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Retarding effect of dietary fibers from bamboo shoot (Phyllostachys edulis) in hyperlipidemic rats induced by a high-fat diet.

Qi Li, Xiangjun Fang, Hangjun Chen, Yanchao Han, Ruiling Liu, Weijie Wu, Haiyan Gao,

The effects of the administration of bamboo shoot (Phyllostachys edulis) dietary fiber (BSDF) on high-fat diet (HDF) induced hyperlipidemia were studied with SD rat models. The results indicated that the body weight of rats and the mass of their adipose tissue were significantly (P < 0.05) decreased after the combination ... Read more >>

Food Funct (Food & function)
[2021, 12(10):4696-4706]

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The interaction of canonical Wnt/β-catenin signaling with protein lysine acetylation.

Hongjuan You, Qi Li, Delong Kong, Xiangye Liu, Fanyun Kong, Kuiyang Zheng, Renxian Tang,

Canonical Wnt/β-catenin signaling is a complex cell-communication mechanism that has a central role in the progression of various cancers. The cellular factors that participate in the regulation of this signaling are still not fully elucidated. Lysine acetylation is a significant protein modification which facilitates reversible regulation of the target protein ... Read more >>

Cell Mol Biol Lett (Cellular & molecular biology letters)
[2022, 27(1):7]

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Sedimentary spectrum and potential ecological risks of residual pharmaceuticals in relation to sediment-water partitioning and land uses in a watershed.

Bing Hong, Shen Yu, Min Zhou, Juan Li, Qi Li, Jing Ding, Qiaoying Lin, Xiaodan Lin, Xun Liu, Peiji Chen, Linlin Zhang,

Pharmaceutical residues in river surficial sediment are prone to anthropogenic impacts and environmental factors in watershed, but the mechanisms remain unclear. This study attempted to reveal surficial sediment-water pseudo-partitioning and anthropogenic (land use) patterns of pharmaceutical residues in surficial sediment among 23 subwatersheds of Jiulong River, southeast China with a ... Read more >>

Sci Total Environ (The Science of the total environment)
[2022, 817:152979]

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Genome-Wide Differential DNA Methylomes Provide Insights into the Infertility of Triploid Oysters.

Dongfang Sun, Hong Yu, Qi Li,

Chromosomal incompatibility and gene expression changes would affect the development of polyploid gonad and gamete formation. The role of epigenetics like DNA methylation in reproductive development is fully demonstrated in diploid animals. The lack of polyploid species and the infertility of polyploid animals, especially the odd ploidy, limit the study ... Read more >>

Mar Biotechnol (NY) (Marine biotechnology (New York, N.Y.))
[2022, :]

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A new screening system for entry inhibitors based on cell-to-cell transmitted syncytia formation mediated by self-propagating hybrid VEEV-SARS-CoV-2 replicon.

Na Li, Xiao-Ling Chen, Qi Li, Zhe-Rui Zhang, Cheng-Lin Deng, Bo Zhang, Xiao-Dan Li, Han-Qing Ye,

<b>Abstract</b>The extremely high transmission rate of SARS-CoV-2 and severe cases of COVID-19 pose the two critical challenges in the battle against COVID-19. Increasing evidence has shown that the viral spike (S) protein-driven syncytia may be responsible for these two events. Intensive attention has thus been devoted to seeking S-guided syncytium ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2022, :1-28]

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Collateral cleavage of 28s rRNA by RfxCas13d causes death of mice

Yunfei Li, Junjie Xu, Xuefei Guo, Zhiwei Li, Lili Cao, Shengde Liu, Ying Guo, Guodong Wang, Yujie Luo, Zeming Zhang, Xuemei Wei, Yingchi Zhao, Tongtong Liu, Xiao Wang, Huawei Xia, Ming Kuang, Qirui Guo, Junhong Li, Luoying Chen, Yibing Wang, Qi Li, Fengchao Wang, Qinghua Liu, Fuping You,

<h4>Summary: </h4> The CRISPR-Cas13 system is an RNA-guided RNA-targeting system, and has been widely used in transcriptome engineering with potentially important clinical applications. However, it is still controversial whether Cas13 exhibits collateral activity in mammalian cells. Here, we found that knocking down gene expression using RfxCas13d in the adult brain ... Read more >>

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MicroRNA Transcriptomics Analysis Identifies Dysregulated Hedgehog Signaling Pathway in a Mouse Model of Acute Intracerebral Hemorrhage Exposed to Hyperglycemia.

