong-Yao Zhao, Hong-Li Peng, Ming Sun, Li-Juan Wu, Man-Shu Song, Xiu-Hua Guo, Qun Meng, You-Xin Wang, Gordan Lauc, Wei Wang,

BACKGROUND:Alternative N-glycosylation has significant structural and functional consequences on immunoglobulin G (IgG) and can affect immune responses, acting as a switch between pro- and anti-inflammatory IgG functionality. Studies have demonstrated that IgG N-glycosylation is associated with ageing, body mass index, type 2 diabetes and hypertension. METHODS:Herein, we have demonstrated patterns ... Read more >>

J Transl Med (Journal of translational medicine)
[2018, 16(1):235]

Cited: 4 times

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Impact of the New Cooperative Medical Scheme on the trend of catastrophic health expenditure in Chinese rural households: results from nationally representative surveys from 2003 to 2013.

Biao Xie, Minghe Huo, Zhiqiang Wang, Yongjie Chen, Rong Fu, Meina Liu, Qun Meng,

OBJECTIVE:To evaluate the trend of catastrophic health expenses (CHE) for inpatient care in relation to the commencement of the New Cooperative Medical Scheme (NCMS) in rural China from 2003 to 2013, and the roles of NCMS in protecting affected households from CHE. METHODS:We assessed the 10-year trend of the incidence ... Read more >>

BMJ Open (BMJ open)
[2018, 8(2):e019442]

Cited: 5 times

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Geographic Variations in In‐Hospital Mortality and Use of Percutaneous Coronary Intervention Following Acute Myocardial Infarction in China: A Nationwide Cross‐Sectional Analysis.

Hui Chen, Lizheng Shi, Ming Xue, Ni Wang, Xiao Dong, Yue Cai, Jieqing Chen, Weiguo Zhu, Hua Xu, Qun Meng,

BackgroundPrevalence of acute myocardial infarction (AMI) is increasing in China, and AMI has become a major cause of mortality; however, information is very limited about the nationwide geographic and hospital variation in in‐hospital mortality (IHM) and the use of percutaneous coronary intervention (PCI) after AMI.Methods and ResultsFrom the Nationwide Hospital ... Read more >>

(Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease)
[2018, 7(8):]

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Urinary CD80 excretion is a predictor of good outcome in children with primary nephrotic syndrome.

Chen Ling, Xiaorong Liu, Ying Shen, Zhi Chen, Jianfeng Fan, Yeping Jiang, Qun Meng,

BACKGROUND:The level of urinary cluster of differentiation 80 (uCD80) is elevated in most children with minimal change disease (MCD) as opposed to focal segmental glomerulosclerosis (FSGS) during the acute phase. The objective of this follow-up study was to evaluate whether uCD80 elevation is actually associated with MCD and whether it ... Read more >>

Pediatr. Nephrol. (Pediatric nephrology (Berlin, Germany))
[2018, 33(7):1183-1187]

Cited: 2 times

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Does providing more services increase the primary hospitals' revenue? An assessment of national essential medicine policy based on 2,675 counties in China.

Fei Chen, Min Yang, Qian Li, Jay Pan, Xiaosong Li, Qun Meng,

To understand whether the increased outpatient service provision (OSP) brings in enough additional income (excluding income from essential medicine) for primary hospitals (INCOME) to compensate for reduced costs of medicine.The two outcomes, annual OSP and INCOME for the period of 2008-2012, were collected from 34,506 primary hospitals in 2,675 counties ... Read more >>

PLoS ONE (PloS one)
[2018, 13(1):e0190855]

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Analysis of inpatient payments of breast cancer patients with different medical insurance coverages in China (mainland) in 2011-2015.

Rui Li, Liang Zhang, Jinxia Yang, Yue Cai, Wanqing Chen, Lan Lan, Ming Xue, Qun Meng,

An understanding of the levels and trends of medical cost is made for breast cancer patients with different medical insurance coverages in China (mainland), in an attempt to offer a clue to further control the costs.The inpatient payments of 9,716,180 breast cancer patients spent in medical institutions of different types ... Read more >>

Chin. J. Cancer Res. (Chinese journal of cancer research = Chung-kuo yen cheng yen chiu)
[2017, 29(5):419-425]

Cited: 1 time

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The Effect of China's National Essential Medicine Policy on Health Expenses: Evidence From a National Study.

