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Author Pierre Simon Rohrlich

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Total body irradiation + fludarabine compared to busulfan + fludarabine as "reduced-toxicity conditioning" for patients with acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation in first complete remission: a study by the Acute Leukemia Working Party of the EBMT.

Sebastian Giebel, Myriam Labopin, Malgorzata Sobczyk-Kruszelnicka, Matthias Stelljes, Jenny L Byrne, Nathalie Fegueux, Dietrich W Beelen, Montserrat Rovira, Alexandros Spyridonidis, Didier Blaise, Martin Bornhäuser, Ihsan Karadogan, Bipin N Savani, Arnon Nagler, Mohamad Mohty, ,

The optimal conditioning for patients with acute myeloid leukemia in first complete remission treated with allogeneic hematopoietic cell transplantation (allo-HCT) has not been defined so far. In this retrospective study, we compared two "reduced-toxicity" regimens: intravenous busulfan at a total dose of 9.6 mg/kg (3 days) + fludarabine (Bu3/Flu) and total body irradiation ... Read more >>

Bone Marrow Transplant. (Bone marrow transplantation)
[2020, :]

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Identification of new F8 deep intronic variations in patients with haemophilia A.

Amy Dericquebourg, Yohann Jourdy, Mathilde Fretigny, Anne Lienhart, Ségolène Claeyssens, Catherine Ternisien, Pierre Boisseau, Pierre-Simon Rohrlich, Claude Négrier, Christine Vinciguerra,

INTRODUCTION:With current molecular diagnosis, about 1 to 5% of haemophilia A (HA) patients remain genetically unresolved. In these cases, deep intronic variation or structural variation disrupting the F8 gene could be causal. AIM:To identify the causal variation in four genetically unresolved mild-to-severe HA patients using an F8 mRNA analysis approach. ... Read more >>

Haemophilia (Haemophilia : the official journal of the World Federation of Hemophilia)
[2020, :]

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Correction to: A 1-Year Prospective French Nationwide Study of Emergency Hospital Admissions in Children and Adults with Primary Immunodeficiency.

Hélène Coignard-Biehler, Nizar Mahlaoui, Benoit Pilmis, Vincent Barlogis, Pauline Brosselin, Nathalie De Vergnes, Marianne Debré, Marion Malphettes, Pierre Frange, Emilie Catherinot, Isabelle Pellier, Isabelle Durieu, Antoinette Perlat, Bruno Royer, Alain Le Quellec, Eric Jeziorski, Alain Fischer, Olivier Lortholary, ,

The original version of the article contained error regarding the presentation of the institutional authors in the PDF and html versions. ... Read more >>

J Clin Immunol (Journal of clinical immunology)
[2020, 40(5):786-787]

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Pediatric randomized trial EORTC CLG 58951: Outcome for adolescent population with acute lymphoblastic leukemia.

Laura Olivier-Gougenheim, Chloe Arfeuille, Stefan Suciu, Nicolas Sirvent, Geneviève Plat, Alina Ferster, Barbara de Moerloose, Carine Domenech, Anne Uyttebroeck, Pierre-Simon Rohrlich, Helene Cavé, Yves Bertrand,

Over the years, the prognosis of adolescents treated for acute lymphoblastic leukemia (ALL) has improved. However, this age group still represents a challenge with an overall survival (OS) of 60% compared to 85% in younger children. Herein, we report the outcome of adolescents treated in the European Organisation for Research ... Read more >>

Hematol Oncol (Hematological oncology)
[2020, :]

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Chronic Granulomatous Disease with the McLeod Phenotype: a French National Retrospective Case Series.

Faustine Lhomme, Thierry Peyrard, Jérôme Babinet, Wadih Abou-Chahla, Isabelle Durieu, Despina Moshous, Bénédicte Neven, Pierre-Simon Rohrlich, Souha Albinni, Denise Amiranoff, Marie-Dominique Dumont, Olivier Lortholary, Sébastien Héritier, Christophe Marguet, Felipe Suarez, Alain Fischer, Stéphane Blanche, Olivier Hermine, Nizar Mahlaoui,

BACKGROUND:X-linked chronic granulomatous disease (CGD) is a primary immunodeficiency caused by mutations in the CYBB gene (located on Xp21.1). Patients with large deletions on chromosome Xp21.1 can present with the McLeod phenotype and also Duchenne muscular dystrophy or retinitis pigmentosa. The objective of the present study was to describe a ... Read more >>

J. Clin. Immunol. (Journal of clinical immunology)
[2020, 40(5):752-762]

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Impact of detectable measurable residual disease on umbilical cord blood transplantation.

