Full Text Journal Articles by
Author Prashant Bhangui

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Incorporating tumour biology to predict HCC recurrence in patients undergoing LDLT using expanded selection criteria.

Prashant Bhangui, Sanjiv Saigal, Dheeraj Gautam, Tarun Piplani, Narendra Choudhary, Rohan Chaudhary, Sanjay Yadav, S Thiagarajan, Amit Rastogi, Neeraj Saraf, Samiran Nundy, A S Soin,

Conventional selection criteria for liver transplantation in patients with hepatocellular carcinoma (HCC) based on tumour size and number alone, do not consider vital surrogates of tumor biology like alpha-fetoprotein (AFP) and tumour FDG-18 PET avidity. We follow an expanded selection criteria for living donor liver transplantation (LDLT) in patients with ... Read more >>

Liver Transpl (Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society)
[2020, :]

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Outcomes of Coronavirus Disease 2019 in Living Donor Liver Transplant Recipients.

Swapnil Dhampalwar, Sanjiv Saigal, Narendra Choudhary, Neeraj Saraf, Prashant Bhangui, Amit Rastogi, Srinivasan Thiagrajan, Arvinder S Soin,

Liver Transpl (Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society)
[2020, 26(12):1665-1666]

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Outcome of hepatitis C-related liver transplantation in direct-acting antiviral era.

Narendra S Choudhary, Neeraj Saraf, Sanjiv Saigal, Amit Rastogi, Prashant Bhangui, Srinivas Thiagrajan, Arvinder S Soin,

<h4>Background</h4>Hepatitis C virus (HCV) has become an easily treatable disease after the introduction of sofosbuvir-based direct-acting antiviral (DAA) regimens. This is a large single center experience of changing severity and outcome profile of HCV-related liver disease after availability of DAAs.<h4>Methods</h4>A retrospective analysis of prospectively collected liver transplantation (LT) database of ... Read more >>

Indian J Gastroenterol (Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology)
[2020, :]

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Restructuring Living Donor Liver Transplantation at a High Volume Center During the COVID-19 Pandemic.

Arvinder S Soin, Narendra S Choudhary, Sanjay K Yadav, Sanjiv Saigal, Neeraj Saraf, Amit Rastogi, Prashant Bhangui, Thiagarajan Srinivasan, Neelam Mohan, Sujeet K Saha, Ankur Gupta, Rohan J Chaudhary, Kamal Yadav, Swapnil Dhampalwar, Deepak Govil, Nikunj Gupta, Vijay Vohra,

<h4>Background</h4>Coronavirus disease 2019 (COVID-19) pandemic has led to deferral of elective transplants and pro-active pre-transplant testing of donor/recipient. The impact of these on living donor liver transplantation (LDLT) activity and outcome is not known. We performed LDLT only for sick or advanced hepatocellular carcinoma (HCC) patients in this period, with ... Read more >>

J Clin Exp Hepatol (Journal of clinical and experimental hepatology)
[2020, :]

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Experience With LDLT in Patients With Hepatocellular Carcinoma and Portal Vein Tumor Thrombosis Postdownstaging.

Arvinder S Soin, Prashant Bhangui, Tejinder Kataria, Sanjay S Baijal, Tarun Piplani, Dheeraj Gautam, Narendra S Choudhary, Srinivasan Thiagarajan, Amit Rastogi, Neeraj Saraf, Sanjiv Saigal,

<h4>Background</h4>Median survival in patients with hepatocellular carcinoma (HCC) and portal vein tumor thrombosis (PVTT) is 2-6 months; conventionally liver transplantation is contraindicated.<h4>Methods</h4>We studied outcomes following living donor liver transplantation (LDLT) post-PVTT downstaging (DS) with stereotactic body radiotherapy (SBRT), and tumor ablation (with transarterial chemo- or radio-embolization).<h4>Results</h4>Of 2348 consecutive LDLTs, 451 ... Read more >>

Transplantation (Transplantation)
[2020, 104(11):2334-2345]

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Pediatric liver transplantation in severe hepatopulmonary syndrome and use of inhaled nitric oxide for post-transplant hypoxemia-a single center experience.

Veena Raghunathan, Neelam Mohan, Maninder Dhaliwal, Prashant Bhangui, Vijay Vohra, Arvinder Singh Soin,

Data on pediatric patients with HPS undergoing LT are limited. Our aim was to study the spectrum and outcomes of pediatric patients with HPS undergoing LDLT. The role ofiNO for post-LDLT refractory hypoxemia was also assessed. Patients (aged < 18 years) undergoing LT were retrospectively studied. HPS was diagnosed based on European Respiratory ... Read more >>

Pediatr Transplant (Pediatric transplantation)
[2020, 24(7):e13792]

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Editorial: Bhangui commentary.

