Full Text Journal Articles by
Author Qasim Khan

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Venetoclax-based rational combinations are effective in models of MYCN-amplified neuroblastoma.

Krista M Dalton, Kateryna Krytska, Timonthy L Lochmann, Renata Sano, Colleen Casey, Alessia D'Aulerio, Qasim A Khan, Giovanna Stein Crowther, Colin Coon, JinYang Cai, Sheeba Jacob, Richard Kurupi, Bin Hu, Mikhail Dozmorov, Patricia Greninger, Andrew J Souers, Cyril H Benes, Yaël P Mossé, Anthony C Faber,

Venetoclax is a small molecule inhibitor of the pro-survival protein BCL-2 that has gained market approval in BCL-2 dependent hematological cancers including chronic lymphocytic leukemia and acute myeloid leukemia. Neuroblastoma (NB) is a heterogenous pediatric cancer with a five-year survival rate of less than 50% for high-risk patients, which include ... Read more >>

Mol Cancer Ther (Molecular cancer therapeutics)
[2021, :]

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P138 What are medical students’ perceptions of human factors in simulated learning events: a thematic analysis

Alex Tebbett, Jo Jennings, Chris Bannon, Mike Brown, Qasim Khan, Ben Shuker, Rathinavel Shanmugam, Mohan Ranganathan,

Abstract <h4>Introduction</h4> Human factors, such as communication skills, are imperative to good patient care. In post-simulation debriefs we discuss these non-technical skills with medical students regularly, but do we have a good appreciation of what the terms mean to them, or what aspects of behaviour, good or bad, they focus ... Read more >>

BJS Open (BJS open)
[2021, 5(Suppl 1):]

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Re-evaluating the asymmetric conventional energy and renewable energy consumption-economic growth nexus for Pakistan.

Muhammad Afaq Haider Jafri, Huizheng Liu, Ahmed Usman, Qasim Raza Khan,

To understand the nexus between economic growth and energy sources, in this study, we have selected Pakistan and collected data over the period 1980-2016. The neoclassical production function of Pakistan is augmented with conventional and renewable energy, capital, and labor. Conversely, the conventional and renewable models are being constructed by ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2021, :]

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Evolution of low-dimensional material-based field-effect transistors.

Waqas Ahmad, Youning Gong, Ghulam Abbas, Karim Khan, Maaz Khan, Ghafar Ali, Ahmed Shuja, Ayesha Khan Tareen, Qasim Khan, Delong Li,

Field-effect transistors (FETs) have tremendous applications in the electronics industry due to their outstanding features such as small size, easy fabrication, compatibility with integrated electronics, high sensitivity, rapid detection and easy measuring procedures. However, to meet the increasing demand of the electronics industry, efficient FETs with controlled short channel effects, ... Read more >>

Nanoscale (Nanoscale)
[2021, 13(10):5162-5186]

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Review on the hazardous applications and photodegradation mechanisms of chlorophenols over different photocatalysts.

Amir Zada, Muhammad Khan, Muhammad Asim Khan, Qasim Khan, Aziz Habibi-Yangjeh, Alei Dang, Muhammad Maqbool,

Chlorophenols are very important environmental pollutants, which have created huge problems for both aquatic and terrestrial lives. Therefore, their removal needs urgent, effective, and advanced technologies to safeguard our environment for future generation. This review encompasses a comprehensive study of the applications of chlorophenols, their hazardous effects and photocatalytic degradation ... Read more >>

Environ Res (Environmental research)
[2021, 195:110742]

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Retraction Note to: A Comparative Study of the Toxicity of Polyethylene Glycol-Coated Cobalt Ferrite Nanospheres and Nanoparticles.

Shahnaz Akhtar, Qasim Khan, Shahzad Anwar, Ghafar Ali, Muhammad Maqbool, Maaz Khan, Shafqat Karim, Lan Gao,

An amendment to this paper has been published and can be accessed via the original article. ... Read more >>

Nanoscale Res Lett (Nanoscale research letters)
[2020, 15(1):208]

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Correction to "Life-Cycle Assessment of Gingko-Wood Three-Dimensional Membrane for Wastewater Treatment".