Frédéric Baron, Myriam Labopin, Annalisa Ruggeri, Jorge Sierra, Stephen Robinson, Hélène Labussière-Wallet, Michael Potter, Josep-Maria Ribera, Eric Deconinck, Alessandro Rambaldi, Pierre-Simon Rohrlich, Thierry de Revel, Eliane Gluckman, Arnon Nagler, Mohamad Mohty,

The impact of measurable residual disease (MRD) on cord blood transplantation (CBT) outcomes has remained debated. To address this issue, we assessed the impact of measurable MRD at CBT on outcomes in large cohort of patients with acute leukemia. Inclusion criteria included adult patients with acute myeloid (AML) or acute ... Read more >>

Am. J. Hematol. (American journal of hematology)
[2020, :]

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COVID-19 and acute lymphoblastic leukemias of children and adolescents: First recommendations of the Leukemia committee of the French Society for the fight against Cancers and Leukemias in children and adolescents (SFCE).

André Baruchel, Yves Bertrand, Nicolas Boissel, Benoit Brethon, Stéphane Ducassou, Virginie Gandemer, Carine Halfon-Domenech, Thierry Leblanc, Guy Leverger, Gérard Michel, Arnaud Petit, Anne-France Ray-Lunven, Pierre-Simon Rohrlich, Pascale Schneider, Nicolas Sirvent, Marion Strullu, ,

Since the emergence of the SARS-CoV-2 infection, many recommendations have been made. However, the very nature of acute lymphoblastic leukemias and their treatment in children and adolescents led the Leukemia Committee of the French Society for the fight against cancers and leukemias in children and adolescents (SFCE) to propose more ... Read more >>

Bull Cancer (Bulletin du cancer)
[2020, 107(6):629-632]

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Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease.

Robert Zeiser, Nikolas von Bubnoff, Jason Butler, Mohamad Mohty, Dietger Niederwieser, Reuven Or, Jeff Szer, Eva M Wagner, Tsila Zuckerman, Bruyère Mahuzier, Judith Xu, Celine Wilke, Kunal K Gandhi, Gérard Socié, ,

BACKGROUND:Acute graft-versus-host disease (GVHD) remains a major limitation of allogeneic stem-cell transplantation; not all patients have a response to standard glucocorticoid treatment. In a phase 2 trial, ruxolitinib, a selective Janus kinase (JAK1 and JAK2) inhibitor, showed potential efficacy in patients with glucocorticoid-refractory acute GVHD. METHODS:We conducted a multicenter, randomized, ... Read more >>

N Engl J Med (The New England journal of medicine)
[2020, 382(19):1800-1810]

Cited: 7 times

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Acadesine Circumvents Azacitidine Resistance in Myelodysplastic Syndrome and Acute Myeloid Leukemia.

Thomas Cluzeau, Nathan Furstoss, Coline Savy, Wejdane El Manaa, Marwa Zerhouni, Lauriane Blot, Anne Calleja, Maeva Dufies, Alix Dubois, Clemence Ginet, Nicolas Mounier, Georges Garnier, Sophie Raynaud, Pierre Simon Rohrlich, Pierre Peterlin, Aspasia Stamatoullas, Fatiha Chermat, Pierre Fenaux, Arnaud Jacquel, Guillaume Robert, Patrick Auberger,

Myelodysplastic syndrome (MDS) defines a group of heterogeneous hematologic malignancies that often progresses to acute myeloid leukemia (AML). The leading treatment for high-risk MDS patients is azacitidine (Aza, Vidaza®), but a significant proportion of patients are refractory and all patients eventually relapse after an undefined time period. Therefore, new therapies ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2019, 21(1):]

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How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients?