Qian Li, Fei Chen, Min Yang, Liyong Lu, Jay Pan, Xiaosong Li, Qun Meng,

To increase use of medical service across the country, the Chinese government has tried to improve equity in health care access and reduce patients' medical expenses. For this purpose, the National Essential Medicine Policy (NEMP) was introduced in 2009 to mandate the distribution of medicines to health care facilities at ... Read more >>

Inquiry (Inquiry : a journal of medical care organization, provision and financing)
[2018, 55:46958018787057]

Cited: 1 time

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Development of medical informatics in China over the past 30 years from a conference perspective and a Sino-American comparison.

Jun Liang, Kunyan Wei, Qun Meng, Zhenying Chen, Jiajie Zhang, Jianbo Lei,

As the world's second-largest economy, China has launched health reforms for the second time and invested significant funding in medical informatics (MI) since 2010; however, few studies have been conducted on the outcomes of this ambitious cause.This study analyzed the features of major MI meetings held in China and compared ... Read more >>

PeerJ (PeerJ)
[2017, 5:e4082]

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The Gap in Medical Informatics and Continuing Education Between the United States and China: A Comparison of Conferences in 2016.

Jun Liang, Kunyan Wei, Qun Meng, Zhenying Chen, Jiajie Zhang, Jianbo Lei,

BACKGROUND:China launched its second health reform in 2010 with considerable investments in medical informatics (MI). However, to the best of our knowledge, research on the outcomes of this ambitious undertaking has been limited. OBJECTIVE:Our aim was to understand the development of MI and the state of continuing education in China ... Read more >>

J. Med. Internet Res. (Journal of medical Internet research)
[2017, 19(6):e224]

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Expenditure of hospital care on cancer in China, from 2011 to 2015.

Yue Cai, Ming Xue, Wanqing Chen, Maogui Hu, Zhiwen Miao, Lan Lan, Rongshou Zheng, Qun Meng,

A solid understanding of levels and trends of spending on cancer is important to evaluate whether our healthcare resources were wisely spent and to prioritize future resources for cancer treatment and prevention. However, studies on economic burden of cancers in China are scant and the results are inconsistent.The Chinese hospital ... Read more >>

Chin. J. Cancer Res. (Chinese journal of cancer research = Chung-kuo yen cheng yen chiu)
[2017, 29(3):253-262]

Cited: 9 times

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Enabling Health Reform through Regional Health Information Exchange: A Model Study from China.

Jianbo Lei, Dong Wen, Xingting Zhang, Jiayu Li, Haiying Lan, Qun Meng, Dean F Sittig,

Objective. To investigate and share the major challenges and experiences of building a regional health information exchange system in China in the context of health reform. Methods. This study used interviews, focus groups, a field study, and a literature review to collect insights and analyze data. The study examined Xinjin's ... Read more >>

J Healthc Eng (Journal of healthcare engineering)
[2017, 2017:1053403]

Cited: 1 time

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Corneal cystine crystals in cystinosis.

Chen Ling, Xiaorong Liu, Zhi Chen, Yeping Jiang, Jianfeng Fan, Qun Meng, Qian Fu, Jifeng Yu,

Arch. Dis. Child. (Archives of disease in childhood)
[2017, 102(12):1185]

Cited: 0 times

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Combined methylmalonic acidemia and homocysteinemia presenting predominantly with late-onset diffuse lung disease: a case series of four patients.

Jinrong Liu, Yun Peng, Nan Zhou, Xiaorong Liu, Qun Meng, Hui Xu, Shunying Zhao,

Combined methylmalonic acidemia (MMA) and homocysteinemia are a group of autosomal recessive disorders caused by inborn errors of cobalamin metabolism, including CblC, D, F, and J, with cblC being the most common subtype. The clinical manifestations of combined MMA and homocysteinemia vary, but typically include neurologic, developmental and hematologic abnormalities.We ... Read more >>

Orphanet J Rare Dis (Orphanet journal of rare diseases)
[2017, 12(1):58]

Cited: 4 times

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Assessing dose-response effects of national essential medicine policy in China: comparison of two methods for handling data with a stepped wedge-like design and hierarchical structure.

Yan Ren, Min Yang, Qian Li, Jay Pan, Fei Chen, Xiaosong Li, Qun Meng,

OBJECTIVES:To introduce multilevel repeated measures (RM) models and compare them with multilevel difference-in-differences (DID) models in assessing the linear relationship between the length of the policy intervention period and healthcare outcomes (dose-response effect) for data from a stepped-wedge design with a hierarchical structure. DESIGN:The implementation of national essential medicine policy ... Read more >>

BMJ Open (BMJ open)
[2017, 7(2):e013247]

Cited: 2 times

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Influencing factors of inpatient expenditure pattern for cancer in China, 2015.