Faiza Niaz, Qasim Khan, Mustafa Ali, Wenxing Shen,

[This corrects the article DOI: 10.1021/acsomega.9b03722.]. ... Read more >>

ACS Omega (ACS omega)
[2020, 5(42):27733]

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Moment-Based Analysis of Reg. Triangular QAM in Turbulent Atmospheric Channels with Pointing Errors incorporates Zero and Non-zero Boresight

Muhammad Nabeel Shahid, Furqan Haider Qureshi, Shahzad Amin Sheikh, Qasim Umar Khan, Muhammad Zeeshan,

In recent years, free-space optical (FSO) technology has gained fame in communication systems due to its high data rates and license-free feature. Triangular quadrature amplitude modulation (TQAM) is an efficient modulation scheme that uses even bits per symbol, and it has a low average symbol error rate (ASER) than square ... Read more >>

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Structure optimization of perovskite quantum dot light-emitting diodes.

Qasim Khan, Alagesan Subramanian, Guannan Yu, Khan Maaz, Delong Li, Rizwan Ur Rehman Sagar, Keqiang Chen, Wei Lei, Babar Shabbir, Yupeng Zhang,

Although all-inorganic perovskite light emitting diodes (PeLED) have satisfactory stability under an ambient atmosphere, producing devices with high performance is challenging. A device architecture with a reduced energy barrier between adjacent layers and optimized energy level alignment in the PeLED is critical to achieve high electroluminescence efficiency. In this study, ... Read more >>

Nanoscale (Nanoscale)
[2019, 11(11):5021-5029]

Cited: 4 times

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Prevalence of QTc interval prolongation and its associated risk factors among psychiatric patients: a prospective observational study.

Zahid Ali, Mohammad Ismail, Zahid Nazar, Fahadullah Khan, Qasim Khan, Sidra Noor,

BACKGROUND:QT interval prolongation is a growing concern worldwide, posing psychiatric patients to life-threatening fatal arrhythmias i.e., torsade de pointes. This study aimed to identify the prevalence of QT interval prolongation, its associated risk factors and prescribing patterns of QT prolonging drugs among psychiatric patients. METHOD:A prospective observational study was conducted ... Read more >>

BMC Psychiatry (BMC psychiatry)
[2020, 20(1):277]

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Incidence of suboptimal response to tumor necrosis factor antagonist therapy in inflammatory bowel disease in newly industrialised countries: The EXPLORE study.

Jesus K Yamamoto-Furusho, Othman Al Harbi, Alessandro Armuzzi, Webber Chan, Enrique Ponce de Leon, Jiaming Qian, Marina Shapina, Murat Toruner, Chia-Hung Tu, Byong Duk Ye, Morgane Guennec, Cecilia Sison, Dirk Demuth, Olga Fadeeva, Qasim M Rana Khan,

<h4>Background</h4>Incidence of inflammatory bowel disease (IBD) is increasing in newly industrialised countries (NICs); however, data on suboptimal response to anti-tumor necrosis factor (anti-TNF) agents are limited.<h4>Objectives</h4>To assess incidence and indicators of suboptimal response to first anti-TNF therapy in IBD patients in NICs.<h4>Methods</h4>A chart review was conducted in ten countries from ... Read more >>

Dig Liver Dis (Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver)
[2020, 52(8):869-877]

Cited: 2 times

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Synthesis and optical applications of low dimensional metal-halide perovskites.

Jingying Liu, Keqiang Chen, Sayed Ali Khan, Babar Shabbir, Yupeng Zhang, Qasim Khan, Qiaoliang Bao,

Metal halide perovskites have received substantial attention in research communities due to their outstanding efficiency achievements in the field of photovoltaics, optoelectronics and electronics, exhibiting extraordinary optical, electrical and mechanical properties. The exceptional structural tunability enables perovskite material to possess low-dimensional form at the atomic level and extends their applications ... Read more >>

Nanotechnology (Nanotechnology)
[2020, 31(15):152002]

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Productivity and Stability of Multi-Species Cover Crop Mixtures in the Northern Great Plains

Qasim A Khan, Kent A McVay,

Mixed species cover crops are a relatively recent crop management method for improving soil health and cropping system sustainability. This 2-yr study assessed the productivity and stability of cover crop mixtures with multi-species functional groups compared with single species cover crops. Selection criteria were developed to identify suitable cover crops ... Read more >>

Agron J (Agronomy journal)
[2019, 111(4):1817-1827]

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Superior Magnetoresistance Performance of Hybrid Graphene Foam/Metal Sulfide Nanocrystal Devices.