Francine Garnache-Ottou, Chrystelle Vidal, Sabeha Biichlé, Florian Renosi, Eve Poret, Maïder Pagadoy, Maxime Desmarets, Anne Roggy, Estelle Seilles, Lou Soret, Françoise Schillinger, Sandrine Puyraimond, Tony Petrella, Claude Preudhomme, Christophe Roumier, Elisabeth A MacIntyre, Véronique Harrivel, Yohan Desbrosses, Bérengère Gruson, Franck Geneviève, Sylvain Thepot, Yuriy Drebit, Thibaut Leguay, François-Xavier Gros, Nicolas Lechevalier, Pascale Saussoy, Véronique Salaun, Edouard Cornet, Zehaira Benseddik, Richard Veyrat-Masson, Orianne Wagner-Ballon, Célia Salanoubat, Marc Maynadié, Julien Guy, Denis Caillot, Marie-Christine Jacob, Jean-Yves Cahn, Rémy Gressin, Johann Rose, Bruno Quesnel, Estelle Guerin, Franck Trimoreau, Jean Feuillard, Marie-Pierre Gourin, Adriana Plesa, Lucile Baseggio, Isabelle Arnoux, Norbert Vey, Didier Blaise, Romaric Lacroix, Christine Arnoulet, Blandine Benet, Véronique Dorvaux, Caroline Bret, Bernard Drenou, Agathe Debliquis, Véronique Latger-Cannard, Caroline Bonmati, Marie-Christine Bene, Pierre Peterlin, Michel Ticchioni, Pierre-Simon Rohrlich, Anne Arnaud, Stefan Wickenhauser, Valérie Bardet, Sabine Brechignac, Benjamin Papoular, Victoria Raggueneau, Jacques Vargaftig, Rémi Letestu, Daniel Lusina, Thorsten Braun, Vincent Foissaud, Jérôme Tamburini, Hind Bennani, Nicolas Freynet, Catherine Cordonnier, Magali Le Garff-Tavernier, Nathalie Jacques, Karim Maloum, Damien Roos-Weil, Didier Bouscary, Vahid Asnafi, Ludovic Lhermitte, Felipe Suarez, Etienne Lengline, Frédéric Féger, Giorgia Battipaglia, Mohamad Mohty, Sabrina Bouyer, Ouda Ghoual, Elodie Dindinaud, Caroline Basle, Mathieu Puyade, Carinne Lafon, Thierry Fest, Mikael Roussel, Xavier Cahu, Elsa Bera, Sylvie Daliphard, Fabrice Jardin, Lydia Campos, Françoise Solly, Denis Guyotat, Anne-Cécile Galoisy, Alice Eischen, Caroline Mayeur-Rousse, Blandine Guffroy, Christian Recher, Marie Loosveld, Alice Garnier, Vincent Barlogis, Maria Alessandra Rosenthal, Sophie Brun, Nathalie Contentin, Sébastien Maury, Mary Callanan, Christine Lefebvre, Natacha Maillard, Patricia Okamba, Christophe Ferrand, Olivier Adotevi, Philippe Saas, Fanny Angelot-Delettre, Delphine Binda, Eric Deconinck,

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive leukemia for which we developed a nationwide network to collect data from new cases diagnosed in France. In a retrospective, observational study of 86 patients (2000-2013), we described clinical and biological data focusing on morphologies and immunophenotype. We found ... Read more >>

Blood Adv (Blood advances)
[2019, 3(24):4238-4251]

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A 1-Year Prospective French Nationwide Study of Emergency Hospital Admissions in Children and Adults with Primary Immunodeficiency.