Lan Lan, Yue Cai, Tao Zhang, Ruixian Wu, Ming Xue, Qun Meng,

We analyzed the proportion of cancer-caused hospitalization expenses in total hospitalization expenses from national authoritative data and explored influencing factors of the proportion so as to provide effective data information for more rational utilization of health resources.Two-level lineal regression model was used to explore influencing factors of ratios of the ... Read more >>

Chin. J. Cancer Res. (Chinese journal of cancer research = Chung-kuo yen cheng yen chiu)
[2017, 29(1):11-17]

Cited: 4 times

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Enabling Health Reform through Regional Health Information Exchange: A Model Study from China

Jianbo Lei, Dong Wen, Xingting Zhang, Jiayu Li, Haiying Lan, Qun Meng, Dean F. Sittig,

To investigate and share the major challenges and experiences of building a regional health information exchange system in China in the context of health reform.This study used interviews, focus groups, a field study, and a literature review to collect insights and analyze data. The study examined Xinjin's approach to developing ... Read more >>

J Healthc Eng (Journal of healthcare engineering)
[2017, (2017):]

Cited: 0 times

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The evolution of medical informatics in China: A retrospective study and lessons learned.

Jianbo Lei, Qun Meng, Yuefeng Li, Minghui Liang, Kai Zheng,

In contrast to China's giant health information technology (HIT) market and tremendous investments in hospital information systems the contributions of Chinese scholars in medical informatics to the global community are very limited. China would like to have a more important position in the global medical informatics community.A better understanding of ... Read more >>

Int J Med Inform (International journal of medical informatics)
[2016, 92:8-14]

Cited: 3 times

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Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation.

Dong-Sheng Huang, Zhaohui Wang, Xu-Jun He, Bill H Diplas, Rui Yang, Patrick J Killela, Qun Meng, Zai-Yuan Ye, Wei Wang, Xiao-Ting Jiang, Li Xu, Xiang-Lei He, Zhong-Sheng Zhao, Wen-Juan Xu, Hui-Ju Wang, Ying-Yu Ma, Ying-Jie Xia, Li Li, Ru-Xuan Zhang, Tao Jin, Zhong-Kuo Zhao, Ji Xu, Sheng Yu, Fang Wu, Junbo Liang, Sizhen Wang, Yuchen Jiao, Hai Yan, Hou-Quan Tao,

Several somatic mutation hotspots were recently identified in the telomerase reverse transcriptase (TERT) promoter region in human cancers. Large scale studies of these mutations in multiple tumour types are limited, in particular in Asian populations. This study aimed to: analyse TERT promoter mutations in multiple tumour types in a large ... Read more >>

Eur. J. Cancer (European journal of cancer (Oxford, England : 1990))
[2015, 51(8):969-976]

Cited: 51 times

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Comparative analysis of preservation method and intermittent perfusion volume on the expression of endothelial and inflammatory markers by coronal artery and myocardium in porcine donor hearts.

Zhibin Hu, Zhikun Yan, Haitao Wang, Qun Meng, Xiaohua Pan,

Although continuous perfusion of donor hearts for preservation during transportation has been widely applied, intermittent perfusion has been suggested as an alternative. The aim of this study was to identify the optimal intermittent perfusion protocol by investigating the effects of perfusion volume on endothelial and inflammatory marker expression by the ... Read more >>

ASAIO J. (ASAIO journal (American Society for Artificial Internal Organs : 1992))
[2014, 60(6):681-687]

Cited: 1 time

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Urinary CD80 levels as a diagnostic biomarker of minimal change disease.

Chen Ling, Xiaorong Liu, Ying Shen, Zhi Chen, Jianfeng Fan, Yeping Jiang, Qun Meng,

Early diagnosis of minimal change disease (MCD) in nephrotic syndrome (NS) patients remains challenging. Doctors often make a diagnosis of MCD using invasive renal biopsy. CD80, a transmembrane protein, is present on podocytes in a number of experimental models of NS. Urinary CD80 levels are significantly elevated in MCD but ... Read more >>

Pediatr. Nephrol. (Pediatric nephrology (Berlin, Germany))
[2015, 30(2):309-316]

Cited: 15 times

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