Prashant Bhangui,

Curr Opin Organ Transplant (Current opinion in organ transplantation)
[2020, 25(4):445]

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Proceedings of the 25th Annual Congress of the International Liver Transplantation Society.

Ryan Chadha, Eleonora De Martin, Gokhan Kabacam, Varvara Kirchner, Marit Kalisvaart, Nicolas Goldaracena, Tomohiro Tanaka, Michael Spiro, Gonzalo Sapisochin, Carmen Vinaixa, Amelia Hessheimer, Isabel Campos Varela, Ashwin Rammohan, Young-In Yoon, David Victor, Irene Scalera, Albert Chan, Prashant Bhangui,

The 25th Annual Congress of the International Liver Transplantation Society was held in Toronto, Canada, from May 15 to 18, 2019. Surgeons, hepatologists, anesthesiologists, critical care intensivists, radiologists, pathologists, and research scientists from all over the world came together with the common aim of improving care and outcomes for liver ... Read more >>

Transplantation (Transplantation)
[2020, 104(8):1560-1565]

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Biliary reconstruction and complications in living donor liver transplantation.

Dong-Hwan Jung, Toru Ikegami, Deniz Balci, Prashant Bhangui,

For a technically successful liver transplant (LT), secure bile duct anastomosis to prevent biliary complications (BC's) like biliary anastomotic stricture (BAS) and bile leak (BL) is mandatory. BC's after living donor liver transplantation (LDLT) are relatively more common compared to deceased donor LT (DDLT), particularly owing to surgical factors (small ... Read more >>

Int J Surg (International journal of surgery (London, England))
[2020, 82S:138-144]

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Current status of liver transplantation in Asia.

Taizo Hibi, Alfred Kow Wei Chieh, Albert Chi-Yan Chan, Prashant Bhangui,

In spite of early adoption of the brain death legislation, and all efforts at promoting deceased donation, various social, economic and cultural factors have acted as road blocks to the furthering of deceased donor liver transplantation (DDLT) in most Asian societies. On the other hand, Asian liver transplant centers have ... Read more >>

Int J Surg (International journal of surgery (London, England))
[2020, 82S:4-8]

Cited: 1 time

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Liver Transplantation for Hepatocellular Carcinoma. Working Group Report from the ILTS Transplant Oncology Consensus Conference.

Neil Mehta, Prashant Bhangui, Francis Y Yao, Vincenzo Mazzaferro, Christian Toso, Nobuhisa Akamatsu, Francois Durand, Jan Ijzermans, Wojciech Polak, Shusen Zheng, John P Roberts, Gonzalo Sapisochin, Taizo Hibi, Nancy Man Kwan, Mark Ghobrial, Avi Soin,

Liver transplantation (LT) offers excellent long-term outcome for certain patients with hepatocellular carcinoma (HCC), with a push to not simply rely on tumor size and number. Selection criteria should also consider tumor biology (including alpha-fetoprotein), probability of waitlist and post-LT survival (ie, transplant benefit), organ availability, and waitlist composition. These ... Read more >>

Transplantation (Transplantation)
[2020, 104(6):1136-1142]

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Delayed Graft Dysfunction due to Invasive Hepatic Mucormycosis After Living Donor Liver Transplantation.

Rohan J Chaudhary, Narendra S Choudhary, Neeraj Saraf, Dheeraj Gautam, Tarun Piplani, Srinivasan Thiagrajan, Prashant Bhangui, Sanjiv Saigal, Amit Rastogi, Arvinder S Soin,

Mucormycosis is a rare but emerging fungal infection complicating solid organ transplantation. It is associated with a high mortality rate. We describe an unusual case of hepatic mucormycosis in a living donor liver transplant recipient presenting as delayed graft dysfunction, which was successfully treated with combination of liposomal amphotericin B and ... Read more >>

J Clin Exp Hepatol (Journal of clinical and experimental hepatology)
[2020, 10(6):629-632]

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Current management of portal vein thrombosis in liver transplantation.

Prashant Bhangui, Eduardo S M Fernandes, Fabrizio Di Benedetto, Dong-Jin Joo, Silvio Nadalin,

Nontumoral portal vein thrombosis (PVT) is present at liver transplantation (LT) in 5-26% of cirrhotic patients, and is known to affect post LT outcomes. Up to 31% of patients who are found to have PVT at the time of LT, would have had PVT at the time of initial listing, ... Read more >>

Int J Surg (International journal of surgery (London, England))
[2020, 82S:122-127]

Cited: 1 time

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Safe Use of Right Lobe Live Donor Livers With up to 20% Macrovesicular Steatosis Without Compromising Donor Safety and Recipient Outcome.