Hélène Coignard-Biehler, Nizar Mahlaoui, Benoit Pilmis, Vincent Barlogis, Pauline Brosselin, Nathalie De Vergnes, Marianne Debré, Marion Malphettes, Pierre Frange, Emilie Catherinot, Isabelle Pellier, Isabelle Durieu, Antoinette Perlat, Bruno Royer, Alain Le Quellec, Eric Jeziorski, Alain Fischer, Olivier Lortholary, , Laurent Aaron, Daniel Adoue, Claire Aguilar, Nathalie Aladjidi, Alexandre Alcais, Zahir Amoura, Philippe Arlet, Corinne Armari-Alla, Brigitte Bader-Meunier, Sophie Bayart, Yves Bertrand, Boris Bienvenu, Stéphane Blanche, Damien Bodet, Bernard Bonnotte, Raphaël Borie, Patrick Boutard, Claire Briandet, Jean-Paul Brion, Jacques Brouard, Sarah Cohen-Beaussant, Laurence Costes, Louis-Jean Couderc, Pierre Cougoul, Virginie Courteille, Geneviève de Saint Basile, Catherine Devoldere, Anne Deville, Jean Donadieu, Eric Dore, Fabienne Dulieu, Christine Edan, Natacha Entz-Werle, Claire Fieschi, Amandine Forestier, Fanny Fouyssac, Vincent Gajdos, Lionel Galicier, Virginie Gandemer, Martine Gardembas, Catherine Gaud, Gaelle Guillerm, Eric Hachulla, Mohamed Hamidou, Olivier Hermine, Cyrille Hoarau, Sébastien Humbert, Arnaud Jaccard, Serge Jacquot, Jean-Philippe Jais, Roland Jaussaud, Pierre-Yves Jeandel, Kamila Kebaili, Anne-Sophie Korganow, Olivier Lambotte, Fanny Lanternier, Claire Larroche, Anne-Sophie Lascaux, Emmanuelle Le Moigne, Vincent Le Moing, Yvon Lebranchu, Marc Lecuit, Guillaume Lefevre, Richard Lemal, Valérie Li Thiao Te, Aude Marie-Cardine, Nicolas Martin Silva, Agathe Masseau, Christian Massot, Françoise Mazingue, Etienne Merlin, Gérard Michel, Frédéric Millot, Béatrice Monlibert, Fabrice Monpoux, Despina Moshous, Luc Mouthon, Martine Munzer, Bénédicte Neven, Raphaëlle Nove-Josserand, Eric Oksenhendler, Marie Ouachée-Chardin, Caroline Oudot, Anne Pagnier, Jean-Louis Pasquali, Marlène Pasquet, Yves Perel, Capucine Picard, Christophe Piguet, Dominique Plantaz, Johan Provot, Pierre Quartier, Frédéric Rieux-Laucat, Pascal Roblot, Pierre-Marie Roger, Pierre-Simon Rohrlich, Hervé Rubie, Valéry Salle, Françoise Sarrot-Reynauld, Amélie Servettaz, Jean-Louis Stephan, Nicolas Schleinitz, Felipe Suarez, Laure Swiader, Sophie Taque, Caroline Thomas, Olivier Tournilhac, Caroline Thumerelle, François Tron, Jean-Pierre Vannier, Jean-François Viallard,

PURPOSE:Patients with primary immunodeficiency (PID) are at risk of serious complications. However, data on the incidence and causes of emergency hospital admissions are scarce. The primary objective of the present study was to describe emergency hospital admissions among patients with PID, with a view to identifying "at-risk" patient profiles. METHODS:We ... Read more >>

J Clin Immunol (Journal of clinical immunology)
[2019, 39(7):702-712]

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Hepatitis E and Allogeneic Hematopoietic Stem Cell Transplantation: A French Nationwide SFGM-TC Retrospective Study.

Aliénor Xhaard, Anne-Marie Roque-Afonso, Vincent Mallet, Patricia Ribaud, Stéphanie Nguyen-Quoc, Pierre-Simon Rohrlich, Reza Tabrizi, Johanna Konopacki, Séverine Lissandre, Florence Abravanel, Régis Peffault de Latour, Anne Huynh,

Usually self-limited, hepatitis E virus (HEV) infection may evolve to chronicity and cirrhosis in immunosuppressed patients. HEV infection has been described in solid-organ transplantation and hematology patients, but for allogeneic hematopoietic stem cell transplant (alloHSCT) recipients, only small cohorts are available. This retrospective nationwide multi-center series aimed to describe HEV ... Read more >>

Viruses (Viruses)
[2019, 11(7):]

Cited: 1 time

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Outcomes of Salvage Haploidentical Transplant with Post-Transplant Cyclophosphamide for Rescuing Graft Failure Patients: a Report on Behalf of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy.

Pedro H Prata, Matthieu Resche-Rigon, Didier Blaise, Gérard Socié, Pierre-Simon Rohrlich, Noel Milpied, Pascal Turlure, Stephanie Nguyen, Anne Sirvent, Claude-Eric Bulabois, Ana Berceanu, Amandine Charbonnier, Patrice Chevallier, Jacques-Olivier Bay, Benedicte Neven, Charlotte Jubert, Mohamad Mohty, Marie-Thérèse Rubio, Régis Peffault de Latour,

Prognosis of patients with graft failure is dismal, and retransplantation is the sole option for long-term survival. To address the interest of haploidentical transplantation as a salvage option in this context, we analyzed data from 24 patients with graft failure or loss retransplanted with a haploidentical donor who received post-transplant ... Read more >>

Biol. Blood Marrow Transplant. (Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation)
[2019, 25(9):1798-1802]

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Lymphoproliferative disease in patients with Wiskott-Aldrich syndrome: Analysis of the French Registry of Primary Immunodeficiencies.

