Full Text Journal Articles by
Author Qianping Shi


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High MTHFR promoter methylation levels in men confer protection against ischemic stroke.

Shan Xu, Qianping Shi, Bo Li, Liyuan Han, Guodong Xu, Xiaolin Peng, Hongen Chen, Shuhong Dai, Wancheng Ma, Changyi Wang, Jianping Ma,

The MTHFR gene encodes methylenetetrahydrofolate reductase required for the metabolism of homocysteine (Hcy) - a previously reported independent risk factor for ischemic stroke (IS). In this study, we first aimed to clarify the association between DNA methylation levels in the MTHFR promoter and the risk of IS, followed by the ... Read more >>

Bosn J Basic Med Sci (Bosnian journal of basic medical sciences)
[2020, 20(4):477-486]

Cited: 0 times

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Comparative Metabolomic Analysis of the Neuroprotective Effects of Scutellarin and Scutellarein against Ischemic Insult.

Hao Tang, Yuping Tang, Nian-Guang Li, Hang Lin, Weixia Li, Qianping Shi, Wei Zhang, Pengxuan Zhang, Zexi Dong, Minzhe Shen, Ting Gu, Jin-Ao Duan,

For more than thirty years, scutellarin (Scu) has been used in China to clinically treat acute cerebral infarction and paralysis. Scutellarein (Scue), the major Scu metabolite in vivo, exhibits heightened neuroprotective effects when compared to Scu. To explore the neuroprotective role of these compounds, we performed ultra-high-performance liquid chromatography-quadrupole/time-of-flight mass ... Read more >>

PLoS One (PloS one)
[2015, 10(7):e0131569]

Cited: 9 times

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pH-responsive anionic wormlike micelle based on sodium oleate induced by NaCl.

Hongsheng Lu, Qianping Shi, Zhiyu Huang,

A pH-responsive anionic surfactant wormlike micellar system induced by NaCl has been developed. In this work, the anionic surfactant, sodium oleate (NaOA) solutions, transforms from low-viscosity fluid into high-viscoelastic solution induced by NaCl of 200 mM to 350 mM concentration. According to the above, the solution reversibility has been studied ... Read more >>

J Phys Chem B (The journal of physical chemistry. B)
[2014, 118(43):12511-12517]

Cited: 7 times

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Neuroprotective effects of scutellarin and scutellarein on repeatedly cerebral ischemia-reperfusion in rats.

Hao Tang, Yuping Tang, Nianguang Li, Qianping Shi, Jianming Guo, Erxin Shang, Jin-ao Duan,

Scutellarin had protective effects against neuronal injury, however, there are few studies on the protective effect of scutellarein, which is the main metabolite of scutellarin in vivo. This study investigated whether the neural injury by ischemia/reperfusion would be influenced by different doses of scutellarin and scutellarein. Male Wistar rats were ... Read more >>

Pharmacol Biochem Behav (Pharmacology, biochemistry, and behavior)
[2014, 118:51-59]

Cited: 23 times

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Synthesis and protective effect of scutellarein on focal cerebral ischemia/reperfusion in rats.

Lihua Qian, Minzhe Shen, Hao Tang, Yuping Tang, Li Zhang, Yifan Fu, Qianping Shi, Nian-Guang Li,

Scutellarein, the main metabolite of scutellarin in vivo, has relatively better solubility, bioavailability and bio-activity than scutellarin. However, compared with scutellarin, it is very difficult to obtain scutellarein from Nature. Therefore, the present study focused on establishing an efficient route for the synthesis of scutellarein by hydrolyzing scutellarin. Neurological deficit ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2012, 17(9):10667-10674]

Cited: 17 times

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