Full Text Journal Articles by
Author Priscilia Lianto

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Associations between liver X receptor polymorphisms and blood lipids: A systematic review and meta-analysis.

Huifeng Zhang, Priscilia Lianto, Weiming Li, Mengfan Xu, J Bernadette Moore, James L Thorne,

Genetic susceptibility to dyslipidaemia remains incompletely understood. The liver X receptors (LXRs), members of the nuclear receptor superfamily of ligand dependent transcription factors, are homeostatic regulators of lipid metabolism. Multiple single nucleotide polymorphisms (SNPs)have been identified previously in the coding and regulatory regions of the LXRs. The aim of this systematic review ... Read more >>

Steroids (Steroids)
[2022, 185:109057]

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Characterization and prognostic value of LXR splice variants in triple-negative breast cancer.

Priscilia Lianto, Samantha A Hutchinson, J Bernadette Moore, Thomas A Hughes, James L Thorne,

Activity of liver x receptor (LXR), the homeostatic regulator of cholesterol metabolism, is elevated in triple-negative breast cancer (BCa) relative to other BCa subtypes, driving drug resistance and metastatic gene signatures. The loci encoding LXRα and LXRβ produce multiple alternatively spliced proteins, but the true range of variants and their ... Read more >>

iScience (iScience)
[2021, 24(10):103212]

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