Morgane Cheminant, Nizar Mahlaoui, Céline Desconclois, Danielle Canioni, Loïc Ysebaert, Loïc Dupré, Zilton Vasconcelos, Marion Malphettes, Despina Moshous, Bénédicte Neven, Pierre-Simon Rohrlich, Marc Bernard, Yves Bertrand, Alain Fischer, Felipe Suarez,

J. Allergy Clin. Immunol. (The Journal of allergy and clinical immunology)
[2019, 143(6):2311-2315.e7]

Cited: 0 times

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Comparison of Dynamic International Prognostic Scoring System and MYelofibrosis SECondary to PV and ET Prognostic Model for Prediction of Outcome in Polycythemia Vera and Essential Thrombocythemia Myelofibrosis after Allogeneic Stem Cell Transplantation.

Nico Gagelmann, Diderik-Jan Eikema, Liesbeth C de Wreede, Linda Koster, Christine Wolschke, Renate Arnold, Lothar Kanz, Grant McQuaker, Tony Marchand, Gerard Socié, Jean Henri Bourhis, Mohamad Mohty, Jan J Cornelissen, Patrice Chevallier, Paolo Bernasconi, Matthias Stelljes, Pierre-Simon Rohrlich, Renato Fanin, Jürgen Finke, Johan Maertens, Didier Blaise, Maija Itälä-Remes, Hélène Labussière-Wallet, Marie Robin, Donal McLornan, Yves Chalandon, Ibrahim Yakoub-Agha, Nicolaus Kröger, ,

We aimed to validate the MYelofibrosis SECondary to PV and ET prognostic model (MYSEC-PM) in 159 patients with myelofibrosis secondary to polycythemia vera (PV) and essential thrombocythemia (ET) from the European Society for Blood and Marrow Transplantation registry undergoing transplantation from matched siblings or unrelated donors. Furthermore, we aimed to ... Read more >>

Biol. Blood Marrow Transplant. (Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation)
[2019, 25(6):e204-e208]

Cited: 2 times

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Clinical Aspects of STAT3 Gain-of-Function Germline Mutations: A Systematic Review.

Alexandre Fabre, Sarah Marchal, Vincent Barlogis, Bernard Mari, Pascal Barbry, Pierre-Simon Rohrlich, Lisa R Forbes, Tiphanie P Vogel, Lisa Giovannini-Chami,

BACKGROUND:Signal transducer and activator of transcription 3 (STAT3) gain-of-function (GOF) germline mutations have been recently described. A comprehensive overview of this early-onset multiorgan autoimmune and lymphoproliferative disease has not yet been compiled. OBJECTIVE:We have conducted a systematic review of published STAT3 GOF cases to describe clinical, diagnostic, and therapeutic aspects ... Read more >>

J Allergy Clin Immunol Pract (The journal of allergy and clinical immunology. In practice)
[2019, 7(6):1958-1969.e9]

Cited: 6 times

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Genetic diagnosis of primary immunodeficiencies: A survey of the French national registry.

Nizar Mahlaoui, Capucine Picard, Perrine Bach, Laurence Costes, Virginie Courteille, Anja Ranohavimparany, Alexandre Alcaïs, Jean-Philippe Jais, Alain Fischer, ,

J. Allergy Clin. Immunol. (The Journal of allergy and clinical immunology)
[2019, 143(4):1646-1649.e10]

Cited: 2 times

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Scoring System Based on Post-Transplant Complications in Patients after Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndrome: A Study from the SFGM-TC.

