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Atherosclerosis, inflammation and lipoprotein glomerulopathy in kidneys of apoE-/-/LDL-/- double knockout mice.

Alexander C Langheinrich, Marian Kampschulte, Franziska Scheiter, Christian Dierkes, Philip Stieger, Rainer M Bohle, Wolfgang Weidner,

<h4>Background</h4>The apoE-/-/LDL-/- double knockout mice are bearing considerable structural homology to human atherosclerosis. We hypothesized, that advanced lesion formation in the renal artery is associated with kidney alterations in these mice.<h4>Methods</h4>Kidneys from apoE-/-/LDL-/- double knockout mice at the age of 80 weeks (n = 6) and C57/BL control mice (n ... Read more >>

BMC Nephrol (BMC nephrology)
[2010, 11:18]

Cited: 10 times

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