Wen-Song Yang, Yi-Qing Shen, Xun Yang, Xin-Hui Li, Shao-Hua Xu, Li-Bo Zhao, Rui Li, Xin Xiong, Shun-Jie Bai, Qing-Yuan Wu, Anatol Manaenko, Qi Li, Peng Xie,

<h4>Objective</h4>Hyperglycemia is often observed in the patients after acute stroke. This study aims to elucidate the potential effect and mechanism of hyperglycemia by screening microRNAs expression in intracerebral hemorrhage mice.<h4>Methods</h4>We employed the collagenase model of intracerebral hemorrhage. Twenty male C57BL/6 mice were used and randomly divided in normo- and hyperglycemic. ... Read more >>

J Stroke Cerebrovasc Dis (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association)
[2022, 31(3):106281]

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Concordance analysis of diatom types and patterns in lung tissue and drowning medium in laboratory animal model.

Yukun Du, Jingjian Liu, Qi Li, Huan Li, Xiaodong Kang, Dongyun Zheng, He Shi, Quyi Xu, Chao Liu, Huijun Wang, Jian Zhao,

Diatom test has been widely used in the diagnosis of drowning and inferring the drowning site. One of the issues is whether the concordance of the diatom types and patterns between the drowning victim's organs and media should be considered an essential requirement for the diagnosis of drowning. In this ... Read more >>

Int J Legal Med (International journal of legal medicine)
[2022, :]

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Publisher Correction: Toripalimab or placebo plus chemotherapy as first-line treatment in advanced nasopharyngeal carcinoma: a multicenter randomized phase 3 trial.

Hai-Qiang Mai, Qiu-Yan Chen, Dongping Chen, Chaosu Hu, Kunyu Yang, Jiyu Wen, Jingao Li, Ying-Rui Shi, Feng Jin, Ruilian Xu, Jianji Pan, Shenhong Qu, Ping Li, Chunhong Hu, Yi-Chun Liu, Yi Jiang, Xia He, Hung-Ming Wang, Wan-Teck Lim, Wangjun Liao, Xiaohui He, Xiaozhong Chen, Zhigang Liu, Xianglin Yuan, Qi Li, Xiaoyan Lin, Shanghua Jing, Yanju Chen, Yin Lu, Ching-Yun Hsieh, Muh-Hwa Yang, Chia-Jui Yen, Jens Samol, Hui Feng, Sheng Yao, Patricia Keegan, Rui-Hua Xu,

Nat Med (Nature medicine)
[2022, :]

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Radiological classification, gene-mutation status, and surgical prognosis of synchronous multiple primary lung cancer.

Ji-Wen Huo, Tian-You Luo, Xiao-Qun He, Jun-Wei Gong, Fa-Jin Lv, Qi Li,

<h4>Objective</h4>To investigate the radiological classification, gene-mutation status, and surgical prognosis of synchronous multiple primary lung cancer (sMPLC).<h4>Methods</h4>From January 2013 to October 2019, 192 consecutive patients with sMPLC were investigated. The clinical, CT, molecular, and pathological features of all patients were analyzed. Furthermore, the prognosis of 89 patients who only underwent ... Read more >>

Eur Radiol (European radiology)
[2022, :]

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Alleviative effect of melatonin on the decrease of uterine receptivity caused by blood ammonia through ROS/NF-κB pathway in dairy cow.

