Full Text Journal Articles by
Author Qazi Najam Us Saqib

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Ex-vivo abortifacient activity of Androsace foliosa n-hexane leaves extract on isolated rabbit uterus.

Jawad Zaheer, Qazi Najam-Us-Saqib, Asif Mehmmod Hashmi, Muhammad Mukhtiar, Sadia Zafar, Muhammad Riaz, Ghulam Rasool, Muhammad Akram, Syed Muhammad-Ali Shah, Saher Rahat, Faid Said Khan,

Androsace foliosa is a medicinal herb utilized in different areas of Pakistan for abortifacient, diabetic and liver complications. In the current research, the possible action of the n-hexane leaves extract of the Androsace foliosa on isolated rabbit uterus was examined. Abortifacient activity was examined in the existence of standard antagonist ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2019, 32(5(Supplementary)):2333-2339]

Cited: 0 times

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Phenolic contents, elemental analysis, antioxidant and lipoxygenase inhibitory activities of Zanthoxylum armatum DC fruit, leaves and bark extracts.

Fiaz Alam, Qazi Najam Us Saqib, Mohammad Ashraf,

Zanthoxylum armatum (DC) is a traditional spice and important herb used in Asia as a part of food and household medicine for the treatment of various conditions. The present study was designed to investigate in vitro for phenolic/flavonoid contents, antioxidant activities, lipoxygenase inhibitory activity, minerals and heavy-metal contents. The leaves, ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2019, 32(4):1703-1708]

Cited: 0 times

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Zanthoxylum armatum DC extracts from fruit, bark and leaf induce hypolipidemic and hypoglycemic effects in mice- in vivo and in vitro study.

Fiaz Alam, Qazi Najam Us Saqib, Mohammad Ashraf,

Zanthoxylum armatum DC is an important medicinal plant of south East Asia, and has been used to treat various ailments in traditional medicine including diabetes. This study investigated the in vitro and in vivo antidiabetic and biochemical effects of extracts of Z. armatum in mice.The extracts of fruit, bark and leaf ... Read more >>

BMC Complement Altern Med (BMC complementary and alternative medicine)
[2018, 18(1):68]

Cited: 3 times

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Evaluation of Zanthoxylum armatum Roxb for in vitro biological activities.

Fiaz Alam, Qazi Najam Us Saqib,

Zanthoxylum armatum fruits are used traditionally as a spice in various food preparations. The aim of this study was analysis of antimicrobial, cytotoxic, phytotoxic, insecticidal, and anti-leishmanial activity. The crude extract showed 86 ± 10% antifungal activity (Agar tube dilution method) against Trichophyton longifusis while n-hexane, chloroform, and aqueous-methanol fractions inhibited this ... Read more >>

J Tradit Complement Med (Journal of traditional and complementary medicine)
[2017, 7(4):515-518]

Cited: 2 times

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Gut modulatory and butyrylcholinesterase inhibitory activities of Gaultheria trichophylla.

Fiaz Alam, Qazi Najam Us Saqib, Abdul Jabbar Shah, Muhammad Ashraf, Quarat Al Ain,

Gaultheria trichophylla Royle (Ericaceae) and related species have been used in the traditional system of medicine for the treatment of diarrhoea, pain and inflammation.The present investigation explores G. trichophylla for its potential activity in hyperactive gut disorders.Antidiarrheal activity was evaluated on castor oil induced diarrhoea in mice with reference to ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2016, 54(12):2917-2921]

Cited: 3 times

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Coagulopathies in Naja naja karachiensis (black Pakistan cobra) bites and its effect on coagulation tests upon storage of platelet-poor plasma.

Muhammad Hassham Hassan Bin Asad, Muhammad Tahir Razi, Taous Khan, Qazi Najam-Us-saqib, Ghulam Murtaza, Muhammad Shahzad Hussain, Muhammad Sikandar Hussain, Sabiha Karim, Izhar Hussain,

The aim of this study was to evaluate the effect of venom from Naja naja karachiensis on platelet-poor plasma, activated partial thromboplastin time (aPTT), prothrombin time (PT) / international normalized ratio (INR), thrombin time (TT) and to evaluate its effect on clotting time upon storage of plasma for a specific ... Read more >>

Acta Pol Pharm (Acta poloniae pharmaceutica)
[2012, 69(6):1031-1034]

Cited: 4 times

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Antihaemorrhagic potentials of Fagonia cretica against Naja naja karachiensis (black Pakistan cobra) venom.

Muhammad Tahir Razi, Muhammad Hassham Hassan Bin Asad, Taous Khan, Muhammad Zabta Chaudhary, Muhammad Tayyab Ansari, Muhammad Anwar Arshad, Qazi Najam-us Saqib,

Plants have been extensively used as a remedy for the treatment of snake bites. The aim of this study was to determine the antivenom potentials of methanolic extract from the aerial parts (leaves and twigs) of Fagonia cretica L. on a haemorrhage induced by venom from Naja naja karachiensis. The ... Read more >>

Nat. Prod. Res. (Natural product research)
[2011, 25(20):1902-1907]

Cited: 8 times

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Anti-tumor 12-deoxyphorbol esters from Euphorbia cornigera.

Imam Bakhsh Baloch, Musa Kaleem Baloch, Qazi Najam us Saqib,

Nine (1-8 and 10) new and two (9 and 11) known compounds have been isolated from roots of Euphorbia cornigera Boiss. Their structure and relative stereochemistry were acquired through NMR ((1)H, (13)C, COSY-45, HOHAHA, HMQC, HMBC, NOE and HMBC) spectroscopic measurements. Compounds 1-10 were identified as diesters of 13,20-O-diacyl and ... Read more >>

Eur J Med Chem (European journal of medicinal chemistry)
[2008, 43(2):274-281]

Cited: 9 times

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