Prashant Bhangui, Jayant Sah, Narendra Choudhary, Dheeraj Gautam, Vikas Gupta, Thiagrajan Srinivasan, Amit Rastogi, Tarun Piplani, Neeraj Saraf, Sanjiv Saigal, Avi Soin,

<h4>Background</h4>The principle in right lobe living donor liver transplantation is to use "near-perfect" grafts to maximize recipient benefit with minimal donor risk. Whether and what degree of graft macrovesicular steatosis is safe for both recipient and donor is debatable.<h4>Methods</h4>We compared donor and recipient outcomes in 623 primary right lobe living ... Read more >>

Transplantation (Transplantation)
[2020, 104(2):308-316]

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De Novo Malignancy After Living Donor Liver Transplantation: A Large Volume Experience.

Anisha Tiwari, Sanjiv Saigal, Narendra S Choudhary, Sujeet Saha, Amit Rastogi, Prashant Bhangui, Neeraj Saraf, Thiagrajan Srinivasan, Sanjay K Yadav, Dheeraj Gautam, Samiran Nundy, Arvinder S Soin,

<h4>Background and aims</h4>Liver transplantation (LT) recipients such as all organ transplant recipients, have a risk of developing de novo malignancies owing to prolonged immunosuppression. However, there is limited data on this after living donor liver transplantation (LDLT), wherein immunosuppression levels are less than in deceased donor transplantation. We aim to ... Read more >>

J Clin Exp Hepatol (Journal of clinical and experimental hepatology)
[2020, 10(5):448-452]

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Good Long-Term Outcomes in Patients With Primary Sclerosing Cholangitis Undergoing Living Donor Liver Transplantation.

Narendra S Choudhary, Sanjiv Saigal, Srikanth Thummala, Neeraj Saraf, Amit Rastogi, Prashant Bhangui, Thiagrajan Srinivasan, Sanjay K Yadav, Samiran Nundy, Arvinder S Soin,

<h4>Background</h4>Primary sclerosing cholangitis (PSC) is a progressive cholestatic disorder with liver transplantation (LT) being the only definitive treatment in end-stage disease. Recurrence of PSC after LT is a significant concern which can lead to graft loss. The aim of this study is to find out the disease recurrence and long-term ... Read more >>

J Clin Exp Hepatol (Journal of clinical and experimental hepatology)
[2020, 10(5):442-447]

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Proceedings of the 25th Annual Congress of the International Liver Transplantation Society.

Ryan Chadha, Eleonora De Martin, Gokhan Kabacam, Varvara Kirchner, Marit Kalisvaart, Nicolas Goldaracena, Tomohiro Tanaka, Michael Spiro, Gonzalo Sapisochin, Carmen Vinaixa, Amelia Hessheimer, Isabel Campos-Varela, Ashwin Rammohan, Young-In Yoon, David Victor, Irene Scalera, Albert Chan, Prashant Bhangui,

The 25th Annual Congress of the International Liver Transplantation Society (ILTS) was held in Toronto, Canada from May 15 to 18, 2019. Surgeons, hepatologists, anesthesiologists, critical care intensivists, radiologists, pathologists, and research scientists from all over the world came together with the common aim of improving care and outcomes for ... Read more >>

Transplantation (Transplantation)
[2020, :]

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Do Recipients of Genetically Related Donors Have Better Outcomes After Living Donor Liver Transplantation?

Narendra S Choudhary, Sujeet K Saha, Sanjiv Saigal, Dheeraj Gautam, Neeraj Saraf, Amit Rastogi, Prashant Bhangui, Srinivasan Thiagrajan, Arvinder S Soin,

<h4>Background</h4>There are few data on genetic relation of the donor and outcomes in living donor liver transplantation (LDLT) recipients. We compared outcomes of LDLT between recipients of genetically related and unrelated donors in a large single-center series.<h4>Methods</h4>The study included 1372 adult, ABO-compatible, primary LDLT recipients, who received a graft from ... Read more >>

J Clin Exp Hepatol (Journal of clinical and experimental hepatology)
[2020, 10(4):334-338]

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The high-end range of biliary reconstruction in living donor liver transplant.

Prashant Bhangui, Sujeet Saha,

<h4>Purpose of review</h4>To summarize recent evidence in literature regarding incidence and risk factors for biliary complications in living donor liver transplantation (LDLT), and current concepts in evaluation of donor biliary anatomy and surgical techniques of biliary reconstruction, to reduce the incidence of biliary complications.<h4>Recent findings</h4>Advances in biliary imaging in the ... Read more >>

Curr Opin Organ Transplant (Current opinion in organ transplantation)
[2019, 24(5):623-630]

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Novel classification of non-malignant portal vein thrombosis: A guide to surgical decision-making during liver transplantation.