Peng Zheng, Xue Qin, Rui Feng, Qi Li, Fushuo Huang, Yulong Li, Qian Zhao, He Huang,

High concentration of blood ammonia can affect the uterus receptivity and decrease fecundity in dairy cow. Melatonin can reduce reactive oxygen species (ROS) level and has antioxidant and anti-inflammatory effects. However, it is not clear whether melatonin can alleviate ammonia-induced apoptosis of endometrial epithelial cell (EEC) and reduced uterus receptivity. ... Read more >>

Ecotoxicol Environ Saf (Ecotoxicology and environmental safety)
[2022, 231:113166]

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Decarboxylative cross-nucleophile coupling via ligand-to-metal charge transfer photoexcitation of Cu(II) carboxylates.

Qi Yukki Li, Samuel N Gockel, Grace A Lutovsky, Kimberly S DeGlopper, Neil J Baldwin, Mark W Bundesmann, Joseph W Tucker, Scott W Bagley, Tehshik P Yoon,

Reactions that enable carbon-nitrogen, carbon-oxygen and carbon-carbon bond formation lie at the heart of synthetic chemistry. However, substrate prefunctionalization is often needed to effect such transformations without forcing reaction conditions. The development of direct coupling methods for abundant feedstock chemicals is therefore highly desirable for the rapid construction of complex ... Read more >>

Nat Chem (Nature chemistry)
[2022, 14(1):94-99]

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Solid-state cooling by elastocaloric polymer with uniform chain-lengths.

Shixian Zhang, Quanling Yang, Chenjian Li, Yuheng Fu, Huaqing Zhang, Zhiwei Ye, Xingnan Zhou, Qi Li, Tao Wang, Shan Wang, Wenqing Zhang, Chuanxi Xiong, Qing Wang,

Although the elastocaloric effect was found in natural rubber as early as 160 years ago, commercial elastocaloric refrigeration based on polymer elastomers has stagnated owing to their deficient elastocaloric effects and large extension ratios. Herein, we demonstrate that polymer elastomers with uniform molecular chain-lengths exhibit enormous elastocaloric effects through reversible ... Read more >>

Nat Commun (Nature communications)
[2022, 13(1):9]

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Industry-Oriented Method for Dynamic Force Identification in Peripheral Milling Based on FSC-LSQR Using Acceleration Signals

Maxiao Hou, Hongrui Cao, Qi Li, Jianghai Shi,

Online measurement of milling force play a vital role in enabling machining process monitoring and control. In practice, the milling force is difficult to be measured directly with the dynamometer. This paper develops a novel method for milling force identification called least square QR-factorization with fast stopping criterion (FSC-LSQR) method, ... Read more >>

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Integrated comparison of growth and oxidative stress induced by tylosin in two freshwater algae Chlorella vulgaris and Raphidocelis subcapitata.

Denglong Lu, Zhihua Ma, Jianglin Peng, Yibo Zhang, Shan Liu, Qi Li,

Two model algae, Chlorella vulgaris (C. vulgaris) and Raphidocelis subcapitata (R. subcapitata), are commonly used in registration procedures to evaluate compounds with antimicrobial capacity. However, it has been found that these two algae show considerable differences in sensitivity when exposed to antibiotics. The selection of a suitable test species plays ... Read more >>

Ecotoxicology (Ecotoxicology (London, England))
[2022, :]

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Efficient Microcystis removal and sulfonamide-resistance gene propagation mitigation by constructed wetlands and functional genes analysis.

Bo Wang, Qin Peng, Rui Wang, Shuhua Yu, Qi Li, Chunping Huang,

Increasingly prevalent Microcystis blooms and the propagation of the associated resistance genes represent global environmental problems. Constructed wetlands (CWs) are a cost-effective technology used for wastewater treatment. In this study, the herb Alisma orientale and three industrial byproducts, namely, blast furnace slag, biochar, and sawdust, were selected to construct mini-CW ... Read more >>

Chemosphere (Chemosphere)
[2022, :133481]

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Gamma Knife Radiosurgery Versus Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma With Portal Vein Tumor Thrombus: a Propensity Score Matching Study