M Husnain Zeb, Babar Shabbir, Rizwan Ur Rehman Sagar, Nasir Mahmood, Keqiang Chen, Irfan Qasim, Muhammad Imran Malik, Wenzhi Yu, M Mosarof Hossain, Zhigao Dai, Qingdong Ou, Masroor A Bhat, Bannur Nanjunda Shivananju, Yun Li, Xian Tang, Kun Qi, Adnan Younis, Qasim Khan, Yupeng Zhang, Qiaoliang Bao,

Interfaces between metals and semiconducting materials can inevitably influence the magnetotransport properties, which are crucial for technological applications ranging from magnetic sensing to storage devices. By taking advantage of this, a metallic graphene foam is integrated with semiconducting copper-based metal sulfide nanocrystals, i.e., Cu<sub>2</sub>ZnSnS<sub>4</sub> (copper-zinc-tin-sulfur) without direct chemical bonding and ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2019, 11(21):19397-19403]

Cited: 1 time

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A Color Tunable Quantum-Dot Light-Emitting Diode Device Driven by Variable Voltage.

Khan Qasim, Zhang Zhenbo, Naresh Kumar Khatri, Qingshan Xu, Alagesan Subramanian, Li Qing, Lei Wei,

A hole transporting layer (HTL) consisting of poly[(9,9-dioctylfluorenyl-2,7-diyl)-co-(4,4'-(<i>N</i>-(4-sec-butylphenyl)diphenylamine)] doped with 4,4'-Bis(9H-carbazol-9-yl)biphenyl was designed for high-performance multicolor quantum-dot light-emitting diode (QLED) fabricated by an all-solution process technique. The band structure of the HTL is tailored via small molecule doping to create a cascade of highest occupied molecular orbital levels (HOMO) from ... Read more >>

J Nanosci Nanotechnol (Journal of nanoscience and nanotechnology)
[2019, 19(2):1038-1043]

Cited: 1 time

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Potential drug-drug interactions in outpatient department of a tertiary care hospital in Pakistan: a cross-sectional study.

Mohammad Ismail, Sidra Noor, Umme Harram, Inamul Haq, Iqbal Haider, Faiza Khadim, Qasim Khan, Zahid Ali, Tahir Muhammad, Muhammad Asif,

<h4>Background</h4>Potential drug-drug interactions (pDDIs) are one of the preventable drug related problems having the risk of serious adverse events or therapeutic failure. In developing countries like Pakistan, this issue remains poorly addressed. The objective of this study was to explore prevalence of pDDIs in the Outpatient Department (OPD) of a ... Read more >>

BMC Health Serv Res (BMC health services research)
[2018, 18(1):762]

Cited: 3 times

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Moxifloxacin-induced QT interval prolongation and torsades de pointes: a narrative review.

Fahadullah Khan, Mohammad Ismail, Qasim Khan, Zahid Ali,

<h4>Introduction</h4>Moxifloxacin is widely used for the treatment of a number of infectious diseases because of its favorable pharmacological profile and high clinical success rate. However, it is often criticized for its higher risk of QTc interval prolongation (QTIP) and torsades de pointes (TdP).<h4>Areas covered</h4>A review of published literature on moxifloxacin-related ... Read more >>

Expert Opin Drug Saf (Expert opinion on drug safety)
[2018, 17(10):1029-1039]

Cited: 6 times

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High prevalence of the risk factors for QT interval prolongation and associated drug-drug interactions in coronary care units.

Qasim Khan, Mohammad Ismail, Iqbal Haider,

<h4>Objectives</h4>Patients admitted in coronary care units are susceptible to QT interval prolongation due to numerous risk factors. The purpose of this study was to identify the prevalence of risk factors for QT interval prolongation; QT prolonging medications; drug-drug interactions; their predictors; and torsades de pointes risks of drugs.<h4>Methods</h4>After obtaining approval, ... Read more >>

Postgrad Med (Postgraduate medicine)
[2018, 130(8):660-665]

Cited: 2 times

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CHIP E3 ligase mediates proteasomal degradation of the proliferation regulatory protein ALDH1L1 during the transition of NIH3T3 fibroblasts from G0/G1 to S-phase.

Qasim A Khan, Peter Pediaditakis, Yuryi Malakhau, Amin Esmaeilniakooshkghazi, Zahra Ashkavand, Valentin Sereda, Natalia I Krupenko, Sergey A Krupenko,

ALDH1L1 is a folate-metabolizing enzyme abundant in liver and several other tissues. In human cancers and cell lines derived from malignant tumors, the ALDH1L1 gene is commonly silenced through the promoter methylation. It was suggested that ALDH1L1 limits proliferation capacity of the cell and thus functions as putative tumor suppressor. ... Read more >>

PLoS One (PloS one)
[2018, 13(7):e0199699]

Cited: 6 times

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Interfacial Energy-Level Alignment for High-Performance All-Inorganic Perovskite CsPbBr3 Quantum Dot-Based Inverted Light-Emitting Diodes.