Alexis Caulier, Elodie Drumez, Jordan Gauthier, Marie Robin, Didier Blaise, Yves Beguin, Mauricette Michallet, Patrice Chevallier, Jacques-Olivier Bay, Stéphane Vigouroux, Yohan Desbrosses, Jérôme Cornillon, Stéphanie Nguyen, Charles Dauriac, Régis Peffault de Latour, Bruno Lioure, Pierre-Simon Rohrlich, Martin Carré, Jean-Henri Bourhis, Anne Huynh, Felipe Suarez, Federico Garnier, Alain Duhamel, Ibrahim Yakoub-Agha,

PURPOSE:We developed a prognostic scoring system to evaluate the prognosis of myelodysplastic syndrome (MDS) patients surviving more than 100 days allogeneic hematopoietic cell transplantation after (allo-HCT). PATIENTS AND METHODS:We performed a landmark analysis on a derivation cohort of 393 cases to identify prognostic factors for 3-year overall survival. Potential predictor ... Read more >>

Curr Res Transl Med (Current research in translational medicine)
[2019, 67(1):8-15]

Cited: 0 times

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STAT3 Gain of Function: A New Kid on the Block in Interstitial Lung Diseases.

Alexandre Fabre, Sarah Marchal, Lisa Renee Forbes, Tiphanie Phillips Vogel, Vincent Barlogis, Valérie Triolo, Pierre-Simon Rohrlich, Etienne Bérard, Diane Frankel, Damien Ambrosetti, Christine Soler, Marie Hoflack, Marie Baque, Emmanuelle Bosdure, Mélisande Baravalle, Ania Carsin, Jean-Christophe Dubus, Lisa Giovannini-Chami,

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2018, 197(11):e22-e23]

Cited: 5 times

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Late effects after hematopoietic stem cell transplantation for β-thalassemia major: the French national experience.

Ilhem Rahal, Claire Galambrun, Yves Bertrand, Nathalie Garnier, Catherine Paillard, Pierre Frange, Corinne Pondarré, Jean Hugues Dalle, Regis Peffault de Latour, Mauricette Michallet, Dominique Steschenko, Despina Moshous, Patrick Lutz, Jean Louis Stephan, Pierre Simon Rohrlich, Ibrahim Yakoub-Agha, Françoise Bernaudin, Christophe Piguet, Nathalie Aladjidi, Catherine Badens, Claire Berger, Gérard Socié, Cécile Dumesnil, Marie Pierre Castex, Marilyne Poirée, Anne Lambilliotte, Caroline Thomas, Pauline Simon, Pascal Auquier, Gérard Michel, Anderson Loundou, Imane Agouti, Isabelle Thuret,

In this retrospective study, we evaluate long-term complications in nearly all β-thalassemia-major patients who successfully received allogeneic hematopoietic stem cell transplantation in France. Ninety-nine patients were analyzed with a median age of 5.9 years at transplantation. The median duration of clinical follow up was 12 years. All conditioning regimens were ... Read more >>

Haematologica (Haematologica)
[2018, 103(7):1143-1149]

Cited: 2 times

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An effective modestly intensive re-induction regimen with bortezomib in relapsed or refractory paediatric acute lymphoblastic leukaemia.

Gertjan J L Kaspers, Denise Niewerth, Bram A J Wilhelm, Peggy Scholte-van Houtem, Marta Lopez-Yurda, Johannes Berkhof, Jacqueline Cloos, Valerie de Haas, Ron A Mathôt, Andishe Attarbaschi, André Baruchel, Eveline S de Bont, Franca Fagioli, Claudia Rössig, Thomas Klingebiel, Barbara De Moerloose, Brigitte Nelken, Giuseppe Palumbo, Dirk Reinhardt, Pierre-Simon Rohrlich, Pauline Simon, Arend von Stackelberg, Christian Michel Zwaan,

This trial explored the efficacy of re-induction chemotherapy including bortezomib in paediatric relapsed/refractory acute lymphoblastic leukaemia. Patients were randomized 1:1 to bortezomib (1.3 mg/m2 /dose) administered early or late to a dexamethasone and vincristine backbone. Both groups did not differ regarding peripheral blast count on day 8, the primary endpoint. After ... Read more >>

Br. J. Haematol. (British journal of haematology)
[2018, 181(4):523-527]

Cited: 2 times

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Cord Blood Unit Dominance Analysis and Effect of the Winning Unit on Outcomes after Double-Unit Umbilical Cord Blood Transplantation in Adults with Acute Leukemia: A Retrospective Study on Behalf of Eurocord, the Cord Blood Committee of Cellular Therapy, Immunobiology Working Party, and the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation.