Ke Su, Tao Gu, Ke Xu, Jing Wang, Hongfei Liao, Xueting Li, Lianbin Wen, Yanqiong Song, Jiaqi Zhong, Bingsheng He, Xin Liu, Jie He, Yanlin Liu, Qi Li, Xunjie Feng, Siyu Chen, Binbin Yang, Weihong Huang, Hongping Jin, Xiaotong Luo, Teng Hu, Jiali Chen, Zhenying Wu, Simin Lu, Jianwen Zhang, Mingyue Rao, Yunchuan Xie, Jing Wang, Xiaoning Zhu, Lan Chen, Bo Li, Song Su, Xiaoli Yang, Juan Wang, Hao Zeng, Pan Wang, Min Yan, Xiaojing Chen, Kun He, Yunwei Han,

<h4>Background: </h4> The optimal management for hepatocellular carcinoma (HCC) patients with portal vein tumor thrombus (PVTT) is unclear. This study aimed to investigate the efficacy of Gamma knife radiosurgery (GKR) versus transcatheter arterial chemoembolization (TACE) in HCC patients with PVTT. <h4>Methods: </h4> This retrospective study included 572 HCC patients with ... Read more >>

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Synergistic Effects of a CeO2/SmMn2O5-H Diesel Oxidation Catalyst Induced by Acid-Selective Dissolution Drive the Catalytic Oxidation Reaction.

Qilei Yang, Qi Li, Xiyang Wang, Xiao Wang, Lei Li, Xuefeng Chu, Dong Wang, Jishuai Men, Xinbo Li, Wenzhe Si, Yue Peng, Yongliang Ma, Junhua Li,

A diesel oxidation catalyst (DOC) is installed upstream of an exhaust after-treatment line to remove CO and hydrocarbons and generate NO<sub>2</sub>. The catalyst should possess both good oxidation ability and thermal stability because it sits after the engine. We present a novel high-performance DOC with high steam resistance and thermal ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2022, :]

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Safety and immunogenicity of a heterologous boost with a recombinant vaccine, NVSI-06-07, in the inactivated vaccine recipients from UAE: a phase 2 randomised, double-blinded, controlled clinical trial

Nawal AlKaabi, Yun Kai Yang, Jing Zhang, Ke Xu, Yu Liang, Yun Kang, Ji Guo Su, Tian Yang, Salah Hussein, Mohamed Saif ElDein, Shuai Shao, Sen Sen Yang, Wenwen Lei, Xue Jun Gao, Zhiwei Jiang, Hui Wang, Meng Li, Hanadi Mekki Mekki, Walid Zaher, Sally Mahmoud, Xue Zhang, Chang Qu, Dan Ying Liu, Jing Zhang, Mengjie Yang, Islam ElTantawy, Peng Xiao, Zhao Nian Wang, Jin Liang Yin, Xiao Yan Mao, Jin Zhang, Ning Liu, Fu Jie Shen, Liang Qu, Yun Tao Zhang, Xiao Ming Yang, Guizhen Wu, Qi Ming Li,

<h4>Summary</h4> <h4>Background</h4> The increased coronavirus disease 2019 (COVID-19) breakthrough cases pose the need of booster vaccinations. In this study, we reported the safety and immunogenicity of a heterologous boost with a recombinant COVID-19 vaccine (CHO cells), named NVSI-06-07, as a third dose in participants who have previously received two doses ... Read more >>

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[Inhibitory Effects of Soil Amendment Coupled with Water Management on the Accumulation of Cd and Pb in Double-Cropping Rice].

Lin-Feng Li, Yan-Hong Wang, Yi-Chun Li, Ming-Deng Tang, Qi Li, Shao-Ying Ai,

The bioavailability of heavy metals in soil and the physiological activities of rice determine the accumulation of heavy metals in brown rice. In this study, a field experiment was conducted in a rice paddy in which the total amount of Cd in the soil did not exceed the national standard, ... Read more >>

Huan Jing Ke Xue (Huan jing ke xue= Huanjing kexue)
[2022, 43(1):472-480]

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Prognosis and survival analysis of patients with pancreatic cancer: retrospective experience of a single institution.