Prashant Bhangui, Chetana Lim, Eric Levesque, Chady Salloum, Eylon Lahat, Cyrille Feray, Daniel Azoulay,

Non-tumoral portal vein thrombosis (PVT) is present at liver transplantation in 5% to 26% of cirrhotic patients, and the prevalence of complex PVT as defined here (grade 4 Yerdel, and grade 3,4 Jamieson and Charco) has been reported in 0% to 2.2%. Adequate portal inflow is mandatory to ensure graft ... Read more >>

J Hepatol (Journal of hepatology)
[2019, 71(5):1038-1050]

Cited: 3 times

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Is Portal Inflow Modulation Always Necessary for Successful Utilization of Small Volume Living Donor Liver Grafts?

Arvinder Singh Soin, Sanjay Kumar Yadav, Sujeet Kumar Saha, Amit Rastogi, Prashant Bhangui, Thiagarajan Srinivasan, Neeraj Saraf, Narendra S Choudhary, Sanjeev Saigal, Vijay Vohra,

Although the well-accepted lower limit of the graft-to-recipient weight ratio (GRWR) for successful living donor liver transplantation (LDLT) remains 0.80%, many believe grafts with lower GRWR may suffice with portal inflow modulation (PIM), resulting in equally good recipient outcomes. This study was done to evaluate the outcomes of LDLT with ... Read more >>

Liver Transpl (Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society)
[2019, 25(12):1811-1821]

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Living Donor Liver Transplantation for Acute-on-Chronic Liver Failure.

Sanjay Kumar Yadav, Neeraj Saraf, Narendra S Choudhary, Jayant Kumar Sah, Sujeet Kumar Sah, Amit Rastogi, Prashant Bhangui, Sanjiv Saigal, Arvinder Singh Soin,

Acute-on-chronic liver failure (ACLF) is a syndrome characterized by acute decompensation of previously diagnosed or undiagnosed liver disease with organ failure(s) with high short-term mortality. This study was conducted to report the outcomes of living donor liver transplantation (LDLT) in ACLF and assess the survival benefit of liver transplantation (LT) ... Read more >>

Liver Transpl (Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society)
[2019, 25(3):459-468]

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Report of the 24th Annual Congress of the International Liver Transplantation Society.

Eleonora De Martin, Amelia Hessheimer, Ryan Chadha, Gokhan Kabacam, Jeremy Rajanayagam, Varvara Kirchner, Marit Kalisvaart, Irene Scalera, Mamatha Bhat, Alan Contreras, Prashant Bhangui,

The 24th Joint Annual Congress of the International Liver Transplantation Society in association with European Liver and Intestine Transplant Association and Liver Intensive Care Group of Europe was held in Lisbon, Portugal from May 23 to 26, 2018. More than 1200 participants from over 60 countries including surgeons, hepatologists, anesthesiologists ... Read more >>

Transplantation (Transplantation)
[2019, 103(3):465-469]

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Good outcome of living donor liver transplantation for severe alcoholic hepatitis not responding to medical management: A single center experience of 39 patients.

Narendra S Choudhary, Sanjiv Saigal, Dheeraj Gautam, Neeraj Saraf, Amit Rastogi, Sanjay Goja, Prashant Bhangui, Srinivasan Thiagrajan, Sanjay K Yadav, Saurabh Mehrotra, Vipul Rastogi, Arvinder S Soin,

<h4>Introduction</h4>There are limited data on outcomes of living donor liver transplantation (LDLT) for patients with severe alcoholic hepatitis.<h4>Methods</h4>The study included LDLT recipients for severe alcoholic hepatitis (n = 39) who did not improve with medical treatment and compared their outcomes with patients who underwent LDLT for alcoholic liver disease (n = 461). The diagnosis ... Read more >>

Alcohol (Alcohol (Fayetteville, N.Y.))
[2019, 77:27-30]

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Accuracy of preoperative CT liver volumetry in living donor hepatectomy and its clinical implications.

Sanjay Goja, Sanjay Kumar Yadav, Amardeep Yadav, Tarun Piplani, Amit Rastogi, Prashant Bhangui, Sanjiv Saigal, Arvinder Singh Soin,

<h4>Background</h4>An accurate preoperative volumetric assessment of donor liver is essential for successful living donor liver transplant by ensuring adequate remnant and graft recipient weight ratio (GRWR).<h4>Methods</h4>The study cohort consisted of 744 right lobe (RL), 65 left lobe (LL) and 33 left lateral sector (LLS) grafts from July 2010 to January ... Read more >>

Hepatobiliary Surg Nutr (Hepatobiliary surgery and nutrition)
[2018, 7(3):167-174]

Cited: 3 times

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