Karina Tozatto-Maio, Federica Giannotti, Myriam Labopin, Annalisa Ruggeri, Fernanda Volt, Annalisa Paviglianiti, Chantal Kenzey, Hiromi Hayashi, Jan Cornelissen, Mauricette Michallet, Dimitrios Karakasis, Eric Deconinck, Pierre-Simon Rohrlich, Regis Peffault de la Tour, Didier Blaise, Eefke Petersen, Maud D'Aveni, Henrik Sengeloev, Thierry Lamy, Nigel H Russell, Edouard Forcade, Charles F Craddock, Arnon Nagler, Eliane Gluckman, Vanderson Rocha,

Usually, after double umbilical cord blood transplantation (DUCBT), only 1 of the transplanted units persists in the long term. The characteristics of the winning cord blood unit (W-CBU) that determine unit dominance and how they influence the outcomes of DUCBT remain unclear. We retrospectively analyzed 347 patients with acute leukemia ... Read more >>

Biol. Blood Marrow Transplant. (Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation)
[2018, 24(8):1657-1663]

Cited: 1 time

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Better outcome with haploidentical over HLA-matched related donors in patients with Hodgkin's lymphoma undergoing allogeneic haematopoietic cell transplantation-a study by the Francophone Society of Bone Marrow Transplantation and Cellular Therapy.

Jordan Gauthier, Xavier Poiré, Anne-Claire Gac, Mathieu Leclerc, Thierry Guillaume, Yves Chalandon, Stéphanie Nguyen, Edouard Forcade, Caroline Régny, Jacques-Olivier Bay, Ali Bazarbachi, Pierre-Simon Rohrlich, Anne Huynh, Jonathan Farhi, Tony Marchand, Jean-Valère Malfuson, Sylvain Pilorge, Hélène Labussière-Wallet, Cécile Renard, Luc-Matthieu Fornecker, Marie Detrait, Rémy Duléry, Jérémy Delage, Anne-Lise Ménard, Amandine Charbonnier, Brigitte Nelken, Charlotte Jubert, Felipe Suarez, Régis Peffault de la Tour, Yves Beguin, Hélène Schoemans, Didier Blaise, Ibrahim Yakoub-Agha,

The question of the best donor type between haploidentical (HAPLO) and matched-related donors (MRD) for patients with advanced HL receiving an allogeneic hematopoietic cell transplantation (allo-HCT) is still debated. Given the lack of data comparing these two types of donor in the setting of non-myeloablative (NMA) or reduced-intensity (RIC) allo-HCT, ... Read more >>

Bone Marrow Transplant. (Bone marrow transplantation)
[2018, 53(4):400-409]

Cited: 5 times

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Chronic graft-versus-host disease features in double unit cord blood transplantation according to National Institutes of Health 2005 cGVHD Consensus criteria.

Hiromi Hayashi, Annalisa Ruggeri, Fernanda Volt, Jan J Cornelissen, Gerard Socié, Henrik Sengeloev, Mauricette Michallet, Dimitrios Karakasis, Eefke Petersen, Jean Yves Cahn, Hendrik Veelken, Mélanie Mercier, Pierre-Simon Rohrlich, Hanadi Rafii, Chantal Kenzey, Erick Xavier, Rafael F Duarte, Grzegorz W Basak, Vanderson Rocha, Eliane Gluckman, ,

Bone Marrow Transplant. (Bone marrow transplantation)
[2018, 53(4):417-421]

Cited: 0 times

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Hematopoietic stem cell transplantation for patients with paroxysmal nocturnal hemoglobinuria previously treated with eculizumab: a retrospective study of 21 patients from SFGM-TC centers.

Nicolas Vallet, Flore Sicre de Fontbrune, Michaël Loschi, Deborah Desmier, Alban Villate, Fiorenza Barraco, Patrice Chevallier, Louis Terriou, Ibrahim Yakoub-Agha, Annalisa Ruggeri, Mohamad Mohty, Natacha Maillard, Pierre-Simon Rohrlich, Patrice Ceballos, Stéphanie Nguyen, Xavier Poiré, Gaëlle Guillerm, Reza Tabrizi, Jonathan Farhi, Raynier Devillier, Marie-Thérèse Rubio, Gérard Socié, Régis Peffault de Latour, ,

Haematologica (Haematologica)
[2018, 103(3):e103-e105]

Cited: 3 times

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