Alagesan Subramanian, Zhenghui Pan, Zhenbo Zhang, Imtiaz Ahmad, Jing Chen, Meinan Liu, Shuang Cheng, Yijun Xu, Jun Wu, Wei Lei, Qasim Khan, Yuegang Zhang,

All-inorganic perovskite light-emitting diode (PeLED) has a high stability in ambient atmosphere, but it is a big challenge to achieve high performance of the device. Basically, device design, control of energy-level alignment, and reducing the energy barrier between adjacent layers in the architecture of PeLED are important factors to achieve ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2018, 10(15):13236-13243]

Cited: 4 times

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Camelina sativa as a fallow replacement crop in wheat-based crop production systems in the US Great Plains

Augustine K Obour, Reza K Afshar, Chengci Chen, Qasim Khan, Peggy Lamb, Kent McVay, Yesuf A Mohammed, Eric Obeng, Henry Y Sintim, Valtcho D Zheljazkov,

Oilseed camelina (Camelina sativa [L.] Crantz) has potential to diversify and intensify dryland wheat-based crop production in the US Great Plains. Field experiments were conducted to evaluate camelina as a fallow replacement crop in winter wheat (Triticum aestivum L) − fallow (W-F) crop rotation system across five locations in the ... Read more >>

(Industrial crops and products.)
[2018, 111:22-29]

Cited: 1 time

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Prevalence of the risk factors for QT prolongation and associated drug-drug interactions in a cohort of medical inpatients.

Qasim Khan, Mohammad Ismail, Iqbal Haider, Zahid Ali,

BACKGROUND/PURPOSE:Medical inpatients are at increased risk of QT interval prolongation due to multiple risk actors and QT prolonging drugs. This study aimed to identify the prevalence of risk factors for QT prolongation; QT prolonging medications; associated drug-drug interactions (QT-DDIs); their predictors; and TdP (torsades de pointes) risks of drugs. METHODS:This ... Read more >>

J Formos Med Assoc (Journal of the Formosan Medical Association = Taiwan yi zhi)
[2019, 118(1 Pt 1):109-115]

Cited: 1 time

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Prevalence of QT interval prolonging drug-drug interactions (QT-DDIs) in psychiatry wards of tertiary care hospitals in Pakistan: a multicenter cross-sectional study.

Qasim Khan, Mohammad Ismail, Iqbal Haider, Fahadullah Khan,

Background QT prolongation and associated arrhythmias, torsades de pointes (TdP), are considerable negative outcomes of many antipsychotic and antidepressant agents frequently used by psychiatric patients. Objective To identify the prevalence, levels, and predictors of QT prolonging drug-drug interactions (QT-DDIs), and AZCERT (Arizona Center for Education and Research on Therapeutics) classification ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2017, 39(6):1256-1264]

Cited: 4 times

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Frequency, characteristics and risk factors of QT interval prolonging drugs and drug-drug interactions in cancer patients: a multicenter study.

Qasim Khan, Mohammad Ismail, Sehrash Khan,

BACKGROUND:Cancer patients may receive a high number of medications with the potential to prolong QT interval and subsequent TdP (torsades de pointes). This study aimed to identify the prevalence of QT prolonging drugs, their TdP risk, QT prolonging drug-drug interactions (QT-DDIs), levels, predictors, and TdP risk of drugs involved in ... Read more >>

BMC Pharmacol Toxicol (BMC pharmacology & toxicology)
[2017, 18(1):75]

Cited: 5 times

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QT interval prolongation in hospitalized patients on cardiology wards: a prospective observational study.

Qasim Khan, Mohammad Ismail, Iqbal Haider, Inam Ul Haq, Sidra Noor,

<h4>Purpose</h4>Prolonged QT interval may lead to a lethal form of arrhythmia, torsades de pointes (TdP), which is associated with cardiovascular mortality. Therefore, we aimed to identify prevalence of QT interval prolongation, compare clinical characteristics of patients with normal and prolonged QT interval, and identify predictors of QT interval prolongation.<h4>Methods</h4>A prospective ... Read more >>

Eur J Clin Pharmacol (European journal of clinical pharmacology)
[2017, 73(11):1511-1518]

Cited: 5 times

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