Qi Li, Zijian Feng, Ruyi Miao, Xun Liu, Chenxi Liu, Zhen Liu,

<h4>Background</h4>The overall survival of patients  with pancreatic cancer is extremely low. Despite multiple large-scale studies, identification of predictors of patient survival remains challenging. This study aimed to investigate the prognostic factors for pancreatic cancer.<h4>Methods</h4>The clinical data of 625 patients with pancreatic cancer treated at Shengjing Hospital of China Medical University ... Read more >>

World J Surg Oncol (World journal of surgical oncology)
[2022, 20(1):11]

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Measuring Solute Concentration with Terahertz Time-Domain Spectroscopy in Single and Multiphase Systems.

Johanna Kölbel, Qi Li, Terence L Threlfall, J Axel Zeitler,

A versatile setup based on a microfluidic platform allows investigation of liquid samples at various temperatures with terahertz time-domain spectroscopy. The setup is applied to develop a novel method that performs temperature and concentration calibrations of liquid samples at terahertz frequencies. Other than measuring the concentration of pure liquid phase ... Read more >>

Anal Chem (Analytical chemistry)
[2022, :]

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[A preliminary study on low temperature plasma obliteration for pyriform sinus fistula by visual laryngoscope].

Wei Li, Zhenghua Huang, Qi Li,

<b>Objective:</b>To investigate the effect of low-temperature plasma obliteration for pyriform sinus fistula by visual laryngoscope. <b>Methods:</b>The clinical data of 29 cases with congenital pyriform sinus fistula receiving low temperature plasma obliteration by visual laryngoscope during March 2019 to August 2021 was retrospectively analyzed in department of Otolaryngology Head and Neck ... Read more >>

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery)
[2022, 36(1):51-54]

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Combined berberine and probiotic treatment as an effective regimen for improving postprandial hyperlipidemia in type 2 diabetes patients: a double blinded placebo controlled randomized study.

Shujie Wang, Huahui Ren, Huanzi Zhong, Xinjie Zhao, Changkun Li, Jing Ma, Xuejiang Gu, Yaoming Xue, Shan Huang, Jialin Yang, Li Chen, Gang Chen, Shen Qu, Jun Liang, Li Qin, Qin Huang, Yongde Peng, Qi Li, Xiaolin Wang, Yuanqiang Zou, Zhun Shi, Xuelin Li, Tingting Li, Huanming Yang, Shenghan Lai, Guowang Xu, Junhua Li, Yifei Zhang, Yanyun Gu, Weiqing Wang,

Non-fasting lipidemia (nFL), mainly contributed by postprandial lipidemia (PL), has recently been recognized as an important cardiovascular disease (CVD) risk as fasting lipidemia (FL). PL serves as a common feature of dyslipidemia in Type 2 Diabetes (T2D), albeit effective therapies targeting on PL were limited. In this study, we aimed ... Read more >>

Gut Microbes (Gut microbes)
[2022, 14(1):2003176]

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ViRBase v3.0: a virus and host ncRNA-associated interaction repository with increased coverage and annotation.

Jun Cheng, Yunqing Lin, Linfu Xu, Kechen Chen, Qi Li, Kaixin Xu, Lin Ning, Juanjuan Kang, Tianyu Cui, Yan Huang, Xiaoyang Zhao, Dong Wang, Yanhui Li, Xi Su, Bin Yang,

As a means to aid in the investigation of viral infection mechanisms and identification of more effective antivirus targets, the availability of a source which continually collects and updates information on the virus and host ncRNA-associated interaction resources is essential. Here, we update the ViRBase database to version 3.0 (http://www.virbase.org/ ... Read more >>

Nucleic Acids Res (Nucleic acids research)
[2022, 50(D1):D928-D933]

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